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ETFs with Spyre Therapeutics (SYRE) Exposure

The following ETFs maintain exposure to Spyre Therapeutics (SYRE). ETF holdings data are updated periodically, based on the latest holdings the ETFs report, and are subject to change. To see a complete breakdown of any of the ETFs included in the table below, including asset class, AUM, and country allocations, click on the ticker symbol.

127 ETFs Hold Spyre Therapeutics (SYRE)

ETFs holding SYRE
SymbolETF NameAUMExpense Ratio% Weight in ETFMarket Value% Weight in SYRE
LFSCF/M Emerald Life Sciences Innovation ETF$125.43M0.54%4.10%$5.14M0.06%
QMOMAlpha Architect U.S. Quantitative Momentum ETF$424.93M0.28%2.34%$9.96M0.11%
TDNAT. Rowe Price Biotech ETF$11.32M0.55%1.98%$224.34K<0.01%
XBISPDR S&P BIOTECH ETF$11.05B0.35%1.64%$175.75M1.92%
FCMOFidelity US Momentum Index ETF Series L Trust Units$2.58B0.38%1.18%$29.19M0.26%
MMSCFirst Trust Multi-Manager Small Cap Opportunities ETF$53.09M0.95%1.13%$583.51K<0.01%
SGRWHarbor Active Small Cap Growth ETF$28.11M0.80%1.07%$301.04K<0.01%
W311HANetf ICAV - HAN-GINS Indxx Healthcare Megatrend Equal Weight UCITS ETF Accum-USD-$14.14M0.89%1.01%$143.39K<0.01%
BBCVirtus LifeSci Biotech Clinical Trials ETF$35.24M0.65%0.93%$319.32K<0.01%
DWASInvesco DWA SmallCap Momentum ETF$397.64M0.60%0.83%$3.23M0.04%
MEDIHarbor Health Care ETF$45.93M0.80%0.73%$336.66K<0.01%
USMIDFranklin ClearBridge US Smaller Companies UCITS ETF AccumUSD―0.54%0.70%$37.60K<0.01%
GSCGoldman Sachs Small Cap Core Equity ETF$307.56M0.75%0.67%$2.02M0.02%
ESSCEventide Small Cap ETF$34.73M0.49%0.57%$193.70K<0.01%
OM3EiShares NASDAQ US Biotechnology UCITS ETF$78.53M0.37%0.56%$7.40M0.08%
IBBQInvesco Nasdaq Biotechnology ETF$120.43M0.19%0.54%$651.39K<0.01%
GDOCGoldman Sachs Future Health Care Equity ETF$20.51M0.75%0.54%$110.75K<0.01%
IBBiShares Biotechnology ETF$11.52B0.44%0.52%$59.59M0.67%
ACSGAmerican Century Small Cap Growth Insights ETF$54.55M0.49%0.51%$276.89K<0.01%
FTXHFirst Trust Nasdaq Pharmaceuticals ETF$1.18B0.60%0.50%$5.98M0.07%
IWOiShares Russell 2000 Growth ETF$14.31B0.24%0.50%$69.71M0.78%
JDOCJPMorgan Healthcare Leaders ETF$9.78M0.65%0.50%$48.69K<0.01%
FMEDFidelity Disruptive Medicine ETF$54.39M0.50%0.49%$267.19K<0.01%
FDMOFidelity Momentum Factor ETF$842.60M0.15%0.47%$3.99M0.04%
SCDSJPMorgan Fundamental Data Science Small Core ETF$9.57M0.40%0.47%$45.32K<0.01%
FSMLFranklin Small Cap Enhanced ETF$153.75M0.45%0.47%$710.68K<0.01%
VTWGVanguard Russell 2000 Growth ETF$1.44B0.06%0.44%$7.41M0.09%
CGMMCapital Group U.S. Small and Mid Cap ETF$3.67B0.51%0.41%$14.95M0.16%
ACSMHartford Alpha Capture SMID Cap ETF$20.39M0.52%0.39%$63.33K<0.01%
PWSPacer WealthShield ETF$14.55M0.60%0.33%$47.90K<0.01%
IQSMIQ Candriam ESG U.S. Mid Cap Equity ETF$433.95M0.15%0.31%$1.33M0.01%
BBSCJPMorgan BetaBuilders U.S. Small Cap Equity ETF$751.21M0.09%0.31%$2.32M0.03%
FTKIFirst Trust Small Cap BuyWrite Income ETF$25.61M0.86%0.29%$72.52K<0.01%
TNXTT. Rowe Price Innovation Leaders ETF$19.28M0.49%0.28%$53.83K<0.01%
RESMColumbia Research Enhanced Small Cap ETF$5.96M0.32%0.25%$15.14K<0.01%
RTYSInvesco Russell 2000 UCITS ETF$318.41M0.25%0.25%$804.10K<0.01%
IWMiShares Russell 2000 ETF$76.76B0.19%0.25%$192.60M2.11%
R2EHState Street SPDR RUSSELL 2000 U.S. SMALL CAP UCITS ETF Accum Shs - Hedged EUR$148.28M0.46%0.25%$12.31M0.13%
RSSLGlobal X Russell 2000 ETF$1.47B0.08%0.25%$3.67M0.04%
RUSCUS Small Cap Equity Active ETF$85.25M0.64%0.25%$197.36K<0.01%
TSEET. Rowe Price Small Cap ETF$10.71M0.59%0.25%$26.62K<0.01%
MSSMMorgan Stanley Pathway Small-Mid Cap Equity ETF$708.38M0.62%0.24%$1.67M0.02%
ITWOProShares Russell 2000 High Income ETF$182.44M0.55%0.23%$427.21K<0.01%
VRSDVanguard Russell 2000 U.S. Small-Cap UCITS ETF USD$2.24M―0.23%$32.50K<0.01%
VTWOVanguard Russell 2000 ETF$17.04B0.06%0.22%$39.56M0.48%
RBProShares Russell 2000 Dynamic Buffer ETF$1.17M0.58%0.22%$2,572.96<0.01%
VFMOVanguard U.S. Momentum Factor ETF$1.93B0.13%0.20%$3.88M0.04%
USVMVictoryShares USAA MSCI USA Small Cap Value Momentum ETF$1.86B0.29%0.20%$3.72M0.04%
SCHASchwab U.S. Small-Cap ETF$22.39B0.03%0.19%$43.47M0.48%
BKMCBNY Mellon US Mid Cap Core Equity ETF$655.88M0.04%0.18%$1.18M0.01%
PJSMPGIM Jennison Small-Mid Cap Core Equity ETF$6.04M0.29%0.18%$11.48K<0.01%
GSSCGoldman Sachs Activebeta U.S. Small Cap Equity ETF$1.08B0.20%0.18%$1.86M0.02%
VBRVanguard Small Cap Value ETF$37.27B0.05%0.17%$109.24M1.33%
SCHMSchwab U.S. Mid-Cap ETF$14.98B0.03%0.17%$24.82M0.27%
ISCViShares Morningstar Small Cap Value ETF$694.47M0.06%0.16%$1.09M0.01%
TMSLT. Rowe Price Small-Mid Cap ETF$3.21B0.55%0.16%$5.02M0.05%
VMOVanguard GlbMomntFac$490.96M0.44%0.11%$567.94K<0.01%
JPSCBetaBuilders US Small Cap Equity UCITS ETF AccumUSD$93.36M0.14%0.11%$418.39K<0.01%
BBSDBetaBuilders US Small Cap Equity UCITS ETF USD$264.21M0.14%0.11%$418.39K<0.01%
JGUDJPM Active US Growth UCITS ETF Unhedged USD$1.13M0.50%0.10%$699.63K<0.01%
JGROJPM Active US Growth UCITS ETF Unhedged USD$708.70M0.50%0.10%$699.63K<0.01%
JGEHJPM Active US Growth UCITS ETF Hedged EUR$5.92M0.50%0.10%$699.63K<0.01%
ESMLiShares ESG Aware MSCI USA Small-Cap ETF$2.77B0.17%0.10%$2.74M0.03%
JGROJPMorgan Active Growth ETF$9.76B0.44%0.10%$9.67M0.11%
JGROJPMorgan US Growth Active ETF Trust Units$52.04M0.51%0.10%$51.23K<0.01%
VBVanguard Small-Cap ETF$79.87B0.03%0.09%$167.78M2.04%
USSMBNP Paribas Easy MSCI USA Small Cap Min Te UCITS ETF Accum-CAP- EUR$30.68M0.30%0.09%$76.17K<0.01%
USSMBNP Paribas Easy MSCI USA Small Cap Min Te UCITS ETF AccumUSD$47.20M0.31%0.09%$76.17K<0.01%
MSMLiShares MSCI USA Small-Cap ETF$279.43M0.04%0.09%$258.19K<0.01%
ISCGiShares Morningstar Small-Cap Growth ETF$981.82M0.06%0.09%$869.43K<0.01%
SMLFiShares MSCI USA Small-Cap Multifactor ETF$4.28B0.15%0.09%$3.84M0.04%
VXFVanguard Extended Market ETF$30.86B0.05%0.09%$83.18M1.01%
FHLCFidelity MSCI Health Care Index ETF$3.95B0.08%0.08%$3.08M0.03%
VHTVanguard Health Care ETF$20.70B0.09%0.08%$16.66M0.20%
VSMLVanguard FTSE Global Small-Cap UCITS ETF Accun USD$44.32M0.25%0.06%$27.51K<0.01%
VSMDVanguard Funds plc - Vanguard FTSE Global Small-Cap UCITS ETF$12.34M0.25%0.06%$27.51K<0.01%
PRFZInvesco FTSE RAFI US 1500 Small-Mid ETF$2.71B0.36%0.06%$1.67M0.02%
AVIEAvantis Inflation Focused Equity ETF$16.72M0.25%0.06%$10.39K<0.01%
XMEMdbxt MSCI EM Shs -1C- Capitalisation$958.44M0.12%0.06%$696.06K<0.01%
XMCMXtrackers MSCI Emerging Markets Swap UCITS ETF$214.01M0.12%0.06%$696.06K<0.01%
WRDSCUBS (Irl) ETF PLC - UBS MSCI World Small Cap UCITS ETF$46.10M0.23%0.06%$26.94K<0.01%
WSMLiShares MSCI World Small-Cap ETF$668.76M0.30%0.06%$381.51K<0.01%
XSWDXtrackers MSCI World Small Cap UCITS ETF -1D- USD$17.11M0.25%0.06%$100.44K<0.01%
XSWCXtrackers MSCI World Small Cap UCITS ETF Accum-1C- USD$157.24M0.25%0.06%$100.44K<0.01%
SMMViShares MSCI USA Small-Cap Min Vol Factor ETF$278.80M0.20%0.06%$154.98K<0.01%
DFMCU.S. Micro Cap Portfolio ETF$211.48M0.41%0.05%$4.54M0.05%
WDSCSSga II Wrd Sma Accum.Shs USD$1.69B0.46%0.05%$930.03K0.01%
WSCDSPDR MSCI World Small Cap UCITS ETF USD$52.03M0.46%0.05%$930.03K0.01%
CBUGiShares MSCI World Small Cap ESG Enhanced UCITS ETF USD$484.34M0.38%0.05%$250.57K<0.01%
WMSCAmundi MSCI World Small Cap ESG Broad Transition UCITS ETF Accum USD$550.73M0.27%0.05%$278.30K<0.01%
PTLInspire 500 ETF$888.20M0.09%0.05%$438.77K<0.01%
HDGProShares Hedge Replication ETF$22.40M0.95%0.04%$9,203.28<0.01%
MUMC.BManulife Multifactor U.S. Mid Cap Index ETF$78.09M0.57%0.04%$41.40K<0.01%
MUMCManulife Multifactor U.S. Mid Cap Index ETF Hedged$23.66M0.62%0.04%$41.40K<0.01%
JHMMJohn Hancock Multifactor Mid Cap ETF$6.12B0.41%0.04%$2.44M0.03%
IQSCInvesco Global Small Cap Enhanced Equity UCITS ETF Accum- USD$4.07M―0.03%$1,158.72<0.01%
FFSMFidelity Fundamental Small-Mid Cap ETF$1.51B0.43%0.03%$409.49K<0.01%
ONEQFidelity Nasdaq Composite Index ETF$10.76B0.21%0.02%$2.20M0.02%
TILTFlexShares Morningstar US Market Factor Tilt Index Fund$2.22B0.25%0.02%$414.25K<0.01%
UEQEUBS (Irl) ETF Plc - MSCI USA Select Factor Mix UCITS ETF$32.83M0.25%0.02%$32.39K<0.01%
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SYRE ETF Exposure FAQ

What ETFs hold Spyre Therapeutics stock?
Spyre Therapeutics (SYRE) is currently held by 127 ETFs in TipRanks’ ETF exposure database. The ETF(s) with exposure to SYRE include SPDR (XBI), Fidelity (TSE:FCMO) and Alpha Architect (QMOM).
Which ETF has the largest exposure to SYRE?
The ETF with the largest exposure to SYRE is SPDR (XBI), with approximately $175.75M in market value exposure.
How much SYRE stock is held by ETFs?
ETFs currently hold approximately $224.84M worth of Spyre Therapeutics (SYRE) stock, based on TipRanks’ ETF exposure data.
How often is ETF exposure data updated?
ETF exposure data is updated periodically based on the latest available ETF holdings and reporting data. Actual ETF positions may change between reporting periods.