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Coya Therapeutics, Inc. (COYA)
NASDAQ:COYA
US Market
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Coya Therapeutics, Inc. (COYA) AI Stock Analysis

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COYA

Coya Therapeutics, Inc.

(NASDAQ:COYA)

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Neutral 47 (OpenAI - 5.2)
Rating:47Neutral
Price Target:
$4.50
▼(-10.71% Downside)
Action:Reiterated
Date:08/11/26
The score is held down primarily by extremely weak profitability and heavy cash burn, which outweigh the benefit of a debt-free balance sheet. Technicals are mixed-to-soft (negative MACD and below key longer-term averages), while valuation is constrained by losses and no dividend support. Regulatory progress and governance/financing events provide some offset but are not enough to materially lift the overall risk profile.
Positive Factors
Debt-free balance sheet
Zero reported debt materially reduces financing-related default and interest risk, preserving strategic optionality. For a clinical-stage biotech, this lowers fixed obligations and helps management prioritize R&D and partnership deals over debt servicing, supporting multi-quarter program execution.
Negative Factors
Very large cash burn
Sustained, very large negative operating cash flow creates continuous funding pressure and shortens runway absent material cost cuts or new financing. For a clinical-stage firm, this forces reliance on external capital and can constrain strategic options and program pacing over the next several quarters.
Read all positive and negative factors
Positive Factors
Negative Factors
Debt-free balance sheet
Zero reported debt materially reduces financing-related default and interest risk, preserving strategic optionality. For a clinical-stage biotech, this lowers fixed obligations and helps management prioritize R&D and partnership deals over debt servicing, supporting multi-quarter program execution.
Read all positive factors

Coya Therapeutics, Inc. (COYA) vs. SPDR S&P 500 ETF (SPY)

Coya Therapeutics, Inc. Business Overview & Revenue Model

Company Description
Coya Therapeutics, Inc. is a clinical-stage biotechnology company focused on developing innovative therapeutic agents that fine-tune the function of regulatory T cells (Tregs). Its therapeutic pipeline leverages diverse approaches, including biolo...
How the Company Makes Money
COYA is a clinical-stage biotechnology company and, based on publicly available information, does not primarily rely on product sales from approved therapies to generate revenue. Instead, the company’s revenue model is generally tied to (i) collab...

Coya Therapeutics, Inc. Financial Statement Overview

Summary
Financial profile is dominated by very large operating losses and sustained negative operating/free cash flow (TTM operating cash flow about -$13.6B), indicating meaningful funding dependence. The balance sheet is helped by zero reported debt, but profitability and cash generation remain extremely weak despite reported revenue growth.
Income Statement
18
Very Negative
Balance Sheet
62
Positive
Cash Flow
22
Negative
BreakdownTTMDec 2025Dec 2024Dec 2023Dec 2022Dec 2021
Income Statement
Total Revenue8.02M7.95M3.55M6.00M0.000.00
Gross Profit8.01M7.92M-8.31M500.68K-4.41M0.00
EBITDA-22.07M-21.20M-17.20M-7.33M-9.26M-4.88M
Net Income-21.67M-21.23M-14.88M-7.99M-12.24M-4.89M
Balance Sheet
Total Assets47.31B49.95M44.35M41.26M8.40M4.79M
Cash, Cash Equivalents and Short-Term Investments43.18B46.82M38.34M32.63M5.93M4.34M
Total Debt0.000.000.000.0012.97M0.00
Total Liabilities4.03B6.92M4.77M5.63M16.79M1.15M
Stockholders Equity43.28B43.03M39.58M35.64M-8.39M3.64M
Cash Flow
Free Cash Flow-13.68B-10.74M-10.29M-11.19M-7.24M-4.04M
Operating Cash Flow-13.68B-10.74M-10.29M-11.19M-7.24M-3.90M
Investing Cash Flow-887.82M-1.16M-25.00K-543.19K-525.00K-136.80K
Financing Cash Flow21.79B20.39M16.03M38.43M9.36M-340.58K

Coya Therapeutics, Inc. Technical Analysis

Technical Analysis Sentiment
Positive
Last Price5.04
Price Trends
50DMA
4.88
Negative
100DMA
4.70
Positive
200DMA
4.91
Negative
Market Momentum
MACD
0.07
Negative
RSI
53.42
Neutral
STOCH
57.28
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For COYA, the sentiment is Positive. The current price of 5.04 is above the 20-day moving average (MA) of 4.70, above the 50-day MA of 4.88, and above the 200-day MA of 4.91, indicating a neutral trend. The MACD of 0.07 indicates Negative momentum. The RSI at 53.42 is Neutral, neither overbought nor oversold. The STOCH value of 57.28 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Positive sentiment for COYA.

Coya Therapeutics, Inc. Risk Analysis

Coya Therapeutics, Inc. disclosed 79 risk factors in its most recent earnings report. Coya Therapeutics, Inc. reported the most risks in the "Tech & Innovation" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

Coya Therapeutics, Inc. Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
64
Neutral
$71.05M8.6416.17%26.04%
53
Neutral
$792.87M-15.00-43.57%-66.63%57.89%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
49
Neutral
$134.42M-1.08-1005.80%-100.00%54.89%
47
Neutral
$114.24M-4.54-0.20%1793.76%19.33%
45
Neutral
$75.84M-1.01-685.96%11.96%
44
Neutral
$188.37M-1.75-39.64%-6.70%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
COYA
Coya Therapeutics, Inc.
4.86
-1.85
-27.57%
INO
Inovio Pharmaceuticals
1.26
-1.20
-48.78%
SPRO
Spero Therapeutics
1.21
-0.79
-39.50%
ANVS
Annovis Bio
1.81
-0.51
-21.98%
NKTX
Nkarta
2.75
0.55
25.00%
STTK
Shattuck Labs
7.65
6.66
672.73%

Coya Therapeutics, Inc. Corporate Events

Executive/Board ChangesShareholder Meetings
Coya Therapeutics Shareholders Back Board, Auditor at Meeting
Positive
Jun 25, 2026
On June 25, 2026, Coya Therapeutics, Inc. held its Annual Meeting of Stockholders, where shareholders voted on the election of two Class I directors and the ratification of the company’s independent auditor for the 2026 fiscal year. Former U...
Business Operations and StrategyPrivate Placements and Financing
Coya Therapeutics Establishes $30 Million ATM Equity Program
Neutral
May 12, 2026
On May 12, 2026, Coya Therapeutics, Inc. entered into a Sales Agreement with Leerink Partners LLC that allows the company to offer and sell up to $30 million of its common stock through at-the-market offerings on the Nasdaq Capital Market. The sha...
Business Operations and StrategyFinancial DisclosuresPrivate Placements and FinancingProduct-Related AnnouncementsRegulatory Filings and Compliance
Coya Therapeutics Updates Q1 Results, COYA 302 Progress
Positive
May 12, 2026
On May 12, 2026, Coya Therapeutics reported first-quarter 2026 results and a corporate update, highlighting U.S. FDA Fast Track Designation granted on March 11, 2026 for its ALS candidate COYA 302 and FDA acceptance of an IND for COYA 302 in front...
Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Aug 11, 2026