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Zai Lab Ltd (ZLAB)
:ZLAB
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Zai Lab (ZLAB) AI Stock Analysis

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ZL

Zai Lab

(NASDAQ:ZLAB)

Rating:54Neutral
Price Target:
$35.00
▲(6.94%Upside)
Zai Lab's overall stock score is primarily influenced by its strong revenue growth and solid balance sheet, despite significant profitability and liquidity challenges. The optimistic earnings call and positive corporate events provide a supportive outlook. However, technical indicators and valuation remain concerns, contributing to a moderate overall score.
Positive Factors
Regulatory Approval
The positive FORTITUDE-101 data support ZLAB’s plan to submit for regulatory approval in China as soon as possible.
Revenue Potential
Bemarituzumab is seen as having a $500M+ potential in China, offering significant long-term growth opportunities.
Negative Factors
Competitive Pressure
The entry of more competitors is affecting Zai Lab's core product market.
Sales Decline
Efgartigimod sales experienced a month-over-month decline of 6.0%.

Zai Lab (ZLAB) vs. SPDR S&P 500 ETF (SPY)

Zai Lab Business Overview & Revenue Model

Company DescriptionZai Lab (ZLAB) is a biopharmaceutical company focused on the discovery, development, and commercialization of innovative medicines. The company primarily operates in the sectors of oncology, autoimmune disorders, and infectious diseases. Zai Lab builds a portfolio of proprietary and in-licensed drug candidates, aiming to address major unmet medical needs by introducing cutting-edge therapies to patients in China and globally.
How the Company Makes MoneyZai Lab makes money through the commercialization of its pharmaceutical products and drug candidates. The company generates revenue by obtaining regulatory approvals and subsequently marketing these drugs to healthcare providers, hospitals, and patients. Key revenue streams include sales of approved therapies in China and collaborations or licensing agreements with other pharmaceutical companies for the development and commercialization of drug candidates. Significant partnerships with global biopharmaceutical firms also contribute to its earnings by providing milestone and royalty payments.

Zai Lab Earnings Call Summary

Earnings Call Date:May 08, 2025
(Q1-2025)
|
% Change Since: 15.41%|
Next Earnings Date:Aug 07, 2025
Earnings Call Sentiment Positive
The earnings call reflected a generally positive outlook with strong revenue growth and promising pipeline developments. While there were some temporary challenges such as seasonal declines and inventory dynamics affecting VYVGART sales, the company remains optimistic about achieving its full-year targets.
Q1-2025 Updates
Positive Updates
Strong Revenue Growth
Total revenue grew 22% year-over-year to $106.5 million in the first quarter, driven by increased sales for VYVGART, ZEJULA, and NUZYRA.
Improved Operating Loss
Operating loss improved by 20% to $56.3 million and by 25% to $37.1 million on an adjusted basis.
Promising Pipeline Developments
ZL-1310 is on track for a potential FDA approval in 2027. ZL-6201 and ZL-1503 are expected to enter clinical trials this year.
Positive VYVGART Outlook
VYVGART sales are expected to outpace total revenue growth, driven by increased patient demand and expanded access.
Strong Financial Position
The company ended the quarter with a cash position of $857.3 million.
Negative Updates
Seasonal Decline in VYVGART Sales
First quarter sales reflected seasonal trends with a temporary decline in patients in January and February due to Chinese New Year.
Inventory Dynamics Affecting Sales
Inventory build in Q4 for VYVGART Hytrulo had a notable impact on reported sales growth.
Company Guidance
During Zai Lab's first quarter 2025 earnings call, the company reaffirmed its full-year revenue guidance of $560 million to $590 million, anticipating accelerating sales growth that would help achieve profitability by Q4 2025. The company highlighted its differentiated portfolio and strong business fundamentals, targeting $2 billion in revenue by 2028. Zai Lab's lead global asset, ZL-1310, is progressing with updated Phase I data expected at ASCO in June, aiming for potential FDA approval in 2027. The company reported a total revenue increase of 22% year-over-year to $106.5 million, with operating loss improved by 20% to $56.3 million. The adjusted operating loss, excluding non-cash items, improved by 25% to $37.1 million. Zai Lab ended the quarter with a cash position of $857.3 million and reiterated its focus on achieving quarter-over-quarter growth through the remainder of the year.

Zai Lab Financial Statement Overview

Summary
Zai Lab demonstrates strong revenue growth and efficient production, but faces significant profitability and liquidity challenges. The balance sheet is robust due to low leverage and substantial equity, but consistent operating losses threaten future stability. Addressing cash flow issues and improving profitability are crucial for sustainable growth.
Income Statement
45
Neutral
Zai Lab's revenue has shown consistent growth over the years, with a revenue growth rate of 7.8% from 2024 to TTM (Trailing-Twelve-Months). However, the company remains unprofitable, with negative net and EBIT margins, indicating ongoing operational challenges. The gross profit margin is relatively high at 63.4% for TTM, suggesting efficient production processes but overshadowed by larger operational losses.
Balance Sheet
60
Neutral
The company maintains a strong equity position with a high equity ratio of 69.1% in TTM, reflecting financial stability. The debt-to-equity ratio remains low at 0.24, indicating conservative leverage. However, declining stockholder equity and consistent net losses pose potential risks to long-term financial health.
Cash Flow
35
Negative
Zai Lab's cash flow position is concerning, with negative free cash flow and operating cash flow. The operating cash flow to net income ratio is positive, showing some alignment between cash flow and accounting profits, but the free cash flow to net income ratio is negative, highlighting liquidity challenges.
BreakdownDec 2024Dec 2023Dec 2022Dec 2021Dec 2020
Income Statement
Total Revenue398.99M266.72M215.04M144.31M48.96M
Gross Profit251.13M170.90M141.02M92.07M32.22M
EBITDA-234.57M-365.11M-384.66M-689.46M-262.96M
Net Income-257.10M-334.62M-481.99M-692.44M-298.16M
Balance Sheet
Total Assets1.19B1.04B1.22B1.61B1.30B
Cash, Cash Equivalents and Short-Term Investments779.67M806.45M1.01B1.41B1.19B
Total Debt153.47M15.15M20.39M15.54M18.60M
Total Liabilities344.86M240.18M174.54M230.00M128.29M
Stockholders Equity840.90M796.12M1.05B1.38B1.17B
Cash Flow
Free Cash Flow-276.39M-206.67M-392.63M-568.18M-226.72M
Operating Cash Flow-214.87M-198.18M-367.64M-549.23M-216.06M
Investing Cash Flow-375.19M-10.78M420.02M249.96M-554.83M
Financing Cash Flow349.89M-6.43M-1.73M820.20M1.13B

Zai Lab Technical Analysis

Technical Analysis Sentiment
Positive
Last Price32.73
Price Trends
50DMA
34.01
Positive
100DMA
33.78
Positive
200DMA
30.50
Positive
Market Momentum
MACD
-0.21
Positive
RSI
49.90
Neutral
STOCH
37.76
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For ZLAB, the sentiment is Positive. The current price of 32.73 is below the 20-day moving average (MA) of 35.76, below the 50-day MA of 34.01, and above the 200-day MA of 30.50, indicating a neutral trend. The MACD of -0.21 indicates Positive momentum. The RSI at 49.90 is Neutral, neither overbought nor oversold. The STOCH value of 37.76 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Positive sentiment for ZLAB.

Zai Lab Risk Analysis

Zai Lab disclosed 100 risk factors in its most recent earnings report. Zai Lab reported the most risks in the "Finance & Corporate" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

Zai Lab Peers Comparison

Overall Rating
UnderperformOutperform
Sector (46)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
78
Outperform
$4.89B24.5115.38%16.98%-17.76%
71
Outperform
$7.40B19.506.01%1.42%
68
Neutral
$3.85B7.6033.08%91.12%
SHSHC
65
Neutral
$3.30B131.415.88%2.78%-54.72%
54
Neutral
$3.70B-32.05%43.72%28.63%
RNRNA
53
Neutral
$4.05B-34.19%-17.87%-1.89%
46
Neutral
C$201.03M-3.36-23.14%2.62%20.76%-0.69%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
ZLAB
Zai Lab
35.19
16.61
89.40%
OPCH
Option Care Health
30.74
-0.49
-1.57%
PTCT
PTC Therapeutics
47.75
13.58
39.74%
ELAN
Elanco Animal Health
14.61
1.36
10.26%
RNA
Avidity Biosciences
31.70
-14.98
-32.09%
SHC
Sotera Health
11.38
-1.52
-11.78%

Zai Lab Corporate Events

Executive/Board ChangesShareholder MeetingsStock Buyback
Zai Lab Shareholders Approve Key Proposals at AGM
Positive
Jun 18, 2025

On June 18, 2025, Zai Lab Limited held its 2025 Annual General Meeting of Shareholders, where holders of more than one-tenth of all voting share capital participated. The meeting resulted in the approval of Proposals 1 to 11 and 13 to 14, including the re-election of directors and the appointment of KPMG as auditors. The shareholders also approved an advisory vote on executive compensation and authorized the board to issue and repurchase shares up to 10% of the total issued shares, reflecting strong shareholder support for the company’s governance and strategic initiatives.

The most recent analyst rating on (ZLAB) stock is a Buy with a $50.00 price target. To see the full list of analyst forecasts on Zai Lab stock, see the ZLAB Stock Forecast page.

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Jul 15, 2025