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Coya Therapeutics, Inc. (COYA)
NASDAQ:COYA
US Market
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Coya Therapeutics, Inc. (COYA) AI Stock Analysis

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COYA

Coya Therapeutics, Inc.

(NASDAQ:COYA)

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Neutral 52 (OpenAI - 5.2)
Rating:52Neutral
Price Target:
$5.50
▲(15.06% Upside)
Action:Reiterated
Date:06/23/26
The score is primarily held back by weak financial performance driven by large losses and ongoing cash burn, despite improving revenue and low recent leverage. Technical indicators are moderately supportive and provide the main offset, while valuation remains challenged due to lack of profitability and no dividend support.
Positive Factors
Clinical Progress and Data Accrual
Initiating a blinded extension that extends patient exposure to COYA 302 to 48 weeks materially improves the company’s ability to generate longer-term efficacy and safety data. This reduces clinical uncertainty, strengthens future regulatory submissions, and supports durable evidence generation versus short trials.
Negative Factors
Persistent Negative Cash Flow
Consistent negative operating and free cash flow indicate the business is not self-sustaining and will require external funding until commercialization. Persistent cash burn constrains runway, forces financing timing decisions, and can pressure R&D continuity if capital markets tighten.
Read all positive and negative factors
Positive Factors
Negative Factors
Clinical Progress and Data Accrual
Initiating a blinded extension that extends patient exposure to COYA 302 to 48 weeks materially improves the company’s ability to generate longer-term efficacy and safety data. This reduces clinical uncertainty, strengthens future regulatory submissions, and supports durable evidence generation versus short trials.
Read all positive factors

Coya Therapeutics, Inc. (COYA) vs. SPDR S&P 500 ETF (SPY)

Coya Therapeutics, Inc. Business Overview & Revenue Model

Company Description
Coya Therapeutics, Inc. is a clinical-stage biotechnology company focused on developing innovative therapeutic agents that fine-tune the function of regulatory T cells (Tregs). Its therapeutic pipeline leverages diverse approaches, including biolo...
How the Company Makes Money
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Coya Therapeutics, Inc. Financial Statement Overview

Summary
Revenue is accelerating, but profitability remains extremely weak with deep net losses and persistent negative margins. Cash flow is still meaningfully negative (ongoing cash burn), partially offset by a more conservative balance sheet with minimal/zero debt in recent periods.
Income Statement
18
Very Negative
Balance Sheet
66
Positive
Cash Flow
32
Negative
BreakdownTTMDec 2025Dec 2024Dec 2023Dec 2022Dec 2021
Income Statement
Total Revenue7.94M7.95M3.55M6.00M0.000.00
Gross Profit7.92M7.92M-8.31M500.68K-4.41M0.00
EBITDA-21.10M-21.20M-17.20M-7.33M-9.26M-4.88M
Net Income-21.13M-21.23M-14.88M-7.99M-12.24M-4.89M
Balance Sheet
Total Assets53.27M49.95M44.35M41.26M8.40M4.79M
Cash, Cash Equivalents and Short-Term Investments50.72M46.82M38.34M32.63M5.93M4.34M
Total Debt0.000.000.000.0012.97M0.00
Total Liabilities4.30M6.92M4.77M5.63M16.79M1.15M
Stockholders Equity48.97M43.03M39.58M35.64M-8.39M3.64M
Cash Flow
Free Cash Flow-14.12M-10.74M-10.29M-11.19M-7.24M-4.04M
Operating Cash Flow-14.12M-10.74M-10.29M-11.19M-7.24M-3.90M
Investing Cash Flow-2.05M-1.16M-25.00K-543.19K-525.00K-136.80K
Financing Cash Flow31.36M20.39M16.03M38.43M9.36M-340.58K

Coya Therapeutics, Inc. Technical Analysis

Technical Analysis Sentiment
Positive
Last Price4.78
Price Trends
50DMA
4.58
Positive
100DMA
4.57
Positive
200DMA
5.19
Positive
Market Momentum
MACD
0.12
Negative
RSI
63.32
Neutral
STOCH
77.18
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For COYA, the sentiment is Positive. The current price of 4.78 is above the 20-day moving average (MA) of 4.76, above the 50-day MA of 4.58, and below the 200-day MA of 5.19, indicating a bullish trend. The MACD of 0.12 indicates Negative momentum. The RSI at 63.32 is Neutral, neither overbought nor oversold. The STOCH value of 77.18 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Positive sentiment for COYA.

Coya Therapeutics, Inc. Risk Analysis

Coya Therapeutics, Inc. disclosed 80 risk factors in its most recent earnings report. Coya Therapeutics, Inc. reported the most risks in the "Tech & Innovation" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

Coya Therapeutics, Inc. Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
57
Neutral
$127.96M8.1935.58%93.50%
52
Neutral
$124.09M-4.60-57.26%115.44%-1.14%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
47
Neutral
$91.32M-0.65-666.47%-100.00%46.40%
45
Neutral
$199.61M-2.08-30.90%10.70%
45
Neutral
$473.55M-8.32-60.73%-78.29%54.16%
42
Neutral
$75.30M-1.03-318.08%20.55%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
COYA
Coya Therapeutics, Inc.
5.29
-0.51
-8.79%
INO
Inovio Pharmaceuticals
1.11
-0.82
-42.49%
SPRO
Spero Therapeutics
2.21
-0.72
-24.57%
ANVS
Annovis Bio
1.77
-0.87
-32.95%
NKTX
Nkarta
2.79
1.05
60.34%
STTK
Shattuck Labs
5.24
4.23
418.81%

Coya Therapeutics, Inc. Corporate Events

Business Operations and StrategyPrivate Placements and Financing
Coya Therapeutics Establishes $30 Million ATM Equity Program
Neutral
May 12, 2026
On May 12, 2026, Coya Therapeutics, Inc. entered into a Sales Agreement with Leerink Partners LLC that allows the company to offer and sell up to $30 million of its common stock through at-the-market offerings on the Nasdaq Capital Market. The sha...
Business Operations and StrategyFinancial DisclosuresPrivate Placements and FinancingProduct-Related AnnouncementsRegulatory Filings and Compliance
Coya Therapeutics Updates Q1 Results, COYA 302 Progress
Positive
May 12, 2026
On May 12, 2026, Coya Therapeutics reported first-quarter 2026 results and a corporate update, highlighting U.S. FDA Fast Track Designation granted on March 11, 2026 for its ALS candidate COYA 302 and FDA acceptance of an IND for COYA 302 in front...
Business Operations and StrategyExecutive/Board Changes
Coya Therapeutics Announces Leadership Changes and New Director
Neutral
Apr 2, 2026
Coya Therapeutics, Inc. is a Houston-based, clinical-stage biotechnology company focused on developing proprietary treatments that leverage regulatory T cells to address systemic inflammation and neuroinflammation. Its pipeline includes Treg-enhan...
Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Jun 23, 2026