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Shattuck Labs, Inc. (STTK)
NASDAQ:STTK
US Market
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Shattuck Labs (STTK) AI Stock Analysis

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STTK

Shattuck Labs

(NASDAQ:STTK)

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Neutral 53 (OpenAI - 5.2)
Rating:53Neutral
Price Target:
$7.00
▼(-7.04% Downside)
Action:Reiterated
Date:07/16/26
The score is held back primarily by weak financial performance (large losses and ongoing cash burn on very low revenue), partially offset by a strong low-debt balance sheet. Technical indicators are supportive (price above key moving averages with positive MACD), and recent corporate updates add pipeline momentum and funding support, though dilution from the offering and loss-making status keep valuation and fundamentals pressured.
Positive Factors
Clinical Progress (SL-325)
Robust Phase 1 human data materially lowers clinical risk for SL-325 by demonstrating target engagement, durability and a clean safety signal. That increases probability of success in the planned Phase 2b Crohn’s trial, supports downstream partnering/licensing discussions, and strengthens long-term asset potential for the inflammatory franchise.
Negative Factors
Sustained Cash Burn
Persistent negative operating and free cash flow indicates ongoing reliance on external financing to sustain clinical development. While burn has improved versus prior years, the company remains far from cash-flow break-even, which creates execution risk if capital markets tighten or expected financings underperform.
Read all positive and negative factors
Positive Factors
Negative Factors
Clinical Progress (SL-325)
Robust Phase 1 human data materially lowers clinical risk for SL-325 by demonstrating target engagement, durability and a clean safety signal. That increases probability of success in the planned Phase 2b Crohn’s trial, supports downstream partnering/licensing discussions, and strengthens long-term asset potential for the inflammatory franchise.
Read all positive factors

Shattuck Labs (STTK) vs. SPDR S&P 500 ETF (SPY)

Shattuck Labs Business Overview & Revenue Model

Company Description
Shattuck Labs, Inc. operates as a biotechnology firm based in the United States, currently at the clinical development stage. Its core mission is to create innovative therapeutics designed to combat both cancer and autoimmune diseases. The company...
How the Company Makes Money
Shattuck Labs does not primarily generate revenue from product sales because its candidates are in clinical development and, to the extent publicly disclosed, it has not commercialized an approved therapy. The company’s revenue, when present, is g...

Shattuck Labs Financial Statement Overview

Summary
Overall fundamentals are weak: minimal TTM revenue (~$1.0M) against large TTM net losses (~-$49.9M) and significant cash burn (TTM operating/free cash flow ~-$41.3M). The balance sheet is a relative positive with very low leverage (debt-to-equity ~0.02; total debt ~$2.0M) and sizable equity (~$95.8M), but equity has been trending down due to ongoing losses.
Income Statement
18
Very Negative
Balance Sheet
62
Positive
Cash Flow
24
Negative
BreakdownTTMDec 2025Dec 2024Dec 2023Dec 2022Dec 2021
Income Statement
Total Revenue1.00M1.00M5.72M1.66M652.00K30.02M
Gross Profit-8.44M-1.95M827.00K-2.38M-81.55M28.64M
EBITDA-46.23M-45.12M-71.58M-83.26M-98.87M-43.59M
Net Income-49.87M-48.81M-75.41M-87.30M-101.94M-44.97M
Balance Sheet
Total Assets102.12M91.03M91.05M159.56M205.32M298.58M
Cash, Cash Equivalents and Short-Term Investments90.42M78.06M72.99M130.63M161.28M268.80M
Total Debt2.89M2.42M3.41M4.20M4.90M0.00
Total Liabilities6.29M8.64M11.42M14.86M29.17M26.80M
Stockholders Equity95.83M82.39M79.63M144.71M176.16M271.79M
Cash Flow
Free Cash Flow-41.28M-39.95M-60.57M-81.64M-106.11M-65.04M
Operating Cash Flow-41.27M-39.88M-60.52M-81.23M-94.50M-57.12M
Investing Cash Flow361.00K-7.89M-8.51M110.86M49.44M-10.44M
Financing Cash Flow70.43M44.57M787.00K48.62M171.00K1.93M

Shattuck Labs Technical Analysis

Technical Analysis Sentiment
Positive
Last Price7.53
Price Trends
50DMA
5.95
Positive
100DMA
6.13
Positive
200DMA
4.57
Positive
Market Momentum
MACD
0.38
Negative
RSI
64.63
Neutral
STOCH
68.24
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For STTK, the sentiment is Positive. The current price of 7.53 is above the 20-day moving average (MA) of 6.52, above the 50-day MA of 5.95, and above the 200-day MA of 4.57, indicating a bullish trend. The MACD of 0.38 indicates Negative momentum. The RSI at 64.63 is Neutral, neither overbought nor oversold. The STOCH value of 68.24 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Positive sentiment for STTK.

Shattuck Labs Risk Analysis

Shattuck Labs disclosed 56 risk factors in its most recent earnings report. Shattuck Labs reported the most risks in the "Tech & Innovation" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

Shattuck Labs Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
56
Neutral
$102.48M-2.81-241.96%55.59%
53
Neutral
$680.50M-11.95-60.73%-78.29%54.16%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
48
Neutral
$74.90M-0.88-64.43%9.80%
47
Neutral
$58.39M-1.61-117.24%476.71%70.23%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
STTK
Shattuck Labs
7.53
6.76
877.92%
PYPD
PolyPid
5.37
1.62
43.20%
XLO
Xilio Therapeutics
8.88
-0.88
-9.05%
ACRV
Acrivon Therapeutics, Inc.
1.75
0.35
25.00%

Shattuck Labs Corporate Events

Business Operations and StrategyPrivate Placements and Financing
Shattuck Labs Prices Upsized Public Equity and Warrant Offering
Positive
Jun 11, 2026
On June 9, 2026, Shattuck Labs, Inc. entered into an underwriting agreement with a syndicate of investment banks for a public offering of 10,879,376 common shares at $4.00 each and pre-funded warrants for 7,870,624 common shares at $3.9999 each. T...
Business Operations and StrategyPrivate Placements and FinancingProduct-Related Announcements
Shattuck Labs Reports Promising Phase 1 Data for SL-325
Positive
Jun 9, 2026
On June 8, 2026, Shattuck Labs reported Phase 1 data for SL-325, the first DR3 receptor-blocking antibody to generate human clinical results, showing low immunogenicity, durable TL1A blockade exceeding 10 weeks, complete DR3 occupancy at low doses...
Executive/Board ChangesShareholder Meetings
Shattuck Labs Shareholders Approve Directors, Compensation, Governance Measures
Positive
Jun 2, 2026
At its recent Annual Meeting, Shattuck Labs’ shareholders elected all Class III director nominees, including Taylor Schreiber, M.D., Ph.D., Helen M. Boudreau and Clay Siegall, Ph.D., and approved all other proposals, including the ratificati...
Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Jul 16, 2026