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10x Genomics Inc (TXG)
NASDAQ:TXG

10x Genomics (TXG) AI Stock Analysis

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10x Genomics

(NASDAQ:TXG)

Rating:60Neutral
Price Target:
$10.00
▲( 20.19% Upside)
10x Genomics receives a score of 60, reflecting a challenging financial performance with consistent net losses and profitability issues. While technical indicators suggest some potential for stabilization, valuation concerns are significant due to a negative P/E ratio. The earnings call and corporate events reveal mixed sentiment, with positive product growth overshadowed by uncertainties in funding and revenue guidance withdrawal.
Positive Factors
Litigation Settlement
The settlement agreement will provide 10x with a boost to its cash balance in the expected $68 million and potential future royalty payments.
Revenue Performance
Service revenue increased by 47% year-over-year, outperforming market expectations.
Sales Strategy
The company is expected to reaccelerate growth over time, particularly benefiting from a sales reorganization, and has a solid long-term runway in both the single-cell and spatial markets.
Negative Factors
Guidance Withdrawal
The company has withdrawn its FY25 guide due to current uncertainty and reduced visibility.
Instrument Sales
Instrument placements decreased significantly due to funding concerns in the US academic and government markets.
Market Uncertainty
TXG faces significant pressure from the US academic end-market, which accounts for 40-50% of TXG revenue.

10x Genomics (TXG) vs. SPDR S&P 500 ETF (SPY)

10x Genomics Business Overview & Revenue Model

Company Description10x Genomics, Inc., a life science technology company, develops and sells instruments, consumables, and software for analyzing biological systems in North America, Europe, the Middle East, Africa, China, and the Asia Pacific. The company provides chromium and chromium connect instruments, microfluidic chips, slides, reagents, and other consumables products. Its single cell solutions runs on its chromium instruments, which include single cell gene expression for measuring gene activity on a cell-by-cell basis; single cell immune profiling for measuring the activity of immune cells and their targets; single cell Assay for Transposase Accessible Chromati (ATAC) for measuring epigenetics comprising the physical organization of DNA; and single cell multiome ATAC + gene expression for measuring the genetic activity and epigenetic programming in the same cells across tens of thousands of cells in a single experiment. The company also provides visium spatial gene expression solution for measuring spatial gene expression patterns across a single tissue sample or gene expression and protein co-detection when combined with immunofluorescence. It serves various academic, government, biopharmaceutical, biotechnology, and other institutions. The company was formerly known as 10X Technologies, Inc. and changed its name to 10x Genomics, Inc. in November 2014. 10x Genomics, Inc. was incorporated in 2012 and is headquartered in Pleasanton, California.
How the Company Makes Money10x Genomics generates revenue through the sale of its proprietary instruments, consumables, and software to research institutions, pharmaceutical companies, and other entities engaged in life sciences research. The company offers a portfolio of products such as the Chromium Single Cell Platform, Visium Spatial Gene Expression, and software tools that facilitate data analysis and interpretation. Consumables, which are required for each experiment, represent a significant and recurring revenue stream for the company. Additionally, 10x Genomics may engage in strategic partnerships and collaborations that can provide supplementary revenue and enhance their market presence.

10x Genomics Key Performance Indicators (KPIs)

Any
Any
Instruments Revenue by Type
Instruments Revenue by Type
Shows revenue generated from different types of instruments, highlighting which products are driving sales and indicating the company's innovation and market demand.
Chart Insights10x Genomics' Chromium Instruments revenue is declining, reflecting broader challenges in the market, including reduced NIH funding and lower reaction prices. In contrast, Spatial Instruments have shown strong growth, driven by successful product launches like Visium HD and Xenium Prime 5K. However, recent quarters indicate a slowdown, aligning with a 51% drop in spatial instrument revenue in Q4 2024. Despite these challenges, the company remains committed to innovation and expects double-digit growth in spatial revenue in 2025, although NIH funding uncertainties pose a risk.
Data provided by:Main Street Data

10x Genomics Financial Statement Overview

Summary
10x Genomics faces significant challenges in achieving profitability and positive cash flows while maintaining a strong equity base. The company's substantial losses and declining revenue point to operational inefficiencies, yet its low leverage offers stability. The focus should be on improving operational efficiency and revenue growth to enhance financial health.
Income Statement
50
Neutral
10x Genomics has struggled with profitability, displaying negative EBIT and net income over recent years. The gross profit margin remains strong at around 68% for 2024, but the net profit margin is negative due to substantial operational losses. Revenue growth has been inconsistent, with a decline of 1.3% from 2023 to 2024, highlighting challenges in sustaining top-line growth.
Balance Sheet
60
Neutral
The company maintains a solid equity position with an equity ratio of approximately 77% for 2024, indicating low financial leverage. The debt-to-equity ratio remains low at 0.12, suggesting prudent debt management. However, the persistent negative net income has impacted return on equity, which stands at -25.7% in 2024.
Cash Flow
45
Neutral
Cash flows are concerning, with negative free cash flow due to ongoing capital expenditures and operational challenges. The operating cash flow to net income ratio is positive, indicating some operational cash flow generation, but free cash flow remains negative, posing liquidity risks.
Breakdown
Dec 2024Dec 2023Dec 2022Dec 2021Dec 2020
Income StatementTotal Revenue
610.78M618.73M516.41M490.49M298.85M
Gross Profit
414.48M409.31M396.02M416.40M240.38M
EBIT
-194.56M-194.95M-167.94M-52.91M-85.32M
EBITDA
-133.99M-205.11M-128.49M-24.59M-513.77M
Net Income Common Stockholders
-182.63M-255.10M-166.00M-58.22M-542.73M
Balance SheetCash, Cash Equivalents and Short-Term Investments
393.40M388.69M429.98M587.45M663.60M
Total Assets
918.64M965.14M1.03B1.02B929.34M
Total Debt
82.61M95.37M95.18M81.98M62.98M
Net Debt
-261.45M-263.91M-124.57M-505.47M-600.63M
Total Liabilities
208.50M224.10M223.24M201.26M190.27M
Stockholders Equity
710.13M741.04M805.74M817.57M739.07M
Cash FlowFree Cash Flow
-5.73M-64.72M-165.27M-122.65M-256.29M
Operating Cash Flow
6.66M-15.20M-33.61M-21.37M-217.90M
Investing Cash Flow
-32.63M133.49M-350.89M-106.73M-38.39M
Financing Cash Flow
10.91M13.67M15.82M35.30M468.91M

10x Genomics Technical Analysis

Technical Analysis Sentiment
Negative
Last Price8.32
Price Trends
50DMA
8.83
Negative
100DMA
11.16
Negative
200DMA
14.71
Negative
Market Momentum
MACD
0.07
Negative
RSI
44.44
Neutral
STOCH
31.61
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For TXG, the sentiment is Negative. The current price of 8.32 is below the 20-day moving average (MA) of 8.69, below the 50-day MA of 8.83, and below the 200-day MA of 14.71, indicating a bearish trend. The MACD of 0.07 indicates Negative momentum. The RSI at 44.44 is Neutral, neither overbought nor oversold. The STOCH value of 31.61 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Negative sentiment for TXG.

10x Genomics Risk Analysis

10x Genomics disclosed 70 risk factors in its most recent earnings report. 10x Genomics reported the most risks in the “Tech & Innovation” category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 3 New Risks
1.
Our past or future efforts to maintain and increase the effectiveness of our commercial organization may not succeed. Q4, 2024
2.
Our products generate large-scale complex data which requires advanced analytics to interpret. Q4, 2024
3.
AI and machine learning technologies may expose us to significant risks, including development and deployment challenges, regulatory uncertainties, competition for investor research and potential hard-to-predict changes to our business, which could adversely affect our business, results of operations and financial condition. Q4, 2024

10x Genomics Peers Comparison

Overall Rating
UnderperformOutperform
Sector (53)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
74
Outperform
$1.90B-0.25%9.37%95.72%
63
Neutral
$274.23M-19.80%4.88%37.87%
TXTXG
60
Neutral
$1.13B-22.03%-0.13%42.17%
54
Neutral
$1.58B-43.33%22.29%-32.89%
WGWGS
53
Neutral
$2.06B38.75-16.61%48.81%72.54%
53
Neutral
$5.24B3.07-43.58%2.80%16.87%-0.11%
51
Neutral
$192.47M-60.75%4.66%11.33%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
TXG
10x Genomics
8.32
-14.63
-63.75%
HCAT
Health Catalyst
3.74
-2.91
-43.76%
SDGR
Schrodinger
20.51
-1.31
-6.00%
CERT
Certara
11.17
-5.36
-32.43%
WGS
GeneDx Holdings
67.78
48.06
243.71%
SOPH
SOPHiA GENETICS
2.93
-1.81
-38.19%

10x Genomics Earnings Call Summary

Earnings Call Date:May 08, 2025
(Q1-2025)
|
% Change Since: -3.59%|
Next Earnings Date:Jul 31, 2025
Earnings Call Sentiment Neutral
The earnings call presented a mixed outlook. While there were significant achievements in consumables growth, particularly in APAC, and promising product developments, these were overshadowed by declines in instrument revenue and substantial uncertainties in the U.S. research funding environment. The company's decision to withdraw full-year guidance reflects this uncertainty.
Q1-2025 Updates
Positive Updates
Strong Consumables Revenue Growth
Total consumables revenue increased 5% year-over-year to $115.4 million, with spatial consumables revenue up 18%, driven by Xenium consumables.
Robust Demand in APAC
Revenue in the APAC region increased by 22%, with strong consumable sales offsetting declines in other areas.
Cost Reduction Measures
The company implemented cost-saving measures, including an 8% reduction in global workforce and significant reductions in non-headcount expenses, expected to reduce 2025 operating expenses by more than $50 million compared to 2024.
Positive Developments in Product Usage
Chromium reaction volumes showed robust year-over-year growth, and Xenium consumable revenue and volume continued to grow strongly.
Innovative Product Launches
Recent product launches, including GEM-X technology and Visium HD, continue to resonate with customers and advance the company's leadership in single-cell and spatial biology.
Negative Updates
Decline in Instrument Revenue
Total instrument revenue decreased by 42% year-over-year, with Chromium instrument revenue down 25% and spatial instrument revenue down 49%.
U.S. Academic and Government Funding Pressures
Significant uncertainty in U.S. academic and government research funding, leading to unpredictable customer purchasing behavior and reduced visibility on outlook.
Withdrawal of Full-Year Revenue Guidance
The company withdrew its full-year revenue guidance due to uncertainties in the funding environment, providing only Q2 guidance instead.
Challenges in EMEA Revenue
Revenue in the EMEA region decreased by 8%, attributed to challenging macroeconomic conditions affecting instrument sales.
Company Guidance
During the first quarter of 2025, 10x Genomics reported total revenue of $155 million, including a $26 million gain from a settlement with Vizgen. Excluding this, revenue was $138 million, down 2% year-over-year. Consumables revenue grew by 5% to $115.4 million, with spatial consumables up 18%, while instrument revenue declined by 42% to $14.8 million. The company cited a challenging macro environment, especially within U.S. academic and government funding, as a significant factor affecting revenue, leading to the withdrawal of its full-year guidance. Approximately 40-50% of 10x Genomics' revenue is exposed to these funding sources. Gross profit for the quarter was $105.4 million with a margin of 68%, and operating expenses decreased to $144.8 million. The company ended the quarter with $427 million in cash and securities. Due to uncertainties, 10x Genomics implemented cost-cutting measures, including an 8% workforce reduction, anticipating a $50 million reduction in operating expenses for 2025. For the second quarter, revenue is expected to be between $138 million and $142 million. Despite the challenges, the company remains confident in the long-term growth potential of its products and market position.

10x Genomics Corporate Events

Legal Proceedings
10x Genomics Settles Litigation with Bruker Corporation
Neutral
May 14, 2025

On May 12, 2025, 10x Genomics, Inc. reached a settlement and licensing agreement with Bruker Corporation, resolving all global litigation and proceedings between the parties. This agreement follows a series of lawsuits initiated by 10x Genomics against NanoString Technologies, Inc., which were inherited by Bruker after acquiring certain NanoString assets in May 2024, and is expected to lead to the dismissal of all claims within five days of the agreement date.

The most recent analyst rating on (TXG) stock is a Hold with a $20.00 price target. To see the full list of analyst forecasts on 10x Genomics stock, see the TXG Stock Forecast page.

Business Operations and StrategyFinancial Disclosures
10x Genomics Announces Workforce Reduction to Cut Costs
Negative
May 8, 2025

On May 6, 2025, 10x Genomics announced a reduction in its global workforce by approximately 8% to decrease costs and align with strategic priorities, estimating related expenses between $5.5 million and $6.5 million. The company reported first-quarter 2025 revenue of $154.9 million, a 10% increase from the previous year, driven by a patent litigation settlement. Despite a decrease in instrument revenue, 10x Genomics plans to reduce operating expenses by over $50 million in 2025 and has unveiled new product launches and a partnership with Arc Institute to enhance its market position.

Glossary
OutperformA stock rated as "Outperform" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests that the stock is likely to deliver higher returns compared to the average returns of other stocks in the same sector or market index. Investors might consider this stock a good buying opportunity.
NeutralA stock rated as "Neutral" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly attractive nor unattractive for investment. Investors may consider holding onto the stock, as it is not expected to either significantly outperform or underperform the market.
UnderperformA stock rated as "Underperform" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests that the stock may deliver lower returns compared to the average returns of other stocks in the same sector or market index. Investors might consider selling the stock or avoiding it as an investment.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.