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Aurinia Pharmaceuticals (AUPH)
NASDAQ:AUPH
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Aurinia Pharmaceuticals (AUPH) AI Stock Analysis

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AUPH

Aurinia Pharmaceuticals

(NASDAQ:AUPH)

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Outperform 79 (OpenAI - 4o)
Rating:79Outperform
Price Target:
$15.00
▲(13.90% Upside)
Aurinia Pharmaceuticals demonstrates strong financial performance and positive earnings call highlights, contributing to a favorable outlook. However, the stock's high valuation and technical indicators suggest caution. The absence of corporate events further consolidates the focus on financial and earnings performance.
Positive Factors
Revenue Growth
Aurinia's consistent revenue growth indicates strong market demand for LUPKYNIS, enhancing its competitive position in the kidney disease treatment market.
Cash Flow Management
Positive cash flow from operations reflects effective cash management and operational efficiency, supporting long-term financial stability.
Clinical Development
Successful clinical trials for new compounds like aritinercept can expand Aurinia's product pipeline, driving future growth and innovation.
Negative Factors
Cash and Investments Decrease
A decrease in cash and investments could limit Aurinia's ability to fund future growth initiatives or respond to unexpected financial challenges.
Share Repurchase Impact
Significant share repurchases may strain cash reserves, potentially impacting liquidity and limiting investment in growth opportunities.
Profitability Challenges
Historical profitability challenges suggest potential risks in maintaining current margins, which could affect long-term financial performance.

Aurinia Pharmaceuticals (AUPH) vs. SPDR S&P 500 ETF (SPY)

Aurinia Pharmaceuticals Business Overview & Revenue Model

Company DescriptionAurinia Pharmaceuticals Inc. is a biotechnology company focused on developing and commercializing innovative therapies for kidney diseases, particularly lupus nephritis. The company is primarily engaged in the research and development of its lead product, LUPKYNIS (voclosporin), which is designed to improve renal response in patients with this autoimmune condition. Based in Victoria, British Columbia, Aurinia operates in the biopharmaceutical sector, leveraging its expertise in immunology and nephrology to address significant unmet medical needs.
How the Company Makes MoneyAurinia Pharmaceuticals generates revenue primarily through the sale of its commercialized product, LUPKYNIS, which was approved by the FDA for the treatment of lupus nephritis. The company earns income from product sales to healthcare providers and patients, and it may also benefit from potential royalties and milestone payments if it enters into partnerships or collaborations with larger pharmaceutical companies for further development and commercialization of its pipeline products. Additionally, Aurinia may receive funding through research grants or government programs aimed at supporting innovative drug development in the healthcare sector.

Aurinia Pharmaceuticals Earnings Call Summary

Earnings Call Date:Oct 30, 2025
(Q2-2025)
|
% Change Since: |
Next Earnings Date:Mar 04, 2026
Earnings Call Sentiment Positive
Aurinia Pharmaceuticals reported strong financial performance with significant revenue and net product sales growth, improved cash flow, increased guidance, and successful clinical trial results. However, there were decreases in cash, cash equivalents, and investments due to share repurchases.
Q2-2025 Updates
Positive Updates
Strong Revenue Growth
Total revenue for the 3 and 6 months ended June 30, 2025, was $70 million and $132.5 million, up 22% and 23%, respectively, from the same periods in 2024.
Increased Net Product Sales of LUPKYNIS
Net product sales for LUPKYNIS were $66.6 million and $126.5 million for the 3 and 6 months ended June 30, 2025, representing increases of 21% and 23%, respectively, from the same periods in 2024.
Positive Cash Flow from Operations
Cash flow generated from operations was $45.5 million for the 6 months ended June 30, 2025, compared to a negative $2.8 million in the same period of 2024.
Raised Full Year 2025 Revenue Guidance
Full year 2025 total revenue guidance was increased from $250-260 million to $260-270 million, and net product sales guidance was raised from $240-250 million to $250-260 million.
Successful Aritinercept Phase I Study
Reported positive results from the aritinercept Phase I single ascending dose study, with plans to initiate further clinical studies in the second half of the year.
Improved Gross Margin
Gross margin for the 3 and 6 months ended June 30, 2025, was 90% and 88%, respectively, compared to 84% and 85% in the same periods in 2024.
Reduced Operating Expenses
Total operating expenses decreased to $49.9 million and $90.5 million for the 3 and 6 months ended June 30, 2025, from $58.7 million and $122.3 million in the comparable periods of 2024.
Net Income Increase
Net income for the 3 and 6 months ended June 30, 2025, was $21.5 million and $44.9 million, respectively, compared to $722,000 and a net loss of $10 million in the same periods of 2024.
Negative Updates
Decrease in Cash and Investments
Cash, cash equivalents, restricted cash, and investments decreased from $358.5 million at the end of 2024 to $315.1 million as of June 30, 2025.
Share Repurchase Impact
The company repurchased $11.2 million of its common shares for $90.8 million, impacting available cash resources.
Company Guidance
During the Aurinia Pharmaceuticals second-quarter 2025 earnings call, the company increased its full-year 2025 total revenue guidance from a range of $250 million to $260 million to a range of $260 million to $270 million, and its net product sales guidance from $240 million to $250 million to a range of $250 million to $260 million, citing sustained growth. Total revenue for the three and six months ended June 30, 2025, was $70 million and $132.5 million, reflecting a 22% and 23% increase from the same periods in 2024, primarily driven by increased sales of LUPKYNIS. Additionally, the company generated $45.5 million in cash flow from operations in the first half of 2025, a significant turnaround from a negative $2.8 million in the same period of 2024, and held $315.1 million in cash and investments as of June 30, 2025. The company's strategic restructuring in 2024 contributed to lower operating expenses, which were $49.9 million for the second quarter, down from $58.7 million in the same period of 2024. Aurinia also announced positive results from its aritinercept Phase I study and intends to initiate further clinical studies for this compound in at least two autoimmune diseases in the second half of 2025.

Aurinia Pharmaceuticals Financial Statement Overview

Summary
Aurinia Pharmaceuticals is on a positive financial trajectory, marked by strong revenue growth, improved profitability, and effective cash flow management. The solid equity position and conservative leverage enhance financial stability. While past challenges in profitability and cash flow variability are noted, the recent financial performance suggests the company is well-positioned for future growth. Continued attention to capital management and operational efficiency will be key to sustaining this momentum.
Income Statement
85
Very Positive
Aurinia Pharmaceuticals has demonstrated impressive revenue growth and profitability improvement. The TTM (Trailing-Twelve-Months) data shows a significant increase in total revenue by 10.63% compared to the previous year. Net profit margin improved substantially from the previous negative figures to a positive 23.31%. Both EBIT and EBITDA margins are strong at 20.00% and 30.15%, respectively, reflecting effective cost management and operational efficiency. However, the company previously faced some profitability challenges which are important to monitor.
Balance Sheet
78
Positive
The balance sheet reflects a solid equity position with an equity ratio of 66.70%, indicating financial stability. The debt-to-equity ratio stands at 0.24, suggesting conservative leverage and a manageable debt load. Return on equity has improved to 18.08%, showing enhanced shareholder value creation. However, a reduction in stockholders' equity suggests a need for careful capital management moving forward.
Cash Flow
82
Very Positive
Aurinia Pharmaceuticals shows strong cash flow management with a notable increase in free cash flow, growing by 109.41% year-over-year. The operating cash flow to net income ratio is 1.53, indicating efficient conversion of earnings into cash. Free cash flow to net income ratio is also robust at 1.52, reflecting the company’s strong cash-generating ability. Nevertheless, past periods show some variability in cash flow performance.
BreakdownTTMDec 2024Dec 2023Dec 2022Dec 2021Dec 2020
Income Statement
Total Revenue260.11M235.13M175.51M134.03M45.60M50.12M
Gross Profit232.84M206.88M161.37M128.37M44.51M-209.00K
EBITDA86.50M31.73M-63.05M-103.65M-177.44M-102.92M
Net Income60.64M5.75M-78.02M-108.18M-180.97M-102.68M
Balance Sheet
Total Assets502.56M550.64M548.06M470.86M543.37M463.66M
Cash, Cash Equivalents and Short-Term Investments315.13M358.48M350.49M389.39M466.08M398.33M
Total Debt81.83M79.37M97.61M8.09M8.74M8.41M
Total Liabilities167.26M173.17M170.11M65.42M64.28M55.91M
Stockholders Equity335.30M377.48M377.95M405.44M479.09M407.75M
Cash Flow
Free Cash Flow92.38M44.11M-34.18M-79.82M-159.19M-77.20M
Operating Cash Flow92.66M44.39M-33.46M-79.53M-157.69M-69.86M
Investing Cash Flow46.41M39.26M-6.71M-60.63M-103.87M-158.19M
Financing Cash Flow-119.50M-49.09M-5.13M2.43M221.11M194.38M

Aurinia Pharmaceuticals Technical Analysis

Technical Analysis Sentiment
Positive
Last Price13.17
Price Trends
50DMA
12.08
Positive
100DMA
10.75
Positive
200DMA
9.39
Positive
Market Momentum
MACD
0.18
Negative
RSI
65.98
Neutral
STOCH
71.33
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For AUPH, the sentiment is Positive. The current price of 13.17 is above the 20-day moving average (MA) of 11.79, above the 50-day MA of 12.08, and above the 200-day MA of 9.39, indicating a bullish trend. The MACD of 0.18 indicates Negative momentum. The RSI at 65.98 is Neutral, neither overbought nor oversold. The STOCH value of 71.33 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Positive sentiment for AUPH.

Aurinia Pharmaceuticals Risk Analysis

Aurinia Pharmaceuticals disclosed 36 risk factors in its most recent earnings report. Aurinia Pharmaceuticals reported the most risks in the "Legal & Regulatory" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

Aurinia Pharmaceuticals Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
$1.60B28.3417.33%25.59%
$1.72B51.1421.48%162.30%
$1.67B-5.38%26.90%62.72%
$2.27B-4.76%64.89%-221.56%
$7.86B-0.30-43.30%2.27%22.53%-2.21%
$1.78B-8.89-27.17%-30.25%-9.70%
$1.54B45.85%76.36%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
AUPH
Aurinia Pharmaceuticals
13.17
5.85
79.92%
BCRX
BioCryst
7.32
-1.11
-13.17%
CLDX
Celldex
26.73
1.05
4.09%
MNKD
MannKind
5.59
-1.58
-22.04%
SRPT
Sarepta Therapeutics
24.01
-99.28
-80.53%
IMCR
Immunocore Holdings
33.09
1.39
4.38%

Aurinia Pharmaceuticals Corporate Events

Aurinia Pharmaceuticals Advances Voclosporin Study in Young Lupus Nephritis Patients
Oct 27, 2025

Study Overview: Aurinia Pharmaceuticals is conducting a study titled An Open-Label Extension Study to Assess the Long-Term Safety and Efficacy of Voclosporin in Adolescent and Pediatric Subjects With Lupus Nephritis. The study aims to evaluate the long-term safety and tolerability of voclosporin over an additional 12 months in young patients who have completed previous treatment for lupus nephritis. This research is significant as it addresses the need for effective long-term treatment options for this condition in younger populations.

Aurinia Pharmaceuticals Advances Lupus Nephritis Study in Young Patients
Oct 27, 2025

Study Overview: Aurinia Pharmaceuticals is conducting a study titled A Double-Blind, Placebo-Controlled, Dose Escalation Study to Assess the Efficacy, Safety and Pharmacokinetics of Voclosporin in Adolescent and Pediatric Subjects With Lupus Nephritis. The study aims to evaluate the efficacy and safety of voclosporin in achieving renal response in young patients with active lupus nephritis over 24 weeks, highlighting its potential significance in treating this condition.

Business Operations and StrategyProduct-Related Announcements
Aurinia Pharmaceuticals to Present New LUPKYNIS Data at Key Conferences
Positive
Oct 15, 2025

Aurinia Pharmaceuticals announced that new data on LUPKYNIS (voclosporin) will be presented at the American College of Rheumatology Convergence and the American Society of Nephrology Kidney Week 2025. These presentations, in collaboration with independent investigators, will highlight real-world effectiveness, usage in pediatric patients, and the drug’s distribution and clearance. The findings aim to enhance the medical community’s understanding of voclosporin’s role in treating lupus nephritis, reinforcing Aurinia’s commitment to advancing patient care.

The most recent analyst rating on (AUPH) stock is a Buy with a $13.00 price target. To see the full list of analyst forecasts on Aurinia Pharmaceuticals stock, see the AUPH Stock Forecast page.

Business Operations and StrategyProduct-Related Announcements
Aurinia Pharmaceuticals Reaffirms Confidence in LUPKYNIS After Retraction
Positive
Sep 30, 2025

Aurinia Pharmaceuticals responded to a retracted LinkedIn post by an FDA official regarding voclosporin, affirming the positive benefit/risk profile of its product LUPKYNIS. The drug, approved by the FDA in January 2021 and for long-term use in April 2024, has shown sustained efficacy and safety in clinical studies, reinforcing Aurinia’s position in the autoimmune treatment market.

The most recent analyst rating on (AUPH) stock is a Buy with a $11.00 price target. To see the full list of analyst forecasts on Aurinia Pharmaceuticals stock, see the AUPH Stock Forecast page.

Aurinia Pharmaceuticals’ Earnings Call: Strong Growth and Optimism
Aug 2, 2025

Aurinia Pharmaceuticals’ recent earnings call paints a picture of robust financial health, marked by significant revenue growth, improved cash flow, and encouraging clinical trial outcomes. While concerns about decreased cash reserves and restructuring costs were noted, the overall sentiment leans towards optimism, driven by the company’s strong performance and increased guidance.

Aurinia Pharmaceuticals Reports Strong Revenue Growth
Aug 1, 2025

Aurinia Pharmaceuticals is a biopharmaceutical company dedicated to developing treatments for autoimmune diseases, with a notable product, LUPKYNIS, the first FDA-approved oral therapy for lupus nephritis.

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Nov 01, 2025