Annovis Bio Inc (ANVS)
NYSE:ANVS
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Annovis Bio
(NYSE:ANVS)
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Rating:42Neutral
Price Target:
$1.50
▼(-19.79% Downside)
Action:Reiterated
Date:06/18/26
Score is held down primarily by weak financial performance (no revenue, large losses, and ongoing cash burn) and a bearish technical setup (below key moving averages with negative MACD). Corporate events add dilution risk via recent equity offerings, while valuation support is limited due to negative earnings and no dividend.
Positive Factors
Zero reported debt
A zero-debt balance sheet materially reduces default and interest-rate risk and gives management flexibility to prioritize R&D spending. For a clinical-stage biotech, no scheduled interest burdens extends runway capacity and lowers fixed-cost pressure while pursuing lengthy Phase 3 programs.
Negative Factors
No product revenue
Zero revenue is a durable structural constraint: the firm must rely entirely on external funding until a product is commercialized or licensed. This absence of operating income amplifies execution risk and places long-term sustainability on successful trial outcomes or continued capital raises.
Read all positive and negative factors
Positive Factors
Negative Factors
Zero reported debt
A zero-debt balance sheet materially reduces default and interest-rate risk and gives management flexibility to prioritize R&D spending. For a clinical-stage biotech, no scheduled interest burdens extends runway capacity and lowers fixed-cost pressure while pursuing lengthy Phase 3 programs.
Read all positive factors
Annovis Bio (ANVS) vs. SPDR S&P 500 ETF (SPY)
Market Cap
$74.45M
Dividend YieldN/A
Average Volume (3M)1.18M
Price to Earnings (P/E)―
Beta (1Y)2.55
Revenue GrowthN/A
EPS Growth20.55%
CountryUS
Employees8
SectorHealthcare
Sector Strength45
IndustryBiotechnology
Share Statistics
EPS (TTM)-1.72
Shares Outstanding42,541,866
10 Day Avg. Volume1,075,716
30 Day Avg. Volume1,175,497
Financial Highlights & Ratios
PEG Ratio0.02
Price to Book (P/B)4.22
Price to Sales (P/S)0.00
P/FCF Ratio>-0.01
Enterprise Value/Market Cap0.27
Enterprise Value/RevenueN/A
Enterprise Value/Gross ProfitN/A
Enterprise Value/Ebitda-0.49
Forecast
1Y Price Target
$12.50Price Target Upside568.45% Upside
Rating ConsensusModerate Buy
Number of Analyst Covering2
EPS Forecast (FY)-1.6
Revenue Forecast (FY)N/A
Annovis Bio Business Overview & Revenue Model
Company Description
Annovis Bio, Inc. is a clinical-stage biopharmaceutical company focused on pioneering treatments for neurodegenerative disorders. The firm's flagship drug, Buntanetap, an oral medication, has successfully advanced through Phase 2a clinical trials ...
How the Company Makes Money
null...
Annovis Bio Financial Statement Overview
Summary
Income Statement
12
Very Negative
Balance Sheet
46
Neutral
Cash Flow
18
Very Negative
| Breakdown | TTM | Dec 2025 | Mar 2025 | Mar 2024 | Mar 2023 | Dec 2021 |
|---|---|---|---|---|---|---|
Income Statement | ||||||
| Total Revenue | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 |
| Gross Profit | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 |
| EBITDA | -40.92M | -28.85M | -22.74M | -56.20M | -25.33M | -14.50M |
| Net Income | -40.92M | -28.85M | -24.59M | -56.20M | -25.33M | -14.49M |
Balance Sheet | ||||||
| Total Assets | 16.24M | 21.08M | 13.93M | 10.21M | 36.02M | 46.00M |
| Cash, Cash Equivalents and Short-Term Investments | 14.22M | 19.53M | 10.55M | 5.75M | 28.38M | 45.69M |
| Total Debt | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 |
| Total Liabilities | 13.12M | 4.23M | 4.62M | 17.96M | 7.70M | 1.51M |
| Stockholders Equity | 3.13M | 16.85M | 9.31M | -7.75M | 28.32M | 44.49M |
Cash Flow | ||||||
| Free Cash Flow | -26.53M | -25.62B | -21.89B | -39.97M | -17.31M | -9.13M |
| Operating Cash Flow | -26.53M | -25.62B | -21.89B | -39.97M | -17.31M | -9.13M |
| Investing Cash Flow | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 |
| Financing Cash Flow | 18.52M | 34.60B | 26.69B | 17.34M | 4.61K | 46.74M |
Annovis Bio Technical Analysis
Negative
1.87
Price Trends
1.94
Negative
2.22
Negative
2.57
Negative
Market Momentum
-0.08
Positive
41.06
Neutral
20.01
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For ANVS, the sentiment is Negative. The current price of 1.87 is below the 20-day moving average (MA) of 1.88, below the 50-day MA of 1.94, and below the 200-day MA of 2.57, indicating a bearish trend. The MACD of -0.08 indicates Positive momentum. The RSI at 41.06 is Neutral, neither overbought nor oversold. The STOCH value of 20.01 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Negative sentiment for ANVS.
Annovis Bio Risk Analysis
Annovis Bio disclosed 77 risk factors in its most recent earnings report. Annovis Bio reported the most risks in the "Tech & Innovation" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks
Annovis Bio Peers Comparison
UnderperformOutperform
Sector (51)
Name | Overall Rating | Market Cap | P/E Ratio | ROE | Dividend Yield | Revenue Growth | EPS Growth |
|---|---|---|---|---|---|---|---|
52 Neutral | $115.41M | -3.90 | -57.26% | ― | 115.44% | -1.14% | |
51 Neutral | $7.86B | -0.30 | -43.30% | 2.27% | 22.53% | -2.21% | |
50 Neutral | $237.72M | -2.64 | -79.63% | ― | -100.00% | -1124.16% | |
46 Neutral | $163.23M | -1.26 | -123.07% | ― | ― | 3.91% | |
43 Neutral | $175.71M | -1.96 | -81.24% | ― | -11.87% | -86.91% | |
42 Neutral | $74.45M | -1.19 | -318.08% | ― | ― | 20.55% |
* Healthcare Sector Average
ANVS
Annovis Bio
1.75
-0.85
-32.69%
WHWK
Whitehawk Therapeutics
4.42
2.33
111.48%
DTIL
Precision BioSciences
6.81
2.02
42.17%
GLSI
Greenwich LifeSciences
23.38
14.48
162.70%
ABOS
Acumen Pharmaceuticals
2.26
1.06
88.33%
COYA
Coya Therapeutics, Inc.
4.92
-0.58
-10.55%
Annovis Bio Corporate Events
Business Operations and StrategyShareholder Meetings
Annovis Bio Shareholders Approve Governance and Compensation Changes
Positive
Jun 17, 2026
On June 17, 2026, Annovis Bio, Inc. held its 2026 Annual Meeting of Stockholders virtually, with 62.65% of outstanding common shares represented, and shareholders elected all five director nominees and ratified Ernst Young LLP as the company̵...
Business Operations and StrategyPrivate Placements and Financing
Annovis Bio Announces Dilutive Equity Offering for Trials
Negative
May 20, 2026
On May 20, 2026, Annovis Bio entered an underwriting agreement with Canaccord Genuity for a public offering of 7,895,000 common shares and accompanying warrants to purchase up to 7,105,500 shares, priced at a combined $1.90 per share and nine-tent...
Business Operations and StrategyPrivate Placements and Financing
Annovis Bio Prices Registered Direct Offering to Fund Trials
Positive
Apr 10, 2026
On April 9, 2026, Annovis Bio priced an underwritten registered direct offering of 5,263,156 shares of common stock, together with accompanying warrants to purchase an equal number of shares, at a combined price of $1.90 per share and warrant. The...
Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
Disclaimer
This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.