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Tempest Therapeutics (TPST)
NASDAQ:TPST
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Tempest Therapeutics (TPST) AI Stock Analysis

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TPST

Tempest Therapeutics

(NASDAQ:TPST)

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Neutral 44 (OpenAI - Gpt-5.6Sol)
Rating:44Neutral
Price Target:
$0.80
▼(-25.56% Downside)
Action:Reiterated
Date:09/29/26
The score is held down primarily by weak financial performance (pre-revenue, ongoing losses/cash burn, and negative equity) and bearish technical trends. Corporate events provide some offset through added financing flexibility and CAR-T collaboration progress, but dilution and governance execution risks remain material, and valuation metrics offer limited support for a loss-making biotech.
Positive Factors
Flexible funding access
The equity facility gives Tempest discretion to raise capital over time rather than requiring one immediate issuance. This can improve funding flexibility for clinical development and operations, although access remains dependent on equity-market conditions and shareholder dilution.
Negative Factors
Pre-revenue operating model
Tempest has no product-sales revenue to offset research and development spending, leaving its financial outlook dependent on clinical progress, partnerships, or future commercialization. Persistent losses make profitability uncertain and reduce the business’s ability to fund growth internally.
Read all positive and negative factors
Positive Factors
Negative Factors
Flexible funding access
The equity facility gives Tempest discretion to raise capital over time rather than requiring one immediate issuance. This can improve funding flexibility for clinical development and operations, although access remains dependent on equity-market conditions and shareholder dilution.
Read all positive factors

Tempest Therapeutics (TPST) vs. SPDR S&P 500 ETF (SPY)

Tempest Therapeutics Business Overview & Revenue Model

Company Description
Tempest Therapeutics Inc. is an oncology company, currently in the clinical development phase, dedicated to advancing novel small molecule drugs designed to combat cancer. The firm's pipeline highlights two key therapeutic candidates: TPST-1495, a...
How the Company Makes Money
Tempest Therapeutics is a clinical-stage biotech and does not primarily operate a mature product-sales business. Its cash generation typically comes from (a) collaboration and licensing arrangements (e.g., upfront payments, research funding or cos...

Tempest Therapeutics Financial Statement Overview

Summary
Very weak fundamentals typical of an early-stage biotech: zero revenue, persistent and sizable net losses, and ongoing cash burn. While debt is relatively low, stockholders’ equity turning negative in the TTM period is a key balance-sheet risk that raises financing/dilution concerns.
Income Statement
12
Very Negative
Balance Sheet
18
Very Negative
Cash Flow
20
Very Negative
BreakdownTTMDec 2025Dec 2024Dec 2023Dec 2022Dec 2021
Income Statement
Total Revenue0.000.000.000.000.000.00
Gross Profit-22.18M0.00-389.00K0.000.000.00
EBITDA-40.29M-25.79M-40.14M-27.66M-33.45M-26.65M
Net Income-40.47M-26.26M-41.84M-29.49M-35.71M-28.30M
Balance Sheet
Total Assets9.63M16.93M41.49M51.60M46.09M73.24M
Cash, Cash Equivalents and Short-Term Investments779.00K7.71M30.27M39.23M31.23M51.83M
Total Debt7.56M8.14M15.37M20.66M22.11M18.54M
Total Liabilities10.72M10.26M22.36M24.84M27.98M37.12M
Stockholders Equity-1.09M6.67M19.13M26.77M18.11M36.12M
Cash Flow
Free Cash Flow-20.73M-26.82M-33.46M-27.53M-31.63M-26.09M
Operating Cash Flow-20.73M-26.82M-33.03M-27.36M-31.07M-25.96M
Investing Cash Flow0.000.00-435.00K-170.00K-562.00K-97.00K
Financing Cash Flow7.23M4.26M24.50M35.60M11.40M59.06M

Tempest Therapeutics Technical Analysis

Technical Analysis Sentiment
Negative
Last Price1.08
Price Trends
50DMA
0.97
Negative
100DMA
1.15
Negative
200DMA
1.74
Negative
Market Momentum
MACD
-0.05
Positive
RSI
44.48
Neutral
STOCH
15.90
Positive
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For TPST, the sentiment is Negative. The current price of 1.08 is above the 20-day moving average (MA) of 0.89, above the 50-day MA of 0.97, and below the 200-day MA of 1.74, indicating a bearish trend. The MACD of -0.05 indicates Positive momentum. The RSI at 44.48 is Neutral, neither overbought nor oversold. The STOCH value of 15.90 is Positive, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Negative sentiment for TPST.

Tempest Therapeutics Risk Analysis

Tempest Therapeutics disclosed 79 risk factors in its most recent earnings report. Tempest Therapeutics reported the most risks in the "Tech & Innovation" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

Tempest Therapeutics Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
60
Neutral
$35.84M3.1183.42%―――
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
49
Neutral
$41.58M-1.17-708.20%――30.16%
44
Neutral
$13.69M-0.19-1270.11%――69.34%
43
Neutral
$13.87M-0.62-456.35%――9.68%
42
Neutral
$10.99M-0.233398.40%――15.37%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
TPST
Tempest Therapeutics
0.81
-9.96
-92.52%
ATNM
Actinium Pharmaceuticals
1.15
-0.45
-28.13%
PDSB
PDS Biotechnology
0.71
-0.31
-30.78%
LTRN
Lantern Pharma
1.00
-3.02
-75.12%
CALC
CalciMedica
1.65
-13.60
-89.18%

Tempest Therapeutics Corporate Events

Business Operations and StrategyExecutive/Board ChangesRegulatory Filings and Compliance
Tempest Therapeutics Strengthens Governance and CAR-T Partnership Framework
Positive
Sep 28, 2026
On Sept. 22, 2026, Tempest Therapeutics entered into a Master Services Agreement with related-party Factor Bioscience Inc. to provide research and development services, including Work Order No. 1 for in vivo CAR-T therapy development, with expecte...
Business Operations and StrategyProduct-Related Announcements
Tempest Therapeutics Expands In Vivo CAR-T Collaboration
Positive
Sep 17, 2026
On September 14, 2026, Tempest Therapeutics entered an exclusive collaboration, option and license agreement with Hebei Senlang Biotechnology that grants Tempest a four-month exclusive option to license Senlang’s CD7-targeted lentiviral in v...
Business Operations and StrategyShareholder Meetings
Tempest Therapeutics Adjourns Meeting on Governance Changes
Negative
Sep 16, 2026
On September 15, 2026, Tempest Therapeutics reconvened a special shareholder meeting originally held on July 27 and August 17, 2026, to seek approval for an amendment to its Restated Certificate of Incorporation that would replace certain supermaj...
Business Operations and StrategyPrivate Placements and FinancingRegulatory Filings and Compliance
Tempest Therapeutics Announces New Private Warrant Financing
Positive
Sep 15, 2026
On September 11, 2026, Tempest Therapeutics entered into a securities purchase agreement with an institutional investor for a private placement of pre-funded warrants and Series C and D common stock warrants, raising approximately $2.5 million in ...
Business Operations and StrategyExecutive/Board Changes
Tempest Therapeutics Announces New Chief Financial Officer
Neutral
Aug 24, 2026
On August 18, 2026, Tempest Therapeutics, Inc. disclosed that Principal Financial Officer and Principal Accounting Officer Justin Trojanowski had resigned from all his roles at the company, with the departure scheduled to take effect on September ...
Business Operations and StrategyShareholder Meetings
Tempest Therapeutics Adjourns Special Stockholder Meeting Again
Negative
Aug 18, 2026
On August 17, 2026, Tempest Therapeutics reconvened a special meeting of stockholders originally convened and adjourned on July 27, 2026, to seek approval of an amendment to its Restated Certificate of Incorporation that would replace certain supe...
Business Operations and StrategyPrivate Placements and Financing
Tempest Therapeutics Secures Flexible $50 Million Equity Facility
Positive
Aug 13, 2026
On August 13, 2026, Tempest Therapeutics entered into a purchase and registration rights agreement with Lincoln Park Capital Fund, under which Lincoln Park committed to buy up to $50 million of Tempest’s common stock over 24 months, starting...
Business Operations and StrategyShareholder Meetings
Tempest Therapeutics Adjourns Vote on Governance Changes
Neutral
Jul 28, 2026
On July 27, 2026, Tempest Therapeutics convened a special meeting of stockholders to seek approval of an amendment to its Restated Certificate of Incorporation that would eliminate certain supermajority voting requirements and allow stockholder ac...
Business Operations and StrategyProduct-Related Announcements
Tempest Therapeutics inks China in vivo CAR-T deal
Positive
Jul 22, 2026
On July 17, 2026, Tempest Therapeutics entered a collaboration agreement with Hebei Senlang Biotechnology to co-develop Tempest’s in vivo CAR-T product candidates in China, starting with TPST-4003. The deal positions Tempest to leverage Senl...
Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Sep 29, 2026