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THNR

Amplify Weight Loss Drug & Treatment ETF (THNR)

Rating:62Neutral
Price Target:$27.00▲(8.33% Upside)

THNR’s rating suggests it is a reasonably solid but somewhat specialized ETF focused on weight loss drugs and related treatments, with its quality supported by large, established pharma leaders like AstraZeneca, Amgen, Eli Lilly, Novo Nordisk, Roche, Pfizer, and AbbVie that bring strong financial performance, product pipelines, and generally positive outlooks. The fund’s weaker spots come from earlier-stage or less consistently profitable names like Viking Therapeutics and Innovent Biologics, which add growth potential but also higher risk. The main risk factor is the ETF’s concentration in a single, highly specialized healthcare niche, where valuation concerns, high leverage at some holdings, and competitive pressures could increase volatility.

Positive Factors
Strong Recent PerformanceThe ETF has shown strong short-term gains over the last one and three months, suggesting positive recent momentum in its holdings.
Leading Health Care CompaniesSeveral top holdings, including major drug makers and biotechs, have delivered strong year-to-date performance, helping support the fund’s returns.
Global Exposure Within a Focused ThemeWhile the fund is mainly invested in U.S. companies, it also holds meaningful positions in Hong Kong and Japan, adding some international diversification to its weight-loss treatment focus.
Negative Factors
High Sector ConcentrationWith almost all assets in health care, the ETF is heavily exposed to risks specific to drug development, regulation, and sentiment toward weight-loss treatments.
Mixed Performance Among Top HoldingsA few large positions, such as Novo Nordisk and Regeneron, have shown weak year-to-date performance, which can drag on overall fund results.
Above-Average Expense RatioThe fund’s expense ratio is relatively high for an ETF, meaning more of investors’ returns are used to cover fees.

THNR vs. SPDR S&P 500 ETF (SPY)

AUM
5.76M
Region
Developed Markets
Expense Ratio
0.59%
Beta
0.64
Issuer
Amplify
Inception Date
May 21, 2024
Dividend Yield
1.66%
Asset Class
Equity
Index Tracked
VettaFi Weight Loss Drug & Treatment Index - Benchmark TR Net

THNR Summary

The Amplify Weight Loss Drug & Treatment ETF (THNR) is a fund that follows the VettaFi Weight Loss Drug & Treatment Index and focuses on health care companies working on weight loss drugs and related treatments. It mainly holds pharmaceutical and biotech firms, including well-known names like Novo Nordisk and Eli Lilly, which make popular weight loss and diabetes medications. Someone might invest in this ETF to seek growth from the rising demand for obesity and weight management treatments and to get diversified exposure to many companies in this niche. A key risk is that it is heavily concentrated in health care and can rise or fall sharply with news about drug approvals, regulations, or medical breakthroughs.

How much will it cost me?

The Amplify Weight Loss Drug & Treatment ETF (THNR) has an expense ratio of 0.59%, meaning you’ll pay $5.90 per year for every $1,000 invested. This is higher than average for ETFs because it is actively managed and focuses on a specialized niche in the health care sector. Actively managed funds typically have higher costs due to the research and expertise required to select investments.

What would affect this ETF?

The Amplify Weight Loss Drug & Treatment ETF (THNR) could benefit from growing global awareness of obesity-related health issues and increased demand for innovative weight loss treatments, especially as its top holdings include major pharmaceutical companies like Eli Lilly and Novo Nordisk, which are leaders in this space. However, the ETF may face challenges from regulatory hurdles, competition in drug development, or economic downturns that could reduce consumer spending on health care solutions. Additionally, its heavy reliance on the health care sector makes it vulnerable to sector-specific risks, such as changes in government policies or patent expirations.

THNR Top 10 Holdings

THNR is essentially a bet on the global weight-loss and obesity-treatment boom, with Eli Lilly and Novo Nordisk acting as the main engines of the story—though Novo has been lagging lately, taking a bit of shine off the theme. Amgen and AbbVie add steady, rising support from the big pharma side, while Viking Therapeutics brings more volatile, early-stage biotech flavor that can swing results. With nearly all exposure in health care and a mix of U.S., European, and Hong Kong names, the fund is both thematically tight and geographically diversified.

THNR top ten holdings
NameCompany NameWeight %Market ValueMarket CapYearly GainOverall Rating
LLYLLYEli Lilly & Co11.22%$645.68K$1.21T58.93%72Outperform
NVONVONovo Nordisk8.78%$505.06K$174.26B-28.70%73Outperform
AMGNAMGNAmgen6.01%$345.88K$236.98B45.56%77Outperform
ABBVABBVAbbVie5.77%$332.15K$510.84B23.08%66Neutral
RHHVFRHHVFRoche Holding AG――――73Outperform
PFEPFEPfizer5.70%$328.08K$171.62B20.12%74Outperform
GILDGILDGilead Sciences5.50%$316.78K$194.07B23.77%78Outperform
AZNAZNAstraZeneca――――80Outperform
REGNREGNRegeneron5.33%$306.84K$83.13B39.07%78Outperform
HK:1093HK:1093CSPC Pharmaceutical Group5.17%$297.78KHKD 102.61B-2.47%63Neutral

THNR Technical Analysis

Technical Analysis SentimentNeutral
Last Price24.92

Price Trends

50DMA25.80Negative
100DMA25.56Negative
200DMA25.36Negative

Market Momentum

MACD-0.29Negative
RSI48.92Neutral
STOCH85.86Negative

Evaluating momentum and price trends is crucial in ETF analysis to make informed investment decisions. For THNR, the sentiment is Neutral. The current price of 24.92 is above the 20-day moving average (MA) of 24.74, below the 50-day MA of 25.80, and below the 200-day MA of 25.36, indicating a neutral trend. The MACD of -0.29 indicates Negative momentum. The RSI at 48.92 is Neutral, neither overbought nor oversold. The STOCH value of 85.86 is Negative, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Neutral sentiment for THNR.

THNR Peer Comparison

Comparison Results

THNR against its peer funds
NamePricePrice TargetAUMExpense RatioOverall Rating
THNRTHNR$24.92$27.00(8.33% Upside)$5.76M0.59%62Neutral
AGNGAGNG$37.96$42.75(12.62% Upside)$92.69M0.50%64Neutral
FDIQFDIQ$74.23$85.01(14.52% Upside)$41.92M0.35%73Outperform
WISEWISE$32.60$65.90(102.17% Upside)$23.01M0.35%57Neutral
IVEPIVEP$24.40$34.60(41.82% Upside)$14.39M0.75%70Outperform
FOWFFOWF$34.28$45.61(33.07% Upside)$14.51M0.49%70Neutral

Performance Comparison

-20%0%20%THNRAGNGFDIQWISEIVEPFOWFNov '25Dec '25Jan '26Feb '26Mar '26Apr '26May '26Jun '26Jul '26Aug '26Sep '26Oct '26
THNR and its peers over the selected period
Show on chartTickerCompany NamePriceChange% Change
THNRAmplify Weight Loss Drug & Treatment ETF24.922.139.36%
AGNGGlobal X Aging Population ETF37.954.1812.39%
FDIQInvesco Bloomberg Financial Data Providers ETF74.2317.8031.55%
WISEThemes Generative Artificial Intelligence ETF32.60-10.37-24.13%
IVEPDan IVES Wedbush AI Power & Infrastructure ETF24.40-1.70-6.51%
FOWFPacer Solactive Whitney Future of Warfare ETF34.272.969.45%
Glossary
BuyAn ETF rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the ETF is likely to deliver higher returns compared to other ETFs in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldAn ETF rated as a "Hold" s expected to perform in line with the overall market or a specific benchmark. This rating indicates that the ETF is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellAn ETF rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the ETF may deliver lower returns compared to other ETFs in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
Disclaimer

This AI Analyst ETF Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in ETFs carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.