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TransMedics Group Inc (TMDX)
NASDAQ:TMDX
US Market
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TransMedics Group (TMDX) AI Stock Analysis

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TMDX

TransMedics Group

(NASDAQ:TMDX)

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Neutral 69 (OpenAI - Gpt-5.6Sol)
Rating:69Neutral
Price Target:
$100.00
▲(8.44% Upside)
Action:Reiterated
Date:08/05/26
The score reflects strong fundamentals and demand momentum (rapid growth and improved profitability versus prior years) supported by a reasonable P/E. This is tempered by rising leverage and weaker recent free-cash-flow conversion, plus guidance that implies near-term margin pressure and execution risk from heavy investment and PAD-related dilution. Technicals are mixed, with improving short-term trend but still weak longer-term trend.
Positive Factors
Sustained Revenue Growth
Raised guidance and record quarterly revenue indicate continued adoption of the OCS platform and related services. Growth is supported by product utilization, logistics expansion and multiple organ-specific opportunities.
Negative Factors
Margin Compression
Lower margin guidance signals that accelerated investment, service mix and cost pressures will weigh on profitability beyond a single quarter. Sustained spending could delay operating leverage even as revenue continues to grow.
Read all positive and negative factors
Positive Factors
Negative Factors
Sustained Revenue Growth
Raised guidance and record quarterly revenue indicate continued adoption of the OCS platform and related services. Growth is supported by product utilization, logistics expansion and multiple organ-specific opportunities.
Read all positive factors

TransMedics Group Key Performance Indicators (KPIs)

Any
Any
Revenue by Geography
Revenue by Geography
Divides revenue by market to show geographic strengths and vulnerabilities. Expansion into multiple transplant hubs points to scalable adoption and reduced reliance on any single region, while heavy dependence on one area increases risk from regulatory, reimbursement, or economic changes there.
Chart InsightsInternational revenue has moved from a tiny base to clear acceleration, hitting fresh highs but with pronounced quarter-to-quarter lumpiness. Management frames this as early-stage traction tied to European NOP expansion, tenders and a PAD Aviation partnership—signaling meaningful upside if reimbursement and rollouts go smoothly—but also material timing and volatility risk; international can boost growth but won’t immediately stabilize margins or replace core U.S. transplant revenue.
Data provided by:The Fly

TransMedics Group (TMDX) vs. SPDR S&P 500 ETF (SPY)

TransMedics Group Business Overview & Revenue Model

Company Description
TransMedics Group, Inc. operates as a commercial-stage medical technology enterprise, committed to transforming the landscape of organ transplant therapy for patients worldwide grappling with end-stage organ failure. At the core of their offerings...
How the Company Makes Money
TransMedics primarily generates revenue by selling and supporting its OCS platform and by charging for services associated with using the technology in real-world transplant workflows. Key revenue streams include: (1) product revenue from the sale...

TransMedics Group Earnings Call Summary

Earnings Call Date:Aug 04, 2026
(Q2-2026)
|
% Change Since: |
Next Earnings Date:Nov 04, 2026
Earnings Call Sentiment Positive
The call presented a predominantly positive operational and commercial picture: record revenue, strong product and service growth (notably liver and logistics), improved sequential gross margin, robust cash balance, and raised revenue guidance. At the same time, the company is investing heavily in strategic initiatives (OCS Kidney, Gen 3.0, ENHANCE, DENOVO, European logistics/PAD) which is elevating R&D and operating expenses, tempering near-term operating margin and introducing execution and timing risk (IDE approvals, PAD integration and international reimbursement). Overall, the fundamentals and long-term growth roadmap are strong, but near-term profitability will be impacted by deliberate, front-loaded investments and some timing uncertainties.
Positive Updates
Record Quarterly Revenue and Volume
Total revenue of approximately $190 million, the highest quarterly revenue in company history, up ~21% year-over-year and ~9% sequentially.
Negative Updates
Near-Term Margin Pressure from Mix and Costs
Total gross margin declined ~180 basis points year-over-year (despite sequential improvement) due to higher mix of service revenue and temporary product cost pressures including inventory provisioning and trial-related solution costs.
Read all updates
Q2-2026 Updates
Negative
Record Quarterly Revenue and Volume
Total revenue of approximately $190 million, the highest quarterly revenue in company history, up ~21% year-over-year and ~9% sequentially.
Read all positive updates
Company Guidance
TransMedics raised the low end of its 2026 revenue guide to $737–$757 million (≈22%–25% growth vs. 2025), explicitly assuming no revenue from the recent PAD Aviation investment and no meaningful contribution yet from ENHANCE Part B or DENOVO; management expects second-half gross margin (ex‑PAD) of ~59% and a full‑year adjusted operating margin (ex‑PAD) of ~12.5%–14% (vs. a prior ~16% target and 2025’s 18.5%), with Q2 adjusted operating margin at 13.6% (~$25.8M) and adjusted net income of $16.2M ($0.44 diluted EPS on ~40.7M shares). The company finished Q2 with ~$473M cash (+~$18M restricted), forecasts full‑year interest expense of ~ $29M (including ~$15.3M HQ‑related) partially offset by ~ $12M interest income, expects an effective tax rate of ~26% for the year, warns PAD consolidation in Q3 will be near‑term dilutive to gross and operating margins, and reiterates longer‑term targets of ~60% sustainable gross margin and a platform capable of ~30,000 transplants by 2032 driving >$2B in annual revenue.

TransMedics Group Financial Statement Overview

Summary
Strong multi-year revenue growth and a clear transition to profitability with solid gross margin (~59%). Offsetting this, TTM profitability has stepped down (operating and net margins down), leverage is rising (debt-to-equity ~1.6), and free cash flow fell sharply TTM (~48% decline), which reduces financial flexibility if margins remain pressured.
Income Statement
82
Very Positive
Balance Sheet
58
Neutral
Cash Flow
63
Positive
BreakdownTTMDec 2025Dec 2024Dec 2023Dec 2022Dec 2021
Income Statement
Total Revenue668.47M605.49M441.54M241.62M93.46M30.26M
Gross Profit392.35M362.81M262.08M154.09M65.27M21.16M
EBITDA119.97M148.49M69.95M-7.70M-28.96M-38.49M
Net Income151.70M190.29M35.46M-25.03M-36.23M-44.22M
Balance Sheet
Total Assets1.46B1.07B804.08M706.05M277.15M134.89M
Cash, Cash Equivalents and Short-Term Investments472.68M488.37M336.65M394.81M201.18M92.45M
Total Debt867.72M469.69M518.29M515.95M67.56M43.80M
Total Liabilities946.34M595.27M575.47M568.85M89.77M67.04M
Stockholders Equity518.05M473.10M228.60M137.20M187.38M67.85M
Cash Flow
Free Cash Flow79.04M133.59M-80.94M-192.09M-57.72M-32.38M
Operating Cash Flow145.93M192.84M48.80M-13.03M-45.82M-28.86M
Investing Cash Flow-66.89M-59.25M-129.30M-193.95M54.51M29.27M
Financing Cash Flow11.47M16.86M22.87M400.42M167.93M1.39M

TransMedics Group Technical Analysis

Technical Analysis Sentiment
Positive
Last Price92.22
Price Trends
50DMA
78.93
Positive
100DMA
82.30
Positive
200DMA
105.71
Negative
Market Momentum
MACD
4.36
Negative
RSI
61.38
Neutral
STOCH
68.30
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For TMDX, the sentiment is Positive. The current price of 92.22 is above the 20-day moving average (MA) of 87.61, above the 50-day MA of 78.93, and below the 200-day MA of 105.71, indicating a neutral trend. The MACD of 4.36 indicates Negative momentum. The RSI at 61.38 is Neutral, neither overbought nor oversold. The STOCH value of 68.30 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Positive sentiment for TMDX.

TransMedics Group Risk Analysis

TransMedics Group disclosed 75 risk factors in its most recent earnings report. TransMedics Group reported the most risks in the "Finance & Corporate" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

TransMedics Group Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
78
Outperform
$1.79B13.0517.62%4.35%161.83%
69
Neutral
$3.20B20.7632.97%25.82%108.84%
69
Neutral
$4.41B23.2015.41%12.39%
67
Neutral
$4.26B33.967.43%2.62%53.15%
63
Neutral
$1.45B-13.29-818.99%19.47%36.87%
61
Neutral
$10.65B-55.97-27.07%41.55%-96.75%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
TMDX
TransMedics Group
91.75
-24.97
-21.39%
ATEC
Alphatec Holdings
9.57
-6.46
-40.30%
ITGR
Integer Holdings
125.30
17.92
16.69%
GKOS
Glaukos
181.91
85.35
88.39%
LIVN
LivaNova
80.03
24.58
44.33%
INSP
Inspire Medical Systems
60.82
-30.64
-33.50%
Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Aug 05, 2026