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CalciMedica (CALC)
NASDAQ:CALC
US Market
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CalciMedica (CALC) AI Stock Analysis

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CALC

CalciMedica

(NASDAQ:CALC)

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Neutral 45 (OpenAI - 5.2)
Rating:45Neutral
Price Target:
$0.74
▲(22.67% Upside)
Action:Reiterated
Date:06/09/26
The score is primarily pressured by weak financial fundamentals (no revenue, ongoing losses, heavy cash burn, and negative equity) and heightened listing-risk from Nasdaq deficiency notices. Technical indicators show some near-term momentum improvement, but longer-term trend measures remain weak, and valuation signals are limited due to negative earnings and no dividend.
Positive Factors
Targeted clinical-stage pipeline
CalciMedica's focused development of Auxora, a CRAC channel inhibitor targeting acute inflammatory and immunologic conditions, represents a clear, durable scientific strategy. A differentiated mechanism can create a sustainable competitive edge in niche high-unmet-need indications if clinical validation is achieved, concentrating R&D and partner interest over multiple quarters.
Negative Factors
Pre-revenue with heavy cash burn
With no product revenue and persistent operating and free cash flow burn near -$21M TTM, CalciMedica remains structurally dependent on external financing to fund development. This funding dependency increases dilution risk, creates execution pressure on clinical milestones, and makes the company vulnerable to tighter capital markets over the next several months.
Read all positive and negative factors
Positive Factors
Negative Factors
Targeted clinical-stage pipeline
CalciMedica's focused development of Auxora, a CRAC channel inhibitor targeting acute inflammatory and immunologic conditions, represents a clear, durable scientific strategy. A differentiated mechanism can create a sustainable competitive edge in niche high-unmet-need indications if clinical validation is achieved, concentrating R&D and partner interest over multiple quarters.
Read all positive factors

CalciMedica (CALC) vs. SPDR S&P 500 ETF (SPY)

CalciMedica Business Overview & Revenue Model

Company Description
CalciMedica, Inc., a clinical-stage biotechnology company headquartered in La Jolla, California, is focused on creating treatments for life-threatening inflammatory diseases that currently lack adequate therapies. The company's proprietary approac...
How the Company Makes Money
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CalciMedica Financial Statement Overview

Summary
Pre-revenue profile with $0 revenue, persistent operating losses, and sustained cash burn (TTM operating/free cash flow around -$21.2M). While net loss has improved and TTM debt is $0, stockholders’ equity is negative (TTM about -$1.1M), increasing financing and dilution risk.
Income Statement
12
Very Negative
Balance Sheet
18
Very Negative
Cash Flow
14
Very Negative
BreakdownTTMDec 2025Dec 2024Dec 2023Dec 2022Dec 2021
Income Statement
Total Revenue0.000.000.000.000.000.00
Gross Profit-7.00K0.000.000.000.00-519.00K
EBITDA-18.21M-28.09M-13.64M-34.19M-7.64M-35.30M
Net Income-19.54M-29.56M-13.70M-34.36M-7.82M-35.82M
Balance Sheet
Total Assets8.61M13.59M19.79M12.19M3.35M69.09M
Cash, Cash Equivalents and Short-Term Investments8.16M13.02M18.67M11.24M1.33M63.67M
Total Debt0.009.70M0.000.005.36M0.00
Total Liabilities9.71M20.23M5.38M4.03M12.58M4.07M
Stockholders Equity-1.10M-6.64M14.41M8.16M-9.23M65.02M
Cash Flow
Free Cash Flow-21.18M-21.21M-21.15M-25.81M-11.76M-31.99M
Operating Cash Flow-21.16M-21.18M-21.15M-25.73M-11.76M-31.50M
Investing Cash Flow12.29M9.55M-4.42M8.88M-4.00K10.75M
Financing Cash Flow4.47M15.21M27.97M20.90M8.48M695.00K

CalciMedica Technical Analysis

Technical Analysis Sentiment
Negative
Last Price0.60
Price Trends
50DMA
0.70
Positive
100DMA
0.73
Positive
200DMA
2.38
Negative
Market Momentum
MACD
0.04
Positive
RSI
46.02
Neutral
STOCH
11.22
Positive
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For CALC, the sentiment is Negative. The current price of 0.6 is below the 20-day moving average (MA) of 0.84, below the 50-day MA of 0.70, and below the 200-day MA of 2.38, indicating a neutral trend. The MACD of 0.04 indicates Positive momentum. The RSI at 46.02 is Neutral, neither overbought nor oversold. The STOCH value of 11.22 is Positive, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Negative sentiment for CALC.

CalciMedica Risk Analysis

CalciMedica disclosed 71 risk factors in its most recent earnings report. CalciMedica reported the most risks in the "Tech & Innovation" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

CalciMedica Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
52
Neutral
$48.36M-2.68-0.97%21.67%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
50
Neutral
$53.30M-1.59-346.03%28.53%
49
Neutral
$29.02M-0.56-503.79%82.28%
45
Neutral
$11.93M-0.58-526.36%16.33%
41
Neutral
$24.86M-0.49-217.27%-74.39%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
CALC
CalciMedica
0.76
-0.79
-50.97%
PDSB
PDS Biotechnology
0.96
-0.59
-37.99%
SKYE
Skye Bioscience
0.71
-2.16
-75.37%
LTRN
Lantern Pharma
3.79
0.72
23.45%
SNTI
Senti Biosciences
0.93
-1.06
-53.22%
Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Jun 09, 2026