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CalciMedica (CALC)
NASDAQ:CALC
US Market
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CalciMedica (CALC) AI Stock Analysis

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CALC

CalciMedica

(NASDAQ:CALC)

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Neutral 43 (OpenAI - Gpt-5.6Sol)
Rating:43Neutral
Price Target:
$0.62
▼(-18.95% Downside)
Action:Reiterated
Date:08/19/26
The score is held down primarily by weak financial performance (no revenue, sizable losses, and significant ongoing cash burn) and bearish technicals (price below key moving averages with negative MACD). Corporate events provide some support via extended funding runway and favorable FDA safety feedback, but dilution risk remains elevated and valuation signals are constrained by negative earnings.
Positive Factors
Improved Balance Sheet
No debt and positive equity reduce near-term leverage risk and provide a cleaner financial base for development activities. This improvement gives CalciMedica greater flexibility while it seeks clinical milestones and additional funding.
Negative Factors
Pre-Revenue Business Model
CalciMedica has no commercial product revenue to fund operations, while substantial losses continue. Until a program reaches commercialization or generates partnership income, the company remains dependent on clinical execution and external capital to sustain its business.
Read all positive and negative factors
Positive Factors
Negative Factors
Improved Balance Sheet
No debt and positive equity reduce near-term leverage risk and provide a cleaner financial base for development activities. This improvement gives CalciMedica greater flexibility while it seeks clinical milestones and additional funding.
Read all positive factors

CalciMedica (CALC) vs. SPDR S&P 500 ETF (SPY)

CalciMedica Business Overview & Revenue Model

Company Description
CalciMedica, Inc., a clinical-stage biotechnology company headquartered in La Jolla, California, is focused on creating treatments for life-threatening inflammatory diseases that currently lack adequate therapies. The company's proprietary approac...
How the Company Makes Money
As a clinical-stage biopharmaceutical company, CalciMedica does not have publicly established recurring product revenue from commercialized drugs. Its funding and cash inflows are therefore primarily driven by external financing and, when applicab...

CalciMedica Financial Statement Overview

Summary
Pre-revenue profile with persistent losses (TTM net loss about -$21.2M) and heavy cash burn (TTM FCF about -$19.1M). Positives include improved losses versus 2025 and a cleaner latest balance sheet with no debt and positive equity (~$5.5M), but ongoing funding needs and dilution risk remain high.
Income Statement
12
Very Negative
Balance Sheet
38
Negative
Cash Flow
14
Very Negative
BreakdownTTMDec 2025Dec 2024Dec 2023Dec 2022Dec 2021
Income Statement
Total Revenue0.000.000.000.000.000.00
Gross Profit-7.00K0.000.000.000.00-519.00K
EBITDA-19.91M-28.09M-13.64M-34.19M-7.64M-35.30M
Net Income-21.24M-29.56M-13.70M-34.36M-7.82M-35.82M
Balance Sheet
Total Assets19.50M13.59M19.79M12.19M3.35M69.09M
Cash, Cash Equivalents and Short-Term Investments18.62M13.02M18.67M11.24M1.33M63.67M
Total Debt0.009.70M0.000.005.36M0.00
Total Liabilities13.99M20.23M5.38M4.03M12.58M4.07M
Stockholders Equity5.51M-6.64M14.41M8.16M-9.23M65.02M
Cash Flow
Free Cash Flow-19.12M-21.21M-21.15M-25.81M-11.76M-31.99M
Operating Cash Flow-19.11M-21.18M-21.15M-25.73M-11.76M-31.50M
Investing Cash Flow12.20M9.55M-4.42M8.88M-4.00K10.75M
Financing Cash Flow19.60M15.21M27.97M20.90M8.48M695.00K

CalciMedica Technical Analysis

Technical Analysis Sentiment
Negative
Last Price0.76
Price Trends
50DMA
0.80
Negative
100DMA
0.73
Negative
200DMA
1.89
Negative
Market Momentum
MACD
-0.04
Positive
RSI
42.68
Neutral
STOCH
21.92
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For CALC, the sentiment is Negative. The current price of 0.76 is above the 20-day moving average (MA) of 0.72, below the 50-day MA of 0.80, and below the 200-day MA of 1.89, indicating a bearish trend. The MACD of -0.04 indicates Positive momentum. The RSI at 42.68 is Neutral, neither overbought nor oversold. The STOCH value of 21.92 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Negative sentiment for CALC.

CalciMedica Risk Analysis

CalciMedica disclosed 71 risk factors in its most recent earnings report. CalciMedica reported the most risks in the "Tech & Innovation" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

CalciMedica Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
54
Neutral
$33.24M-1.60-456.35%9.68%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
45
Neutral
$12.34M-0.34-346.03%30.16%
43
Neutral
$22.62M-0.484092.98%15.37%
43
Neutral
$14.70M-0.30-217.27%-19.08%
41
Neutral
$13.39M-0.24-503.79%80.28%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
CALC
CalciMedica
0.64
-2.14
-77.05%
PDSB
PDS Biotechnology
0.21
-0.96
-82.22%
SKYE
Skye Bioscience
0.36
-2.97
-89.22%
LTRN
Lantern Pharma
2.52
-1.94
-43.50%
SNTI
Senti Biosciences
0.43
-1.17
-73.13%

CalciMedica Corporate Events

Executive/Board Changes
CalciMedica Announces Board Expansion and Leadership Transition
Neutral
Jul 7, 2026
On July 2, 2026, CalciMedica’s board of directors expanded from seven to eight seats and appointed Evgeny Zaytsev, M.D., Ph.D., as a Class I director, with his term running until the 2027 annual meeting of stockholders. Zaytsev’s appoi...
Business Operations and StrategyPrivate Placements and FinancingRegulatory Filings and Compliance
CalciMedica Advances Auxora After Favorable FDA Safety Review
Positive
Jun 24, 2026
On June 23, 2026, CalciMedica entered into a securities purchase agreement for a private placement of 18,673,429 units of stock and warrants with institutional and accredited investors, including several insiders, at prices around $0.80 per unit. ...
Business Operations and StrategyPrivate Placements and Financing
CalciMedica Amends Loan, Issues New Equity Warrants
Positive
Jun 24, 2026
On June 23, 2026, CalciMedica amended its existing $10 million loan and security agreement with Avenue Venture Opportunities Fund II, extending the interest-only period by one year to September 30, 2027 and pushing the loan’s maturity to Sep...
Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Aug 19, 2026