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HELX - ETF AI Analysis

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HELX

Franklin Genomic Advancements ETF (HELX)

Rating:62Neutral
Price Target:
HELX, the Franklin Genomic Advancements ETF, reflects a mixed but generally promising profile, driven by strong contributors like Krystal Biotech and United Therapeutics, which show solid financial performance, growth prospects, and supportive technical trends. However, holdings such as Twist Bioscience and Adaptive Biotechnologies face profitability, cash flow, and valuation challenges that weigh on the fund’s overall quality. The main risk factor is the fund’s focus on genomics and biotech companies, which can mean higher volatility and sensitivity to financial health, valuations, and regulatory outcomes across its holdings.
Positive Factors
Strong Recent Performance
The ETF has shown strong recent gains over the past month and quarter, indicating positive momentum in its strategy.
Leading Holdings Performing Well
Several of the largest positions, including Guardant Health, Ligand Pharma, and Twist Bioscience, have delivered strong year-to-date gains that support the fund’s returns.
Focused Exposure to Genomics and Health Care
With most assets in health care and genomic-related companies, the fund offers targeted exposure to a specialized growth area in the market.
Negative Factors
High Sector Concentration
Nearly all assets are in the health care sector, so the fund is heavily exposed to swings in one industry rather than being broadly diversified.
Top Holdings Carry Significant Weight
A small group of companies makes up a large share of the portfolio, which increases the impact if any of these stocks experience setbacks.
Moderate Expense Ratio
The fund’s expense ratio is not especially low, meaning fees could take a noticeable bite out of long-term returns compared with cheaper ETFs.

HELX vs. SPDR S&P 500 ETF (SPY)

HELX Summary

The Franklin Genomic Advancements ETF (HELX) focuses on companies working in genetic research and advanced healthcare, rather than tracking a traditional stock index. It invests mainly in U.S. health care and biotech firms involved in gene-based testing and treatments, including well-known names like Eli Lilly and Vertex Pharmaceuticals, along with smaller, fast-growing specialists. Someone might invest in HELX to seek long-term growth from the rise of personalized medicine and new genetic therapies, while also getting a mix of established and emerging companies. A key risk is that biotech and genomics stocks can be very volatile and may rise or fall sharply with news and market sentiment.
How much will it cost me?The Franklin Genomic Advancements ETF (HELX) has an expense ratio of 0.5%, meaning you’ll pay $5 per year for every $1,000 invested. This is higher than average because it is actively managed, focusing on a specialized niche in genomic advancements, which requires more research and expertise compared to passively managed funds.
What would affect this ETF?The Franklin Genomic Advancements ETF (HELX) could benefit from growing interest in personalized medicine and advancements in genetic research, as well as increased healthcare spending globally. However, it may face challenges from regulatory hurdles in biotechnology, potential setbacks in clinical trials, and broader economic pressures that could impact funding for innovation. Its heavy focus on healthcare and genomic advancements makes it sensitive to both breakthroughs and disruptions in this niche sector.

HELX Top 10 Holdings

HELX is essentially a genomic medicine play, with most of its firepower in health care names pushing the frontiers of DNA-driven diagnostics and therapies. Guardant Health and Natera have been steady to rising, acting as key engines for the fund as demand for precision oncology grows. Krystal Biotech and Ligand Pharma add more punch but have seen mixed, sometimes lagging, short-term moves as valuations look stretched. Adaptive Biotechnologies and BridgeBio are rising stars, helping performance but still wrestling with profitability. Overall, it’s a globally focused, highly concentrated bet on cutting-edge biotech rather than broad market stability.
Name
Company Name
Weight %
Market Value
Market Cap
Yearly Gain
Overall Rating
Guardant Health9.18%$2.99M$21.90B160.00%
61
Neutral
Natera8.50%$2.77M$47.24B103.19%
73
Outperform
Krystal Biotech5.57%$1.82M$10.11B142.50%
80
Outperform
Adaptive Biotechnologies4.49%$1.46M$4.08B105.08%
53
Neutral
Twist Bioscience4.22%$1.37M$9.27B446.25%
43
Neutral
Ligand Pharma4.12%$1.34M$5.59B76.34%
60
Neutral
BridgeBio Pharma3.47%$1.13M$15.85B64.52%
59
Neutral
United Therapeutics3.08%$1.00M$22.00B67.69%
79
Outperform
Travere Therapeutics2.98%$970.71K$6.15B284.23%
56
Neutral
Vertex Pharmaceuticals2.81%$914.97K$138.79B42.79%
78
Outperform

HELX Technical Analysis

Technical Analysis Sentiment
Positive
Last Price
Price Trends
50DMA
39.89
Positive
100DMA
37.00
Positive
200DMA
36.21
Positive
Market Momentum
MACD
1.04
Negative
RSI
66.45
Neutral
STOCH
90.18
Negative
Evaluating momentum and price trends is crucial in ETF analysis to make informed investment decisions. For HELX, the sentiment is Positive. The current price of undefined is equal to the 20-day moving average (MA) of 41.16, equal to the 50-day MA of 39.89, and equal to the 200-day MA of 36.21, indicating a bullish trend. The MACD of 1.04 indicates Negative momentum. The RSI at 66.45 is Neutral, neither overbought nor oversold. The STOCH value of 90.18 is Negative, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Positive sentiment for HELX.

HELX Peer Comparison

Comparison Results
Name
Price
Price Target
AUM
Expense Ratio
Overall Rating
$32.57M0.50%
62
Neutral
$99.48M1.00%
69
Neutral
$89.02M0.75%
72
Outperform
$87.50M0.50%
68
Neutral
$78.89M0.90%
63
Neutral
$1.58M0.35%
60
Neutral
Performance Comparison
Ticker
Company Name
Price
Change
% Change
HELX
Franklin Genomic Advancements ETF
43.42
13.87
46.94%
FFND
Future Fund Active ETF
FITZ
Fitz-Gerald Must Have Portfolio ETF
IQM
Franklin Intelligent Machines ETF
HECO
SPDR Galaxy Hedged Digital Asset Ecosystem ETF
GNMX
Corgi Genomics & Precision Medicine ETF
Glossary
BuyAn ETF rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the ETF is likely to deliver higher returns compared to other ETFs in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldAn ETF rated as a "Hold" s expected to perform in line with the overall market or a specific benchmark. This rating indicates that the ETF is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellAn ETF rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the ETF may deliver lower returns compared to other ETFs in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
DisclaimerThis AI Analyst ETF Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in ETFs carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: ―
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