TipRanks
Spyre Therapeutics (SYRE)
NASDAQ:SYRE
US Market
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Spyre Therapeutics (SYRE) Ownership - Who Owns Spyre Therapeutics?

578 Followers

Spyre Therapeutics (SYRE) Ownership Overview

1.73%22.54%46.51%15.41%13.82%
46.51% Other Institutional Investors
15.41% ETFs
13.82% Public Companies and
Individual Investors
The ownership structure of Spyre Therapeutics (SYRE) stock is a mix of institutional, retail, and individual investors. Approximately 84.45% of the company’s stock is owned by Institutional Investors, 1.73% is owned by Insiders, and 13.82% is owned by Public Companies and Individual Investors.
The ownership structure of Spyre Therapeutics (SYRE) stock is a mix of institutional, retail, and individual investors. Approximately 69.05% of the company’s stock is owned by Institutional Investors, 1.73% is owned by Insiders, and 15.41% is owned by Public Companies and Individual Investors.

Recent Insider Trading Activity

Date
Name
Activity
Value
Jun 26, 2026
xxxxxxxxxxxxx
$1307000
Jun 23, 2026
xxxxxxxxxxxxx
$399658667
Sep 03, 2025
xxxxxxxxxxxxx
$299639

Recent Hedge Fund Trading Activity

Date
Firm
Activity
Value
Jun 30, 2026
xxxxxxxxxxxxx
$383484855
Jun 30, 2026
xxxxxxxxxxxxx
$248509957
Jun 30, 2026
xxxxxxxxxxxxx
$10669314
Jun 30, 2026
xxxxxxxxxxxxx
$27171030

Top Shareholders

Holder
# of Shares
Type
% Holding
Value
5,647,118Institution6.40%502,762,916
4,319,496Institution4.90%384,564,729
4,018,101Institution4.56%357,731,532
3,744,062Institution4.25%333,333,840
3,532,143Institution4.01%314,466,691
2,979,341Institution3.38%265,250,729
2,799,166Institution3.17%249,209,749
2,412,693Institution2.74%214,802,058
2,013,252Institution2.28%179,239,826
1,701,157Institution1.93%151,454,008

Top Mutual Fund Holders

Holder
# of Shares
Type
% Holding
Value
3,532,143Institution4.01%314,466,691
2,979,341Institution3.38%265,250,729
2,412,693Institution2.74%214,802,058
1,701,157Institution1.93%151,454,008
1,341,953Institution1.52%119,474,076
1,261,772Institution1.43%112,335,561
854,145Institution0.97%76,044,529
811,882Institution0.92%72,281,854
750,263Institution0.85%66,795,915
479,383Institution0.54%42,679,468

Top ETF Holders

Holder
# of Shares
Type
% Holding
Value
2,487,614Institution2.82%222,218,559
1,998,572Institution2.27%177,932,865
1,743,463Institution1.98%147,706,185
927,160Institution1.05%82,823,203
898,097Institution1.02%80,227,005
716,017Institution0.81%63,746,994
621,200Institution0.70%55,305,436
571,025Institution0.65%51,009,663
436,201Institution0.49%36,954,949
428,080Institution0.49%38,240,386

FAQ

Who Owns Spyre Therapeutics (SYRE)?
According to the latest TipRanks data, approximately 46.51% of the company's stock is held by institutional investors, 1.73% is held by insiders, and 13.82% is held by retail investors.
    What percentage of Spyre Therapeutics (SYRE) stock is held by institutional investors?
    According to the latest TipRanks data, approximately 46.51% of Spyre Therapeutics (SYRE) stock is held by institutional investors.
      What percentage of Spyre Therapeutics (SYRE) stock is held by retail investors?
      According to the latest TipRanks data, approximately 13.82% of Spyre Therapeutics (SYRE) stock is held by retail investors.
        Who owns the most shares of Spyre Therapeutics (SYRE)?
        Vanguard owns the most shares of Spyre Therapeutics (SYRE).
          What is the significance of the ownership structure for a publicly traded company?
          The ownership structure can impact the company's decision making, as large institutional investors may exert influence on the company's management and can also affect the company's stock price with their buying and selling patterns.