Chiome Bioscience Inc. AI Stock Analysis
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Chiome Bioscience Inc. (4583) AI Stock Analysis
Chiome Bioscience Inc.
(TSE/TYO:4583)
The score is held down primarily by persistent large losses and sustained negative operating/free cash flow, despite low leverage. Technicals provide some offset with improving near-to-mid-term momentum (above 20/50/100-day averages and positive MACD), while valuation remains difficult to support due to a negative P/E and no dividend yield data.
Chiome Bioscience Inc. (4583) vs. iShares MSCI Japan ETF (EWJ)
- Market Cap
- JPY 6.33B
- Dividend Yield
- ―
- Average Volume (3M)
- 1.62M
- Price to Earnings (P/E)
- -6.2
- Beta (1Y)
- 0.73
- Revenue Growth
- -13.40%
- EPS Growth
- 7.50%
- Country
- Japan
- Employees
- 49
- Sector
- General
- Sector Strength
- 55
- Industry
- Biotechnology
Chiome Bioscience Inc. Business Overview & Revenue Model
Company Description
Chiome Bioscience Inc. engages in the research and development of drug discovery technology platforms worldwide. It operates in two segments, Drug Discovery Business and Drug Discovery Support Business. The company offers ADLib System, a technology f...
How the Company Makes Money
Publicly available, company-specific details on Chiome Bioscience Inc.’s current revenue model and the breakdown of its revenue streams (e.g., product sales vs. licensing, collaboration milestones, research funding, or royalties), as well as signific...
Chiome Bioscience Inc. Financial Statement Overview
Summary
Financial performance is weak: revenue has been volatile and declined materially in 2025 (~23% drop), while profitability remains deeply negative (net margins roughly -131% to -269%). Cash flow is consistently negative with ongoing cash burn, raising funding risk. The balance sheet is a relative positive with modest leverage, but persistent losses threaten equity over time.
Income Statement
18Very NegativeBalance Sheet
54NeutralCash Flow
16Very Negative| Breakdown | TTM | Dec 2024 | Dec 2023 | Dec 2022 | Dec 2021 | Dec 2020 |
|---|---|---|---|---|---|---|
Income Statement | ||||||
| Total Revenue | 615.15M | 593.29M | 780.81M | 682.46M | 630.82M | 480.85M |
| Gross Profit | 375.24M | 355.58M | 432.02M | 397.72M | 347.78M | 242.81M |
| EBITDA | -910.50M | -972.64M | -1.01B | -1.21B | -1.24B | -1.28B |
| Net Income | -925.73M | -982.78M | -1.02B | -1.22B | -1.24B | -1.29B |
Balance Sheet | ||||||
| Total Assets | 1.91B | 1.73B | 2.47B | 1.75B | 2.22B | 3.49B |
| Cash, Cash Equivalents and Short-Term Investments | 1.37B | 1.21B | 2.06B | 1.33B | 1.73B | 2.69B |
| Total Debt | 67.50M | 261.70M | 281.50M | 291.00M | 184.00M | 180.00M |
| Total Liabilities | 341.26M | 605.44M | 548.55M | 593.73M | 424.72M | 384.58M |
| Stockholders Equity | 1.57B | 1.12B | 1.92B | 1.16B | 1.79B | 3.11B |
Cash Flow | ||||||
| Free Cash Flow | 0 | -976.07M | -1.00B | 0 | -1.19B | 0 |
| Operating Cash Flow | 0 | -935.99M | -1.00B | -1.07B | -1.19B | -1.36B |
| Investing Cash Flow | 0 | -55.46M | 0 | 173.00K | 0 | -3.52M |
| Financing Cash Flow | 0 | 133.20M | 1.74B | 667.30M | 1.13B | 1.94B |
Chiome Bioscience Inc. Technical Analysis
Price Trends
Market Momentum
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For JP:4583, the sentiment is Negative. The current price of 77.00 is below the 20-day moving average (MA) of 87.40, below the 50-day MA of 92.08, and below the 200-day MA of 92.22, indicating a bearish trend. The MACD of -3.94 indicates Positive momentum. The RSI at 36.30 is Neutral, neither overbought nor oversold. The STOCH value of 30.16 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Negative sentiment for JP:4583.
Chiome Bioscience Inc. Peers Comparison
Overall Rating
JP:457081Outperform
JP:456563Neutral
JP:457958Neutral
JP:458855Neutral
JP:458752Neutral- JP:458349Neutral
Financial Indicators
| Name | Overall Rating | Market Cap | P/E Ratio | ROE | Dividend Yield | Revenue Growth | EPS Growth |
|---|---|---|---|---|---|---|---|
| JP:4570 | 81Outperform | JPY 9.16B | 23.72 | ― | 0.62% | 7.10% | 17.17% |
| JP:4565 | 63Neutral | JPY 166.34B | -30.09 | -8.51% | ― | 23.72% | 12.48% |
| JP:4579 | 58Neutral | JPY 17.31B | 75.86 | ― | ― | 20.64% | ― |
| Sector * | 55Neutral | $6.65B | 3.83 | -15.92% | 6.20% | 10.91% | 7.18% |
| JP:4588 | 55Neutral | JPY 221.84B | -145.74 | ― | ― | 1748.97% | 35.11% |
| JP:4587 | 52Neutral | JPY 143.72B | -36.36 | -7.17% | ― | 14.25% | 50.07% |
| JP:4583 | 49Neutral | JPY 6.71B | -6.19 | ― | ― | -13.40% | 7.50% |
* General Sector Average
Performance Comparison
| Show on chart | Ticker | Company Name | Price | Change | % Change |
|---|---|---|---|---|---|
| JP:4583 | Chiome Bioscience Inc. | 77.00 | -49.00 | -38.89% | |
| JP:4587 | Peptidream | 1075.00 | -555.00 | -34.05% | |
| JP:4565 | Sosei Group Corporation | 1811.00 | 962.00 | 113.31% | |
| JP:4570 | Immuno-Biological Laboratories Co., Ltd. | 974.00 | 375.57 | 62.76% | |
| JP:4579 | RaQualia Pharma Inc. | 679.00 | 154.00 | 29.33% | |
| JP:4588 | Oncolys BioPharma, Inc. | 7900.00 | 6842.00 | 646.69% |
Chiome Bioscience Inc. Corporate Events
Chiome Bioscience Provides Supplementary Information on Q3 FY12/26 Financial Results
Chiome Bioscience Inc. is presented as focused on accelerating monoclonal antibody (mAb) drug discovery and development for therapeutics addressing current medical unmet needs.The Nov. 10, 2026 supplementary information is organized around Q3 FY12/26...
Chiome Reports Nine-Month Sales of ¥406 Million, Narrower Losses
Chiome Bioscience Inc. is a bioscience company engaged in Drug Discovery and Development and Drug Discovery Support businesses. Its shares are listed on the Tokyo Stock Exchange under code 4583, and the release reports non-consolidated results under...
Chiome Bioscience Outlines Q2 FY2026 Results and R&D Focus
Chiome Bioscience has released supplementary information for its second-quarter fiscal 2026 results, outlining financial performance and operational highlights for the period. The materials also reference updates to the company’s therapeutic antibody...
Chiome Bioscience Narrows Losses as Sales Rise and Balance Sheet Strengthens
Chiome Bioscience reported non-consolidated net sales of ¥273 million for the six months ended June 30, 2026, an 8.7% increase year on year, while narrowing its net loss to ¥483 million as operating and ordinary losses also improved. Total assets ros...
Disclaimer
This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.
Date of analysis: Sep 10, 2026