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Akeso, Inc. (9926) AI Stock Analysis

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HK:9926

Akeso, Inc.

(HKEX:9926)

Select Model
Rating:48Neutral
Price Target:HKD 80.00â–¼(-1.84% Downside)
Action:reiterated
Date:10/15/26

The score is weighed down primarily by deteriorating profitability and negative operating/free cash flow despite strong revenue growth and high gross margins. Technicals add caution with the stock trading below key moving averages, while valuation is constrained by losses (negative P/E) and no dividend support.

Positive Factors
Revenue and Gross MarginThe strong 2025 revenue rebound, combined with consistently high gross margins, indicates meaningful commercial potential in Akeso’s biologic portfolio. If growth continues, this gross-profit structure can provide resources to support development, commercialization, and partnership expansion despite current losses.
Negative Factors
Persistent Net LossesThe shift from profit in 2023 to sizable losses in 2024–2025 shows that current operating expenses and development investment are not yet supported by earnings. Persistent negative margins could limit internal funding capacity and make future profitability dependent on successful clinical and commercial execution.

Akeso, Inc. (9926) vs. iShares MSCI Hong Kong ETF (EWH)

-30%-20%-10%0%10%20%30%40%HK:9926-26.71%EWH+7.37%Dec '25Jan '26Feb '26Mar '26Apr '26May '26Jun '26Jul '26Aug '26Sep '26Oct '26
Market Cap
HKD 75.07B
Dividend Yield
―
Average Volume (3M)
11.45M
Price to Earnings (P/E)
-66.5
Beta (1Y)
0.42
Revenue Growth
42.47%
EPS Growth
-15.80%
Country
Hong Kong
Employees
4,082
Sector
Healthcare
Sector Strength
51
Industry
Biotechnology

Akeso, Inc. Business Overview & Revenue Model

Company Description

Akeso, Inc. is a biopharmaceutical enterprise dedicated to the discovery, development, manufacturing, and commercialization of therapeutic solutions. The company boasts a diverse pipeline, with a significant focus on oncology. Its cancer-focused trea...

How the Company Makes Money

Akeso makes money primarily through (1) product sales of any therapies it commercializes itself (where revenue is recognized from selling approved drugs into the market through its commercial channels), and (2) collaboration and licensing arrangement...

Akeso, Inc. Financial Statement Overview

Summary

Strong 2025 revenue rebound and very high gross margins are positives, but profitability has deteriorated into sizable losses (2024–2025) and cash flow has weakened materially. Balance sheet leverage looks moderate, yet rising debt alongside negative operating and free cash flow increases funding risk.

Income Statement

54Neutral

Balance Sheet

63Positive

Cash Flow

42Neutral
Financial statement breakdown
BreakdownTTMDec 2025Dec 2024Dec 2023Dec 2022Dec 2021
Income Statement
Total Revenue3.40B2.98B2.12B4.53B837.66M225.63M
Gross Profit2.58B2.34B1.83B4.39B734.54M195.41M
EBITDA-779.43M-656.33M-536.34M2.17B-1.27B-1.31B
Net Income-952.25M-1.08B-514.51M2.03B-1.17B-1.07B
Balance Sheet
Total Assets16.22B16.01B12.75B9.18B5.50B4.81B
Cash, Cash Equivalents and Short-Term Investments9.16B9.18B7.32B4.88B2.29B2.65B
Total Debt4.98B4.56B3.95B2.99B1.88B859.42M
Total Liabilities7.86B7.06B6.00B4.66B2.95B1.53B
Stockholders Equity8.48B9.05B6.81B4.69B2.64B3.16B
Cash Flow
Free Cash Flow-1.24B-1.83B-1.11B1.59B-2.02B-1.71B
Operating Cash Flow-629.47M-1.11B-527.62M2.47B-1.24B-1.00B
Investing Cash Flow-3.30B-4.17B-1.52B-4.00B-889.75M-579.59M
Financing Cash Flow3.53B3.72B3.39B960.89M1.49B1.59B

Akeso, Inc. Technical Analysis

Technical Analysis SentimentNegative
Last Price81.50

Price Trends

50DMA94.69Negative
100DMA94.31Negative
200DMA106.64Negative

Market Momentum

MACD-4.37Positive
RSI37.11Neutral
STOCH22.69Neutral

Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For HK:9926, the sentiment is Negative. The current price of 81.50 is below the 20-day moving average (MA) of 95.29, below the 50-day MA of 94.69, and below the 200-day MA of 106.64, indicating a bearish trend. The MACD of -4.37 indicates Positive momentum. The RSI at 37.11 is Neutral, neither overbought nor oversold. The STOCH value of 22.69 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Negative sentiment for HK:9926.

Akeso, Inc. Peers Comparison

Overall Rating

UnderperformOutperform
Sector (51)

Financial Indicators

HK:9926 against its peers
NameOverall RatingMarket CapP/E RatioROEDividend YieldRevenue GrowthEPS Growth
HK:1801HK:180181OutperformHKD 139.32B95.596.06%―42.64%9.67%
HK:9995HK:999566NeutralHKD 51.82B7.89105.60%―292.84%―
HK:2696HK:269665NeutralHKD 26.75B26.1820.41%―32.63%8.74%
Sector *51Neutral$7.86B-0.30-43.30%2.27%22.53%-2.21%
HK:9926HK:992648NeutralHKD 76.70B-66.50-10.86%―42.47%-15.80%
HK:9688HK:968846NeutralHKD 21.69B-12.70-27.40%―5.38%16.86%
HK:1877HK:187741NeutralHKD 30.07B-69.15-7.23%―35.82%54.40%

* Healthcare Sector Average

Performance Comparison

-40%-20%0%20%HK:9926HK:1801HK:9688HK:9995HK:1877HK:2696Dec '25Jan '26Feb '26Mar '26Apr '26May '26Jun '26Jul '26Aug '26Sep '26Oct '26
HK:9926 and its peers over the selected period
Show on chartTickerCompany NamePriceChange% Change
HK:9926Akeso, Inc.81.50-36.80-31.11%
HK:1801Innovent Biologics79.75-10.45-11.59%
HK:9688Zai Lab Ltd17.37-3.65-17.36%
HK:9995RemeGen Co. Ltd. Class H64.85-28.00-30.16%
HK:1877Shanghai Junshi Biosciences Co., Ltd. Class H15.26-11.44-42.85%
HK:2696Shanghai Henlius Biotech, Inc. Class H49.06-20.04-29.00%

Akeso, Inc. Corporate Events

Akeso’s Ivonescimab Delivers Phase III Survival Gains in Biliary Tract Cancer

Oct 26, 2026

Akeso has reported late-breaking Phase III data from its HARMONi-GI1 trial, showing ivonescimab plus chemotherapy significantly improved survival outcomes versus durvalumab plus chemotherapy in first-line treatment of advanced biliary tract cancer. T...

Akeso Raises HK$1.94 Billion Through Institutional Share Placing

Oct 16, 2026

Akeso, Inc. has completed a placing of 20,000,000 new shares under its general mandate, executed by a sole coordinator and bookrunner. The shares were placed at HK$97.76 each to at least six independent professional and institutional investors, expan...

Akeso to Raise HK$1.94 Billion via Discounted Share Placing

Oct 13, 2026

Akeso, Inc. has entered into a placing agreement to issue 20,000,000 new shares at HK$97.76 each to at least six institutional or professional investors, representing about 2.17% of its existing share capital. The placing price reflects a discount of...

Akeso’s Ivonescimab Tops Pembrolizumab in Key Lung Cancer Survival Trial

Sep 2, 2026

Akeso, Inc. reported that its PD-1/VEGF bispecific antibody ivonescimab delivered a statistically significant and clinically meaningful overall survival benefit over Merck’s pembrolizumab in the Phase III HARMONi-2 trial. The study, involving 3...

Akeso Narrows Interim Loss as Revenue Jumps Nearly 28%

Aug 27, 2026

Akeso, Inc. reported that its revenue for the six months ended June 30, 2026 rose 27.92% year-on-year to RMB1,805.7 million, driven mainly by a 28.65% increase in commercial sales to RMB1,803.2 million and a modest contribution from license income. G...

Akeso’s Ivonescimab Delivers Phase III Survival Gain in Biliary Tract Cancer

Aug 25, 2026

Akeso, Inc., a Hong Kong-listed biopharmaceutical developer, has built its oncology franchise around ivonescimab, a first-in-class PD-1/VEGF bispecific antibody. The drug already has multiple approved and reimbursed indications in non-small cell lung...

Akeso Schedules Board Meeting to Approve 2026 Interim Results

Aug 17, 2026

Akeso, Inc. has scheduled a board meeting for August 27, 2026, to review and approve the interim results for the six months ended June 30, 2026, and to authorize their publication. The announcement signals the upcoming disclosure of the company&#8217...

Akeso Wins Third NMPA Nod for Ivonescimab in Advanced Lung Cancer

Aug 12, 2026

Akeso has secured National Medical Products Administration approval in China for a third major indication of its bi-specific antibody ivonescimab, branded 依達方, as a first-line treatment in combination with chemotherapy for advanc...

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.

Date of analysis: Oct 15, 2026