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Oxford Biomedica (otc) (GB:OXB)
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Oxford BioMedica (OXB) AI Stock Analysis

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GB:OXB

Oxford BioMedica

(OTC:OXB)

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Neutral 46 (OpenAI - 4o)
Rating:46Neutral
Price Target:
563.00p
▼(-2.09% Downside)
The overall score is primarily influenced by financial performance challenges, including high leverage and negative profitability. Technical analysis provides some support with mixed momentum signals, but valuation remains a concern due to negative earnings.
Positive Factors
Revenue Growth
The company demonstrates robust revenue growth, which indicates a strong demand for its products and services, enhancing its market position and potential for future expansion.
Strategic Partnerships
Collaborations with major pharmaceutical companies provide financial stability and growth opportunities through milestone payments and royalties, strengthening its competitive edge.
Innovative Platform
The LentiVector® platform is a core asset, offering a competitive advantage in gene therapy development, positioning the company as a leader in advanced therapeutics.
Negative Factors
High Leverage
High leverage can strain financial resources and limit strategic flexibility, potentially impacting long-term operational stability and growth.
Profitability Challenges
Persistent profitability issues highlight operational inefficiencies, which may hinder the company's ability to reinvest in growth and innovation.
Cash Flow Issues
Negative cash flow indicates liquidity challenges, which could pressure future operations and limit the company's ability to fund new projects or manage debt.

Oxford BioMedica (OXB) vs. iShares MSCI United Kingdom ETF (EWC)

Oxford BioMedica Business Overview & Revenue Model

Company DescriptionOxford BioMedica (OXB) is a leading gene and cell therapy company based in the UK, specializing in the development and manufacture of advanced therapeutics for the treatment of serious diseases. The company operates primarily in the biopharmaceutical sector, focusing on its proprietary LentiVector® platform, which is utilized for the delivery of gene therapies. OXB's core products and services include the development of gene-based therapies for conditions such as cancer and neurological disorders, as well as offering contract development and manufacturing services to other biotech and pharmaceutical companies.
How the Company Makes MoneyOxford BioMedica generates revenue through a multifaceted business model that includes product sales, contract manufacturing, and collaborations. Key revenue streams consist of income from licensing agreements and partnerships with major pharmaceutical companies, where OXB receives milestone payments and royalties from the commercialization of therapies developed using its LentiVector® platform. Additionally, the company earns revenue from its contract manufacturing services, producing lentiviral vectors for third-party clients. Strategic collaborations with industry leaders enhance its financial stability and growth potential, contributing significantly to its earnings.

Oxford BioMedica Earnings Call Summary

Earnings Call Date:Apr 09, 2025
(Q4-2024)
|
% Change Since: |
Next Earnings Date:Sep 23, 2025
Earnings Call Sentiment Positive
The earnings call presented a positive outlook with significant revenue growth, increased client orders, operational efficiency improvements, and strategic expansions. However, challenges such as the operating EBITDA loss and negative working capital movement were noted.
Q4-2024 Updates
Positive Updates
Impressive Organic Revenue Growth
The company achieved an organic revenue growth of 81% and total revenues increased by 44% to GBP128.8 million in 2024.
Record Client Orders
The contracted value of client orders reached GBP186 million in 2024, a 35% increase from the previous year.
Operational Efficiency
Operating EBITDA loss narrowed significantly from GBP52.8 million in 2023 to GBP15.3 million in 2024, with a GBP5 million operating EBITDA profit in the second half of 2024.
Strong Commercial Momentum
The company reported significant growth in its pipeline, with a risk-adjusted pipeline growth of 61% from 2022 to 2024.
Successful FDA Inspection
The FDA inspection of the Oxford manufacturing site in July 2024 resulted in zero written observations, highlighting the quality management system.
Strategic Expansion and Rebranding
Completed acquisition of OXB in France, expanding operational footprint, and rebranded as OXB establishing a unified brand across geographies.
Negative Updates
Operating EBITDA Loss
Despite improvements, the company reported an operating EBITDA loss of GBP15.3 million for 2024.
Negative Working Capital Movement
The net cash outflow during 2024 was GBP42.1 million, largely driven by a negative working capital movement of GBP35.4 million.
Company Guidance
In the 2024 analyst briefing, OXB reported strong financial performance with an impressive organic revenue growth of 81%, resulting in total revenues of GBP128.8 million, a 44% increase from the previous year. Their pipeline expanded by 30% to $570 million, and customer orders grew by 35% to GBP186 million. The company achieved an operating EBITDA profit of GBP5 million in the second half of the year, narrowing their annual operating EBITDA loss to GBP15.3 million, a significant improvement from 2023's GBP52.8 million loss. For 2025, OXB expects revenues between GBP160 million and GBP170 million, with over 80% of this already covered by existing orders. The company plans to achieve a low single-digit million operating EBITDA profit, with a focus on continued margin expansion driven by operational efficiencies and strong commercial momentum.

Oxford BioMedica Financial Statement Overview

Summary
Oxford BioMedica shows strong revenue growth but faces significant profitability and cash flow challenges. High leverage and negative margins indicate financial instability, though the industry norm of high R&D costs may account for some losses.
Income Statement
45
Neutral
Oxford BioMedica's income statement reveals significant volatility in revenue and net income over the years. The most recent year shows a positive revenue growth of 43.84% from the previous year, but the company continues to face profitability challenges with a negative net profit margin of -33.53% and a negative gross profit margin of 40.65%. EBIT and EBITDA margins are also negative, indicating ongoing operational challenges.
Balance Sheet
50
Neutral
The balance sheet analysis shows a high level of debt relative to equity, with a debt-to-equity ratio of 1.91, posing a risk to financial stability. However, the equity ratio stands at 24.62%, reflecting some level of financial cushioning. Return on equity is negative due to sustained losses, highlighting profitability concerns.
Cash Flow
40
Negative
Cash flow analysis indicates negative free cash flow growth and operating cash flow, pointing to liquidity issues. The free cash flow to net income ratio is 1.35, suggesting that the company is not generating sufficient free cash flow to cover its net losses, which could put pressure on future operations.
BreakdownTTMDec 2024Dec 2023Dec 2022Dec 2021Dec 2020
Income Statement
Total Revenue151.21M128.80M89.54M139.99M142.80M87.73M
Gross Profit66.38M53.02M39.73M69.18M82.64M46.07M
EBITDA-1.07M-14.33M-148.62M-10.86M33.22M3.92M
Net Income-37.06M-43.19M-157.49M-39.16M19.01M-6.25M
Balance Sheet
Total Assets216.32M231.64M252.34M460.18M237.23M183.93M
Cash, Cash Equivalents and Short-Term Investments53.88M60.65M103.72M141.31M109.02M46.98M
Total Debt105.42M108.76M111.46M114.28M9.34M13.85M
Total Liabilities183.59M171.16M174.51M223.99M49.89M71.18M
Stockholders Equity32.73M57.05M74.01M204.65M187.34M112.75M
Cash Flow
Free Cash Flow-13.69M-58.12M-38.35M-28.91M15.99M-10.24M
Operating Cash Flow-9.50M-50.63M-28.52M-12.62M25.45M3.12M
Investing Cash Flow-4.63M5.63M2.81M-56.46M-9.46M-10.80M
Financing Cash Flow-12.63M2.91M-12.70M98.62M46.21M38.19M

Oxford BioMedica Technical Analysis

Technical Analysis Sentiment
Positive
Last Price575.00
Price Trends
50DMA
582.33
Positive
100DMA
476.01
Positive
200DMA
403.11
Positive
Market Momentum
MACD
4.15
Positive
RSI
54.28
Neutral
STOCH
33.91
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For GB:OXB, the sentiment is Positive. The current price of 575 is below the 20-day moving average (MA) of 606.35, below the 50-day MA of 582.33, and above the 200-day MA of 403.11, indicating a bullish trend. The MACD of 4.15 indicates Positive momentum. The RSI at 54.28 is Neutral, neither overbought nor oversold. The STOCH value of 33.91 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Positive sentiment for GB:OXB.

Oxford BioMedica Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
59
Neutral
£322.89M9.3615.04%1231.50%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
51
Neutral
£1.36B-26.01%22.03%20.01%
47
Neutral
£260.33M
46
Neutral
£732.06M-74.64%55.44%75.77%
46
Neutral
£101.18M-7.39-94.12%
39
Underperform
£112.27M-7.30-209.34%198.49%-26.66%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
GB:OXB
Oxford BioMedica
609.00
184.50
43.46%
GB:AVCT
Avacta Group plc
63.80
8.30
14.95%
GB:PRTC
PureTech Health
133.60
-18.80
-12.34%
GB:SCLP
Scancell Holdings
9.75
-4.75
-32.76%
GB:4BB
4basebio UK Societas
725.00
-625.00
-46.30%
GB:ONT
Oxford Nanopore Technologies PLC
143.40
1.60
1.13%

Oxford BioMedica Corporate Events

Other
Oxford Biomedica’s Chief Innovation Officer Executes Share Transactions
Neutral
Oct 20, 2025

Oxford Biomedica announced that its Chief Innovation Officer, Kyriacos Mitrophanous, exercised 26,210 LTIP options and sold the same number of shares at an average price of £5.758376 per share. This transaction, conducted on the London Stock Exchange, reflects ongoing managerial activities and may have implications for stakeholders monitoring insider transactions.

The most recent analyst rating on (GB:OXB) stock is a Buy with a £970.00 price target. To see the full list of analyst forecasts on Oxford BioMedica stock, see the GB:OXB Stock Forecast page.

Business Operations and StrategyExecutive/Board Changes
Oxford Biomedica Director Increases Stake, Signaling Confidence in Future Prospects
Positive
Oct 20, 2025

Oxford Biomedica announced that Dr. Heather Preston, a Non-Executive Director, has purchased 6,175 ordinary shares in the company. This transaction, conducted on the London Stock Exchange, highlights insider confidence in the company’s market position and future prospects. The purchase may positively influence stakeholder perceptions, reinforcing trust in the company’s strategic direction.

The most recent analyst rating on (GB:OXB) stock is a Buy with a £970.00 price target. To see the full list of analyst forecasts on Oxford BioMedica stock, see the GB:OXB Stock Forecast page.

Business Operations and StrategyExecutive/Board Changes
Oxford Biomedica Announces Board Change Amid Strategic Progress
Neutral
Oct 20, 2025

Oxford Biomedica announced the departure of Robert Ghenchev from its Board of Directors following his exit from Novo Holdings US. This change comes as the company continues to strengthen its position as a leading cell and gene therapy CDMO. Novo Holdings A/S, a major shareholder, retains the right to nominate a new director, subject to board approval, indicating ongoing strategic alignment and potential future developments.

The most recent analyst rating on (GB:OXB) stock is a Buy with a £970.00 price target. To see the full list of analyst forecasts on Oxford BioMedica stock, see the GB:OXB Stock Forecast page.

Regulatory Filings and Compliance
Oxford Biomedica’s Senior Executive Conducts Share Transactions
Neutral
Oct 16, 2025

Oxford Biomedica announced that Natalie Walter, Group General Counsel and Company Secretary, exercised 28,321 LTIP options and 39,679 DBP options, subsequently selling 68,000 shares at an average price of £6.116876 per share. This transaction, conducted on the London Stock Exchange, reflects the company’s adherence to EU Market Abuse Regulation requirements and highlights the ongoing financial activities of its senior management.

The most recent analyst rating on (GB:OXB) stock is a Buy with a £970.00 price target. To see the full list of analyst forecasts on Oxford BioMedica stock, see the GB:OXB Stock Forecast page.

Business Operations and StrategyM&A Transactions
Oxford BioMedica Expands US Operations with Key Acquisition
Positive
Oct 7, 2025

Oxford BioMedica (OXB) has expanded its US presence by acquiring a commercial-scale viral vector manufacturing facility in North Carolina from Resilience. This acquisition aligns with OXB’s strategy to enhance its US GMP capacity, meeting growing client demand and strengthening its global CDMO network. The facility will support late-stage programs and commercial launches, particularly in the adeno-associated virus field, and is expected to bolster OXB’s competitive position in the global viral vector market. The acquisition is anticipated to support OXB’s long-term growth outlook and maintain existing financial guidance, with integration planning already underway.

The most recent analyst rating on (GB:OXB) stock is a Buy with a £970.00 price target. To see the full list of analyst forecasts on Oxford BioMedica stock, see the GB:OXB Stock Forecast page.

Oxford Biomedica Reports Strong Revenue Growth in 2025
Sep 24, 2025

Oxford Biomedica, a leading cell and gene therapy contract development and manufacturing organization (CDMO), specializes in viral vector manufacturing and collaborates with pharmaceutical and biotechnology companies worldwide.

Business Operations and StrategyFinancial DisclosuresPrivate Placements and Financing
Oxford BioMedica Reports Robust H1 2025 Results, Strengthens Market Position
Positive
Sep 23, 2025

Oxford BioMedica reported strong financial results for the first half of 2025, with a 44% increase in revenues to £73.2 million, driven by high demand for its CDMO services. The company has improved its profitability significantly, reducing its operating EBITDA loss and strengthening its balance sheet with new financial facilities and share placements. The company’s strategic initiatives, including expanding its US commercial-scale GMP capacity, are set to support its growth trajectory and enhance its market position.

The most recent analyst rating on (GB:OXB) stock is a Buy with a £6.87 price target. To see the full list of analyst forecasts on Oxford BioMedica stock, see the GB:OXB Stock Forecast page.

Regulatory Filings and Compliance
Oxford Biomedica Announces Total Voting Rights Update
Neutral
Sep 1, 2025

Oxford Biomedica PLC announced that its issued share capital as of August 31, 2025, consists of 120,182,204 ordinary shares, with no shares held in treasury. This figure represents the total number of voting rights in the company and is relevant for shareholders determining their interest in OXB under the FCA’s rules. This announcement reflects OXB’s transparency in its operations and could impact shareholder decisions regarding their stakes in the company.

The most recent analyst rating on (GB:OXB) stock is a Buy with a £930.00 price target. To see the full list of analyst forecasts on Oxford BioMedica stock, see the GB:OXB Stock Forecast page.

Executive/Board ChangesRegulatory Filings and Compliance
Oxford Biomedica Director’s Share Transaction Error and Resolution
Neutral
Aug 22, 2025

Oxford Biomedica announced that Kay Davies, a Non-Executive Director, inadvertently purchased and then sold 4,563 shares due to an administrative error by her financial advisers. The transactions were reversed, and any gains from the trade will be donated to charity. This incident highlights the importance of compliance and transparency in financial dealings, reinforcing OXB’s commitment to regulatory standards.

The most recent analyst rating on (GB:OXB) stock is a Hold with a £532.00 price target. To see the full list of analyst forecasts on Oxford BioMedica stock, see the GB:OXB Stock Forecast page.

Delistings and Listing ChangesPrivate Placements and Financing
Oxford Biomedica Announces New Share Admission on LSE
Neutral
Aug 20, 2025

Oxford Biomedica has announced the admission of 13,921,114 new Ordinary Shares to the Main Market of the London Stock Exchange, following a successful placing and subscription. This increases the company’s total issued share capital to 120,173,462 ordinary shares, impacting the total voting rights and potentially affecting shareholder notifications under FCA rules.

The most recent analyst rating on (GB:OXB) stock is a Hold with a £532.00 price target. To see the full list of analyst forecasts on Oxford BioMedica stock, see the GB:OXB Stock Forecast page.

Business Operations and Strategy
Oxford Biomedica’s Chair Increases Stake with Significant Share Purchase
Positive
Aug 15, 2025

Oxford Biomedica announced that Dr. Roch Doliveux, Non-Executive Director and Chair of the company, purchased 67,000 ordinary shares on the London Stock Exchange. This transaction, valued at approximately £301,332.50, reflects a strategic move by a key company leader, potentially signaling confidence in the company’s market position and future prospects.

The most recent analyst rating on (GB:OXB) stock is a Buy with a £740.00 price target. To see the full list of analyst forecasts on Oxford BioMedica stock, see the GB:OXB Stock Forecast page.

Business Operations and StrategyPrivate Placements and Financing
Oxford Biomedica Raises £60 Million to Expand US Operations
Positive
Aug 15, 2025

Oxford Biomedica has successfully completed a placing of new ordinary shares, raising approximately £60 million. The funds will be used to expand its US commercial-scale capacity and improve process quality, addressing growing client demand across clinical phases. The placing was well-supported by both new and existing shareholders, and the shares are expected to be admitted to trading on the London Stock Exchange by 20 August 2025.

The most recent analyst rating on (GB:OXB) stock is a Buy with a £740.00 price target. To see the full list of analyst forecasts on Oxford BioMedica stock, see the GB:OXB Stock Forecast page.

Business Operations and StrategyPrivate Placements and Financing
Oxford Biomedica Announces £60 Million Equity Raise to Expand Global CDMO Network
Positive
Aug 14, 2025

Oxford Biomedica has announced a £60 million equity raise to fund strategic investments in expanding its global CDMO network, particularly in the US. This expansion is expected to accelerate revenue growth and improve margins, with projected revenues of £220-240 million in FY2026 and 25-30% year-on-year growth in 2027 and 2028. The company aims to enhance its manufacturing capabilities and service offerings to meet growing client demand, positioning itself for stronger profitability and a larger share of the viral vector market.

The most recent analyst rating on (GB:OXB) stock is a Buy with a £740.00 price target. To see the full list of analyst forecasts on Oxford BioMedica stock, see the GB:OXB Stock Forecast page.

Regulatory Filings and Compliance
Oxford Biomedica Announces Total Voting Rights Update
Neutral
Aug 1, 2025

Oxford Biomedica announced that its total issued share capital consists of 106,199,712 ordinary shares, with no shares held in treasury. This figure is crucial for shareholders to determine their interest in the company under the FCA’s rules, impacting how they manage their investments and disclosures.

The most recent analyst rating on (GB:OXB) stock is a Buy with a £740.00 price target. To see the full list of analyst forecasts on Oxford BioMedica stock, see the GB:OXB Stock Forecast page.

Business Operations and StrategyPrivate Placements and Financing
Oxford Biomedica Secures $125 Million Loan to Boost Growth Strategy
Positive
Aug 1, 2025

Oxford Biomedica has secured a new four-year loan facility of up to $125 million from Oaktree Capital Management to support its global CDMO operations and growth strategy. This financial move will refinance an existing $50 million loan and provide flexibility for future business needs, reinforcing OXB’s position in the cell and gene therapy industry and demonstrating Oaktree’s confidence in the company’s strategic objectives and market leadership.

The most recent analyst rating on (GB:OXB) stock is a Buy with a £740.00 price target. To see the full list of analyst forecasts on Oxford BioMedica stock, see the GB:OXB Stock Forecast page.

Business Operations and StrategyFinancial Disclosures
Oxford BioMedica Reports Strong H1 2025 Performance and Reiterates Full-Year Guidance
Positive
Jul 28, 2025

Oxford BioMedica PLC has reported a strong start to the fiscal year 2025, with revenues for the first half reaching £70-73 million, marking a 38%-44% increase compared to the same period in 2024. The company has secured £149 million in new orders during the first half of 2025, more than doubling the previous year’s figures, and has reiterated its full-year revenue guidance of £160-170 million. The company’s multi-vector, multi-site strategy is progressing well, with increased demand for its services and a strong order book providing confidence in future growth. OXB is expanding its manufacturing and development capacity to meet growing demand, particularly in late-stage lentiviral programs, and is enhancing its global operations to support clients across various geographies and development stages.

The most recent analyst rating on (GB:OXB) stock is a Buy with a £740.00 price target. To see the full list of analyst forecasts on Oxford BioMedica stock, see the GB:OXB Stock Forecast page.

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Oct 23, 2025