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Celldex Therapeutics Inc (CLDX)
NASDAQ:CLDX
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Celldex (CLDX) AI Stock Analysis

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CLDX

Celldex

(NASDAQ:CLDX)

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Neutral 51 (OpenAI - Gpt-5.6Sol)
Rating:51Neutral
Price Target:
$31.00
▼(-23.59% Downside)
Action:Reiterated
Date:09/24/26
The score is held back primarily by weak financial performance (widening losses, near-zero TTM revenue, and accelerating cash burn) and bearish technical trends (below major moving averages with negative MACD). Offsetting these risks are a strong, low-debt balance sheet and a major positive corporate catalyst from strong Phase 3 trial results.
Positive Factors
Phase 3 clinical validation
Strong Phase 3 results materially improve barzolvolimab’s development and potential commercialization outlook. Efficacy across difficult-to-treat patients, sustained responses, and favorable safety support regulatory progress and increase the program’s strategic importance over the next several quarters.
Negative Factors
Limited commercial revenue
Near-zero trailing revenue indicates Celldex is not yet supported by a durable commercial product base. Continued reliance on financing, collaborations, or other non-recurring sources can constrain operating independence and make future investment capacity dependent on external funding conditions.
Read all positive and negative factors
Positive Factors
Negative Factors
Phase 3 clinical validation
Strong Phase 3 results materially improve barzolvolimab’s development and potential commercialization outlook. Efficacy across difficult-to-treat patients, sustained responses, and favorable safety support regulatory progress and increase the program’s strategic importance over the next several quarters.
Read all positive factors

Celldex (CLDX) vs. SPDR S&P 500 ETF (SPY)

Celldex Business Overview & Revenue Model

Company Description
Celldex Therapeutics, Inc. is a biopharmaceutical company dedicated to developing antibody-based treatments, specifically monoclonal and bispecific antibodies, for a range of diseases. Their pipeline features therapeutic candidates aimed at both i...
How the Company Makes Money
Celldex does not primarily generate revenue from selling marketed drugs; instead, as a clinical-stage biotech, it funds operations mainly through financing activities and, when applicable, collaboration-related income. Material sources of cash and...

Celldex Financial Statement Overview

Summary
Overall fundamentals are constrained by very weak operating performance: persistent and widening losses, revenue collapsing to near-zero in TTM, and accelerating cash burn (negative operating cash flow and free cash flow). The main offset is a strong, low-debt balance sheet that reduces near-term solvency risk and provides financial flexibility.
Income Statement
18
Very Negative
Balance Sheet
82
Very Positive
Cash Flow
34
Negative
BreakdownTTMDec 2025Dec 2024Dec 2023Dec 2022Dec 2021
Income Statement
Total Revenue112.00K1.50M7.02M6.88M2.36M4.65M
Gross Profit-63.67M1.50M-156.53M-111.13M-79.90M-48.66M
EBITDA-297.20M-255.42M-154.69M-139.03M-104.20M-66.08M
Net Income-300.59M-258.80M-157.86M-141.43M-112.33M-70.51M
Balance Sheet
Total Assets782.35M582.98M792.34M465.63M352.74M444.65M
Cash, Cash Equivalents and Short-Term Investments717.59M518.57M725.28M421.70M304.95M408.25M
Total Debt4.90M2.34M3.81M2.54M4.03M3.04M
Total Liabilities67.78M55.82M45.34M36.46M26.53M25.18M
Stockholders Equity714.56M527.16M747.00M429.17M326.20M419.48M
Cash Flow
Free Cash Flow-241.82M-213.66M-159.70M-109.11M-105.56M-62.16M
Operating Cash Flow-235.57M-210.94M-157.78M-107.29M-103.73M-60.91M
Investing Cash Flow-67.13M209.07M-290.13M-105.78M89.94M-216.16M
Financing Cash Flow327.11M2.39M441.45M218.46M4.08M272.37M

Celldex Technical Analysis

Technical Analysis Sentiment
Negative
Last Price40.57
Price Trends
50DMA
38.29
Negative
100DMA
35.88
Negative
200DMA
32.33
Negative
Market Momentum
MACD
-2.10
Positive
RSI
30.59
Neutral
STOCH
16.64
Positive
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For CLDX, the sentiment is Negative. The current price of 40.57 is above the 20-day moving average (MA) of 35.53, above the 50-day MA of 38.29, and above the 200-day MA of 32.33, indicating a bearish trend. The MACD of -2.10 indicates Positive momentum. The RSI at 30.59 is Neutral, neither overbought nor oversold. The STOCH value of 16.64 is Positive, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Negative sentiment for CLDX.

Celldex Risk Analysis

Celldex disclosed 2 risk factors in its most recent earnings report. Celldex reported the most risks in the "Legal & Regulatory" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

Celldex Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
62
Neutral
$6.45B-20.31-40.51%―34.52%41.20%
62
Neutral
$1.96B-11.83-49.73%―1083.56%30.89%
59
Neutral
$2.42B-6.66-76.09%―-58.40%-31.99%
52
Neutral
$2.37B-8.23-50.56%―-100.00%18.12%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
51
Neutral
$2.53B-7.26-52.36%―-97.27%-44.90%
50
Neutral
$1.60B-6.50-37.99%―-27.15%23.10%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
CLDX
Celldex
31.65
5.24
19.84%
NKTR
Nektar Therapeutics
43.58
-16.97
-28.03%
IOVA
Iovance Biotherapeutics
14.22
11.88
507.48%
NRIX
Nurix Therapeutics
22.99
13.61
145.10%
NUVB
Nuvation Bio
5.14
1.43
38.54%
IMNM
Immunome
20.90
8.52
68.82%

Celldex Corporate Events

Business Operations and StrategyProduct-Related Announcements
Celldex reports strong Phase 3 data in urticaria
Positive
Sep 22, 2026
On September 22, 2026, Celldex reported positive topline data from its Phase 3 EMBARQ-CSU1 and EMBARQ-CSU2 trials of barzolvolimab in chronic spontaneous urticaria patients inadequately controlled by H1-antihistamines. Both studies, which together...
Business Operations and StrategyShareholder Meetings
Celldex Shareholders Approve Expanded Equity Incentive Plan
Positive
Jun 26, 2026
At its June 25, 2026 annual meeting, Celldex Therapeutics stockholders approved an amendment to the company’s 2021 Omnibus Equity Incentive Plan, increasing the shares available for issuance by 3,400,000 to a total of 12,900,000 and clarifyi...
Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Sep 24, 2026