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Simulations Plus (SLP)
NASDAQ:SLP
US Market
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Simulations Plus (SLP) AI Stock Analysis

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SLP

Simulations Plus

(NASDAQ:SLP)

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Neutral 65 (OpenAI - 5.2)
Rating:65Neutral
Price Target:
$18.50
▲(61.85% Upside)
Action:Reiterated
Date:05/31/26
The score is driven primarily by solid balance-sheet strength and strong cash generation, supported by bullish technical momentum. It is held back by the recent collapse in reported profitability (negative P/E) and management’s conservative outlook amid renewal and clinical-ops softness.
Positive Factors
Conservative balance sheet
Very low leverage and a debt-free capital structure materially reduce refinancing and solvency risk, providing durable financial flexibility to fund R&D, pursue partnerships, and weather cyclical industry downturns without pressuring cash flow or requiring dilutive financing.
Negative Factors
Sharp profitability deterioration
A large swing to substantial net losses and a collapse in return on equity signal earnings-quality and margin risk; if elevated operating costs or non-recurring charges persist, capital efficiency and capacity to reinvest from profits may remain impaired for multiple quarters.
Read all positive and negative factors
Positive Factors
Negative Factors
Conservative balance sheet
Very low leverage and a debt-free capital structure materially reduce refinancing and solvency risk, providing durable financial flexibility to fund R&D, pursue partnerships, and weather cyclical industry downturns without pressuring cash flow or requiring dilutive financing.
Read all positive factors

Simulations Plus Key Performance Indicators (KPIs)

Any
Any
Revenue by Geography
Revenue by Geography
Breaks down revenue across different regions, revealing where the company is strongest and where it may face risk or growth potential due to local economic conditions or market share shifts.
Chart InsightsAmericas is the clear revenue engine and explains most of SLP’s growth, while EMEA’s pattern looks lumpy—large, early‑year spikes consistent with timing of big deals—indicating revenue is driven by episodic enterprise contracts. APAC is smaller but steadily growing. Management’s rising software mix and an expanding services backlog support better margins and smoother future services revenue, but geographic concentration, softer renewal rates among smaller pharma customers and conservative guidance (plus a higher tax rate) mean near‑term top‑line and EPS upside may remain uneven.
Data provided by:The Fly

Simulations Plus (SLP) vs. SPDR S&P 500 ETF (SPY)

Simulations Plus Business Overview & Revenue Model

Company Description
Simulations Plus, Inc. develops drug discovery and development software for modeling and simulation, and prediction of molecular properties utilizing artificial intelligence and machine learning based technology worldwide. It operates through four...
How the Company Makes Money
Simulations Plus primarily makes money through (1) software revenue and (2) services revenue. Software revenue is generated by licensing and supporting its scientific modeling and simulation products (for example, GastroPlus and related modules), ...

Simulations Plus Earnings Call Summary

Earnings Call Date:Apr 09, 2026
(Q2-2026)
|
% Change Since: |
Next Earnings Date:Jul 08, 2026
Earnings Call Sentiment Positive
The call presented a generally positive operational and financial picture: revenue growth (+8% YoY), strong adjusted EBITDA and margin expansion, increased services backlog, high software gross margins, and a solid balance sheet with $41.8M in cash and no debt. Strategic partnerships with three large pharma customers and continued AI integration represent meaningful long-term upside. Offsetting these positives were a pronounced decline in clinical operations revenue (–54%), lower trailing renewal rates (87% TTM), a materially higher effective tax rate (now 23–25%) reducing EPS, reduced other income, and management's deliberately conservative guidance due to macro fragility and limited near-term AI monetization. Overall, the encouraging growth, margins, cash position and strategic progress materially outweigh the notable but contained operational and tax headwinds.
Positive Updates
Revenue Growth and Top-Line Beat
Total revenue of $24.3 million in Q2 (up 8% year-over-year). Management noted they exceeded the top-line guidance communicated last quarter.
Negative Updates
Sharp Decline in Clinical Operations Revenue
Clinical operations revenue (primarily from Proficiency) declined 54% in the quarter and 58% on a trailing 12-month basis, representing only ~3% of software revenue — a material weakness in that subsegment.
Read all updates
Q2-2026 Updates
Negative
Revenue Growth and Top-Line Beat
Total revenue of $24.3 million in Q2 (up 8% year-over-year). Management noted they exceeded the top-line guidance communicated last quarter.
Read all positive updates
Company Guidance
Management left fiscal 2026 guidance largely unchanged, forecasting total revenue of $79–82 million (0%–4% year‑over‑year growth), a software mix of 57%–62%, adjusted EBITDA margin of 26%–30% and adjusted diluted EPS of $0.75–0.85 (driven by a revised effective tax rate of 23%–25% versus the prior 12%–14% expectation); for Q3 they expect revenue of $20–22 million, adjusted EBITDA margin of 27%–33% and adjusted diluted EPS of $0.20–0.27 — the company also ended the quarter with $41.8 million in cash and short‑term investments, no debt, and a services backlog of $24.0 million (up 18% year‑over‑year).

Simulations Plus Financial Statement Overview

Summary
Mixed fundamentals: strong and improving operating/free cash flow plus an extremely low-leverage balance sheet, but reported profitability deteriorated sharply with very large recent net losses, creating elevated earnings-quality and margin-sustainability risk.
Income Statement
46
Neutral
Balance Sheet
78
Positive
Cash Flow
72
Positive
BreakdownTTMNov 2025Aug 2024Aug 2023Aug 2022Aug 2021
Income Statement
Total Revenue80.53M79.18M70.01M59.58M53.91M46.47M
Gross Profit49.91M46.22M43.15M47.95M43.08M35.87M
EBITDA16.82M14.70M11.80M13.06M18.69M14.70M
Net Income-62.79M-64.72M9.95M9.96M12.48M9.78M
Balance Sheet
Total Assets146.48M131.94M207.64M192.64M190.50M181.61M
Cash, Cash Equivalents and Short-Term Investments41.84M32.35M20.25M115.46M128.24M123.60M
Total Debt508.00K616.00K1.01M1.20M1.40M1.28M
Total Liabilities12.71M7.13M25.21M22.61M12.26M15.83M
Stockholders Equity133.77M124.80M182.43M170.03M178.25M165.78M
Cash Flow
Free Cash Flow23.77M17.41M12.75M17.58M13.93M14.63M
Operating Cash Flow24.38M18.13M13.32M21.86M17.90M19.20M
Investing Cash Flow-10.23M3.56M-53.97M7.37M4.30M-26.74M
Financing Cash Flow590.00K-1.15M-6.57M-23.27M-7.62M-4.68M

Simulations Plus Technical Analysis

Technical Analysis Sentiment
Positive
Last Price11.43
Price Trends
50DMA
14.31
Positive
100DMA
14.44
Positive
200DMA
15.58
Positive
Market Momentum
MACD
0.69
Negative
RSI
60.01
Neutral
STOCH
63.17
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For SLP, the sentiment is Positive. The current price of 11.43 is below the 20-day moving average (MA) of 15.32, below the 50-day MA of 14.31, and below the 200-day MA of 15.58, indicating a bullish trend. The MACD of 0.69 indicates Negative momentum. The RSI at 60.01 is Neutral, neither overbought nor oversold. The STOCH value of 63.17 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Positive sentiment for SLP.

Simulations Plus Risk Analysis

Simulations Plus disclosed 47 risk factors in its most recent earnings report. Simulations Plus reported the most risks in the "Finance & Corporate" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

Simulations Plus Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
79
Outperform
$738.85M37.225.67%0.52%6.64%6.54%
73
Outperform
$1.08B-167.70-2.81%49.36%83.76%
65
Neutral
$336.42M-5.10-49.30%2.51%-962.01%
63
Neutral
$872.72M-56.10-1.43%6.40%-477.58%
54
Neutral
$355.48M-4.39-140.63%20.85%-18.60%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
48
Neutral
$492.67M-0.95-77.89%-21.26%-290.08%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
SLP
Simulations Plus
15.88
-11.67
-42.36%
HSTM
HealthStream
25.24
-3.13
-11.04%
EVH
Evolent Health
4.22
-4.11
-49.34%
CERT
Certara
5.37
-6.39
-54.34%
SOPH
SOPHiA GENETICS
5.00
1.87
59.74%
OMDA
Omada Health, Inc.
17.93
-4.67
-20.66%

Simulations Plus Corporate Events

Business Operations and StrategyFinancial Disclosures
Simulations Plus Reports Q2 2026 Results, Trims EPS Outlook
Neutral
Apr 9, 2026
On April 9, 2026, Simulations Plus reported second‑quarter fiscal 2026 results for the period ended February 28, 2026, with total revenue up 8% year on year to $24.3 million and broad-based growth in both software and services. Software sale...
Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: May 31, 2026