Syndax Pharmaceuticals stock analysis
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Syndax Pharmaceuticals (SNDX) Stock Price & Analysis
SNDX Stock Chart & Stats
- Day’s Range
- $9.11 - $9.85
- 52-Week Range
- $9.11 - $25.59
- Previous Close
- $9.54
- Volume
- N/A
- Average Volume (3M)
- 3.51M
- Market Cap
- $858.87M
- Enterprise Value
- $1.85B
- Total Cash (Recent Filing)
- $427.10M
- Total Debt (Recent Filing)
- $589.41M
- Price to Earnings (P/E)
- ―
- Beta
- 1.20
- Next Earnings
- Mar 02, 2027 (Est.)
- EPS Estimate
- -0.53
- Next Dividend Ex-Date
- N/A
- Dividend Yield
- N/A
Bulls Say, Bears Say
Bulls Say
Commercial Growth And Market Leadership
Revuforj is showing sustained commercial adoption, with strong year-over-year growth, broad account penetration, and leadership in its menin-inhibitor class. This scale can reinforce prescribing momentum, support durable revenue expansion, and provide a foundation for future indications.
Growing Collaboration Contribution
Niktimvo provides an increasingly meaningful recurring contribution alongside Revuforj, while improving margin economics strengthen the quality of revenue. Continued penetration in chronic GVHD could support cash generation and reduce reliance on a single commercial product.
Funded Commercial And Pipeline Execution
The reported cash position supports continued investment in commercial expansion, front-line trials, and earlier pipeline assets over the next several quarters. Funding visibility gives management flexibility to pursue multiple catalysts without immediately curtailing development priorities.
Bears Say
Deep Ongoing Unprofitability
Syndax remains materially unprofitable despite revenue growth and high gross margin. Persistent operating losses limit internally generated capital, make the path to sustainable earnings dependent on further scale, and could constrain investment flexibility if commercialization takes longer.
Cash Burn And Financing Pressure
Large recurring cash outflows mean the company is not yet self-funding its operations and development programs. Even with improvement from earlier periods, continued burn can consume liquidity over time and increase the importance of revenue growth, cost control, or additional financing.
Elevated Leverage And Negative Equity
Higher debt combined with negative equity signals a weakened capital base and reduced financial flexibility. This structure can increase pressure on future cash flows, limit capacity to absorb setbacks, and make funding commercial or pipeline expansion more challenging.
Syndax Pharmaceuticals News
Syndax Updates Revumenib Study for Patients With Organ Impairment
Syndax Pharmaceuticals Inc. ($SNDX) announced an update on their ongoing clinical study. Study Overview: Syndax Pharmaceuticals is evaluating how the body processes revumenib in people with relapsed or treatment-resistant blood
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Syndax Pharmaceuticals Stock Smart Score
Company Description
Syndax Pharmaceuticals
Syndax Pharmaceuticals, Inc. operates as a clinical-stage biopharmaceutical firm focused on developing innovative therapies for cancer. Among its leading investigational products are SNDX-5613, currently undergoing Phase 1/2 clinical assessment, which targets the Menin-mixed lineage leukemia 1 protein interaction for treating MLL-rearranged (MLLr) and nucleophosmin 1 mutant acute myeloid leukemia (NPM1c AML). Another significant candidate is SNDX-6352, or axatilimab, a monoclonal antibody designed to block the colony stimulating factor 1 (CSF-1) receptor, intended for patients suffering from chronic graft versus host disease (cGVHD). The company is additionally progressing Entinostat. Syndax has also established strategic collaborations, including a research and development agreement with the National Cancer Institute, a clinical trial agreement with the Eastern Cooperative Oncology Group, and a license agreement with Kyowa Hakko Kirin Co., Ltd. Founded in 2005, Syndax Pharmaceuticals, Inc. maintains its corporate headquarters in Waltham, Massachusetts.
- Sector
- Healthcare
- Industry
- Biotechnology
- CEO
- Michael A. Metzger
- Employees
- 298
- Website
- www.syndax.com
- Address
- 730 Third Avenue, New York City, NY, 10017, US
Syndax Pharmaceuticals (SNDX) Earnings & Revenues
SNDX Company Deck
SNDX Earnings Call
Earnings Call SentimentPositive
The call was strongly positive, supported by 82% year-over-year total revenue growth, sustained double-digit Revuforj growth, expanding patient starts and account adoption, rising Niktimvo revenue and collaboration income, a strong cash position, and multiple clinical and pipeline catalysts. The principal challenges were the temporary transplant-related treatment pauses, prior-quarter market volatility, active competition and delayed timing for certain clinical readouts. Highlights significantly outweighed the lowlights.
View all SNDX earnings summariesSNDX Stock 12 Month Forecast
Average Price Target
Technical Analysis
Overall Consensus
| Indicator | Bullish | Neutral | Bearish |
|---|---|---|---|
| Overall Consensus | 5 | 3 | 14 |
| Technical Analysis | 5 | 3 | 2 |
| Moving Averages | 0 | 0 | 12 |














