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Celldex Therapeutics (CLDX)
NASDAQ:CLDX
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Celldex (CLDX) AI Stock Analysis

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CLDX

Celldex

(NASDAQ:CLDX)

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Neutral 57 (OpenAI - 5.2)
Rating:57Neutral
Price Target:
$43.00
▲(21.88% Upside)
Action:Reiterated
Date:08/07/26
The score is primarily held back by weak financial performance (persistent and widening losses, near-zero TTM revenue, and accelerating cash burn) despite a strong, low-leverage balance sheet. Technicals are supportive with a strong uptrend, but overbought indicators add near-term risk. Valuation provides limited support due to negative earnings and no dividend, while the recent corporate event is modestly positive but includes a potential dilution consideration.
Positive Factors
Low leverage / strong balance sheet
Celldex’s balance sheet shows very low debt and sizable equity, materially reducing solvency and refinancing risk for a capital-intensive biotech. This durable financial flexibility supports multi-year clinical programs and provides runway to fund R&D without immediate operating revenue.
Negative Factors
Accelerating cash burn
Operating and free cash flows are persistently negative and have accelerated in the trailing twelve months, increasing funding pressure. This structural cash burn raises the probability of near-term financing needs and constrains the firm’s ability to self-fund pivotal trials without external capital.
Read all positive and negative factors
Positive Factors
Negative Factors
Low leverage / strong balance sheet
Celldex’s balance sheet shows very low debt and sizable equity, materially reducing solvency and refinancing risk for a capital-intensive biotech. This durable financial flexibility supports multi-year clinical programs and provides runway to fund R&D without immediate operating revenue.
Read all positive factors

Celldex (CLDX) vs. SPDR S&P 500 ETF (SPY)

Celldex Business Overview & Revenue Model

Company Description
Celldex Therapeutics, Inc. is a biopharmaceutical company dedicated to developing antibody-based treatments, specifically monoclonal and bispecific antibodies, for a range of diseases. Their pipeline features therapeutic candidates aimed at both i...
How the Company Makes Money
Celldex is a clinical-stage biotechnology company and, as such, it typically does not generate recurring revenue from marketed products. Its earnings potential and reported revenue, when present, generally come from (a) collaboration and licensing...

Celldex Financial Statement Overview

Summary
Overall financials are mixed: a very strong, low-debt balance sheet (reducing solvency risk) is offset by structurally negative profitability, near-zero and deteriorating TTM revenue, and accelerating operating/free cash burn in TTM. The company remains dependent on continued funding and pipeline progress rather than operating earnings.
Income Statement
18
Very Negative
Balance Sheet
82
Very Positive
Cash Flow
34
Negative
BreakdownTTMDec 2025Dec 2024Dec 2023Dec 2022Dec 2021
Income Statement
Total Revenue112.00K1.50M7.02M6.88M2.36M4.65M
Gross Profit-63.67M1.50M-156.53M-111.13M-79.90M-48.66M
EBITDA-297.20M-255.42M-154.69M-139.03M-104.20M-66.08M
Net Income-300.59M-258.80M-157.86M-141.43M-112.33M-70.51M
Balance Sheet
Total Assets782.35M582.98M792.34M465.63M352.74M444.65M
Cash, Cash Equivalents and Short-Term Investments717.59M518.57M725.28M421.70M304.95M408.25M
Total Debt4.90M2.34M3.81M2.54M4.03M3.04M
Total Liabilities67.78M55.82M45.34M36.46M26.53M25.18M
Stockholders Equity714.56M527.16M747.00M429.17M326.20M419.48M
Cash Flow
Free Cash Flow-241.82M-213.66M-159.70M-109.11M-105.56M-62.16M
Operating Cash Flow-235.57M-210.94M-157.78M-107.29M-103.73M-60.91M
Investing Cash Flow-67.13M209.07M-290.13M-105.78M89.94M-216.16M
Financing Cash Flow327.11M2.39M441.45M218.46M4.08M272.37M

Celldex Technical Analysis

Technical Analysis Sentiment
Positive
Last Price35.28
Price Trends
50DMA
36.09
Positive
100DMA
34.14
Positive
200DMA
30.32
Positive
Market Momentum
MACD
2.10
Negative
RSI
65.27
Neutral
STOCH
87.29
Negative
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For CLDX, the sentiment is Positive. The current price of 35.28 is below the 20-day moving average (MA) of 38.65, below the 50-day MA of 36.09, and above the 200-day MA of 30.32, indicating a bullish trend. The MACD of 2.10 indicates Negative momentum. The RSI at 65.27 is Neutral, neither overbought nor oversold. The STOCH value of 87.29 is Negative, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Positive sentiment for CLDX.

Celldex Risk Analysis

Celldex disclosed 2 risk factors in its most recent earnings report. Celldex reported the most risks in the "Legal & Regulatory" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

Celldex Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
62
Neutral
$2.26B-14.04-49.73%1083.56%30.89%
60
Neutral
$3.05B-9.63-40.51%34.52%41.20%
59
Neutral
$2.57B-11.49-37.99%-36.24%11.52%
59
Neutral
$2.76B-7.88-76.09%-58.40%-31.99%
57
Neutral
$3.52B-9.77-52.36%-97.27%-44.90%
52
Neutral
$3.18B-10.40-50.56%-100.00%18.12%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
CLDX
Celldex
42.61
17.11
67.10%
NKTR
Nektar Therapeutics
75.92
48.66
178.50%
IOVA
Iovance Biotherapeutics
6.52
3.97
155.69%
NRIX
Nurix Therapeutics
27.19
16.61
156.99%
NUVB
Nuvation Bio
6.10
3.35
121.82%
IMNM
Immunome
26.42
16.14
157.00%

Celldex Corporate Events

Business Operations and StrategyShareholder Meetings
Celldex Shareholders Approve Expanded Equity Incentive Plan
Positive
Jun 26, 2026
At its June 25, 2026 annual meeting, Celldex Therapeutics stockholders approved an amendment to the company’s 2021 Omnibus Equity Incentive Plan, increasing the shares available for issuance by 3,400,000 to a total of 12,900,000 and clarifyi...
Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Aug 07, 2026