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Kalaris Therapeutics (KLRS)
NASDAQ:KLRS
US Market
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Kalaris Therapeutics (KLRS) AI Stock Analysis

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KLRS

Kalaris Therapeutics

(NASDAQ:KLRS)

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Neutral 41 (OpenAI - Gpt-5.6Sol)
Rating:41Neutral
Price Target:
$2.00
▼(-52.38% Downside)
Action:Reiterated
Date:10/24/26
Overall score reflects heavy financial strain from being pre-revenue with persistent losses and ongoing cash burn that is eroding equity, partially offset by low leverage. Technical signals add downside risk given a strong bearish trend and very weak momentum readings, while valuation provides limited support due to negative earnings and no dividend yield data.
Positive Factors
Low Leverage
Very low leverage limits refinancing and interest-burden risk while preserving more financial flexibility than a highly indebted clinical-stage company. This provides some capacity to prioritize research spending and manage obligations as development programs progress.
Negative Factors
No Commercial Revenue
The absence of commercial revenue means Kalaris currently lacks an internally generated revenue stream to support research, operations, or future expansion. Its financial outlook therefore remains dependent on successful development and eventual commercialization of drug candidates.
Read all positive and negative factors
Positive Factors
Negative Factors
Low Leverage
Very low leverage limits refinancing and interest-burden risk while preserving more financial flexibility than a highly indebted clinical-stage company. This provides some capacity to prioritize research spending and manage obligations as development programs progress.
Read all positive factors

Kalaris Therapeutics (KLRS) vs. SPDR S&P 500 ETF (SPY)

Kalaris Therapeutics Business Overview & Revenue Model

Company Description
Kalaris Therapeutics, Inc., a clinical-stage biopharmaceutical company, engages in the development and commercialization of treatments for prevalent retinal diseases. It develops TH103, a clinical-stage anti-vascular endothelial growth factor (VEG...
How the Company Makes Money
Kalaris Therapeutics does not appear to generate recurring revenue from commercialized products; its revenue model is typical of a clinical-stage biotech. Primary funding sources are expected to include capital raising (e.g., issuing equity and/or...

Kalaris Therapeutics Financial Statement Overview

Summary
Financial profile remains weak: the company is pre-revenue ($0 revenue) with large, persistent net losses (~$44.3M TTM) and negative free cash flow (~-$45.6M TTM) that is worsening slightly (~-7% FCF growth). A key offset is low leverage (debt-to-equity ~0.02; total debt ~$1.4M), but shrinking equity (~$113.3M in 2024 to ~$57.7M TTM) underscores ongoing cash burn and funding dependence.
Income Statement
18
Very Negative
Balance Sheet
62
Positive
Cash Flow
24
Negative
BreakdownTTMDec 2025Dec 2024Dec 2023Dec 2022Dec 2021
Income Statement
Total Revenue0.000.000.000.000.000.00
Gross Profit-20.00K-13.00K0.000.000.00-1.12M
EBITDA-45.10M-41.98M-58.77M-14.01M-15.25M-169.84M
Net Income-44.26M-43.44M-58.77M-14.70M-15.48M-171.96M
Balance Sheet
Total Assets99.54M121.74M118.55M3.33M3.90M286.59M
Cash, Cash Equivalents and Short-Term Investments93.54M117.98M118.29M3.17M3.06M248.12M
Total Debt1.40M1.45M0.000.003.25M30.07M
Total Liabilities41.87M42.92M5.24M48.35M34.17M61.33M
Stockholders Equity57.67M78.81M113.31M-45.02M-30.27M225.27M
Cash Flow
Free Cash Flow-45.63M-43.18M-67.70M-14.13M-9.78M-106.34M
Operating Cash Flow-45.43M-42.98M-67.70M-14.13M-9.78M-106.32M
Investing Cash Flow-49.90M-19.72M95.00M0.000.00185.98M
Financing Cash Flow50.08M159.61M21.00K14.24M12.78M232.00K

Kalaris Therapeutics Technical Analysis

Technical Analysis Sentiment
Negative
Last Price4.20
Price Trends
50DMA
3.07
Negative
100DMA
3.64
Negative
200DMA
5.51
Negative
Market Momentum
MACD
-0.35
Positive
RSI
25.12
Positive
STOCH
6.76
Positive
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For KLRS, the sentiment is Negative. The current price of 4.2 is above the 20-day moving average (MA) of 2.28, above the 50-day MA of 3.07, and below the 200-day MA of 5.51, indicating a bearish trend. The MACD of -0.35 indicates Positive momentum. The RSI at 25.12 is Positive, neither overbought nor oversold. The STOCH value of 6.76 is Positive, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Negative sentiment for KLRS.

Kalaris Therapeutics Risk Analysis

Kalaris Therapeutics disclosed 74 risk factors in its most recent earnings report. Kalaris Therapeutics reported the most risks in the "Finance & Corporate" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

Kalaris Therapeutics Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
52
Neutral
$5.74B-21.79-273.23%――-10.60%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
49
Neutral
$1.30B-5.67-37.99%―-27.15%23.10%
44
Neutral
$165.32M-1.05-181.73%―-64.32%25.83%
42
Neutral
$17.89M-0.76-60.32%――71.26%
41
Neutral
$40.62M-0.92-71.71%――73.44%
38
Underperform
$78.41M-1.62-94.14%―-0.11%-13.99%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
KLRS
Kalaris Therapeutics
2.01
-2.86
-58.73%
CHRS
Coherus Biosciences
1.16
-0.57
-32.95%
NKTR
Nektar Therapeutics
38.55
-21.08
-35.35%
CLLS
Cellectis SA
1.26
-2.37
-65.29%
MCRB
Seres Therapeutics
1.79
-15.10
-89.40%
KOD
Kodiak Sciences
97.04
78.11
412.63%
Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Oct 24, 2026