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Chiome Bioscience Inc. (JP:4583)
:4583
Japanese Market
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Chiome Bioscience Inc. (4583) AI Stock Analysis

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JP:4583

Chiome Bioscience Inc.

(4583)

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Neutral 52 (OpenAI - Gpt-5.6Sol)
Rating:52Neutral
Price Target:
¥100.00
▼(-5.66% Downside)
Action:Reiterated
Date:09/08/26
The score is primarily weighed down by persistent large losses and sustained cash burn despite low leverage on the balance sheet. Technicals are a key offset, with price trading above major moving averages and positive momentum indicators. Valuation remains challenged due to negative earnings (negative P/E) and no stated dividend yield.
Positive Factors
Low financial leverage
Modest leverage gives Chiome greater financial flexibility than a highly indebted biotechnology company. Lower debt obligations can reduce interest and refinancing pressure, preserve funding choices, and provide a stronger buffer while the company develops therapeutic candidates.
Negative Factors
Declining and volatile revenue
Revenue volatility and the sharp 2025 decline weaken visibility into the company’s ability to scale its biotechnology activities. Without a sustained top-line recovery, fixed research and development spending is harder to absorb and progress toward profitability remains uncertain.
Read all positive and negative factors
Positive Factors
Negative Factors
Low financial leverage
Modest leverage gives Chiome greater financial flexibility than a highly indebted biotechnology company. Lower debt obligations can reduce interest and refinancing pressure, preserve funding choices, and provide a stronger buffer while the company develops therapeutic candidates.
Read all positive factors

Chiome Bioscience Inc. (4583) vs. iShares MSCI Japan ETF (EWJ)

Chiome Bioscience Inc. Business Overview & Revenue Model

Company Description
Chiome Bioscience Inc. engages in the research and development of drug discovery technology platforms worldwide. It operates in two segments, Drug Discovery Business and Drug Discovery Support Business. The company offers ADLib System, a technolog...
How the Company Makes Money
Publicly available, company-specific details on Chiome Bioscience Inc.’s current revenue model and the breakdown of its revenue streams (e.g., product sales vs. licensing, collaboration milestones, research funding, or royalties), as well as signi...

Chiome Bioscience Inc. Financial Statement Overview

Summary
Income statement and cash flow quality are weak: revenue is volatile and fell ~23% in 2025, profitability remains deeply negative (net margins roughly -131% to -269%), and operating/free cash flow are consistently negative (about -0.94B to -1.36B), indicating ongoing cash burn. Balance sheet leverage is modest (low debt-to-equity), but equity volatility and persistent losses raise risk of continued erosion.
Income Statement
18
Very Negative
Balance Sheet
54
Neutral
Cash Flow
16
Very Negative
BreakdownTTMDec 2024Dec 2023Dec 2022Dec 2021Dec 2020
Income Statement
Total Revenue615.15M593.29M780.81M682.46M630.82M712.93M
Gross Profit375.24M355.58M432.02M397.72M347.78M420.59M
EBITDA-910.50M-972.64M-1.01B-1.21B-1.24B-1.46B
Net Income-925.73M-982.78M-1.02B-1.22B-1.24B-1.48B
Balance Sheet
Total Assets1.91B1.73B2.47B1.75B2.22B2.34B
Cash, Cash Equivalents and Short-Term Investments1.37B1.21B2.06B1.33B1.73B1.79B
Total Debt67.50M261.70M281.50M291.00M184.00M183.00M
Total Liabilities341.26M605.44M548.55M593.73M424.72M446.39M
Stockholders Equity1.57B1.12B1.92B1.16B1.79B1.89B
Cash Flow
Free Cash Flow0.00-976.07M-1.00B0.00-1.19B0.00
Operating Cash Flow0.00-935.99M-1.00B-1.07B-1.19B-1.13B
Investing Cash Flow0.00-55.46M0.00173.00K0.00-35.38M
Financing Cash Flow0.00133.20M1.74B667.30M1.13B271.35M

Chiome Bioscience Inc. Technical Analysis

Technical Analysis Sentiment
Positive
Last Price106.00
Price Trends
50DMA
77.06
Positive
100DMA
81.66
Positive
200DMA
96.75
Positive
Market Momentum
MACD
5.36
Negative
RSI
65.61
Neutral
STOCH
59.10
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For JP:4583, the sentiment is Positive. The current price of 106 is above the 20-day moving average (MA) of 84.15, above the 50-day MA of 77.06, and above the 200-day MA of 96.75, indicating a bullish trend. The MACD of 5.36 indicates Negative momentum. The RSI at 65.61 is Neutral, neither overbought nor oversold. The STOCH value of 59.10 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Positive sentiment for JP:4583.

Chiome Bioscience Inc. Peers Comparison

Overall Rating
UnderperformOutperform
Sector (55)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
70
Outperform
¥9.89B26.860.65%13.46%42.41%
58
Neutral
¥14.29B61.3420.64%
55
Neutral
$6.65B3.83-15.92%6.20%10.91%7.18%
52
Neutral
¥9.17B-8.54-19.99%16.36%
50
Neutral
¥105.58B-13.20-12.23%0.33%7.12%-137.21%
50
Neutral
¥135.23B-83.611662.38%42.86%
48
Neutral
¥138.78B-38.03-7.17%0.62%27.66%
* General Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
JP:4583
Chiome Bioscience Inc.
99.00
-41.00
-29.29%
JP:4587
Peptidream
1,088.50
-626.50
-36.53%
JP:4565
Sosei Group
1,168.00
133.00
12.85%
JP:4570
Immuno-Biological Laboratories Co., Ltd.
1,151.00
680.02
144.38%
JP:4579
RaQualia Pharma Inc.
552.00
-34.00
-5.80%
JP:4588
Oncolys BioPharma, Inc.
4,950.00
4,294.00
654.57%

Chiome Bioscience Inc. Corporate Events

Chiome Bioscience Outlines Q2 FY2026 Results and R&D Focus
Aug 13, 2026
Chiome Bioscience has released supplementary information for its second-quarter fiscal 2026 results, outlining financial performance and operational highlights for the period. The materials also reference updates to the company’s therapeutic...
Chiome Bioscience Narrows Losses as Sales Rise and Balance Sheet Strengthens
Aug 13, 2026
Chiome Bioscience reported non-consolidated net sales of ¥273 million for the six months ended June 30, 2026, an 8.7% increase year on year, while narrowing its net loss to ¥483 million as operating and ordinary losses also improved. Tot...
Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Sep 08, 2026