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Cartesian Therapeutics (RNAC) Drug Pipeline

Drug pipeline
Drug NameConditionStageStatusStudy NameTrial Start DateArticle
Descartes-08Antisynthetase SyndromePhase IINot Yet RecruitingDescartes-08 in Autoantibody MyositisJan 29, 2026―
Descartes-08Childhood-Onset Systemic Lupus Erythematous, Anca-Associated Vasculitis (Aav), Juvenile Myasthenia Gravis, Juvenile Dermatomyositisphase1AndPhase2RecruitingDescartes-08 for Children, Adolescents, and Young Adults With Autoimmune DisordersJul 20, 2025
Decartes-08Myasthaenia GravisPhase IIIRecruitingInvestigating an mRNA CAR T-cell Therapy, Known as Descartes-08, as a Potential Approach to Treat Myasthenia GravisJan 23, 2025
Descartes-15Refractory Multiple Myeloma, Relapsed Multiple MyelomaPhase IActive Not RecruitingDescartes-15 for Patients With Relapsed/Refractory Multiple MyelomaFeb 28, 2024―
Descartes-08Systemic Lupus Erythematosus (Sle)Phase IIRecruitingDescartes-08 for Patients With Systemic Lupus ErythematosusSep 08, 2023
Descartes-25Relapse Multiple Myeloma, Multiple MyelomaPhase ITerminatedDescartes-25 in Relapsed/Refractory Multiple MyelomaOct 19, 2021―
Descartes 11Multiple MyelomaPhase IICompletedDescartes-11 Consolidation Treatment in Patients With High-Risk Multiple Myeloma Who Have Residual Disease After Induction TherapyJun 15, 2020―
Descartes-08Myasthenia Gravis, GeneralizedPhase IIActive Not RecruitingDescartes-08 CAR-T Cells in Generalized Myasthenia Gravis (MG)Oct 29, 2019―
Cyclophosphamide, Fludarabine, Descartes-11Multiple MyelomaPhase ITerminatedDescartes-11 in Patients With Relapsed/Refractory Multiple MyelomaJun 19, 2019―

FAQ

What are the FDA phases for drug approval?
The FDA approval process for new drugs is divided into several phases: a. Preclinical testing b. Phase 1 – Safety and dosage c. Phase 2 – Effectiveness and side effects d. Phase 3 – Confirmation of effectiveness, monitoring of adverse reactions, and comparison with existing treatments e. Phase 4 – Post-marketing studies to track long-term safety and effectiveness
What is a clinical trial?
A clinical trial is a carefully designed study in which researchers test a drug, treatment, or medical device in people to evaluate its safety, effectiveness, and potential side effects. These trials are essential for determining whether a new treatment should be approved for widespread use.
What drugs does Cartesian Therapeutics, Inc. (RNAC) have in its pipeline
Cartesian Therapeutics RNAC is currently developing the following drugs: Descartes-08, Decartes-08, Descartes-15, Descartes-25, Descartes 11, Cyclophosphamide, Fludarabine, Descartes-11. These drug candidates are in various stages of clinical development as the company works toward FDA approval.