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Lexeo Therapeutics, Inc. (LXEO)
NASDAQ:LXEO
US Market
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Lexeo Therapeutics, Inc. (LXEO) AI Stock Analysis

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LXEO

Lexeo Therapeutics, Inc.

(NASDAQ:LXEO)

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Neutral 52 (OpenAI - 5.2)
Rating:52Neutral
Price Target:
$5.00
▼(-2.53% Downside)
Action:Reiterated
Date:08/17/26
The score is held back primarily by weak financial performance (no meaningful revenue, large losses, and significant cash burn). Offsetting this are moderately supportive technical signals and positive clinical/regulatory progress (including RMAT designation and pivotal-trial advancement), but valuation remains constrained by ongoing losses and no indicated dividend yield.
Positive Factors
Pivotal Trial Progress
Advancing LX2006 into a pivotal study moves the lead program toward potential regulatory submission and commercial development, creating a durable clinical milestone if enrollment and efficacy remain on track.
Negative Factors
No Meaningful Revenue
Lexeo remains pre-commercial, with no sustained product revenue to offset research and development costs. This leaves fundamental performance dependent on clinical progress and future financing or partnering rather than operating sales.
Read all positive and negative factors
Positive Factors
Negative Factors
Pivotal Trial Progress
Advancing LX2006 into a pivotal study moves the lead program toward potential regulatory submission and commercial development, creating a durable clinical milestone if enrollment and efficacy remain on track.
Read all positive factors

Lexeo Therapeutics, Inc. (LXEO) vs. SPDR S&P 500 ETF (SPY)

Lexeo Therapeutics, Inc. Business Overview & Revenue Model

Company Description
Lexeo Therapeutics, Inc. is a genetic medicine firm currently in the clinical development phase, dedicated to addressing both inherited and acquired medical conditions. Its robust pipeline features several gene therapy candidates. These include LX...
How the Company Makes Money
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Lexeo Therapeutics, Inc. Financial Statement Overview

Summary
Financial performance is weak overall: revenue is effectively zero while losses remain large (TTM net loss about $87M) and cash burn is substantial (TTM operating cash flow about -$88M; free cash flow about -$89M). The main offset is a relatively solid, low-leverage balance sheet (low debt and sizable equity), but ongoing deficits imply continued reliance on external financing.
Income Statement
18
Very Negative
Balance Sheet
62
Positive
Cash Flow
24
Negative
BreakdownTTMDec 2025Dec 2024Dec 2023Dec 2022Dec 2021
Income Statement
Total Revenue0.000.000.000.00654.00K1.66M
Gross Profit-546.00K0.000.000.00654.00K1.66M
EBITDA-85.44M-97.68M-96.19M-64.35M-58.04M-50.61M
Net Income-87.27M-99.96M-98.33M-66.39M-59.28M-50.62M
Balance Sheet
Total Assets254.90M268.69M146.94M139.81M97.08M136.86M
Cash, Cash Equivalents and Short-Term Investments211.70M181.77M121.52M121.47M77.33M135.86M
Total Debt6.81M7.89M9.92M11.64M13.48M0.00
Total Liabilities19.84M22.02M30.10M26.27M210.03M192.46M
Stockholders Equity235.06M246.67M116.84M113.53M-112.95M-55.60M
Cash Flow
Free Cash Flow-88.70M-98.96M-81.63M-59.66M-55.46M-44.37M
Operating Cash Flow-88.37M-98.56M-81.15M-59.50M-54.56M-44.18M
Investing Cash Flow-24.95M-90.25M-94.08M-165.00K-901.00K-188.00K
Financing Cash Flow170.68M216.79M88.78M103.79M189.00K150.86M

Lexeo Therapeutics, Inc. Technical Analysis

Technical Analysis Sentiment
Positive
Last Price5.13
Price Trends
50DMA
4.74
Positive
100DMA
5.13
Negative
200DMA
6.54
Negative
Market Momentum
MACD
0.11
Negative
RSI
54.46
Neutral
STOCH
45.39
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For LXEO, the sentiment is Positive. The current price of 5.13 is above the 20-day moving average (MA) of 4.76, above the 50-day MA of 4.74, and below the 200-day MA of 6.54, indicating a neutral trend. The MACD of 0.11 indicates Negative momentum. The RSI at 54.46 is Neutral, neither overbought nor oversold. The STOCH value of 45.39 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Positive sentiment for LXEO.

Lexeo Therapeutics, Inc. Risk Analysis

Lexeo Therapeutics, Inc. disclosed 75 risk factors in its most recent earnings report. Lexeo Therapeutics, Inc. reported the most risks in the "Tech & Innovation" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

Lexeo Therapeutics, Inc. Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
55
Neutral
$432.15M-2.10-137.39%-27.00%
52
Neutral
$420.90M-4.36-41.85%64.51%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
50
Neutral
$363.46M-9.31-77.68%-3.42%
44
Neutral
$24.28M-0.64-64.17%-100.00%82.57%
44
Neutral
$447.29M-11.60-34.82%41.21%
41
Neutral
$481.97M-3.82-56.60%-100.00%-49.28%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
LXEO
Lexeo Therapeutics, Inc.
4.99
0.23
4.83%
TVRD
Tvardi Therapeutics
1.80
-28.47
-94.05%
LRMR
Larimar Therapeutics
4.05
0.14
3.58%
CAPR
Capricor Therapeutics
10.06
3.80
60.70%
BNTC
Benitec Biopharma
12.67
-0.36
-2.76%
DMAC
Diamedica Therapeutics
6.75
0.88
14.99%

Lexeo Therapeutics, Inc. Corporate Events

Business Operations and StrategyFinancial Disclosures
Lexeo Therapeutics advances gene therapy and gains RMAT status
Positive
Aug 12, 2026
On August 12, 2026, Lexeo Therapeutics reported second-quarter 2026 results and detailed progress across its gene therapy portfolio, underscoring a push toward pivotal development in inherited heart diseases. In June, the company finalized the SUN...
Executive/Board ChangesShareholder Meetings
Lexeo Shareholders Reelect Directors, Ratify KPMG Auditor
Positive
Jun 29, 2026
Lexeo Therapeutics, Inc. held its 2026 Annual Meeting of Stockholders virtually on June 25, 2026, where shareholders voted on key corporate governance matters, signaling continued engagement with the company’s strategic direction. Stockholde...
Business Operations and StrategyProduct-Related Announcements
Lexeo Advances Pivotal LX2006 Trial for FA Cardiomyopathy
Positive
Jun 15, 2026
On June 15, 2026, Lexeo Therapeutics announced it has finalized the pivotal SUNRISE-FA 2 trial protocol and statistical analysis plan for LX2006, its gene therapy candidate for Friedreich ataxia cardiomyopathy, aiming to support a future Biologics...
Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Aug 17, 2026