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Foghorn Therapeutics (FHTX) AI Stock Analysis

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FHTX

Foghorn Therapeutics

(NASDAQ:FHTX)

Select Model
Rating:42Neutral
Price Target:$2.00▲(4.99% Upside)
Action:reiterated
Date:10/03/26

The score is held down primarily by weak financial performance—large ongoing losses, negative equity, and significant cash burn—combined with very bearish technicals (price well below major moving averages and negative momentum). Valuation provides limited support due to losses (negative P/E) and no dividend, while corporate events are mixed: a discontinued collaboration program is a setback, partially offset by cost cuts aimed at extending runway.

Positive Factors
Proprietary drug-discovery platformFoghorn’s proprietary chromatin-regulatory platform provides a differentiated foundation for discovering genetically defined cancer therapies. Its focus on selective degraders and induced-proximity approaches could support multiple programs, allowing platform value to extend beyond any single clinical candidate over the next several quarters.
Negative Factors
Persistent losses and cash burnLarge recurring losses and substantial operating cash outflows show that Foghorn’s development model currently consumes capital faster than it generates sustainable earnings. Continued burn can force additional financing or program prioritization, potentially limiting flexibility and creating dilution or funding risk.

Foghorn Therapeutics (FHTX) vs. SPDR S&P 500 ETF (SPY)

-75%-50%-25%0%25%50%75%FHTX-56.90%SPY+10.42%Dec '25Jan '26Feb '26Mar '26Apr '26May '26Jun '26Jul '26Aug '26Sep '26Oct '26Nov '26
Market Cap
$113.13M
Dividend Yield
―
Average Volume (3M)
760.93K
Price to Earnings (P/E)
-1.9
Beta (1Y)
1.74
Revenue Growth
51.98%
EPS Growth
17.68%
Country
US
Employees
106
Sector
Healthcare
Sector Strength
51
Industry
Biotechnology

Foghorn Therapeutics Business Overview & Revenue Model

Company Description

Foghorn Therapeutics Inc. is a clinical-stage biopharmaceutical company dedicated to discovering and developing medicines. Their focus is on addressing genetically determined vulnerabilities within the chromatin regulatory system. The company employs...

How the Company Makes Money

Foghorn Therapeutics does not primarily generate revenue from commercial product sales because it is a clinical-stage company and, to the extent publicly disclosed, has no approved products on the market. Its revenue, when reported, is primarily deri...

Foghorn Therapeutics Financial Statement Overview

Summary

Despite ~30% TTM revenue growth to ~$36.7M, the company remains deeply unprofitable (TTM net loss ~-$64.6M; net margin ~-267%) with TTM gross profit turning slightly negative. Balance-sheet risk is elevated due to negative stockholders’ equity (~-$81.0M TTM) alongside meaningful debt (~$43.1M), and cash burn is heavy (TTM operating cash flow ~-$84.2M; free cash flow ~-$84.3M), implying continued dependence on external funding.

Income Statement

23Negative

Balance Sheet

18Very Negative

Cash Flow

20Very Negative
Financial statement breakdown
BreakdownTTMDec 2025Dec 2024Dec 2023Dec 2022Dec 2021
Income Statement
Total Revenue36.74M30.91M22.60M34.16M19.23M1.32M
Gross Profit15.70M27.58M22.60M34.16M19.23M1.32M
EBITDA-62.46M-70.95M-97.17M-90.75M-105.56M-96.19M
Net Income-64.58M-74.28M-86.62M-98.43M-108.88M-101.32M
Balance Sheet
Total Assets203.39M198.10M283.98M285.92M404.88M519.77M
Cash, Cash Equivalents and Short-Term Investments167.58M158.89M243.75M234.06M345.80M154.29M
Total Debt43.10M41.27M37.13M45.07M51.51M58.33M
Total Liabilities284.43M306.60M329.51M363.11M404.77M422.90M
Stockholders Equity-81.04M-108.50M-45.53M-77.19M112.00K96.87M
Cash Flow
Free Cash Flow-85.35M-86.15M-101.31M-119.33M192.40M-53.56M
Operating Cash Flow-85.30M-86.10M-100.41M-118.11M193.61M-50.25M
Investing Cash Flow28.12M112.04M-29.90M144.45M-244.32M36.17M
Financing Cash Flow608.00K1.02M105.43M1.78M1.76M22.42M

Foghorn Therapeutics Technical Analysis

Technical Analysis SentimentNegative
Last Price1.91

Price Trends

50DMA3.22Negative
100DMA4.33Negative
200DMA4.63Negative

Market Momentum

MACD-0.29Negative
RSI26.78Positive
STOCH49.22Neutral

Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For FHTX, the sentiment is Negative. The current price of 1.91 is below the 20-day moving average (MA) of 2.00, below the 50-day MA of 3.22, and below the 200-day MA of 4.63, indicating a bearish trend. The MACD of -0.29 indicates Negative momentum. The RSI at 26.78 is Positive, neither overbought nor oversold. The STOCH value of 49.22 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Negative sentiment for FHTX.

Foghorn Therapeutics Risk Analysis

Foghorn Therapeutics disclosed 54 risk factors in its most recent earnings report. Foghorn Therapeutics reported the most risks in the "Tech & Innovation" category.

Higher RiskSector Avg.Lower RiskFinance & CorporateTech & InnovationLegal & RegulatoryProductionAbility to SellMacro & Political
Tech & Innovation - Risks related to the company’s reliance on technology and ability to make innovative products

Latest Risks Added

1 New Risk
1..For a discussion of potential risks or uncertainties, please see “Risk Factors” in our Annual Report on Form 10-K for the fiscal year ended December 31, 2025. There have been no material changes to the risk factors disclosed in our Annual Report on Form 10-K for the fiscal year ended December 31, 2025.Q2, 2026

Foghorn Therapeutics Peers Comparison

Overall Rating

UnderperformOutperform
Sector (51)

Financial Indicators

FHTX against its peers
NameOverall RatingMarket CapP/E RatioROEDividend YieldRevenue GrowthEPS Growth
Sector *51Neutral$7.86B-0.30-43.30%2.27%22.53%-2.21%
FULCFULC51Neutral$287.64M-3.04-28.54%――0.04%
CCCCCCCC45Neutral$383.84M-4.10-37.71%―2.33%36.86%
ALXOALXO42Neutral$188.06M-1.02-90.30%――48.20%
FHTXFHTX42Neutral$124.71M-1.9272.64%―51.98%17.68%
ZNTLZNTL40Underperform$166.62M-0.69-87.95%―-100.00%14.08%
KPTIKPTI39Underperform$1.65M-0.0077.63%―6.81%11.95%

* Healthcare Sector Average

Performance Comparison

0%200%400%FHTXKPTIFULCZNTLALXOCCCCDec '25Jan '26Feb '26Mar '26Apr '26May '26Jun '26Jul '26Aug '26Sep '26Oct '26Nov '26
FHTX and its peers over the selected period
Show on chartTickerCompany NamePriceChange% Change
FHTXFoghorn Therapeutics, Inc.1.91-2.46-56.31%
KPTIKaryopharm Therapeutics INC0.06-5.10-98.84%
FULCFulcrum Therapeutics3.68-3.95-51.77%
ZNTLZentalis Pharmaceuticals Inc1.710.4333.59%
ALXOAlx Oncology Holdings, Inc.1.15-0.23-16.67%
CCCCC4 Therapeutics, Inc.2.950.6126.07%

Foghorn Therapeutics Corporate Events

Business Operations and StrategyProduct-Related Announcements

Foghorn Therapeutics Announces Major Strategic Reprioritization, Layoffs

Negative
Oct 1, 2026

On September 25, 2026, Foghorn Therapeutics and Eli Lilly decided not to advance FHD-909, a Phase 1 SMARCA2-targeting program, into the expansion phase and ended further collaboration activities, after the SMARCA2/4 synthetic lethality strategy faile...

Business Operations and StrategyFinancial Disclosures

Foghorn Therapeutics Reports Q2 Results and Pipeline Progress

Positive
Aug 6, 2026

On August 6, 2026, Foghorn Therapeutics reported second-quarter 2026 results and a corporate update, highlighting progress across its oncology and immunology pipeline and collaboration with Eli Lilly. The company’s Phase 1 trial of SMARCA2 inhi...

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.

Date of analysis: Oct 03, 2026