Strong Vafseo Launch
Vafseo's US net product revenues reached $12 million, exceeding the guidance of $10 million to $11 million. The launch is described as one of the strongest in the dialysis market, with nearly 100% coverage from commercial contracts with dialysis organizations.
Increased Prescriber Base
The number of prescribers increased by nearly 25% compared to February, ending the quarter with over 640 prescribers.
Positive Refill and Prescription Trends
Refills constituted about one third of all prescriptions in Q1, indicating patient retention. Prescriptions per provider increased to approximately 12 from nearly eight.
Financial Performance
Total revenues increased to $57.3 million in Q1 2025 from $32.6 million in Q1 2024, driven by Vafseo and a 43% increase in Auryxia sales.
Reduced Cost of Goods Sold
Cost of goods sold decreased to $7.6 million from $11.6 million despite higher sales, due to the elimination of a $9 million non-cash amortization charge.
Strong Cash Position
The company ended Q1 with $113.4 million in cash and cash equivalents, bolstered by a public offering raising over $46 million.
Progress in Clinical Studies
The VOICE study is 75% enrolled, targeting 2200 subjects, and the Phase III VALOR trial for non-dialysis patients is on track to begin in the second half of 2025.