The earnings call was predominantly positive, with significant regulatory progress and promising clinical data on TSHA-102 for Rett syndrome. The company is financially stable with a reduced net loss and decreased R&D expenses, although there was an increase in general and administrative costs.
Company Guidance
During the Taysha Gene Therapies First Quarter 2025 earnings call, the company provided significant updates on their TSHA-102 gene therapy program for Rett syndrome. The company announced the completion of dosing for 10 patients in Part A of their REVEAL Phase 1/2 trials, with six patients receiving a high dose of TSHA-102. Encouragingly, TSHA-102 was generally well-tolerated across both high and low dose cohorts with no treatment-related serious adverse events or dose-limiting toxicities as of April 10, 2025. Taysha highlighted their alignment with the FDA on key elements of their pivotal Part B trial design, which eliminates the need for a formal end-of-phase meeting, potentially expediting study initiation. Financially, the company reported a net loss of $21.5 million for Q1 2025, with $116.6 million in cash reserves expected to support operations into Q4 2026. Overall, Taysha expressed confidence in the therapeutic potential of TSHA-102 and its path towards regulatory approval.
Progress in TSHA-102 Gene Therapy Program
Significant regulatory and clinical progress with TSHA-102 for Rett syndrome, including FDA alignment on pivotal trial design without the need for an end-of-phase meeting.
Positive Clinical Data
TSHA-102 has shown early clinical improvements and functional gains in pediatric, adolescent, and adult patients with Rett syndrome, which are unlikely in the untreated population.
Strong Financial Position
Taysha has $116.6 million in cash and cash equivalents, with cash resources expected to support operations into the fourth quarter of 2026.
Decreased R&D Expenses
Research and development expenses decreased by $5.1 million compared to the prior year, driven by reduced GMP batch activities.
Taysha Gene Therapies (TSHA) Earnings, Revenues Date & History
The upcoming earnings date is based on a company’s previous reporting, and may be updated when the actual date is announced
The table shows recent earnings report dates and whether the forecast was beat or missed. See the change in forecast and EPS from the previous year.
Beat
Missed
TSHA Earnings-Related Price Changes
Report Date
Price 1 Day Before
Price 1 Day After
Percentage Change
May 15, 2025
$2.37
$2.56
+8.02%
Feb 26, 2025
$1.70
$1.62
-4.71%
Nov 13, 2024
$2.21
$2.27
+2.71%
Aug 12, 2024
$2.09
$2.04
-2.39%
Earnings announcements can affect a stock’s price. This table shows the stock's price the day before and the day after recent earnings reports, including the percentage change.
FAQ
When does Taysha Gene Therapies (TSHA) report earnings?
Taysha Gene Therapies (TSHA) is schdueled to report earning on Aug 18, 2025, TBA Not Confirmed.
What is Taysha Gene Therapies (TSHA) earnings time?
Taysha Gene Therapies (TSHA) earnings time is at Aug 18, 2025, TBA Not Confirmed.
Where can I see when companies are reporting earnings?
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