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Senti Biosciences
(NASDAQ:SNTI)
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Rating:42Neutral
Price Target:
$0.37
▼(-4.62% Downside)
Action:Reiterated
Date:08/22/26
Overall score is driven primarily by weak financial performance: minimal revenue, large ongoing losses, heavy cash burn, and a notably stressed balance sheet with negative equity. Technicals add additional pressure due to a clear longer-term downtrend (price well below 50/100/200-day averages). Valuation provides limited support because a negative P/E reflects continued unprofitability and there is no dividend yield data.
Positive Factors
Debt Reduction
Lower absolute debt reduces scheduled financing pressure and may improve financial flexibility relative to prior periods. However, the benefit is constrained by negative equity, asset depletion, and continuing cash consumption.
Negative Factors
Minimal Revenue Scale
Revenue remains too small and inconsistent to absorb the company’s operating costs or demonstrate commercial traction. Until partnered programs produce more reliable funding or products reach approval, the business remains dependent on external financing and development milestones.
Read all positive and negative factors
Positive Factors
Negative Factors
Debt Reduction
Lower absolute debt reduces scheduled financing pressure and may improve financial flexibility relative to prior periods. However, the benefit is constrained by negative equity, asset depletion, and continuing cash consumption.
Read all positive factors
Senti Biosciences (SNTI) vs. SPDR S&P 500 ETF (SPY)
Market Cap
$10.62M
Dividend YieldN/A
Average Volume (3M)209.42K
Price to Earnings (P/E)―
Beta (1Y)1.75
Revenue GrowthN/A
EPS Growth80.28%
CountryUS
Employees39
SectorHealthcare
Sector Strength45
IndustryBiotechnology
Share Statistics
EPS (TTM)-1.77
Shares Outstanding31,144,754
10 Day Avg. Volume223,177
30 Day Avg. Volume209,423
Financial Highlights & Ratios
PEG Ratio<0.01
Price to Book (P/B)41.84
Price to Sales (P/S)10628.51
P/FCF Ratio-5.36
Enterprise Value/Market Cap<0.01
Enterprise Value/Revenue<0.01
Enterprise Value/Gross Profit>-0.01
Enterprise Value/Ebitda>-0.01
Forecast
1Y Price TargetN/A
Price Target UpsideN/A
Rating ConsensusN/A
Number of Analyst Covering0
EPS Forecast (FY)-1.05
Revenue Forecast (FY)$58.00K
Senti Biosciences Business Overview & Revenue Model
Company Description
Senti Biosciences, Inc. is a pioneering company specializing in gene circuit technology. They focus on creating advanced cell and gene therapies that incorporate sophisticated gene circuits, essentially biological computers, to genetically reprogr...
How the Company Makes Money
Senti Biosciences generates revenue primarily through collaboration and licensing arrangements related to its cell-therapy engineering platforms and product candidates, which may include upfront payments, research funding or cost reimbursements, m...
Senti Biosciences Financial Statement Overview
Summary
Income Statement
12
Very Negative
Balance Sheet
28
Negative
Cash Flow
22
Negative
| Breakdown | TTM | Dec 2025 | Dec 2024 | Dec 2023 | Dec 2022 | Dec 2021 |
|---|---|---|---|---|---|---|
Income Statement | ||||||
| Total Revenue | 55.00K | 22.00K | 0.00 | 1.98M | 3.29M | 2.29M |
| Gross Profit | -1.50M | -3.62M | 0.00 | 1.98M | 3.29M | 2.29M |
| EBITDA | -47.20M | -57.80M | -54.88M | -61.34M | -45.74M | -52.31M |
| Net Income | -49.56M | -61.44M | -52.79M | -71.06M | -58.21M | -55.32M |
Balance Sheet | ||||||
| Total Assets | 33.10M | 51.22M | 97.84M | 119.48M | 180.79M | 96.70M |
| Cash, Cash Equivalents and Short-Term Investments | 6.46M | 16.42M | 48.28M | 35.93M | 98.56M | 56.03M |
| Total Debt | 20.23M | 28.89M | 33.64M | 37.67M | 37.09M | 22.73M |
| Total Liabilities | 36.51M | 45.63M | 72.19M | 52.57M | 53.53M | 36.33M |
| Stockholders Equity | -3.40M | 5.59M | 25.65M | 66.91M | 127.26M | 60.38M |
Cash Flow | ||||||
| Free Cash Flow | -38.05M | -43.64M | -41.42M | -64.43M | -76.27M | -40.18M |
| Operating Cash Flow | -38.05M | -43.44M | -41.40M | -52.40M | -34.90M | -34.63M |
| Investing Cash Flow | 126.00K | -184.00K | 34.00K | 30.08M | -81.96M | -5.54M |
| Financing Cash Flow | 20.72M | 11.76M | 53.73M | 779.00K | 118.55M | 68.44M |
Senti Biosciences Technical Analysis
Negative
0.39
Price Trends
0.55
Negative
0.77
Negative
0.96
Negative
Market Momentum
-0.05
Negative
30.75
Neutral
7.69
Positive
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For SNTI, the sentiment is Negative. The current price of 0.39 is above the 20-day moving average (MA) of 0.39, below the 50-day MA of 0.55, and below the 200-day MA of 0.96, indicating a bearish trend. The MACD of -0.05 indicates Negative momentum. The RSI at 30.75 is Neutral, neither overbought nor oversold. The STOCH value of 7.69 is Positive, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Negative sentiment for SNTI.
Senti Biosciences Risk Analysis
Senti Biosciences disclosed 116 risk factors in its most recent earnings report. Senti Biosciences reported the most risks in the "Finance & Corporate" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks
Senti Biosciences Peers Comparison
UnderperformOutperform
Sector (51)
Name | Overall Rating | Market Cap | P/E Ratio | ROE | Dividend Yield | Revenue Growth | EPS Growth |
|---|---|---|---|---|---|---|---|
51 Neutral | $7.86B | -0.30 | -43.30% | 2.27% | 22.53% | -2.21% | |
49 Neutral | $29.39M | -0.74 | -59.18% | ― | -100.00% | 41.21% | |
44 Neutral | $40.15M | -0.08 | 77.63% | ― | 6.81% | 11.95% | |
44 Neutral | $24.68M | -0.68 | -145.40% | ― | -100.00% | 82.57% | |
42 Neutral | $10.62M | -0.19 | -1539.97% | ― | ― | 80.28% |
* Healthcare Sector Average
SNTI
Senti Biosciences
0.33
-1.06
-76.12%
KPTI
Karyopharm Therapeutics
1.79
-4.81
-72.88%
TVRD
Tvardi Therapeutics
1.91
-29.20
-93.86%
BRNS
Barinthus Biotherapeutics
0.76
-0.48
-38.79%
Senti Biosciences Corporate Events
Business Operations and StrategyM&A TransactionsRegulatory Filings and ComplianceShareholder Meetings
Senti Biosciences Advances Proxy for Merger and CVR
Neutral
Aug 20, 2026
On July 21, 2026, Senti Biosciences filed a preliminary proxy statement with the SEC related to several proposed corporate actions, including potential issuances of additional notes beyond an existing exchange cap and a possible merger of a Celado...
Private Placements and FinancingRegulatory Filings and Compliance
Senti Biosciences Details New Direct Financial Obligation
Neutral
May 26, 2026
In a brief regulatory disclosure, Senti Biosciences notes that the information described in Item 1.01 of its Current Report on Form 8-K is incorporated by reference into Item 2.03. This cross-reference indicates that details about certain financin...
Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
Disclaimer
This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.