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WDNA

WisdomTree BioRevolution Fund (WDNA)

Rating:58Neutral
Price Target:$23.00â–¼(-6.52% Downside)

WDNA, the WisdomTree BioRevolution Fund, appears to be a solid but not top-tier option, with its rating driven by a mix of strong blue-chip and innovative biotech holdings alongside more financially challenged names. High-quality companies like Johnson & Johnson, Eli Lilly, United Therapeutics, and Natera support the fund’s quality through strong financial performance, revenue growth, and generally positive momentum, while weaker holdings such as Twist Bioscience and Iovance Biotherapeutics, which face ongoing losses and bearish or mixed technical trends, weigh on the overall rating. The main risk factor is the fund’s concentration in biotech and life sciences, where many companies have profitability and valuation challenges, making the ETF more sensitive to sector-specific setbacks and volatility.

Positive Factors
Strong Year-to-Date PerformanceThe fund has delivered strong gains so far this year, showing solid momentum in its strategy.
Leading Biotech and Pharma HoldingsSeveral top positions, including major biotech and pharmaceutical names, have shown strong or steady performance that supports the ETF’s overall returns.
Focused Exposure to Health Care InnovationWith most assets in the health care sector and U.S. companies, the fund gives targeted access to firms driving advances in biotechnology and medical research.
Negative Factors
High Sector ConcentrationThe ETF is heavily concentrated in health care, which increases risk if that sector faces a downturn.
Limited Geographic DiversificationWith the vast majority of holdings in U.S. companies, the fund offers little exposure to other regions and may be more sensitive to U.S.-specific risks.
Mixed Performance Among Top HoldingsA few of the largest positions have shown weak or negative performance, which can drag on the fund’s overall results despite its strong year-to-date gains.

WDNA vs. SPDR S&P 500 ETF (SPY)

AUM
5.02M
Region
Developed Markets
Expense Ratio
0.45%
Beta
0.92
Issuer
WisdomTree
Inception Date
Jun 03, 2021
Dividend Yield
3.13%
Asset Class
Equity
Index Tracked
WisdomTree BioRevolution Index

WDNA Summary

WDNA is an ETF that follows the WisdomTree BioRevolution Index, focusing on companies using genetics and biotechnology to change healthcare, agriculture, and other industries. It holds firms involved in gene editing, personalized medicine, and advanced lab tools, including well-known names like Eli Lilly and Moderna. Someone might invest in WDNA for growth potential and to get diversified exposure to many innovative biotech companies in a single fund. However, it is heavily focused on health care and biotech, so its price can be very volatile and may go up and down sharply with changes in the sector.

How much will it cost me?

This ETF has an expense ratio of 0.45%, which means you’ll pay about $4.50 per year for every $1,000 invested. That’s higher than the average low-cost index ETF because it’s a specialized, actively managed fund focused on cutting-edge genomics and biotechnology companies.

What would affect this ETF?

This ETF could benefit if breakthroughs in genomics and biotechnology lead to new successful drugs, wider use of personalized medicine, and supportive healthcare regulations in developed markets, helping companies like Eli Lilly, Moderna, and other top holdings grow. On the downside, it is heavily concentrated in health care, so setbacks like failed clinical trials, tighter drug pricing rules, or reduced funding for biotech research could hurt many of its holdings at the same time.

WDNA Top 10 Holdings

WDNA is essentially a bet on the BioRevolution, with heavyweight positions in Moderna and Twist Bioscience setting the tone. Both have been rising lately, giving the fund a strong push from the cutting edge of vaccines and synthetic DNA. 10x Genomics and Natera add more momentum in genomic tools and testing, while Tempus AI brings a data-driven twist to precision medicine. Blue-chip anchors like Eli Lilly and Johnson & Johnson are steadier, helping balance out more volatile names. The portfolio is heavily tilted toward U.S. healthcare and biotech, with little exposure beyond developed markets.

WDNA top ten holdings
NameCompany NameWeight %Market ValueMarket CapYearly GainOverall Rating
TWSTTWSTTwist Bioscience4.04%$208.49K$11.42B416.68%43Neutral
LLYLLYEli Lilly & Co3.24%$167.48K$1.21T57.09%72Outperform
TEMTEMTempus AI, Inc. Class A3.53%$182.41K$13.96B-11.53%52Neutral
NTRANTRANatera3.05%$157.46K$61.18B123.89%73Outperform
IMNMIMNMImmunome2.75%$141.84K$2.21B14.46%63Neutral
MRNAMRNAModerna2.67%$138.14K$85.50B744.83%59Neutral
TMOTMOThermo Fisher2.44%$126.04K$260.36B26.28%72Outperform
TXGTXG10x Genomics2.53%$130.87K$10.89B526.84%60Neutral
UTHRUTHRUnited Therapeutics2.09%$107.91K$25.15B41.20%79Outperform
STOKSTOKStoke Therapeutics2.17%$111.95K$1.70B-16.50%70Outperform

WDNA Technical Analysis

Technical Analysis SentimentPositive
Last Price24.61

Price Trends

50DMA23.28Positive
100DMA21.61Positive
200DMA19.72Positive

Market Momentum

MACD0.18Negative
RSI62.23Neutral
STOCH87.09Negative

Evaluating momentum and price trends is crucial in ETF analysis to make informed investment decisions. For WDNA, the sentiment is Positive. The current price of 24.61 is above the 20-day moving average (MA) of 23.25, above the 50-day MA of 23.28, and above the 200-day MA of 19.72, indicating a bullish trend. The MACD of 0.18 indicates Negative momentum. The RSI at 62.23 is Neutral, neither overbought nor oversold. The STOCH value of 87.09 is Negative, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Positive sentiment for WDNA.

WDNA Peer Comparison

Comparison Results

WDNA against its peer funds
NamePricePrice TargetAUMExpense RatioOverall Rating
WDNAWDNA$24.61$23.00(-6.52% Downside)$5.02M0.45%58Neutral
AGNGAGNG$38.56$43.32(12.35% Upside)$93.25M0.50%64Neutral
WISEWISE$33.48$69.39(107.26% Upside)$23.49M0.35%57Neutral
FOWFFOWF$35.04$46.07(31.50% Upside)$14.85M0.49%70Neutral
IVEPIVEP$24.37$34.47(41.46% Upside)$14.44M0.75%70Outperform
SPAMSPAM$49.58$54.55(10.03% Upside)$7.51M0.35%64Neutral

Performance Comparison

-20%0%20%40%WDNAAGNGWISEFOWFIVEPSPAMNov '25Dec '25Jan '26Feb '26Mar '26Apr '26May '26Jun '26Jul '26Aug '26Sep '26Oct '26
WDNA and its peers over the selected period
Show on chartTickerCompany NamePriceChange% Change
WDNAWisdomTree BioRevolution Fund24.618.4051.87%
AGNGGlobal X Aging Population ETF38.564.9714.79%
WISEThemes Generative Artificial Intelligence ETF33.48-10.11-23.20%
FOWFPacer Solactive Whitney Future of Warfare ETF35.043.8812.45%
IVEPDan IVES Wedbush AI Power & Infrastructure ETF24.37-1.73-6.63%
SPAMThemes Cybersecurity ETF49.5815.2744.51%
Glossary
BuyAn ETF rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the ETF is likely to deliver higher returns compared to other ETFs in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldAn ETF rated as a "Hold" s expected to perform in line with the overall market or a specific benchmark. This rating indicates that the ETF is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellAn ETF rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the ETF may deliver lower returns compared to other ETFs in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
Disclaimer

This AI Analyst ETF Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in ETFs carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.