BridgeBio Pharma AI Stock Analysis
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BridgeBio Pharma (BBIO) AI Stock Analysis
BridgeBio Pharma
(NASDAQ:BBIO)
BBIO’s score is primarily held back by weak financial performance driven by heavy ongoing losses and significant free-cash-flow burn, despite strong revenue growth and high gross margins. The earnings call meaningfully lifts the outlook due to strong commercial momentum for Attruby and multiple near-term launch catalysts with specific regulatory timelines, while technicals are moderately supportive but not yet a long-term uptrend. Valuation remains constrained by the negative P/E and lack of dividend yield in the provided data.
BridgeBio Pharma Key Performance Indicators (KPIs)
Revenue by SegmentHighlights how much revenue each business segment generates, providing insight into which areas are driving growth and which may need strategic adjustments.
BridgeBio’s revenue mix is shifting decisively from volatile licensing milestones toward recurring commercial economics: Attruby has become the growth engine, while BEYONTTRA royalties are beginning to add a durable second stream. The sharp pullback in license and services revenue is largely a normalization after a prior one-time milestone, not a deterioration in the underlying business. This mix change strengthens the path toward 2027 profitability, though elevated launch spending, payer pressure, and execution across three upcoming launches could keep cash burn high before the portfolio fully scales.
BridgeBio Pharma (BBIO) vs. SPDR S&P 500 ETF (SPY)
- Market Cap
- $15.25B
- Dividend Yield
- ―
- Average Volume (3M)
- 2.69M
- Price to Earnings (P/E)
- -25.8
- Beta (1Y)
- 0.92
- Revenue Growth
- 167.27%
- EPS Growth
- 27.40%
- Country
- US
- Employees
- 1,001
- Sector
- Healthcare
- Sector Strength
- 51
- Industry
- Biotechnology
BridgeBio Pharma Business Overview & Revenue Model
Company Description
BridgeBio Pharma, Inc. is a pharmaceutical company dedicated to identifying, advancing, and providing medical solutions for various genetic conditions. The firm boasts an extensive portfolio comprising 30 distinct development initiatives, spanning th...
How the Company Makes Money
BridgeBio primarily makes money through (1) product revenue from commercialized therapies, where applicable, generated via sales to wholesalers/distributors, specialty pharmacies, hospitals, and other healthcare providers (net of rebates, discounts,...
BridgeBio Pharma Earnings Call Summary
The call was strongly positive, with substantial Attruby revenue growth, favorable real-world and clinical evidence, a $1.5 billion cash position, improved operating results and three potential product launches within seven months. The company also advanced encaleret into a Phase III chronic hypoparathyroidism study and expanded its pipeline. The main negatives were higher operating expenses, continued operating losses, a large portion of prescribers not yet using Attruby, limited visibility into market share pending Pfizer's results, and the later European filing timeline for BBP-418.
Q3-2026 Updates
Positive Updates
Negative Updates
Company Guidance
Management said Attruby is tracking to meet or beat its $4 billion peak year sales assumption, with $4 billion in peak year sales across the other 3 brands, and that $25 million to $30 million is the right number near term for sequential revenue growth, with the number eventually going up more from there. The company expects 3 launches in the next 7 months: BBP-418 on November 27, infigratinib on February 4, 2027, and encaleret on May 8, 2027; it expects to reach at least 90% of MDA centers by PDUFA for BBP-418, fully penetrate the 500 identified patient pool by year 3, submit an MAA for BBP-418 in the first half of 2028, and submit top-line FORTIFY month 36 results in late '27 or early '28. Management anticipates OpEx will catch up in the fourth quarter of this year, followed by a more modest steady growth paired with improvement of the operating line throughout 2027 and beyond; it expects to average an operating loss of around $90 million to $100 million a quarter this year versus about $130 million loss a quarter last year, move towards a breakeven point throughout 2027, and reach 2028 where all 4 of the brands have a chance to be profitable on a stand-alone basis. RECLAIM-HP will enroll approximately 160 individuals, with top line results anticipated in the next 15 months.
BridgeBio Pharma Financial Statement Overview
Summary
Strong TTM revenue base ($845.7M, +18.6%) and very high gross margins (~94%) are positives, and losses have improved versus prior years. However, profitability remains deeply negative (TTM net margin -70.5%, EBIT margin -52.2%) and cash burn is substantial (TTM operating cash flow -$369.0M; free cash flow -$374.3M), which is the main financial constraint despite improved leverage in TTM.
Income Statement
38NegativeBalance Sheet
62PositiveCash Flow
34Negative| Breakdown | TTM | Dec 2025 | Dec 2024 | Dec 2023 | Dec 2022 | Dec 2021 |
|---|---|---|---|---|---|---|
Income Statement | ||||||
| Total Revenue | 945.54M | 502.08M | 221.90M | 9.30M | 77.65M | 69.72M |
| Gross Profit | 884.20M | 473.81M | 218.02M | 6.86M | 74.21M | 66.60M |
| EBITDA | -440.58M | -676.45M | -436.83M | -565.47M | -397.44M | -533.83M |
| Net Income | -570.21M | -729.31M | -535.76M | -643.20M | -481.18M | -562.54M |
Balance Sheet | ||||||
| Total Assets | 2.16B | 936.02M | 919.34M | 546.38M | 623.04M | 1.01B |
| Cash, Cash Equivalents and Short-Term Investments | 1.54B | 587.48M | 681.10M | 434.88M | 471.92M | 836.66M |
| Total Debt | 2.49B | 2.73B | 1.73B | 1.74B | 1.72B | 1.73B |
| Total Liabilities | 3.82B | 3.01B | 2.38B | 1.89B | 1.87B | 1.88B |
| Stockholders Equity | -1.66B | -2.08B | -1.47B | -1.35B | -1.25B | -870.41M |
Cash Flow | ||||||
| Free Cash Flow | -374.31M | -447.01M | -521.66M | -529.03M | -425.81M | -546.18M |
| Operating Cash Flow | -368.97M | -445.91M | -520.73M | -527.72M | -419.49M | -497.93M |
| Investing Cash Flow | -1.99M | -24.49M | 60.78M | 54.03M | 453.15M | -200.83M |
| Financing Cash Flow | 1.26B | 359.29M | 748.46M | 451.54M | -13.13M | 736.45M |
BridgeBio Pharma Technical Analysis
Price Trends
Market Momentum
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For BBIO, the sentiment is Positive. The current price of 78.30 is above the 20-day moving average (MA) of 73.10, above the 50-day MA of 69.98, and above the 200-day MA of 72.69, indicating a bullish trend. The MACD of 2.65 indicates Negative momentum. The RSI at 64.95 is Neutral, neither overbought nor oversold. The STOCH value of 76.19 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Positive sentiment for BBIO.
BridgeBio Pharma Risk Analysis
BridgeBio Pharma disclosed 102 risk factors in its most recent earnings report. BridgeBio Pharma reported the most risks in the "Tech & Innovation" category.
Latest Risks Added
3 New RisksBridgeBio Pharma Peers Comparison
Overall Rating
SRPT60Neutral
BMRN56Neutral
PTCT56Neutral
BBIO53Neutral
RARE48Neutral
IONS42Neutral
Financial Indicators
| Name | Overall Rating | Market Cap | P/E Ratio | ROE | Dividend Yield | Revenue Growth | EPS Growth |
|---|---|---|---|---|---|---|---|
| 60Neutral | $1.72B | 178.56 | 1.04% | ― | -18.95% | 59.85% | |
| 56Neutral | $10.98B | -635.89 | -0.31% | ― | 19.76% | -103.57% | |
| 56Neutral | $5.29B | -48.47 | 57.10% | ― | -35.05% | -113.73% | |
| 53Neutral | $15.23B | -25.76 | 26.76% | ― | 167.27% | 27.40% | |
| Sector * | 51Neutral | $7.86B | -0.30 | -43.30% | 2.27% | 22.53% | -2.21% |
| 48Neutral | $1.66B | -3.10 | 213.22% | ― | 15.76% | 12.63% | |
| 42Neutral | $4.55B | -8.75 | -120.44% | ― | -0.79% | -106.48% |
* Healthcare Sector Average
Performance Comparison
| Show on chart | Ticker | Company Name | Price | Change | % Change |
|---|---|---|---|---|---|
| BBIO | Bridgebio Pharma | 78.30 | 11.40 | 17.04% | |
| BMRN | Biomarin Pharmaceutical Inc. | 57.23 | 2.77 | 5.09% | |
| IONS | Ionis Pharmaceuticals Inc. | 29.06 | -44.20 | -60.33% | |
| SRPT | Sarepta Therapeutics Inc. | 16.07 | -1.47 | -8.38% | |
| PTCT | PTC Therapeutics | 63.49 | -12.11 | -16.02% | |
| RARE | Ultragenyx Pharmaceutical, Inc. | 16.08 | -16.46 | -50.58% |
BridgeBio Pharma Corporate Events
BridgeBio Wins FDA Priority Review for Infigratinib
PositiveOn October 6, 2026, BridgeBio Pharma reported that the U.S. Food and Drug Administration accepted and granted Priority Review to its New Drug Application for oral infigratinib in children with achondroplasia, setting a Prescription Drug User Fee Act...
BridgeBio Pharma Expands Access to Rare Disease Therapies
PositiveOn August 31, 2026, BridgeBio Pharma announced a voluntary agreement with the U.S. government aimed at expanding access to its medicines and lowering costs for American patients, particularly those with rare genetic diseases. The deal is structured t...
BridgeBio Pharma announces major secondary share offering
NeutralOn August 13, 2026, BridgeBio Pharma, Inc. and selling stockholder KKR Genetic Disorder L.P. agreed with underwriters led by William Blair, Goldman Sachs and KKR Capital Markets to conduct a secondary offering of 5,000,000 shares of BridgeBio common...
Disclaimer
This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.
Date of analysis: Oct 30, 2026
