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Chiome Bioscience Inc. (JP:4583)
:4583
Japanese Market
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Chiome Bioscience Inc. (4583) AI Stock Analysis

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JP:4583

Chiome Bioscience Inc.

(4583)

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Underperform 40 (OpenAI - Gpt-5.6Sol)
Rating:40Underperform
Price Target:
¥79.00
▼(-25.47% Downside)
Action:Downgraded
Date:06/03/26
The score is driven primarily by weak financial performance (persistent losses and ongoing cash burn) and bearish technicals (price below major moving averages with negative momentum). Valuation provides only limited support because the company is loss-making and no dividend yield is available.
Positive Factors
Modest Leverage
Low leverage limits interest and refinancing pressure, preserving financial flexibility while the company funds drug discovery. This provides a stronger balance-sheet base than a highly indebted biotechnology peer, although it does not offset ongoing operating losses.
Negative Factors
Persistent Deep Losses
Large recurring losses indicate that the business has not yet achieved economic scale or a sustainable earnings model. Continued deficits can erode equity, constrain investment in oncology pipelines, and increase reliance on future financing or strategic support.
Read all positive and negative factors
Positive Factors
Negative Factors
Modest Leverage
Low leverage limits interest and refinancing pressure, preserving financial flexibility while the company funds drug discovery. This provides a stronger balance-sheet base than a highly indebted biotechnology peer, although it does not offset ongoing operating losses.
Read all positive factors

Chiome Bioscience Inc. (4583) vs. iShares MSCI Japan ETF (EWJ)

Chiome Bioscience Inc. Business Overview & Revenue Model

Company Description
Chiome Bioscience Inc. engages in the research and development of drug discovery technology platforms worldwide. It operates in two segments, Drug Discovery Business and Drug Discovery Support Business. The company offers ADLib System, a technolog...
How the Company Makes Money
Publicly available, company-specific details on Chiome Bioscience Inc.’s current revenue model and the breakdown of its revenue streams (e.g., product sales vs. licensing, collaboration milestones, research funding, or royalties), as well as signi...

Chiome Bioscience Inc. Financial Statement Overview

Summary
Financial profile is weak: income statement and cash flow scores are very low due to persistent large losses, negative margins, and ongoing cash burn. Balance sheet leverage is modest, but equity volatility and negative returns reflect continued strain.
Income Statement
18
Very Negative
Balance Sheet
54
Neutral
Cash Flow
16
Very Negative
BreakdownTTMDec 2024Dec 2023Dec 2022Dec 2021Dec 2020
Income Statement
Total Revenue601.75M593.29M780.81M682.46M630.82M712.93M
Gross Profit355.46M355.58M432.02M397.72M347.78M420.59M
EBITDA-938.02M-972.64M-1.01B-1.21B-1.24B-1.46B
Net Income-949.86M-982.78M-1.02B-1.22B-1.24B-1.48B
Balance Sheet
Total Assets1.67B1.73B2.47B1.75B2.22B2.34B
Cash, Cash Equivalents and Short-Term Investments1.14B1.21B2.06B1.33B1.73B1.79B
Total Debt86.70M261.70M281.50M291.00M184.00M183.00M
Total Liabilities358.22M605.44M548.55M593.73M424.72M446.39M
Stockholders Equity1.31B1.12B1.92B1.16B1.79B1.89B
Cash Flow
Free Cash Flow0.00-976.07M-1.00B0.00-1.19B0.00
Operating Cash Flow0.00-935.99M-1.00B-1.07B-1.19B-1.13B
Investing Cash Flow0.00-55.46M0.00173.00K0.00-35.38M
Financing Cash Flow0.00133.20M1.74B667.30M1.13B271.35M

Chiome Bioscience Inc. Technical Analysis

Technical Analysis Sentiment
Positive
Last Price106.00
Price Trends
50DMA
73.68
Positive
100DMA
82.86
Positive
200DMA
98.43
Negative
Market Momentum
MACD
3.42
Negative
RSI
71.99
Negative
STOCH
75.75
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For JP:4583, the sentiment is Positive. The current price of 106 is above the 20-day moving average (MA) of 76.20, above the 50-day MA of 73.68, and above the 200-day MA of 98.43, indicating a neutral trend. The MACD of 3.42 indicates Negative momentum. The RSI at 71.99 is Negative, neither overbought nor oversold. The STOCH value of 75.75 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Positive sentiment for JP:4583.

Chiome Bioscience Inc. Peers Comparison

Overall Rating
UnderperformOutperform
Sector (55)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
71
Outperform
¥9.91B26.5813.46%42.41%
58
Neutral
¥14.68B64.2520.64%
55
Neutral
$6.65B3.83-15.92%6.20%10.91%7.18%
51
Neutral
¥118.45B-73.141662.38%42.86%
50
Neutral
¥102.62B-12.92-15.58%7.12%-137.21%
48
Neutral
¥144.63B-39.43-6.88%0.62%27.66%
40
Underperform
¥6.88B-6.48-19.99%16.36%
* General Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
JP:4583
Chiome Bioscience Inc.
85.00
-51.00
-37.50%
JP:4587
Peptidream
1,108.50
-415.00
-27.24%
JP:4565
Sosei Group
1,116.00
212.00
23.45%
JP:4570
Immuno-Biological Laboratories Co., Ltd.
1,051.00
574.05
120.36%
JP:4579
RaQualia Pharma Inc.
575.00
26.00
4.74%
JP:4588
Oncolys BioPharma, Inc.
4,020.00
3,382.00
530.09%

Chiome Bioscience Inc. Corporate Events

Chiome Bioscience Outlines Q2 FY2026 Results and R&D Focus
Aug 13, 2026
Chiome Bioscience has released supplementary information for its second-quarter fiscal 2026 results, outlining financial performance and operational highlights for the period. The materials also reference updates to the company’s therapeutic...
Chiome Bioscience Narrows Losses as Sales Rise and Balance Sheet Strengthens
Aug 13, 2026
Chiome Bioscience reported non-consolidated net sales of ¥273 million for the six months ended June 30, 2026, an 8.7% increase year on year, while narrowing its net loss to ¥483 million as operating and ordinary losses also improved. Tot...
Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Jun 03, 2026