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Assembly Biosciences (ASMB)
NASDAQ:ASMB
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Assembly Biosciences (ASMB) AI Stock Analysis

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ASMB

Assembly Biosciences

(NASDAQ:ASMB)

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Neutral 50 (OpenAI - Gpt-5.6Sol)
Rating:50Neutral
Price Target:
$23.00
▼(-34.90% Downside)
Action:Reiterated
Date:09/16/26
The score is driven primarily by mixed financial performance: a very strong, low-leverage balance sheet and sharply improved income statement are offset by continued, material cash burn. Technicals add meaningful downside pressure given the clear downtrend versus major moving averages and weak momentum readings. Valuation is also a headwind due to a high P/E and no dividend yield provided.
Positive Factors
Revenue Scale and Gross Margin
Revenue has scaled sharply from prior years while maintaining a strong gross margin, indicating meaningful economic value in the company’s current activities. If this revenue base persists, it can provide greater capacity to support research investment and improve operating leverage as development programs advance.
Negative Factors
Persistent Cash Burn
Materially negative operating and free cash flow shows that the business is not yet self-funding its activities. Continued cash burn can consume financial resources needed for clinical development and may eventually require additional financing, even with a strong balance sheet and near-breakeven net income.
Read all positive and negative factors
Positive Factors
Negative Factors
Revenue Scale and Gross Margin
Revenue has scaled sharply from prior years while maintaining a strong gross margin, indicating meaningful economic value in the company’s current activities. If this revenue base persists, it can provide greater capacity to support research investment and improve operating leverage as development programs advance.
Read all positive factors

Assembly Biosciences (ASMB) vs. SPDR S&P 500 ETF (SPY)

Assembly Biosciences Business Overview & Revenue Model

Company Description
Assembly Biosciences, Inc. is a biotechnology firm in the clinical development phase, dedicated to identifying and advancing innovative therapeutic solutions for hepatitis B virus (HBV) infections within the United States. Its primary drug candida...

Assembly Biosciences Financial Statement Overview

Summary
Financials are mixed. Revenue has scaled materially to ~$74.8M TTM with strong gross margin (~78%) and net income near breakeven, and the balance sheet is a major strength with minimal leverage (debt-to-equity ~0.008). However, operating profitability remains negative and cash flow is the key risk with materially negative operating cash flow and free cash flow (about -$38.5M and -$38.6M TTM), indicating ongoing cash burn.
Income Statement
54
Neutral
Balance Sheet
83
Very Positive
Cash Flow
32
Negative
BreakdownTTMDec 2025Dec 2024Dec 2023Dec 2022Dec 2021
Income Statement
Total Revenue74.84M72.30M28.52M7.16M0.006.25M
Gross Profit58.18M72.17M-27.41M-41.74M-69.08M6.25M
EBITDA68.00K-5.99M-39.72M-60.74M-92.52M-90.58M
Net Income-42.00K-6.12M-40.18M-61.23M-93.09M-129.85M
Balance Sheet
Total Assets330.83M257.59M119.17M136.82M101.79M191.06M
Cash, Cash Equivalents and Short-Term Investments320.36M248.11M112.08M130.25M91.61M146.63M
Total Debt2.35M2.63M3.09M2.34M3.46M6.48M
Total Liabilities25.18M50.84M85.81M95.73M19.13M22.13M
Stockholders Equity305.65M206.75M33.36M41.10M82.66M168.93M
Cash Flow
Free Cash Flow-38.57M-41.16M-51.15M22.49M-84.56M-96.49M
Operating Cash Flow-38.48M-41.09M-51.12M22.74M-84.46M-93.40M
Investing Cash Flow-234.51M-113.47M40.17M-69.14M90.64M26.52M
Financing Cash Flow281.27M174.67M29.45M13.82M614.00K53.06M

Assembly Biosciences Technical Analysis

Technical Analysis Sentiment
Negative
Last Price35.33
Price Trends
50DMA
28.44
Negative
100DMA
27.14
Negative
200DMA
27.97
Negative
Market Momentum
MACD
-1.93
Negative
RSI
25.87
Positive
STOCH
44.15
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For ASMB, the sentiment is Negative. The current price of 35.33 is above the 20-day moving average (MA) of 23.57, above the 50-day MA of 28.44, and above the 200-day MA of 27.97, indicating a bearish trend. The MACD of -1.93 indicates Negative momentum. The RSI at 25.87 is Positive, neither overbought nor oversold. The STOCH value of 44.15 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Negative sentiment for ASMB.

Assembly Biosciences Risk Analysis

Assembly Biosciences disclosed 30 risk factors in its most recent earnings report. Assembly Biosciences reported the most risks in the "Tech & Innovation" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

Assembly Biosciences Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
54
Neutral
$750.73M-3.30-106.15%――10.96%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
50
Neutral
$463.61M36.98-0.02%―125.12%98.69%
48
Neutral
$297.68M-3.04-47.12%―-52.96%30.51%
48
Neutral
$249.55M-2.38-41.85%――64.51%
45
Neutral
$316.39M-8.81-28.41%0.12%―14.04%
41
Neutral
$1.17B-0.06-91.63%――69.48%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
ASMB
Assembly Biosciences
20.34
-8.05
-28.36%
BNTC
Benitec Biopharma
8.63
-6.43
-42.70%
ANNX
Annexon Biosciences
3.83
0.83
27.67%
QSI
Quantum-Si
1.41
-0.74
-34.42%
VOR
Vor Biopharma
19.06
-11.75
-38.14%
LXEO
Lexeo Therapeutics, Inc.
2.74
-5.76
-67.76%
Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Sep 16, 2026