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Immunocore Holdings (IMCR)
NASDAQ:IMCR
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Immunocore Holdings (IMCR) AI Stock Analysis

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IMCR

Immunocore Holdings

(NASDAQ:IMCR)

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Neutral 54 (OpenAI - Gpt-5.6Sol)
Rating:54Neutral
Price Target:
$33.00
▼(-10.20% Downside)
Action:Reiterated
Date:10/21/26
The score is held back primarily by weak financial quality (ongoing losses, elevated leverage, and renewed TTM cash burn). Offsetting this, the latest earnings call was notably positive on commercial growth, survival data, and pipeline execution progress, while technicals are mixed and valuation remains challenging due to negative earnings and no indicated dividend support.
Positive Factors
Revenue growth and gross margins
Rapid revenue scaling combined with exceptionally high and stable gross margins indicates strong product-level economics as KIMMTRAK adoption expands. This creates operating leverage potential, supports continued commercial investment, and provides a durable foundation for improving profitability as the business matures.
Negative Factors
Persistent losses and cash burn
Despite improving losses, the company has not yet reached consistent profitability or self-funding cash generation. Continued operating and free-cash-flow deficits can constrain reinvestment flexibility and may require financing or balance-sheet resources while commercial and pipeline programs scale.
Read all positive and negative factors
Positive Factors
Negative Factors
Revenue growth and gross margins
Rapid revenue scaling combined with exceptionally high and stable gross margins indicates strong product-level economics as KIMMTRAK adoption expands. This creates operating leverage potential, supports continued commercial investment, and provides a durable foundation for improving profitability as the business matures.
Read all positive factors

Immunocore Holdings Key Performance Indicators (KPIs)

Any
Any
Revenue by Geography
Revenue by Geography
Breaks down Immunocore’s revenue by country or region to show which markets are driving income from product sales and partnership deals. Helps investors assess commercial traction, market diversification, and where regulatory or competitive hurdles could slow expansion.
Chart InsightsImmunocore's revenue from the United States and Europe shows strong recovery, with the U.S. seeing a 15% increase and Europe experiencing a remarkable 115% growth year-on-year, driven by successful launches in key markets. However, international revenue outside these regions remains inconsistent, reflecting variability in buying patterns. The company's robust financial health and strategic global expansion, particularly with KIMMTRAK, underpin its growth trajectory, despite increased operating expenses and moderated future growth expectations.
Data provided by:The Fly

Immunocore Holdings (IMCR) vs. SPDR S&P 500 ETF (SPY)

Immunocore Holdings Business Overview & Revenue Model

Company Description
Immunocore Holdings plc, a biotechnology firm established in 1999 and based in Abingdon, United Kingdom, has reached the commercial stage in its mission to create pioneering immunotherapies. The company's development pipeline addresses a range of ...
How the Company Makes Money
Immunocore makes money primarily through (1) product revenue from the sale of its commercial therapy KIMMTRAK (tebentafusp) in approved markets, and (2) collaboration and licensing-related revenue generated from strategic partnerships that use or ...

Immunocore Holdings Earnings Call Summary

Earnings Call Date:Aug 06, 2026
(Q2-2026)
|
% Change Since: |
Next Earnings Date:Nov 11, 2026
Earnings Call Sentiment Positive
The call was strongly positive, supported by 16% first-half KIMMTRAK revenue growth, 18% second-quarter growth, landmark five-year survival data, improving net losses, a strong cash position, and progress across three phase III melanoma trials and multiple early-stage programs. The main challenges were moderating underlying sequential growth, a Q3 inventory-related headwind, higher second-half rebate payments, and continued unmet need and exploratory-stage development in certain indications.
Positive Updates
KIMMTRAK First-Half Revenue Growth
KIMMTRAK generated $223 million in net revenue during the first half of 2026, representing 16% growth compared with the first half of 2025.
Negative Updates
Distributor Inventory Stocking Creates a Q3 Headwind
Approximately $6 million of U.S. distributor inventory stocking contributed to Q2 sales, and management said the inventory increase will create a headwind in Q3.
Read all updates
Q2-2026 Updates
Negative
KIMMTRAK First-Half Revenue Growth
KIMMTRAK generated $223 million in net revenue during the first half of 2026, representing 16% growth compared with the first half of 2025.
Read all positive updates
Company Guidance
Immunocore expects moderating growth for KIMMTRAK, with underlying quarterly sequential growth of 3%; R&D expenses are expected to modestly increase year-over-year, although at a slower rate than in 2025; sales-related rebates are expected to be approximately $120 million during the second half of this year and return in 2027 to similar amounts as paid in 2025, which was in the $65 million-$70 million range; TEBE-AM enrollment is nearing the target of 540 patients, with top-line data still expected as early as the end of this year, while TEBE-AM headline data could be as early as the end of 2026; PRISM-MEL-301 enrollment completion is targeted by late 2027; updated PRAME data are expected by the end of the year, initial preproinsulin data in 2027, the first Type 1 diabetes patient is expected to be dosed in the coming weeks, the CTA for the second autoimmune candidate is expected by the end of 2026, and HIV data are planned for the first half of 2027.

Immunocore Holdings Financial Statement Overview

Summary
Strong revenue scaling and exceptionally high gross margins are positives, but the company is still loss-making, leverage is elevated (debt-to-equity above 1.0 in 2024–2025 and still high in TTM), and the latest TTM returned to larger operating and free-cash-flow burn.
Income Statement
62
Positive
Balance Sheet
45
Neutral
Cash Flow
38
Negative
BreakdownTTMDec 2025Dec 2024Dec 2023Dec 2022Dec 2021
Income Statement
Total Revenue403.72M297.57M247.98M197.39M144.23M27.04M
Gross Profit399.07M291.36M242.44M196.57M138.94M27.04M
EBITDA16.43M387.18K-37.66M-40.87M――
Net Income-9.33M-26.42M-40.81M-43.75M-43.46M-133.45M
Balance Sheet
Total Assets1.12B1.07B1.01B472.44M526.76M407.28M
Cash, Cash Equivalents and Short-Term Investments880.21M864.15M820.38M350.27M402.47M321.06M
Total Debt434.96M436.69M432.72M66.50M81.45M86.16M
Total Liabilities699.62M686.24M648.79M180.55M187.86M175.76M
Stockholders Equity419.80M381.03M360.72M291.89M338.90M231.53M
Cash Flow
Free Cash Flow-62.53M-11.20M20.89M-1.97M-51.41M-144.49M
Operating Cash Flow-56.34M-7.97M26.06M2.33M-49.21M-143.11M
Investing Cash Flow7.80M-12.16M-355.13M-4.29M-2.20M-1.28M
Financing Cash Flow22.64M9.20M343.88M27.18M145.44M288.19M

Immunocore Holdings Technical Analysis

Technical Analysis Sentiment
Positive
Last Price36.75
Price Trends
50DMA
32.85
Negative
100DMA
32.37
Negative
200DMA
31.81
Positive
Market Momentum
MACD
-0.32
Negative
RSI
57.65
Neutral
STOCH
83.00
Negative
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For IMCR, the sentiment is Positive. The current price of 36.75 is above the 20-day moving average (MA) of 30.03, above the 50-day MA of 32.85, and above the 200-day MA of 31.81, indicating a neutral trend. The MACD of -0.32 indicates Negative momentum. The RSI at 57.65 is Neutral, neither overbought nor oversold. The STOCH value of 83.00 is Negative, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Positive sentiment for IMCR.

Immunocore Holdings Risk Analysis

Immunocore Holdings disclosed 103 risk factors in its most recent earnings report. Immunocore Holdings reported the most risks in the "Tech & Innovation" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

Immunocore Holdings Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
57
Neutral
$1.85B-11.59-28.66%―-28.56%10.25%
56
Neutral
$1.05B-10.26-10.79%―5366.97%8.50%
54
Neutral
$1.65B-177.98-2.35%―20.19%―
54
Neutral
$2.01B-13.92-72.07%―-69.78%-106.07%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
48
Neutral
$1.12B-4.30-47.04%―-65.40%-164.71%
44
Neutral
$546.93M-5.33-38.46%―-87.03%-179.91%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
IMCR
Immunocore Holdings
32.12
0.52
1.65%
XNCR
Xencor
25.84
13.50
109.40%
CTMX
CytomX Therapeutics
2.44
-0.86
-26.06%
ZYME
Zymeworks
28.44
11.03
63.35%
IMTX
Immatics
7.54
-2.64
-25.93%
JANX
Janux Therapeutics Inc
17.06
-7.40
-30.25%

Immunocore Holdings Corporate Events

Business Operations and StrategyProduct-Related Announcements
Immunocore Completes Enrollment in Phase 3 Melanoma Trial
Positive
Sep 14, 2026
On September 14, 2026, Immunocore announced it had reached target enrollment of 540 patients in its global, randomized Phase 3 TEBE-AM trial of KIMMTRAK (tebentafusp) as monotherapy and in combination with pembrolizumab in previously treated, HLA-...
Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Oct 21, 2026