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Alterity Therapeutics Ltd (ATHE)
NASDAQ:ATHE
US Market
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Alterity Therapeutics (ATHE) AI Stock Analysis

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ATHE

Alterity Therapeutics

(NASDAQ:ATHE)

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Neutral 56 (OpenAI - 4o)
Rating:56Neutral
Price Target:
$5.50
▲(22.77% Upside)
The overall stock score for Alterity Therapeutics is primarily impacted by its challenging financial performance, with persistent losses and negative cash flows posing significant risks. However, technical analysis indicates strong upward momentum, which partially offsets the negative financial outlook. The poor valuation due to a negative P/E ratio further depresses the score. Without earnings call insights or new corporate events, the score reflects the current financial and technical conditions.
Positive Factors
Strong Gross Margin
A strong gross margin indicates effective cost management in production, which can support future profitability if operating costs are controlled.
Low Leverage
Low leverage reduces financial risk, providing stability and flexibility to invest in R&D and strategic initiatives without high debt burdens.
Proprietary Compounds
Proprietary compounds in neurodegenerative treatment offer a competitive edge, potentially leading to successful partnerships and revenue streams.
Negative Factors
Declining Revenue
Declining revenue indicates challenges in market penetration or product adoption, which can hinder long-term growth and financial stability.
Persistent Losses
Persistent losses highlight ongoing operational inefficiencies and can strain resources, limiting the ability to invest in growth initiatives.
Negative Cash Flows
Negative cash flows suggest operational inefficiencies and reliance on external financing, which can impact long-term financial health.

Alterity Therapeutics (ATHE) vs. SPDR S&P 500 ETF (SPY)

Alterity Therapeutics Business Overview & Revenue Model

Company DescriptionAlterity Therapeutics Limited engages in the research and development of therapeutic drugs to treat Alzheimer's disease, Huntington disease, Parkinson's disease, and other neurological disorders in Australia. The company's lead drug candidate is ATH434 that has completed Phase I clinical trial for the treatment of Parkinson's disease. It is also developing PBT2 that has completed Phase IIa clinical trial to treat Alzheimer's disease. The company was formerly known as Prana Biotechnology Limited and changed its name to Alterity Therapeutics Limited in April 2019. Alterity Therapeutics Limited was incorporated in 1997 and is headquartered in Melbourne, Australia.
How the Company Makes MoneyAlterity Therapeutics makes money through a combination of research and development collaborations, licensing agreements, and potential sales of its proprietary drug candidates. Revenue is primarily generated through milestone payments and royalties from its partnerships with larger pharmaceutical companies. These partnerships are crucial as they provide financial support for the costly process of drug development and clinical trials. Additionally, Alterity may receive government grants or funding from non-profit organizations dedicated to advancing neurological research. The company's earnings are significantly influenced by the success of clinical trials and the subsequent approval and commercialization of its therapies.

Alterity Therapeutics Financial Statement Overview

Summary
Alterity Therapeutics faces significant financial challenges, as evidenced by declining revenues, persistent losses, and negative cash flows. Despite a strong gross margin, profitability is severely impacted by high operating costs. The company maintains low leverage, but declining equity suggests ongoing financial strain. Improved operational efficiency and revenue growth are crucial for financial stability.
Income Statement
45
Neutral
Alterity Therapeutics shows a declining revenue trend with revenue decreasing over the past year. The company has consistently faced operating losses, reflected in negative EBIT and net income margins. Gross profit margins remain positive, indicating some control over cost of goods sold, but overall profitability is hampered by high operating expenses.
Balance Sheet
50
Neutral
The balance sheet reveals a low debt-to-equity ratio, suggesting a conservative approach to leverage. However, the equity ratio has declined, indicating a reduction in shareholder equity relative to assets. Return on equity remains negative due to persistent losses, highlighting a challenge in delivering shareholder value.
Cash Flow
40
Negative
The cash flow statements depict negative free cash flows, indicating cash outflows in operations have not been offset by sufficient inflows. The operating cash flow to net income ratio suggests inefficiencies in converting income into cash. While financing activities have provided liquidity, reliance on external financing could pose risks.
BreakdownDec 2024Dec 2023Dec 2022Dec 2021Dec 2020
Income Statement
Total Revenue4.02M3.92M5.12M4.34M0.00
Gross Profit3.80M3.63M4.76M3.98M-112.43K
EBITDA-19.57M-17.51M-17.39M-19.36M-13.34M
Net Income-19.12M-13.81M-12.85M-15.31M-9.70M
Balance Sheet
Total Assets19.22M27.32M41.36M33.59M13.30M
Cash, Cash Equivalents and Short-Term Investments12.64M15.77M34.81M28.12M9.20M
Total Debt159.04K210.38K117.49K65.65K33.75K
Total Liabilities5.43M4.50M5.89M3.12M2.76M
Stockholders Equity13.80M22.81M35.47M30.47M10.55M
Cash Flow
Free Cash Flow-12.61M-20.04M-12.43M-17.34M-9.45M
Operating Cash Flow-12.61M-20.04M-12.34M-17.33M-9.43M
Investing Cash Flow-5.72K-36.46K-89.15K-10.47K-16.74K
Financing Cash Flow9.22M124.34K16.30M36.69M3.98M

Alterity Therapeutics Technical Analysis

Technical Analysis Sentiment
Negative
Last Price4.48
Price Trends
50DMA
5.05
Negative
100DMA
4.63
Negative
200DMA
3.99
Positive
Market Momentum
MACD
-0.15
Positive
RSI
36.65
Neutral
STOCH
15.75
Positive
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For ATHE, the sentiment is Negative. The current price of 4.48 is below the 20-day moving average (MA) of 4.90, below the 50-day MA of 5.05, and above the 200-day MA of 3.99, indicating a neutral trend. The MACD of -0.15 indicates Positive momentum. The RSI at 36.65 is Neutral, neither overbought nor oversold. The STOCH value of 15.75 is Positive, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Negative sentiment for ATHE.

Alterity Therapeutics Risk Analysis

Alterity Therapeutics disclosed 44 risk factors in its most recent earnings report. Alterity Therapeutics reported the most risks in the "Tech & Innovation" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

Alterity Therapeutics Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
56
Neutral
$78.80M-42.68%63.85%
49
Neutral
-5.550.00%0.00%0.00%
44
Neutral
51.14M-2.620.00%0.00%62.69%
41
Neutral
92.25M-1.080.00%-100.00%55.32%
27
Underperform
384.94M-4.890.00%0.00%0.66%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
ATHE
Alterity Therapeutics
4.48
3.24
261.29%
CNTB
Connect Biopharma Holdings
1.57
0.35
28.69%
IMA
ImageneBio
8.25
-12.03
-59.32%
IMRX
Immuneering
9.26
6.39
222.65%
IMMX
Immix Biopharma
2.19
0.51
30.36%
MAIA
MAIA Biotechnology, Inc.
1.55
-1.29
-45.42%
Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Jul 29, 2025