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Shattuck Labs (STTK)
NASDAQ:STTK
Sl-325
Healthy Volunteers
Phase I
Recruiting
Phase 1 Study of SL-325 in Healthy Volunteers
Aug 28, 2025
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Pegylated Liposomal Doxorubicin + Sl-172154, Mirvetuximab + Sl-172154
Epithelial Ovarian Cancer, Fallopian Tube Cancer, Primary Peritoneal Carcinoma, Ovarian Cancer, Platinum-Resistant Fallopian Tube Carcinoma, Platinum-Resistant Primary Peritoneal Carcinoma, Platinum-Resistant Ovarian Cancer
Phase I
Completed
Phase 1b Study of SL-172154 Administered with Combination Agent(s) in Subjects with Ovarian Cancers
Jul 26, 2022
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Venetoclax, Sl-172154, Azacitidine (Aza)
Acute Myeloid Leukemia, Myelodysplastic Syndromes
Phase I
Completed
Phase 1 Study of Shattuck Labs (SL)-172154 in Subjects With MDS or AML
Feb 15, 2022
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Drug: Sl-172154
Cutaneous Squamous Cell Carcinoma, Squamous Cell Carcinoma Of Head And Neck
Phase I
Terminated
Ph1 Study of SL-172154 Administered Intratumorally in Subjects With Squamous Cell Carcinoma of the Head and Neck or Skin
Jul 31, 2020
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Sl-172154
Fallopian Tube Cancer, Primary Peritoneal Carcinoma, Ovarian Cancer
Phase I
Completed
Phase 1 Study of SL-172154 (SIRPα-Fc-CD40L) in Subjects With Ovarian Cancer
May 19, 2020
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Sl-279252
Melanoma, Urothelial Carcinoma, Non Small Cell Lung Cancer, Renal Cell Carcinoma, Diffuse Large B Cell Lymphoma, Gastric Adenocarcinoma, Gastroesophageal Junction Adenocarcinoma, Hodgkin Lymphoma, Squamous Cell Carcinoma Of The Head And Neck, Squamous Cell Carcinoma Of The Anus, Squamous Cell Carcinoma Of The Cervix, Squamous Cell Carcinoma Of The Skin, Mismatch Repair Deficient Or Msi-High Solid Tumors
Phase I
Completed
SL-279252 (PD1-Fc-OX40L) in Subjects With Advanced Solid Tumors or Lymphomas
Jan 10, 2019
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FAQ
What are the FDA phases for drug approval?
The FDA approval process for new drugs is divided into several phases:
a. Preclinical testing
b. Phase 1 – Safety and dosage
c. Phase 2 – Effectiveness and side effects
d. Phase 3 – Confirmation of effectiveness, monitoring of adverse reactions, and comparison with existing treatments
e. Phase 4 – Post-marketing studies to track long-term safety and effectiveness
a. Preclinical testing
b. Phase 1 – Safety and dosage
c. Phase 2 – Effectiveness and side effects
d. Phase 3 – Confirmation of effectiveness, monitoring of adverse reactions, and comparison with existing treatments
e. Phase 4 – Post-marketing studies to track long-term safety and effectiveness
What is a clinical trial?
A clinical trial is a carefully designed study in which researchers test a drug, treatment, or medical device in people to evaluate its safety, effectiveness, and potential side effects. These trials are essential for determining whether a new treatment should be approved for widespread use.
What drugs does Shattuck Labs (STTK) have in its pipeline
STTK is currently developing the following drugs: Sl-325, Pegylated Liposomal Doxorubicin + Sl-172154, Mirvetuximab + Sl-172154, Venetoclax, Sl-172154, Azacitidine (Aza). These drug candidates are in various stages of clinical development as the company works toward FDA approval.