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Repligen Corp (RGEN)
NASDAQ:RGEN
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Repligen (RGEN) AI Stock Analysis

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RGEN

Repligen

(NASDAQ:RGEN)

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Neutral 63 (OpenAI - 4o)
Rating:63Neutral
Price Target:
$162.00
▲(8.68% Upside)
Repligen's overall stock score is driven by strong earnings call performance and positive technical indicators. However, the high P/E ratio and profitability challenges weigh down the score. The company's ability to sustain growth and improve profitability will be key to enhancing its stock performance.
Positive Factors
Organic Growth
Strong organic growth across all franchises indicates robust demand and effective market strategies, supporting long-term revenue expansion.
Geographical Expansion
Significant growth in Asia Pacific and other regions highlights successful international expansion, enhancing global market presence and diversification.
Gross Margin Improvement
Improved gross margins reflect operational efficiencies and cost management, contributing to sustainable profitability and competitive positioning.
Negative Factors
Profitability Challenges
Negative profit margins indicate ongoing profitability issues, which could hinder financial stability and shareholder returns if not addressed.
Cash Flow Management
Declining free cash flow growth suggests potential inefficiencies in cash management, which could impact the company's ability to fund operations and growth.
China Market Challenges
Challenges in the China market may limit growth opportunities and affect revenue, highlighting the need for strategic adjustments in this key region.

Repligen (RGEN) vs. SPDR S&P 500 ETF (SPY)

Repligen Business Overview & Revenue Model

Company DescriptionRepligen Corporation (RGEN) is a bioprocessing company that specializes in developing and manufacturing high-purity products for the biopharmaceutical industry. The company operates primarily in the life sciences sector, focusing on enabling the production of biologic drugs through its innovative technologies and products. Repligen's core offerings include chromatography resins, filtration systems, and various tools that enhance the efficiency and effectiveness of bioprocessing workflows. Its products are utilized in the production of monoclonal antibodies, therapeutic proteins, and vaccines, catering to a growing demand in the biopharmaceutical market.
How the Company Makes MoneyRepligen generates revenue primarily through the sale of its bioprocessing products and technologies. Key revenue streams include the sale of chromatography resins, filtration products, and other consumables used in biomanufacturing processes. The company also derives income from its services related to product development and customer support. Significant partnerships with leading biopharmaceutical companies enhance its market presence and contribute to its earnings by ensuring consistent demand for its products. Additionally, Repligen's focus on innovation and expansion into new markets helps to drive growth and diversify its revenue base.

Repligen Earnings Call Summary

Earnings Call Date:Oct 28, 2025
(Q2-2025)
|
% Change Since: |
Next Earnings Date:Feb 25, 2026
Earnings Call Sentiment Positive
The earnings call reflects a strong performance with significant organic growth, record order growth, and improved financial guidance. However, challenges remain, particularly with the China market and gene therapy headwinds. Despite these challenges, the company is optimistic about its strategic investments and future growth opportunities.
Q2-2025 Updates
Positive Updates
Strong Organic Non-COVID Growth
Repligen achieved 17% organic non-COVID growth in Q2 2025, marking the highest growth rate since 2022. This includes 20% revenue growth in biopharma and strong performance across all regions.
Record Order Growth
Orders grew over 20% year-over-year and high teens organically, marking the eighth consecutive quarter of orders exceeding non-COVID revenue.
Capital Equipment Performance
Capital equipment revenue returned to growth in the high teens, with orders growing greater than 20%, driven by traction in ATS and downstream systems.
Chromatography Segment Success
Chromatography had a record quarter with greater than 40% revenue growth, driven by large-scale column demand from pharma and Europe.
Positive Financial Guidance
Repligen increased its revenue guidance to $715 million to $735 million, reflecting 12.5% to 15.5% organic non-COVID growth.
Negative Updates
China Market Challenges
While China orders picked up significantly, the company remains cautious due to potential tariff-related dynamics affecting future performance.
Gene Therapy Revenue Headwind
The gene therapy platform represented $10 million of revenue in the first half of 2025 with minimal incremental revenue expected for the remainder of the year, posing a 1% headwind to guidance.
Muted New Modality Demand
New modalities revenue grew mid-teens, but orders were flat, leading to expectations of muted demand in the second half of 2025.
Gross Margin Pressure
Gross margin was flat year-over-year at 51.1%, with mix and tariffs slightly impacting margins.
Company Guidance
During Repligen Corporation's second quarter 2025 earnings call, the company provided detailed financial guidance for the full year. Repligen reported a 17% organic non-COVID revenue growth, with key performance driven by Chromatography, which saw over 40% revenue growth, and Filtration, which posted mid-teens non-COVID growth. The company experienced a strong demand for consumables, with capital equipment growing in the high teens. Geographically, all regions saw mid-teens growth, with China orders notably rebounding. Repligen raised its organic growth guidance, expecting full-year revenue between $715 million to $735 million, reflecting 12.5% to 15.5% organic non-COVID growth. The company aims for gross margins of 52% to 53% and an adjusted operating margin between 13.5% and 14.5%. The strategy includes doubling the company's size in the medium term, focusing on organic growth with modest M&A assumptions, maintaining profitability, and expanding gross margins and operating leverage.

Repligen Financial Statement Overview

Summary
Repligen shows a mixed financial performance with strong balance sheet and operational cash flow, but faces challenges in profitability and growth. The company maintains a strong equity position and low leverage, yet needs to address its declining net income and EBIT margins to improve its financial health and investor confidence.
Income Statement
55
Neutral
Repligen's revenue shows a marginal growth from the previous year, but has declined from 2022. The gross profit margin for TTM is approximately 54.88%, indicating decent cost management. However, the company is experiencing negative net income and EBIT margins, highlighting profitability challenges. The EBITDA margin is positive at 13.80%, suggesting some operational efficiency.
Balance Sheet
60
Neutral
The company's balance sheet is relatively strong with a debt-to-equity ratio of approximately 0.34, indicating low leverage. The equity ratio is around 69.60%, reflecting a healthy balance of equity financing. However, the return on equity is negative due to net losses, which is a concern for investors seeking returns.
Cash Flow
50
Neutral
Repligen's cash flow statement shows a decrease in free cash flow compared to the annual report, with a negative free cash flow growth rate. The operating cash flow to net income ratio is negative due to the net loss, but operating cash flow remains positive, which indicates underlying operational strength despite profitability concerns.
BreakdownTTMDec 2024Dec 2023Dec 2022Dec 2021Dec 2020
Income Statement
Total Revenue673.96M634.44M632.36M801.54M670.53M366.26M
Gross Profit326.42M274.64M308.83M455.71M391.25M209.63M
EBITDA135.55M82.10M127.77M246.93M211.56M101.62M
Net Income-13.83M-25.51M35.60M185.96M128.29M59.93M
Balance Sheet
Total Assets2.90B2.83B2.83B2.53B2.36B1.90B
Cash, Cash Equivalents and Short-Term Investments708.86M757.36M751.32M623.76M603.81M717.29M
Total Debt686.06M686.25M711.80M422.96M366.05M275.42M
Total Liabilities839.89M856.95M866.34M620.90M608.29M373.74M
Stockholders Equity2.06B1.97B1.96B1.91B1.75B1.53B
Cash Flow
Free Cash Flow103.81M142.49M74.93M38.74M47.74M36.28M
Operating Cash Flow132.11M175.39M113.92M172.08M119.02M62.63M
Investing Cash Flow-152.57M-86.38M-123.28M-233.24M-221.17M-201.38M
Financing Cash Flow-83.32M-82.90M248.96M-13.34M961.00K305.92M

Repligen Technical Analysis

Technical Analysis Sentiment
Positive
Last Price149.06
Price Trends
50DMA
135.46
Positive
100DMA
128.77
Positive
200DMA
135.03
Positive
Market Momentum
MACD
4.59
Positive
RSI
51.94
Neutral
STOCH
7.32
Positive
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For RGEN, the sentiment is Positive. The current price of 149.06 is below the 20-day moving average (MA) of 152.48, above the 50-day MA of 135.46, and above the 200-day MA of 135.03, indicating a neutral trend. The MACD of 4.59 indicates Positive momentum. The RSI at 51.94 is Neutral, neither overbought nor oversold. The STOCH value of 7.32 is Positive, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Positive sentiment for RGEN.

Repligen Risk Analysis

Repligen disclosed 41 risk factors in its most recent earnings report. Repligen reported the most risks in the "Finance & Corporate" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

Repligen Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
$5.19B44.808.30%11.49%-2.89%
$5.50B29.304.36%1.09%1.11%-23.73%
$8.39B6,775.450.08%11.74%
$6.88B47.109.55%0.24%5.95%7.73%
$5.29B-4.69%6.23%17.53%
$7.86B-0.30-43.30%2.27%22.53%-2.21%
$7.64B18.5915.79%1.58%2.50%25.05%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
RGEN
Repligen
149.06
3.11
2.13%
ATR
AptarGroup
116.01
-52.21
-31.04%
MMSI
Merit Medical Systems
87.54
-11.25
-11.39%
TFX
Teleflex
124.47
-77.06
-38.24%
STVN
Stevanato Group
25.22
2.78
12.39%
BLCO
Bausch + Lomb Corporation
15.25
-4.56
-23.02%

Repligen Corporate Events

Repligen Corporation Reports Strong Q3 2025 Results
Oct 29, 2025

Repligen Corporation is a global life sciences company that specializes in developing and commercializing innovative bioprocessing technologies and systems, primarily serving biopharmaceutical drug developers and contract development and manufacturing organizations (CDMOs). The company is headquartered in Waltham, Massachusetts, with manufacturing sites in the U.S. and Europe.

Business Operations and StrategyExecutive/Board ChangesRegulatory Filings and Compliance
Repligen Appoints Violetta Hughes as Chief Accounting Officer
Positive
Sep 2, 2025

On September 2, 2025, Repligen Corporation announced the appointment of Violetta Hughes as the new Chief Accounting Officer, effective September 1, 2025. This strategic move aims to enhance the company’s financial reporting infrastructure and compliance with the Sarbanes–Oxley Act. Ms. Hughes, a seasoned finance executive with over 25 years of experience, will replace Jason K. Garland, who will continue as the Chief Financial Officer focusing on corporate strategy and growth. Her extensive background in financial governance and SOX compliance is expected to bring significant improvements to Repligen’s financial transparency and strategic decision-making processes.

The most recent analyst rating on (RGEN) stock is a Buy with a $207.00 price target. To see the full list of analyst forecasts on Repligen stock, see the RGEN Stock Forecast page.

Repligen’s Earnings Call Highlights Robust Growth
Jul 31, 2025

Repligen’s recent earnings call showcased a robust performance, highlighting significant growth in non-COVID areas, particularly in biopharma and chromatography sectors. Despite facing challenges from the gene therapy platform and muted biotech orders, the company’s overall financial health and strategic initiatives, coupled with increased guidance, suggest a positive outlook for the future.

Repligen Corporation Reports Strong Q2 2025 Growth
Jul 30, 2025

Repligen Corporation is a global life sciences company specializing in bioprocessing technologies, serving biopharmaceutical drug developers and contract development and manufacturing organizations worldwide. In its second quarter of 2025, Repligen reported a revenue of $182 million, marking a 15% year-over-year increase, with a notable 17% organic growth excluding COVID-related revenue. Orders grew by over 20% year-over-year, reflecting strong demand across its portfolio. The company has raised its revenue guidance for the full year to a range of $715 to $735 million, indicating a 12.5% to 15.5% year-over-year non-COVID organic growth. Key highlights from the quarter include broad-based revenue strength across all franchises, with consumables and capital equipment showing significant growth. Repligen also launched a new product, the ProConnex® MixOne, and published its 2024 Sustainability report. Financially, the company achieved a GAAP net income of $15 million, up from $6 million the previous year, and an adjusted net income of $21 million. Looking ahead, Repligen remains optimistic about its growth prospects, despite facing headwinds from new modalities, and continues to focus on executing its strategic initiatives to drive further success.

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Oct 29, 2025