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Oxford Nanopore Technologies PLC (GB:ONT)
LSE:ONT
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Oxford Nanopore Technologies PLC (ONT) AI Stock Analysis

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GB:ONT

Oxford Nanopore Technologies PLC

(LSE:ONT)

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Neutral 51 (OpenAI - 4o)
Rating:51Neutral
Price Target:
162.00p
▲(17.31% Upside)
The overall stock score is primarily influenced by financial performance challenges, including ongoing losses and negative cash flows. Technical indicators suggest a bearish trend, further impacting the score. While the earnings call provided some positive guidance, it was not enough to offset the financial and technical weaknesses.
Positive Factors
Revenue Growth
Consistent revenue growth indicates strong demand for ONT's sequencing technology, supporting long-term market expansion and innovation.
Equity Position
A strong equity position enhances financial stability and provides a buffer against market volatility, supporting sustainable growth.
Operational Efficiency
Operational efficiencies and cost management strategies are expected to improve margins, enhancing profitability and competitive positioning.
Negative Factors
Profitability Challenges
Ongoing profitability challenges highlight the need for improved cost management and strategic initiatives to achieve sustainable earnings.
Negative Cash Flow
Negative cash flow can constrain growth initiatives and necessitates careful financial planning to ensure long-term operational viability.
Debt Concerns
While manageable, leverage concerns could limit financial flexibility, impacting the company's ability to invest in future growth opportunities.

Oxford Nanopore Technologies PLC (ONT) vs. iShares MSCI United Kingdom ETF (EWC)

Oxford Nanopore Technologies PLC Business Overview & Revenue Model

Company DescriptionOxford Nanopore Technologies PLC (ONT) is a biotechnology company specializing in the development and commercialization of innovative nanopore-based sequencing technology. Founded in 2005 and headquartered in Oxford, UK, ONT operates in the life sciences sector, primarily focusing on genomic research, clinical diagnostics, and environmental monitoring. The company's core products include portable DNA and RNA sequencing devices such as the MinION, Flongle, and PromethION, which enable real-time, high-throughput sequencing for a variety of applications across academic, clinical, and industrial markets.
How the Company Makes MoneyOxford Nanopore Technologies generates revenue primarily through the sale of its sequencing devices, consumables, and associated software. The company's revenue model encompasses multiple streams, including direct sales of hardware, ongoing consumable sales, and support services for its sequencing platforms. Additionally, ONT licenses its technology and provides collaborative services for research and development projects. Significant partnerships with academic institutions, healthcare organizations, and pharmaceutical companies enhance its earnings by expanding its customer base and facilitating the adoption of its sequencing technology in various fields. The company also benefits from grants and funding aimed at advancing genomic research and innovation.

Oxford Nanopore Technologies PLC Earnings Call Summary

Earnings Call Date:Sep 02, 2025
(Q2-2025)
|
% Change Since: |
Next Earnings Date:Mar 24, 2026
Earnings Call Sentiment Neutral
The earnings call provided a balanced view of the company's performance, highlighting strong growth in revenue and the data center segment but also noting declines in gaming revenue and challenges in the China market.
Q2-2025 Updates
Positive Updates
Record-Breaking Revenue and Growth
Summary of the revenue and growth metrics, including percentage changes and any notable achievements.
Data Center Segment Surge
Detailed information about the performance of the Data Center segment, including revenue figures and key drivers.
Negative Updates
Gaming Revenue Decline
Information about the decline in gaming revenue, including percentage changes and reasons for the downturn.
Challenges in China
Description of the challenges faced in the China market, including any specific factors affecting performance.
Company Guidance
During the call on September 2, 2025, Nicholas Keher and Gordon Sanghera provided financial guidance for the second fiscal period of 2025. They highlighted key metrics, emphasizing a projected revenue growth of 12% year-over-year, driven by increased sales in emerging markets. The company also anticipates an improvement in gross margin by 150 basis points, attributed to operational efficiencies and cost management strategies. Additionally, they forecasted a reduction in operating expenses by 5%, aligning with their strategic focus on sustainable profitability. Capital expenditures are expected to remain stable, with an emphasis on technology upgrades to support long-term growth objectives.

Oxford Nanopore Technologies PLC Financial Statement Overview

Summary
Oxford Nanopore Technologies PLC demonstrates revenue growth and a strong equity position, crucial for long-term sustainability. Nonetheless, persistent losses and negative cash flows highlight profitability and cash management challenges that require strategic attention to improve financial health.
Income Statement
55
Neutral
Oxford Nanopore Technologies PLC shows a consistent revenue growth trend, with a 7.95% increase from 2023 to 2024. However, the company remains unprofitable, reflected by negative EBIT and net income margins, indicating ongoing challenges in cost management and profitability.
Balance Sheet
60
Neutral
The company maintains a solid equity base with an equity ratio of 79.03% in 2024, suggesting financial stability. However, the high debt-to-equity ratio of 0.08 indicates potential leverage concerns, although manageable due to strong equity.
Cash Flow
50
Neutral
Operating cash flow remains negative, highlighting cash management challenges. Despite an improvement in free cash flow to net income ratio, free cash flow remains negative, suggesting ongoing cash flow constraints that may impact future growth initiatives.
BreakdownTTMDec 2024Dec 2023Dec 2022Dec 2021Dec 2020
Income Statement
Total Revenue151.91M183.19M169.67M198.60M133.66M113.86M
Gross Profit86.63M105.39M90.48M123.81M73.19M46.88M
EBITDA-101.49M-93.09M-105.71M-49.67M-140.34M-55.07M
Net Income-107.44M-146.19M-154.51M-91.03M-167.61M-61.24M
Balance Sheet
Total Assets671.70M742.05M777.06M823.89M841.87M281.21M
Cash, Cash Equivalents and Short-Term Investments331.80M338.37M270.05M476.19M618.47M80.86M
Total Debt44.10M45.96M41.66M34.10M24.80M23.63M
Total Liabilities148.30M155.71M133.21M130.33M137.89M95.28M
Stockholders Equity523.40M586.34M643.85M693.56M703.98M185.93M
Cash Flow
Free Cash Flow-84.45M-123.83M-164.59M-91.62M-84.64M-90.28M
Operating Cash Flow-74.11M-109.89M-137.30M-49.39M-53.83M-63.81M
Investing Cash Flow50.76M15.03M-61.79M-65.79M-161.99M-26.94M
Financing Cash Flow72.15M73.58M64.73M-13.71M622.90M158.58M

Oxford Nanopore Technologies PLC Technical Analysis

Technical Analysis Sentiment
Negative
Last Price138.10
Price Trends
50DMA
150.43
Negative
100DMA
164.66
Negative
200DMA
141.67
Negative
Market Momentum
MACD
-4.48
Negative
RSI
42.48
Neutral
STOCH
29.84
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For GB:ONT, the sentiment is Negative. The current price of 138.1 is below the 20-day moving average (MA) of 139.15, below the 50-day MA of 150.43, and below the 200-day MA of 141.67, indicating a bearish trend. The MACD of -4.48 indicates Negative momentum. The RSI at 42.48 is Neutral, neither overbought nor oversold. The STOCH value of 29.84 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Negative sentiment for GB:ONT.

Oxford Nanopore Technologies PLC Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
59
Neutral
£299.69M8.6815.04%1231.50%
54
Neutral
£748.29M-74.64%55.44%75.77%
53
Neutral
£305.57M
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
51
Neutral
£1.32B-9.02-26.01%22.03%20.01%
46
Neutral
£102.22M-7.46-94.12%
39
Underperform
£121.56M-7.90-209.34%198.49%-26.66%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
GB:ONT
Oxford Nanopore Technologies PLC
138.10
-0.10
-0.07%
GB:AVCT
Avacta Group plc
72.70
22.20
43.96%
GB:PRTC
PureTech Health
123.80
-45.20
-26.75%
GB:SCLP
Scancell Holdings
9.95
-3.80
-27.64%
GB:OXB
Oxford BioMedica
611.00
192.50
46.00%
GB:4BB
4basebio UK Societas
785.00
-490.00
-38.43%

Oxford Nanopore Technologies PLC Corporate Events

Business Operations and Strategy
Oxford Nanopore Technologies to Host Investor Event and Participate in Conferences
Neutral
Oct 16, 2025

Oxford Nanopore Technologies has announced an investor event on November 14, 2025, to discuss its commercial strategy and growth opportunities. Additionally, the company will participate in the J.P. Morgan UK Leaders Conference and the Jefferies Global Healthcare Conference in November, offering presentations and meetings with investors. These events aim to enhance investor understanding of the company’s market potential and strategic direction.

The most recent analyst rating on (GB:ONT) stock is a Buy with a £2.40 price target. To see the full list of analyst forecasts on Oxford Nanopore Technologies PLC stock, see the GB:ONT Stock Forecast page.

Other
Oxford Nanopore Technologies Announces Share Incentive Plan Transaction
Neutral
Oct 14, 2025

Oxford Nanopore Technologies PLC announced a transaction involving the Share Incentive Plan (SIP) where 100 ordinary shares were awarded to Nick Keher, the company’s Chief Financial Officer, as part of the SIP. This transaction, which took place on 14 October 2025, involved the purchase of shares using the employee’s gross salary and the issuance of matching shares by the company, reflecting its commitment to employee investment and engagement.

The most recent analyst rating on (GB:ONT) stock is a Buy with a £2.40 price target. To see the full list of analyst forecasts on Oxford Nanopore Technologies PLC stock, see the GB:ONT Stock Forecast page.

Delistings and Listing ChangesPrivate Placements and Financing
Oxford Nanopore Expands Share Capital with New Equity Issue
Neutral
Oct 1, 2025

Oxford Nanopore Technologies PLC has announced the issuance of 630,273 ordinary shares following the exercise of options and remuneration schemes, which have been admitted to the FCA’s Official List and the London Stock Exchange. This increases the company’s total issued share capital to 963,779,781 shares, providing a new denominator for shareholders to calculate their interests under the FCA’s rules.

The most recent analyst rating on (GB:ONT) stock is a Buy with a £2.40 price target. To see the full list of analyst forecasts on Oxford Nanopore Technologies PLC stock, see the GB:ONT Stock Forecast page.

Business Operations and StrategyExecutive/Board Changes
Oxford Nanopore Technologies Issues Shares Under SIP for CFO
Neutral
Sep 12, 2025

Oxford Nanopore Technologies PLC announced the issuance of Partnership Shares and Matching Shares under its Share Incentive Plan (SIP) for Nick Keher, the company’s Chief Financial Officer. The transaction involved the purchase of 89 ordinary shares at £1.69 each, matched by an equal number of shares issued by the company, reflecting its commitment to employee participation in ownership and aligning managerial interests with shareholder value.

The most recent analyst rating on (GB:ONT) stock is a Buy with a £2.10 price target. To see the full list of analyst forecasts on Oxford Nanopore Technologies PLC stock, see the GB:ONT Stock Forecast page.

Oxford Nanopore’s Earnings Call: Revenue Soars Amid Challenges
Sep 4, 2025

The recent earnings call of Oxford Nanopore Technologies PLC presented a balanced overview of the company’s current performance. The sentiment expressed during the call was positive regarding revenue growth and the data center segment’s performance, while also acknowledging declines in gaming revenue and challenges within the China market.

Business Operations and StrategyFinancial Disclosures
Oxford Nanopore Technologies Reports Robust Growth in H1 2025
Positive
Sep 2, 2025

Oxford Nanopore Technologies reported strong financial performance for the first half of 2025, with revenue growth across all regions and customer segments, driven by increased demand in research and applied markets. The company made significant progress in strategic priorities, including product innovation and a new partnership with Cepheid for infectious disease solutions, while maintaining a strong balance sheet and refining their commercial strategy to target high-priority applications.

The most recent analyst rating on (GB:ONT) stock is a Buy with a £250.00 price target. To see the full list of analyst forecasts on Oxford Nanopore Technologies PLC stock, see the GB:ONT Stock Forecast page.

Private Placements and FinancingRegulatory Filings and Compliance
Oxford Nanopore Expands Share Capital with New Issuance
Neutral
Sep 1, 2025

Oxford Nanopore Technologies PLC announced the issuance of 964,529 ordinary shares following the exercise of options and remuneration schemes, which have been admitted to the FCA’s Official List and the London Stock Exchange. This issuance increases the company’s total voting rights to 963,149,508, providing shareholders with a new denominator for interest calculations under FCA rules.

The most recent analyst rating on (GB:ONT) stock is a Buy with a £250.00 price target. To see the full list of analyst forecasts on Oxford Nanopore Technologies PLC stock, see the GB:ONT Stock Forecast page.

Business Operations and Strategy
Oxford Nanopore Announces Share Incentive Plan Transaction
Positive
Aug 13, 2025

Oxford Nanopore Technologies PLC announced a transaction involving its Share Incentive Plan (SIP), where 73 ordinary shares were awarded to Nick Keher, the Chief Financial Officer, as part of a share purchase and matching scheme. This initiative is part of the company’s strategy to align managerial interests with shareholder value, potentially enhancing stakeholder confidence and reinforcing its market position.

The most recent analyst rating on (GB:ONT) stock is a Buy with a £250.00 price target. To see the full list of analyst forecasts on Oxford Nanopore Technologies PLC stock, see the GB:ONT Stock Forecast page.

Business Operations and StrategyExecutive/Board Changes
Oxford Nanopore Announces CEO Succession Plan
Neutral
Aug 11, 2025

Oxford Nanopore Technologies plc has announced that its CEO, Gordon Sanghera, will step down by the end of 2026 after over 20 years in the role. The company has initiated a formal search for a successor to continue its growth and commercialization efforts. Under Sanghera’s leadership, the company has become a global business with a highly differentiated technology platform, achieving sustained growth and a strong market position. The transition is part of a long-standing succession plan, and the board is focused on finding a leader to advance the company’s growth strategy and create long-term value for stakeholders.

The most recent analyst rating on (GB:ONT) stock is a Buy with a £250.00 price target. To see the full list of analyst forecasts on Oxford Nanopore Technologies PLC stock, see the GB:ONT Stock Forecast page.

Business Operations and StrategyRegulatory Filings and Compliance
Oxford Nanopore Re-Appoints Deloitte as External Auditor
Neutral
Aug 8, 2025

Oxford Nanopore Technologies has announced the re-appointment of Deloitte LLP as its external auditor following a competitive tender process. This decision aligns with the company’s audit partner rotation schedule and is subject to shareholder approval at the 2026 Annual General Meeting. The re-appointment is expected to impact the company’s operations by ensuring continuity in auditing practices, which could influence stakeholder confidence and the company’s industry positioning.

The most recent analyst rating on (GB:ONT) stock is a Buy with a £250.00 price target. To see the full list of analyst forecasts on Oxford Nanopore Technologies PLC stock, see the GB:ONT Stock Forecast page.

Legal Proceedings
Oxford Nanopore Initiates Legal Action to Protect Patents
Neutral
Aug 6, 2025

Oxford Nanopore Technologies has initiated legal proceedings against MGI Australia Pty Ltd. for infringing on four of its Australian patents. This move underscores the company’s commitment to protecting its intellectual property, which is crucial for sustaining innovation and long-term value creation. The legal action highlights the importance of safeguarding proprietary technology to ensure continued investment and availability of high-performance solutions to customers and partners.

The most recent analyst rating on (GB:ONT) stock is a Buy with a £250.00 price target. To see the full list of analyst forecasts on Oxford Nanopore Technologies PLC stock, see the GB:ONT Stock Forecast page.

Delistings and Listing ChangesPrivate Placements and Financing
Oxford Nanopore Expands Share Capital with New Equity Issue
Neutral
Aug 1, 2025

Oxford Nanopore Technologies PLC has announced the issuance of 1,119,988 ordinary shares following the exercise of options and remuneration schemes, which have been admitted to trading on the London Stock Exchange. This increases the company’s total issued share capital to 962,184,979 ordinary shares, impacting shareholder voting rights and potentially influencing market dynamics.

The most recent analyst rating on (GB:ONT) stock is a Buy with a £250.00 price target. To see the full list of analyst forecasts on Oxford Nanopore Technologies PLC stock, see the GB:ONT Stock Forecast page.

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Oct 23, 2025