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Fate Therapeutics (FATE)
NASDAQ:FATE
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Fate Therapeutics (FATE) AI Stock Analysis

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FATE

Fate Therapeutics

(NASDAQ:FATE)

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Neutral 48 (OpenAI - 4o)
Rating:48Neutral
Price Target:
$1.50
▲(7.91% Upside)
Fate Therapeutics' overall stock score is primarily impacted by its challenging financial performance, characterized by persistent losses and negative cash flow. While technical indicators suggest short-term bullish momentum, the negative valuation metrics due to ongoing losses and lack of dividends weigh heavily on the stock's attractiveness. Investors should be cautious and consider the risks associated with the company's financial instability.
Positive Factors
Innovative Technology
The company's proprietary iPSC technology positions it at the forefront of cellular immunotherapy, offering a competitive edge in developing transformative cancer treatments.
Strategic Partnerships
Strategic alliances provide financial support and potential market access, crucial for advancing clinical programs and achieving commercialization.
Low Debt Levels
Low debt levels enhance financial flexibility, allowing the company to focus on R&D without the burden of high interest obligations.
Negative Factors
Negative Cash Flow
Persistent negative cash flow indicates reliance on external funding, which could limit operational flexibility and increase financial risk.
Declining Revenue
Significant revenue decline suggests challenges in product commercialization and market penetration, impacting long-term growth prospects.
Persistent Losses
Ongoing losses highlight operational inefficiencies and the need for strategic changes to achieve profitability and sustainable growth.

Fate Therapeutics (FATE) vs. SPDR S&P 500 ETF (SPY)

Fate Therapeutics Business Overview & Revenue Model

Company DescriptionFate Therapeutics, Inc., a clinical-stage biopharmaceutical company, develops programmed cellular immunotherapies for cancer and immune disorders worldwide. Its NK- and T-cell immuno-oncology programs under development include FT516 for the treatment of acute myeloid leukemia (AML) B-cell lymphoma, and advanced solid tumor; FT596 to treat B-cell lymphoma and chronic lymphocytic leukemia; FT538 to treat AML and multiple myeloma; FT576 to treat multiple myeloma; FT819 to treat hematologic malignancies and solid tumors; FT536 to treat solid tumors; and FT500 for the treatment of advanced solid tumors. The company has a collaboration and option agreement with Ono Pharmaceutical Co. Ltd. for the development and commercialization of two off-the-shelf iPSC-derived CAR T-cell product candidates; strategic research collaboration and license agreement with Juno Therapeutics, Inc. to screen for and identify small molecule modulators that enhance the therapeutic properties of genetically-engineered T-cell immunotherapies; and a collaboration and option agreement with Janssen Biotech, Inc. Fate Therapeutics, Inc. was incorporated in 2007 and is headquartered in San Diego, California.
How the Company Makes MoneyFate Therapeutics generates revenue primarily through the development of its therapeutic candidates, which are funded by collaborations and partnerships with larger pharmaceutical companies. The company engages in strategic alliances that provide upfront payments, milestone payments tied to clinical progress, and royalties on future sales of products developed using its technology. Additionally, Fate Therapeutics may receive funding through government grants and research contracts. Its revenue model is heavily reliant on successful research and development outcomes, regulatory approvals for its therapies, and the commercialization of its products in collaboration with partners.

Fate Therapeutics Earnings Call Summary

Earnings Call Date:Aug 12, 2025
(Q1-2024)
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% Change Since: |
Next Earnings Date:Oct 30, 2025
Earnings Call Sentiment Neutral
The earnings call highlighted significant progress in clinical trials, particularly with FT819 and FT522, alongside a strong financial position. However, revenue growth remains limited and operating expenses are high, suggesting a balanced outlook with promising clinical achievements countered by financial challenges.
Q1-2024 Updates
Positive Updates
FT819 and FT522 Data Presentation
Presented promising data from FT819 and FT522 programs at the ASGCT Annual Meeting, showing potential disease-modifying effects and immune reset in B-cell-mediated autoimmune diseases.
First Lupus Patient Treated
The first lupus patient was treated with FT819, showing no notable adverse events post-treatment.
Strong Financial Position and Fundraising
Raised $100 million through an underwritten offering and a private placement, ending the quarter with $391 million in cash, cash equivalents, and investments.
FT522 Safety Assessment
First 3 patients in FT522 study completed safety assessment without dose-limiting toxicities.
Negative Updates
Limited Revenue Growth
Reported revenue of $1.9 million, consistent with prior quarters, reflecting limited growth.
High Operating Expenses
Total operating expenses for the quarter increased by 7% relative to the fourth quarter of 2023 to $53 million.
Company Guidance
During the Fate Therapeutics Q1 2024 earnings call, the company provided guidance on its clinical and financial outlook. Key program initiatives were discussed, including the FT819 CAR T-cell and FT522 CAR NK cell programs, with notable translational data presented at the American Society of Gene and Cell Therapy Annual Meeting. The company highlighted its plans to achieve several clinical milestones across its iPSC product pipeline, targeting both cancer and autoimmune diseases. Financially, Fate Therapeutics raised $100 million through an underwritten offering and private placement, ending the first quarter with approximately $391 million in cash. Operating expenses for the full year are projected between $215 million and $230 million, with a year-end cash balance exceeding $270 million. The company's strategic focus is on demonstrating the disease-modifying potential of its therapies while maintaining a strong financial position to support ongoing and future clinical development.

Fate Therapeutics Financial Statement Overview

Summary
Fate Therapeutics faces substantial financial challenges, with persistent losses and negative cash flow raising concerns about its operational sustainability. The company has a negative gross profit margin and deeply negative net profit margins. The balance sheet shows a manageable debt-to-equity ratio but a declining equity base, raising sustainability concerns.
Income Statement
40
Negative
Fate Therapeutics has faced significant challenges in its income statement metrics. The company experienced a significant decline in total revenue from 2020 to 2024, with a revenue growth rate of -78.54% from 2023 to 2024. The gross profit margin has been negative for several years, indicating high costs relative to revenues. Net profit margins are also deeply negative, reflecting persistent losses. EBIT and EBITDA margins are similarly negative, demonstrating the company’s struggle to cover its operating costs and generate positive earnings.
Balance Sheet
50
Neutral
The balance sheet reveals a mixed picture. The debt-to-equity ratio has remained reasonably low, suggesting manageable leverage levels. However, the return on equity is negative due to consistent net losses, indicating a lack of profitability. The equity ratio is relatively high at 72.31% in 2024, showcasing financial stability and reliance on equity financing. Still, the equity base has shrunk over the years, raising concerns over long-term sustainability.
Cash Flow
45
Neutral
Cash flow metrics highlight the company’s ongoing cash challenges. Free cash flow remains negative, though there was a small improvement in 2024. The operating cash flow to net income ratio is negative, indicating operational cash flow deficits. The free cash flow to net income ratio also remains negative, underlining the company's struggle to generate sufficient cash to cover its expenditures without external financing.
BreakdownTTMDec 2024Dec 2023Dec 2022Dec 2021Dec 2020
Income Statement
Total Revenue8.47M13.63M63.53M96.30M55.85M31.43M
Gross Profit5.19M13.63M-93.65M82.54M50.00M-94.19M
EBITDA-164.88M-176.58M-172.23M-294.63M-211.14M-125.00M
Net Income-171.52M-186.26M-160.93M-281.72M-212.15M-173.39M
Balance Sheet
Total Assets371.63M440.69M506.22M705.56M921.46M622.46M
Cash, Cash Equivalents and Short-Term Investments222.83M279.07M315.18M436.23M615.91M482.92M
Total Debt81.33M85.27M103.54M109.34M114.82M97.30M
Total Liabilities110.27M121.97M137.80M221.62M242.62M238.01M
Stockholders Equity261.36M318.73M368.42M483.94M678.84M384.44M
Cash Flow
Free Cash Flow-118.77M-123.60M-138.42M-283.77M-213.57M-44.16M
Operating Cash Flow-115.61M-122.87M-132.26M-248.21M-162.87M-39.23M
Investing Cash Flow110.54M12.22M112.67M166.75M-324.02M-161.08M
Financing Cash Flow4.46M99.89M85.00K9.21M453.13M282.84M

Fate Therapeutics Technical Analysis

Technical Analysis Sentiment
Positive
Last Price1.39
Price Trends
50DMA
1.07
Positive
100DMA
1.15
Positive
200DMA
1.18
Positive
Market Momentum
MACD
0.07
Negative
RSI
70.92
Negative
STOCH
79.41
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For FATE, the sentiment is Positive. The current price of 1.39 is above the 20-day moving average (MA) of 1.07, above the 50-day MA of 1.07, and above the 200-day MA of 1.18, indicating a bullish trend. The MACD of 0.07 indicates Negative momentum. The RSI at 70.92 is Negative, neither overbought nor oversold. The STOCH value of 79.41 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Positive sentiment for FATE.

Fate Therapeutics Risk Analysis

Fate Therapeutics disclosed 86 risk factors in its most recent earnings report. Fate Therapeutics reported the most risks in the "Tech & Innovation" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

Fate Therapeutics Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
56
Neutral
$167.43M87.50-35.66%-48.16%-97.37%
55
Neutral
$163.56M-73.39%-27.33%34.66%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
48
Neutral
$162.61M-52.11%-31.23%14.92%
47
Neutral
$146.36M-91.93%-17.89%3.93%
43
Neutral
39
Underperform
$152.70M-26.94%26.33%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
FATE
Fate Therapeutics
1.39
-1.62
-53.82%
CGEN
Compugen
1.76
0.02
1.15%
ONCY
Oncolytics Biotech
1.35
0.04
3.05%
TSE:ONC
Oncolytics Biotech
1.42
-0.39
-21.55%
CRDF
Cardiff Oncology
2.24
-0.28
-11.11%
NKTX
Nkarta
2.06
-1.88
-47.72%
STTK
Shattuck Labs
2.45
1.05
75.00%

Fate Therapeutics Corporate Events

Business Operations and StrategyFinancial Disclosures
Fate Therapeutics Announces Corporate Restructuring Plan
Neutral
Aug 12, 2025

On August 7, 2025, Fate Therapeutics‘ Board of Directors approved a corporate restructuring to streamline operations, reduce expenses, and extend its cash runway, which includes a 12% reduction in workforce. The restructuring is expected to incur charges of $0.9 million to $1.2 million for severance and related costs in the third quarter of 2025. Additionally, the company reported significant progress in its clinical programs, particularly with its FT819 CAR T-cell product for autoimmune diseases, and plans to expand its trials to include other B cell-mediated autoimmune diseases. Fate Therapeutics is also advancing its pipeline with collaborations and new technologies, aiming to optimize resource allocation and extend its cash runway through the end of 2027.

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Oct 07, 2025