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Unicycive Therapeutics (UNCY) AI Stock Analysis

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UNCY

Unicycive Therapeutics

(NASDAQ:UNCY)

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Rating:45Neutral
Price Target:$3.50â–¼(-6.42% Downside)
Action:reiterated
Date:10/14/26

The score is primarily held down by weak financial performance (zero revenue, sizable losses, and ongoing cash burn), which outweighs balance-sheet improvements. Technicals also detract due to a clear downtrend despite oversold readings. Corporate events are mixed, with a constructive NDA resubmission offset by litigation risk, while valuation metrics offer limited support given continued unprofitability.

Positive Factors
Regulatory ProgressResubmission with a new FDA-rated manufacturing vendor directly addresses deficiencies cited in prior CRLs, while stability and bridging data support the revised filing. This improves regulatory execution and preserves a path toward commercialization, although approval is not assured.
Negative Factors
No Current RevenueThe absence of current revenue confirms that Unicycive remains dependent on successful development and eventual commercialization of its pipeline. Persistent large losses also show that the business has not yet demonstrated operating leverage, making future earnings highly contingent on regulatory and launch execution.

Unicycive Therapeutics (UNCY) vs. SPDR S&P 500 ETF (SPY)

-25%0%25%50%75%100%UNCY-15.77%SPY+11.79%Dec '25Jan '26Feb '26Mar '26Apr '26May '26Jun '26Jul '26Aug '26Sep '26Oct '26
Market Cap
$102.45M
Dividend Yield
―
Average Volume (3M)
896.53K
Price to Earnings (P/E)
-2.2
Beta (1Y)
1.60
Revenue Growth
―
EPS Growth
43.63%
Country
US
Employees
21
Sector
Healthcare
Sector Strength
51
Industry
Biotechnology

Unicycive Therapeutics Business Overview & Revenue Model

Company Description

Unicycive Therapeutics, Inc. is a U.S.-based biotechnology company dedicated to the creation of innovative treatments for kidney diseases. Its development pipeline includes Renazorb, a therapy for hyperphosphatemia in chronic kidney disease patients,...

Unicycive Therapeutics Financial Statement Overview

Summary

Financials are constrained by an early-stage, loss-making profile: TTM revenue is $0 with a large net loss (~$35.2M) and continued cash burn (TTM operating cash flow and free cash flow both about -$27.8M). The main offset is an improved and lightly levered balance sheet (only ~$0.7M debt vs ~$53.3M equity), but ongoing losses keep dilution/financing risk elevated.

Income Statement

18Very Negative

Balance Sheet

56Neutral

Cash Flow

24Negative
Financial statement breakdown
BreakdownTTMDec 2025Mar 2025Dec 2023Mar 2023Mar 2022
Income Statement
Total Revenue000675.00K951.00K0
Gross Profit-211.00K-572.00K0675.00K951.00K0
EBITDA-34.52M-25.91M-36.23M-30.18M-17.89M-9.38M
Net Income-35.22M-26.55M-36.73M-30.54M-18.06M-10.02M
Balance Sheet
Total Assets72.03M49.13M31.67M14.19M2.82M18.74M
Cash, Cash Equivalents and Short-Term Investments61.42M41.27M26.14M9.70M455.00K16.58M
Total Debt671.00K199.00K773.00K811.00K201.00K335.00K
Total Liabilities18.76M18.94M24.24M18.00M3.28M2.26M
Stockholders Equity53.27M30.20M7.43M-3.81M-466.00K16.48M
Cash Flow
Free Cash Flow-27.85M-31.34M-28.65M-18.30M-15.65M-5.80M
Operating Cash Flow-27.84M-31.32M-28.57M-18.28M-15.65M-5.77M
Investing Cash Flow-17.25M-12.10M-72.00K-12.00K-2,000-29.00K
Financing Cash Flow66.95M46.47M45.09M27.54M-471.00K22.38M

Unicycive Therapeutics Technical Analysis

Technical Analysis SentimentNegative
Last Price3.74

Price Trends

50DMA4.54Negative
100DMA5.20Negative
200DMA6.10Negative

Market Momentum

MACD-0.23Negative
RSI40.46Neutral
STOCH47.29Neutral

Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For UNCY, the sentiment is Negative. The current price of 3.74 is below the 20-day moving average (MA) of 3.84, below the 50-day MA of 4.54, and below the 200-day MA of 6.10, indicating a bearish trend. The MACD of -0.23 indicates Negative momentum. The RSI at 40.46 is Neutral, neither overbought nor oversold. The STOCH value of 47.29 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Negative sentiment for UNCY.

Unicycive Therapeutics Risk Analysis

Unicycive Therapeutics disclosed 56 risk factors in its most recent earnings report. Unicycive Therapeutics reported the most risks in the "Finance & Corporate" category.

Higher RiskSector Avg.Lower RiskFinance & CorporateTech & InnovationLegal & RegulatoryProductionAbility to SellMacro & Political
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy

Latest Risks Added

1 New Risk
1.We may engage in strategic transactions that could disrupt our business, cause dilution to our stockholders or reduce our financial resources.Q2, 2026

Unicycive Therapeutics Peers Comparison

Overall Rating

UnderperformOutperform
Sector (51)

Financial Indicators

UNCY against its peers
NameOverall RatingMarket CapP/E RatioROEDividend YieldRevenue GrowthEPS Growth
FBIOFBIO67Neutral$64.03M0.59103.52%―15.46%―
Sector *51Neutral$7.86B-0.30-43.30%2.27%22.53%-2.21%
CVMCVM49Neutral$24.27M-0.53-202.14%――73.69%
EQEQ46Neutral$86.87M-5.34-41.15%―-100.00%64.23%
UNCYUNCY45Neutral$104.18M-2.23-88.81%――43.63%
CBUSCBUS44Neutral$98.59M-0.78-320.60%―-10.30%84.17%

* Healthcare Sector Average

Performance Comparison

0%100%UNCYCVMFBIOCBUSEQDec '25Jan '26Feb '26Mar '26Apr '26May '26Jun '26Jul '26Aug '26Sep '26Oct '26
UNCY and its peers over the selected period
Show on chartTickerCompany NamePriceChange% Change
UNCYUnicycive Therapeutics, Inc.3.74-0.70-15.77%
CVMCel-sci1.38-5.71-80.54%
FBIOFortress Biotech Inc1.92-0.52-21.31%
CBUSCibus, Inc.1.29-0.15-10.42%
EQEquillium1.37-0.18-11.61%

Unicycive Therapeutics Corporate Events

Business Operations and StrategyProduct-Related AnnouncementsRegulatory Filings and Compliance

Unicycive Resubmits NDA for Kidney Disease Treatment

Positive
Sep 29, 2026

On September 29, 2026, Unicycive Therapeutics announced it had resubmitted its New Drug Application for oxylanthanum carbonate, an oral phosphate binder for hyperphosphatemia in chronic kidney disease patients on dialysis. The resubmission follows pr...

Business Operations and StrategyLegal Proceedings

Unicycive Faces New Securities Class Action Over NDA Disclosures

Negative
Sep 28, 2026

On September 3, 2026, a securities class action lawsuit was filed in the United States District Court for the Northern District of California against Unicycive Therapeutics, Inc. and certain executives, alleging violations of federal securities laws...

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.

Date of analysis: Oct 14, 2026