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Sino Biopharmaceutical Ltd (HK:1177)
:1177
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Sino Biopharmaceutical (1177) AI Stock Analysis

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HK:1177

Sino Biopharmaceutical

(1177)

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Neutral 54 (OpenAI - 4o)
Rating:54Neutral
Price Target:
HK$7.00
▲(0.14% Upside)
The overall stock score is primarily influenced by strong financial performance, despite concerns over cash flow transparency. Technical analysis indicates bearish momentum, and the valuation suggests the stock is expensive. The lack of earnings call data and corporate events means these factors do not impact the score.

Sino Biopharmaceutical (1177) vs. iShares MSCI Hong Kong ETF (EWH)

Sino Biopharmaceutical Business Overview & Revenue Model

Company DescriptionSino Biopharmaceutical Limited, listed on the Hong Kong Stock Exchange under the ticker 1177, is a leading pharmaceutical conglomerate in China. The company is involved in the research, development, manufacture, and sale of a broad range of pharmaceutical products. Its core sectors include oncology, cardiovascular, hepatitis, and respiratory drugs, along with a focus on innovative and generic medicines. With a strong emphasis on R&D, Sino Biopharmaceutical aims to deliver high-quality and affordable healthcare solutions.
How the Company Makes MoneySino Biopharmaceutical generates revenue primarily through the sale of its pharmaceutical products across various therapeutic areas. The company's revenue streams include sales from both innovative drugs and generic medicines, particularly in areas such as oncology, cardiovascular, and respiratory diseases. A significant portion of its earnings is driven by its robust distribution network and strategic partnerships within the healthcare industry. The company also invests heavily in research and development to create new drugs and improve existing ones, which helps to maintain a competitive edge and drive long-term growth. Collaborations with international pharmaceutical companies and research institutions further enhance its product offerings and market reach.

Sino Biopharmaceutical Financial Statement Overview

Summary
Sino Biopharmaceutical shows strong profitability with high gross and net profit margins. The balance sheet is stable with a reasonable debt-to-equity ratio, but cash flow transparency is a concern due to missing operating cash flow data.
Income Statement
75
Positive
Sino Biopharmaceutical demonstrated strong gross profit margins and net profit growth over the past year. The gross profit margin stands at a high level, reflecting efficient cost management. The net profit margin also improved, showcasing enhanced profitability. However, revenue growth was moderate, indicating room for improvement in expanding sales.
Balance Sheet
70
Positive
The company maintains a healthy balance sheet with a reasonable debt-to-equity ratio, indicating prudent leverage. Return on Equity (ROE) shows positive returns, although room for optimization exists. The equity ratio remains solid, reflecting a stable capital structure, though the increasing debt might warrant caution.
Cash Flow
60
Neutral
Cash flow metrics present a mixed picture. While the company has generated positive free cash flow historically, there was an absence of operating cash flow data for the latest year, which raises concerns about cash generation capabilities. The free cash flow to net income ratio suggests efficient cash conversion, yet the lack of current data creates uncertainty.
BreakdownTTMDec 2024Dec 2023Dec 2022Dec 2021Dec 2020
Income Statement
Total Revenue30.57B28.87B26.20B26.03B26.86B23.65B
Gross Profit24.99B23.53B21.21B21.54B21.53B18.46B
EBITDA6.11B6.11B6.98B6.69B19.87B5.66B
Net Income3.87B3.50B2.33B2.54B14.61B2.77B
Balance Sheet
Total Assets74.89B65.41B63.60B64.06B60.54B47.21B
Cash, Cash Equivalents and Short-Term Investments19.82B14.60B14.12B16.92B15.79B16.43B
Total Debt11.96B9.78B12.58B13.98B12.12B14.21B
Total Liabilities29.12B22.63B25.43B26.12B22.81B24.79B
Stockholders Equity33.37B31.96B30.47B29.75B30.29B16.75B
Cash Flow
Free Cash Flow2.89B5.22B4.36B4.56B3.47B3.47B
Operating Cash Flow3.16B6.62B6.07B6.27B5.37B5.33B
Investing Cash Flow-7.29B-1.71B-756.98M-4.07B-2.52B-7.85B
Financing Cash Flow1.58B-6.32B-6.55B-3.19B-3.23B2.23B

Sino Biopharmaceutical Technical Analysis

Technical Analysis Sentiment
Negative
Last Price6.99
Price Trends
50DMA
7.96
Negative
100DMA
7.20
Negative
200DMA
5.39
Positive
Market Momentum
MACD
-0.28
Positive
RSI
38.26
Neutral
STOCH
42.01
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For HK:1177, the sentiment is Negative. The current price of 6.99 is below the 20-day moving average (MA) of 7.35, below the 50-day MA of 7.96, and above the 200-day MA of 5.39, indicating a neutral trend. The MACD of -0.28 indicates Positive momentum. The RSI at 38.26 is Neutral, neither overbought nor oversold. The STOCH value of 42.01 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Negative sentiment for HK:1177.

Sino Biopharmaceutical Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
72
Outperform
$141.38B31.209.79%16.90%63.11%
68
Neutral
$72.78B27.9815.34%0.84%7.51%44.09%
55
Neutral
$148.82B116.928.41%52.78%
54
Neutral
$124.66B31.2311.72%1.29%13.69%50.71%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
43
Neutral
HK$102.43B-109.23-14.40%33.46%-7.60%
43
Neutral
HK$39.44B-25.46-15.06%39.02%48.26%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
HK:1177
Sino Biopharmaceutical
6.99
3.53
101.91%
HK:1801
Innovent Biologics
88.05
50.60
135.11%
HK:1530
3SBio
30.30
24.32
406.60%
HK:2269
Wuxi Biologics (Cayman)
34.96
17.42
99.32%
HK:9926
Akeso, Inc.
114.00
47.65
71.82%
HK:1877
Shanghai Junshi Biosciences Co., Ltd. Class H
25.80
12.06
87.77%

Sino Biopharmaceutical Corporate Events

Sino Biopharmaceutical’s Culmerciclib Shows Promising Results in Phase III Breast Cancer Study
Oct 20, 2025

Sino Biopharmaceutical has announced positive interim results from its Phase III clinical study of culmerciclib, a CDK2/4/6 inhibitor, in combination with fulvestrant for the first-line treatment of HR+/HER2-advanced breast cancer. The study, presented at the ESMO Congress 2025, demonstrated significant efficacy in delaying disease progression and improving response rates compared to the control group, with manageable safety profiles. These results position culmerciclib as a potential best-in-class therapy, enhancing the company’s standing in the oncology sector and offering promising implications for stakeholders.

The most recent analyst rating on (HK:1177) stock is a Hold with a HK$8.00 price target. To see the full list of analyst forecasts on Sino Biopharmaceutical stock, see the HK:1177 Stock Forecast page.

Sino Biopharmaceutical’s TQ-B3234 Gains Breakthrough Therapy Designation
Oct 15, 2025

Sino Biopharmaceutical Limited announced that its new drug, TQ-B3234, a selective MEK1/2 inhibitor, has been included in the Breakthrough Therapy Designation process by the Center for Drug Evaluation of China’s National Medical Products Administration. This inclusion is for the treatment of adult plexiform neurofibromas associated with neurofibromatosis type I, a condition with significant unmet medical needs in China. The drug has shown promising results in clinical trials, with high rates of tumor shrinkage and good tolerability, and its inclusion in the Breakthrough Therapy Designation process is expected to accelerate its launch, potentially benefiting more patients sooner.

The most recent analyst rating on (HK:1177) stock is a Hold with a HK$8.00 price target. To see the full list of analyst forecasts on Sino Biopharmaceutical stock, see the HK:1177 Stock Forecast page.

Sino Biopharmaceutical’s TQB2102 Gains Breakthrough Designation in China
Oct 13, 2025

Sino Biopharmaceutical Limited announced that its drug TQB2102, a HER2 bispecific antibody-drug conjugate, has been included in China’s Breakthrough Therapeutic Designation process. This inclusion is expected to expedite the drug’s approval, offering a promising treatment for HER2 IHC 3+ advanced colorectal cancer, a condition with limited effective treatment options. The drug has shown a 34.8% objective response rate in clinical trials, indicating significant potential to improve patient outcomes in a field where current therapies have limited efficacy.

The most recent analyst rating on (HK:1177) stock is a Hold with a HK$8.00 price target. To see the full list of analyst forecasts on Sino Biopharmaceutical stock, see the HK:1177 Stock Forecast page.

Sino Biopharmaceutical Advances LM-350 Clinical Trials in Australia
Sep 25, 2025

Sino Biopharmaceutical Limited has announced the successful enrollment of the first patient in a Phase I clinical trial in Australia for its innovative drug, LM-350, a CDH17 antibody-drug conjugate developed by its subsidiary, LaNova Medicines. This marks a significant step in the clinical development of LM-350, which targets gastrointestinal tumors with high CDH17 expression, addressing unmet clinical needs in cancers such as colorectal, gastric, pancreatic, and esophageal. The trial aims to evaluate the safety, tolerability, and preliminary efficacy of LM-350, with hopes of advancing treatment options for patients with advanced solid tumors.

The most recent analyst rating on (HK:1177) stock is a Buy with a HK$9.80 price target. To see the full list of analyst forecasts on Sino Biopharmaceutical stock, see the HK:1177 Stock Forecast page.

Sino Biopharmaceutical Advances Innovative Cancer Therapy with Phase I Trial
Sep 23, 2025

Sino Biopharmaceutical Limited has announced the successful enrollment of the first patient in a Phase I clinical trial for LM-2417, a NaPi2b/4-1BB bispecific antibody, marking a significant step in its clinical development. This innovative therapy, developed by LaNova Medicines, targets NaPi2b, a promising anti-tumor target, and aims to enhance anti-tumor effects while minimizing toxicity. The trial will evaluate the safety and efficacy of LM-2417 as a monotherapy or in combination with other drugs, potentially positioning it as a First-in-Class immunotherapy.

The most recent analyst rating on (HK:1177) stock is a Buy with a HK$9.80 price target. To see the full list of analyst forecasts on Sino Biopharmaceutical stock, see the HK:1177 Stock Forecast page.

Sino Biopharmaceutical’s Innovative Diabetes Drug Gains Regulatory Acceptance
Sep 22, 2025

Sino Biopharmaceutical Limited announced that its Investigational New Drug (IND) application for TQF3250, an innovative oral GLP-1 receptor agonist for type 2 diabetes, has been accepted by China’s National Medical Products Administration. The drug shows promising preclinical results, offering significant advantages in patient compliance and safety over existing injectable formulations. With the global GLP-1RA market expected to grow significantly, the acceptance of TQF3250 positions the company to potentially capture a share of this expanding market.

The most recent analyst rating on (HK:1177) stock is a Buy with a HK$9.80 price target. To see the full list of analyst forecasts on Sino Biopharmaceutical stock, see the HK:1177 Stock Forecast page.

Sino Biopharmaceutical Gains Approval for Groundbreaking Lung Cancer Drug in China
Aug 29, 2025

Sino Biopharmaceutical Limited announced the approval of its zongertinib tablets, branded as Hernexeos®, for marketing in mainland China. This drug, developed in collaboration with Boehringer Ingelheim, is the first approved oral HER2 tyrosine kinase inhibitor for treating adult patients with unresectable locally advanced or metastatic non-small cell lung cancer (NSCLC) with HER2 mutations. The approval is based on positive results from the Beamion-LUNG 1 study, showing high efficacy and a manageable safety profile. This development addresses significant unmet clinical needs in lung cancer treatment in China and enhances the company’s oncology product line.

The most recent analyst rating on (HK:1177) stock is a Buy with a HK$9.17 price target. To see the full list of analyst forecasts on Sino Biopharmaceutical stock, see the HK:1177 Stock Forecast page.

Sino Biopharmaceutical Advances Respiratory Drug Portfolio with Promising Study Results
Aug 25, 2025

Sino Biopharmaceutical Limited announced the presentation of data from four studies on their respiratory drugs at the 2025 European Respiratory Society Annual Meeting. The studies include TQC3721, a PDE3/4 inhibitor with bronchodilatory and anti-inflammatory effects, which has been granted Breakthrough Therapy Designation in China and is in Phase III trials. TQC2731, a TSLP monoclonal antibody, is progressing rapidly in trials for asthma and other inflammatory diseases. TQC3403, a combination of umeclidinium bromide and vilanterol, is set to become the first marketed generic version in China, expected by 2026. These developments highlight Sino Biopharmaceutical’s strong positioning in the respiratory drug market and potential impact on stakeholders.

The most recent analyst rating on (HK:1177) stock is a Buy with a HK$9.17 price target. To see the full list of analyst forecasts on Sino Biopharmaceutical stock, see the HK:1177 Stock Forecast page.

Sino Biopharmaceutical’s Zongertinib Gains Breakthrough Designation in China
Aug 20, 2025

Sino Biopharmaceutical Limited announced that its HER2-selective tyrosine kinase inhibitor, zongertinib, has been granted Breakthrough Therapeutic Designation by the Center for Drug Evaluation in China for treating unresectable or metastatic non-small cell lung cancer with HER2 mutations. This designation, supported by clinical trial results, highlights the potential of zongertinib to address the unmet need for targeted therapies in this patient population. The company’s strategic partnership with Boehringer Ingelheim aims to enhance cancer treatment options in China, leveraging both companies’ strengths to bring innovative oncology products to market.

The most recent analyst rating on (HK:1177) stock is a Buy with a HK$9.17 price target. To see the full list of analyst forecasts on Sino Biopharmaceutical stock, see the HK:1177 Stock Forecast page.

Sino Biopharmaceutical’s LM-302 Drug Gains Breakthrough Designation in China
Aug 19, 2025

Sino Biopharmaceutical Limited has announced that its innovative drug, LM-302 ‘CLDN18.2 ADC’, developed by its subsidiary LaNova Medicines, has been included in China’s Breakthrough Therapeutic Designation process. This drug, used in combination with a PD-1 monoclonal antibody, shows promise as a first-line therapy for certain advanced cancers. Recent clinical trials have demonstrated significant efficacy and manageable safety, with high response and disease control rates. The inclusion in the BTD process is expected to expedite the drug’s market availability, offering a new treatment option for patients with CLDN18.2-positive gastric cancer.

The most recent analyst rating on (HK:1177) stock is a Buy with a HK$6.19 price target. To see the full list of analyst forecasts on Sino Biopharmaceutical stock, see the HK:1177 Stock Forecast page.

Sino Biopharmaceutical Reports Strong Growth in 2025 Earnings
Aug 19, 2025

Sino Biopharmaceutical Limited is a leading pharmaceutical conglomerate in China, known for its innovative R&D-driven approach and a fully-integrated industrial chain that spans various therapeutic areas such as oncology, liver/metabolic diseases, respiratory, and surgery/analgesia. The company is listed on the Hong Kong Stock Exchange and has been recognized among the top global pharmaceutical enterprises.

Sino Biopharmaceutical Declares Interim Dividend for 2025
Aug 19, 2025

Sino Biopharmaceutical Limited announced an interim cash dividend of HKD 0.05 per share for the financial year ending December 31, 2025. The ex-dividend date is set for August 29, 2025, with the payment date scheduled for September 23, 2025. This announcement reflects the company’s ongoing commitment to returning value to its shareholders and may enhance its attractiveness to investors.

The most recent analyst rating on (HK:1177) stock is a Buy with a HK$6.19 price target. To see the full list of analyst forecasts on Sino Biopharmaceutical stock, see the HK:1177 Stock Forecast page.

Sino Biopharmaceutical Reports Strong Interim Financial Results for 2025
Aug 18, 2025

Sino Biopharmaceutical reported a significant financial performance for the first half of 2025, with a 10.7% increase in revenue to RMB 17.57 billion and a 140.2% rise in profit attributable to owners from continuing operations. This growth was driven by increased sales of innovative products and higher dividend income. The company’s strategic focus on innovative therapies and its robust market presence continue to strengthen its position in the pharmaceutical industry.

The most recent analyst rating on (HK:1177) stock is a Buy with a HK$6.19 price target. To see the full list of analyst forecasts on Sino Biopharmaceutical stock, see the HK:1177 Stock Forecast page.

Sino Biopharmaceutical’s Innovative Cancer Drug TQB3142 Gains NMPA Approval for Clinical Trials
Aug 12, 2025

Sino Biopharmaceutical Limited announced that its Investigational New Drug application for TQB3142, a novel PROTAC molecule targeting Bcl-xL protein for the treatment of malignant tumors, has been accepted by China’s National Medical Products Administration. This innovative drug is designed to induce apoptosis in tumor cells with a reduced risk of platelet toxicity, offering a promising new treatment option in a field where no Bcl-xL inhibitors are currently approved worldwide.

The most recent analyst rating on (HK:1177) stock is a Buy with a HK$6.19 price target. To see the full list of analyst forecasts on Sino Biopharmaceutical stock, see the HK:1177 Stock Forecast page.

Sino Biopharmaceutical’s TQB3122 IND Application Accepted by NMPA
Aug 11, 2025

Sino Biopharmaceutical Limited announced that its Investigational New Drug application for TQB3122, a PARP1 inhibitor designed for treating advanced malignant tumors, has been accepted by China’s National Medical Products Administration. This innovative drug shows promise due to its high selectivity and ability to penetrate the blood-brain barrier, potentially offering new treatment options for intracranial tumors. The acceptance of this application marks a significant step for the company, as there are currently no approved drugs worldwide targeting the same mechanism, positioning Sino Biopharmaceutical as a potential leader in this niche market.

The most recent analyst rating on (HK:1177) stock is a Buy with a HK$6.19 price target. To see the full list of analyst forecasts on Sino Biopharmaceutical stock, see the HK:1177 Stock Forecast page.

Sino Biopharmaceutical’s Phase II Trial for Innovative Cancer Drug Approved
Aug 7, 2025

Sino Biopharmaceutical Limited has announced that its subsidiary, LaNova Medicines, has received approval from China’s National Medical Products Administration to conduct Phase II clinical trials for LM-24C5, a CEACAM5/4-1BB bispecific antibody. This innovative drug targets CEACAM5-positive advanced solid tumors and shows promise in enhancing anti-tumor activity by redirecting immune cells to the tumor microenvironment. The approval marks a significant step in the company’s efforts to develop a First-in-Class immunotherapy, potentially strengthening its position in the oncology treatment market.

The most recent analyst rating on (HK:1177) stock is a Buy with a HK$6.19 price target. To see the full list of analyst forecasts on Sino Biopharmaceutical stock, see the HK:1177 Stock Forecast page.

Sino Biopharmaceutical’s Rovadicitinib Gains Breakthrough Designation for cGVHD
Aug 6, 2025

Sino Biopharmaceutical announced that its independently developed Rovadicitinib Tablet, a JAK/ROCK inhibitor, has been included in the Breakthrough Therapeutic Designation process by China’s National Medical Products Administration for treating chronic graft-versus-host disease (cGVHD). This development marks a significant milestone as Rovadicitinib progresses through Phase III clinical trials in China and Phase II trials in the U.S., showcasing promising results in earlier trials with high response and survival rates. The company aims to expedite global R&D efforts to provide better treatment solutions for patients worldwide.

The most recent analyst rating on (HK:1177) stock is a Buy with a HK$6.19 price target. To see the full list of analyst forecasts on Sino Biopharmaceutical stock, see the HK:1177 Stock Forecast page.

Sino Biopharmaceutical’s TQC3302 Receives Clinical Trial Approval
Aug 5, 2025

Sino Biopharmaceutical Limited announced that its new drug, TQC3302, a triple-combination soft mist inhalation formulation for chronic obstructive pulmonary disease (COPD), has received clinical trial approval from China’s National Medical Products Administration. This development marks a significant step in the company’s efforts to provide advanced treatment options for COPD patients, as no similar formulation has been approved globally, potentially enhancing the company’s market position and offering new opportunities for stakeholders.

The most recent analyst rating on (HK:1177) stock is a Buy with a HK$6.19 price target. To see the full list of analyst forecasts on Sino Biopharmaceutical stock, see the HK:1177 Stock Forecast page.

Sino Biopharmaceutical Schedules Board Meeting for Interim Results and Dividend Consideration
Aug 1, 2025

Sino Biopharmaceutical Limited has announced a board meeting scheduled for August 18, 2025, to approve the publication of its unaudited interim results for the first half of 2025 and to consider the payment of an interim dividend. This meeting could impact the company’s financial strategy and shareholder returns, reflecting its ongoing operational and financial planning.

The most recent analyst rating on (HK:1177) stock is a Buy with a HK$6.19 price target. To see the full list of analyst forecasts on Sino Biopharmaceutical stock, see the HK:1177 Stock Forecast page.

Sino Biopharmaceutical to Receive $300 Million Milestone Payment from Merck Collaboration
Jul 30, 2025

Sino Biopharmaceutical Limited announced that its subsidiary, LaNova Medicines, is progressing smoothly with its out-licensing collaboration with Merck & Co., Inc. for the LM-299/MK-2010 PD-1/VEGF Bispecific Antibody. The company is set to receive a US$300 million milestone payment following the successful technology transfer. This collaboration, which grants Merck exclusive global rights for LM-299, includes an upfront payment of US$588 million and potential milestone payments up to US$2.7 billion, highlighting Sino Biopharmaceutical’s strategic positioning in the global pharmaceutical market.

The most recent analyst rating on (HK:1177) stock is a Buy with a HK$6.19 price target. To see the full list of analyst forecasts on Sino Biopharmaceutical stock, see the HK:1177 Stock Forecast page.

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Oct 24, 2025