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Cogent Biosciences (COGT)
NASDAQ:COGT
US Market
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Cogent Biosciences (COGT) AI Stock Analysis

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COGT

Cogent Biosciences

(NASDAQ:COGT)

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Neutral 43 (OpenAI - Gpt-5.6Sol)
Rating:43Neutral
Price Target:
$30.00
▼(-18.48% Downside)
Action:Reiterated
Date:09/06/26
The score is held down primarily by weak financial performance (no revenue, expanding losses, and accelerating cash burn alongside higher debt) and bearish technical conditions (below key moving averages with negative MACD and sub-50 RSI). Corporate events provide a modest offset by improving operational preparedness and governance stability, but they are not large enough to outweigh the financial and trend headwinds.
Positive Factors
Manufacturing Readiness
The long-term supply agreement improves manufacturing preparedness for bezuclastinib and supports more reliable operational planning. Secured capacity and rolling forecasts can reduce execution uncertainty as the lead candidate advances, while declining minimum purchase obligations preserve flexibility over its lifecycle.
Negative Factors
Pre-Revenue Loss Profile
The absence of revenue leaves Cogent dependent on financing and future clinical or commercial success to fund operations. Expanding losses and negative gross profit indicate that current activities are not yet generating commercial scale, creating a persistent earnings and execution burden.
Read all positive and negative factors
Positive Factors
Negative Factors
Manufacturing Readiness
The long-term supply agreement improves manufacturing preparedness for bezuclastinib and supports more reliable operational planning. Secured capacity and rolling forecasts can reduce execution uncertainty as the lead candidate advances, while declining minimum purchase obligations preserve flexibility over its lifecycle.
Read all positive factors

Cogent Biosciences (COGT) vs. SPDR S&P 500 ETF (SPY)

Cogent Biosciences Business Overview & Revenue Model

Company Description
Cogent Biosciences, Inc. is a biotechnology firm dedicated to creating targeted treatments for illnesses rooted in specific genetic anomalies. The company's primary therapeutic candidate is CGT9486, a selective tyrosine kinase inhibitor engineered...

Cogent Biosciences Financial Statement Overview

Summary
Financials reflect a pre-revenue biotech with worsening profitability and liquidity pressure: TTM shows no revenue, a large net loss (~$377M) that has expanded versus prior years, and significant cash burn (operating cash flow ~-$308M; free cash flow ~-$309M). While equity remains meaningful (~$532M), it has declined and debt has ramped to ~ $244M, increasing balance-sheet risk if burn persists.
Income Statement
12
Very Negative
Balance Sheet
44
Neutral
Cash Flow
18
Very Negative
BreakdownTTMDec 2025Dec 2024Dec 2023Dec 2022Dec 2021
Income Statement
Total Revenue0.000.000.000.000.000.00
Gross Profit-2.33M-4.62M0.000.000.000.00
EBITDA-372.36M-321.29M-251.51M-188.82M-130.37M-72.13M
Net Income-377.18M-328.94M-255.86M-192.41M-140.24M-72.27M
Balance Sheet
Total Assets834.55M937.61M327.90M313.44M300.81M232.09M
Cash, Cash Equivalents and Short-Term Investments792.30M900.76M287.08M265.71M259.28M219.68M
Total Debt244.26M253.15M17.47M18.85M19.65M3.15M
Total Liabilities302.16M301.24M71.61M55.63M45.08M17.91M
Stockholders Equity532.39M636.37M256.29M257.80M255.74M214.18M
Cash Flow
Free Cash Flow-309.24M-266.00M-208.36M-156.42M-125.50M-60.48M
Operating Cash Flow-307.55M-264.44M-207.79M-153.62M-118.64M-58.76M
Investing Cash Flow-499.99M-399.53M38.28M-97.82M-124.72M-1.72M
Financing Cash Flow861.53M878.23M214.45M163.54M163.56M37.98M

Cogent Biosciences Technical Analysis

Technical Analysis Sentiment
Neutral
Last Price36.80
Price Trends
50DMA
32.97
Negative
100DMA
35.34
Negative
200DMA
35.81
Negative
Market Momentum
MACD
-0.62
Negative
RSI
49.39
Neutral
STOCH
85.18
Negative
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For COGT, the sentiment is Neutral. The current price of 36.8 is above the 20-day moving average (MA) of 30.54, above the 50-day MA of 32.97, and above the 200-day MA of 35.81, indicating a neutral trend. The MACD of -0.62 indicates Negative momentum. The RSI at 49.39 is Neutral, neither overbought nor oversold. The STOCH value of 85.18 is Negative, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Neutral sentiment for COGT.

Cogent Biosciences Risk Analysis

Cogent Biosciences disclosed 61 risk factors in its most recent earnings report. Cogent Biosciences reported the most risks in the "Tech & Innovation" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

Cogent Biosciences Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
70
Outperform
$8.96B113.6412.03%―34.81%44.59%
62
Neutral
$5.93B-53.38-15.65%――-76.46%
56
Neutral
$6.15B-28.70-80.48%―53.51%-3.31%
54
Neutral
$5.06B-123.6521.72%―-42.84%-106.21%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
50
Neutral
$5.22B-5.52-410.20%―44.02%-1101.02%
43
Neutral
$5.42B-13.51-72.57%――4.92%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
COGT
Cogent Biosciences
31.21
15.01
92.65%
PTCT
PTC Therapeutics
60.59
-6.49
-9.68%
PTGX
Protagonist Therapeutics
138.43
63.18
83.96%
RYTM
Rhythm Pharmaceuticals
89.27
-22.28
-19.97%
MIRM
Mirum Pharmaceuticals
80.39
8.81
12.31%
BLTE
Belite Bio, Inc. ADR
147.33
53.51
57.03%

Cogent Biosciences Corporate Events

Business Operations and Strategy
Cogent Biosciences Secures Long-Term Bezuclastinib Supply Deal
Positive
Sep 2, 2026
On September 1, 2026, Cogent Biosciences entered into a Commercial Supply Agreement with Hovione FarmaCiencia to manufacture bezuclastinib spray-dried dispersion and tablets, committing to purchase minimum percentages of its product requirements u...
Private Placements and FinancingRegulatory Filings and Compliance
Cogent Biosciences Announces $400 Million ATM Offering
Neutral
Aug 10, 2026
On August 10, 2026, Cogent Biosciences filed a prospectus supplement with the U.S. Securities and Exchange Commission to enable the sale of up to $400 million in common stock under an existing at-the-market Sales Agreement with Guggenheim Securiti...
Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Sep 06, 2026