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Supernus Pharmaceuticals (SUPN)
NASDAQ:SUPN

Supernus Pharmaceuticals (SUPN) AI Stock Analysis

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Supernus Pharmaceuticals

(NASDAQ:SUPN)

Rating:72Outperform
Price Target:
$36.00
▲(8.70%Upside)
Supernus Pharmaceuticals demonstrates strong financial stability and strategic growth through acquisitions. However, valuation concerns and technical indicators suggest caution. The company's growth in core products and strategic acquisitions are promising, but offset by challenges with legacy product declines and patent issues.
Positive Factors
Product Launch and Market Opportunity
The FDA has approved Onapgo (SC apomorphine pump) to treat OFF episodes in Parkinson's disease, offering a significant market opportunity.
Sales Performance
Qelbree solidly exceeded expectations, with $74.4MM in Q4 sales, reflecting solid demand.
Stock Price Target
The price target for Supernus Pharmaceuticals stock has been increased from $44.00 to $45.00.
Negative Factors
Clinical Trial Challenges
No subgroup profiles or specific data trends stood out in the SPN-820 trial, indicating potential challenges in differentiating treatment effects.
Clinical Trial Results
Disappointing Phase 2b data from SPN-820 in treatment-resistant patients led to a downgrade of the stock rating.

Supernus Pharmaceuticals (SUPN) vs. SPDR S&P 500 ETF (SPY)

Supernus Pharmaceuticals Business Overview & Revenue Model

Company DescriptionSupernus Pharmaceuticals, Inc., a biopharmaceutical company, focuses on the development and commercialization of products for the treatment of central nervous system (CNS) diseases in the United States. Its commercial products are Trokendi XR, an extended release topiramate product indicated for the treatment of epilepsy, as well as for the prophylaxis of migraine headache; and Oxtellar XR, an extended release oxcarbazepine for the monotherapy treatment of partial onset epilepsy seizures in adults and children between 6 to 17 years of age. The company's commercial products also comprise Qelbree, a selective norepinephrine reuptake inhibitor indicated for the treatment of attention-deficit hyperactivity disorder (ADHD) in pediatric patients 6 to 17 years of age; APOKYN for the acute intermittent treatment of hypomobility or off episodes in patients with advanced Parkinson's Disease (PD); XADAGO for treating levodopa/carbidopa in patients with PD experiencing off episodes; MYOBLOC, a Type B toxin product indicated for the treatment of cervical dystonia and sialorrhea in adults; GOCOVRI for the treatment of dyskinesia in patients with PD; and Osmolex ER for the treatment of Parkinson's disease and drug-induced extrapyramidal reaction in adult patients. In addition, its product candidates include Qelbree (SPN-812), which has completed Phase III clinical trials that is used for the treatment of ADHD; SPN-830, a late-stage drug/device combination product candidate for the prevention of off episodes in PD patients; SPN-817, a novel product candidate in Phase I clinical trials for the treatment of severe epilepsy; SPN-820, a product candidate in Phase II clinical trials for treating resistant depression; and SPN-443 and SPN-446, which are in preclinical stage for treating CNS. The company markets and sells its products through pharmaceutical wholesalers, specialty pharmacies, and distributors. The company was incorporated in 2005 and is headquartered in Rockville, Maryland.
How the Company Makes MoneySupernus Pharmaceuticals primarily generates revenue through the sales of its pharmaceutical products. The company's key revenue streams include product sales from its portfolio of CNS-related therapies, which are marketed directly to healthcare providers and sold through various distribution channels. Supernus also engages in strategic partnerships and collaborations with other pharmaceutical companies to expand its market reach and enhance its product offerings. Additionally, the company may receive milestone payments and royalties from licensing agreements related to its proprietary drug formulations and technologies. These combined efforts contribute to Supernus's earnings and financial growth.

Supernus Pharmaceuticals Earnings Call Summary

Earnings Call Date:May 06, 2025
(Q1-2025)
|
% Change Since: 2.13%|
Next Earnings Date:Jul 31, 2025
Earnings Call Sentiment Neutral
Supernus Pharmaceuticals demonstrated strong growth in core products Qelbree and GOCOVRI, introduced a promising new product ONAPGO, and maintained a solid cash position. However, these positives were offset by significant declines in legacy products and an increased operating loss, resulting in an overall net loss for the quarter.
Q1-2025 Updates
Positive Updates
Double-Digit Revenue Growth
Total revenues, excluding Trokendi XR and Oxtellar XR, increased by 26% in the first quarter compared to the same quarter last year.
Qelbree Performance
Qelbree grew by 22% in prescriptions and by 44% in net sales. Monthly prescriptions in March reached an all-time high of 75,277, up 25% compared to the same period last year.
GOCOVRI Growth
Prescriptions for GOCOVRI increased by 12% and net sales increased by 16% compared to the same quarter last year, with Medicare prescriptions costing patients less than $25 for 84% of prescriptions.
Launch of ONAPGO
Launched ONAPGO, a new growth product for Parkinson's disease, with initial positive response from physicians and more than 75% of sales territories generating patient enrollment forms.
Strong Cash Position
The company had approximately $463.6 million in cash, cash equivalents, and marketable securities, maintaining a strong balance sheet.
Negative Updates
Legacy Products Decline
Combined net sales of Trokendi XR and Oxtellar XR were down 46% for the first quarter, with expected further erosion in sales.
Operating Loss
Operating loss on a GAAP basis for the first quarter of 2025 was $10.3 million, compared to an operating loss of $3.2 million for the prior year period, largely due to higher contingent consideration loss.
GAAP Net Loss
GAAP net loss was $11.8 million for the first quarter of 2025, compared to net earnings of $124,000 in the prior year quarter.
Company Guidance
During Supernus Pharmaceuticals' first quarter 2025 financial results conference call, guidance was reiterated for the full year, projecting total revenues to range from $600 million to $630 million, driven primarily by net product sales and royalty revenue. The company maintained its estimates for combined R&D and SG&A expenses to be between $435 million and $460 million. Non-GAAP operating earnings are expected to range from $105 million to $130 million, while GAAP operating earnings are projected to vary from a $15 million loss to a $10 million profit. The call highlighted a 26% increase in total revenues, excluding legacy products Trokendi XR and Oxtellar XR, due to the strong performance of Qelbree and GOCOVRI. Qelbree saw a 22% rise in prescriptions and a 44% jump in net sales, while GOCOVRI experienced a 12% increase in prescriptions and 16% growth in net sales. For the remainder of 2025, combined net sales of Trokendi XR and Oxtellar XR are expected to decrease, with guidance maintained at $65 million to $75 million. Supernus also launched ONAPGO, a subcutaneous apomorphine infusion device for Parkinson's disease, which received encouraging initial feedback from physicians.

Supernus Pharmaceuticals Financial Statement Overview

Summary
Supernus Pharmaceuticals demonstrates a strong financial position, characterized by robust margins and a solid equity base. The company maintains low leverage, reducing financial risk while ensuring ample liquidity. Despite moderate revenue growth, stable cash flows and efficient cost management underscore its operational resilience. Opportunities exist to enhance shareholder returns through improved net income generation.
Income Statement
76
Positive
Supernus Pharmaceuticals demonstrated a solid gross profit margin of 79.5% in the TTM, indicating strong cost management. The net profit margin of 9.3% suggests reasonable profitability, despite a slight decline from the previous year. Revenue growth is relatively modest, reflecting stable but limited expansion opportunities. EBITDA margin is healthy at 25.0%, supporting operational efficiency.
Balance Sheet
82
Very Positive
The company exhibits a robust equity position with an equity ratio of 76.5% in the TTM, highlighting financial stability. The debt-to-equity ratio is low at 0.03, indicating minimal leverage and reduced financial risk. Return on equity is moderate at 6.0%, suggesting room for improvement in generating returns for shareholders.
Cash Flow
79
Positive
Operating cash flow remains strong with an operating cash flow to net income ratio of 2.65, indicating efficient cash generation relative to income. Free cash flow growth has been stable, supporting potential reinvestment or shareholder returns. However, the free cash flow to net income ratio of 2.64 suggests a balanced but not overly aggressive cash deployment strategy.
BreakdownTTMDec 2024Dec 2023Dec 2022Dec 2021Dec 2020
Income Statement
Total Revenue668.00M661.82M607.52M667.24M579.77M520.40M
Gross Profit531.00M583.91M523.74M580.02M504.71M467.94M
EBITDA166.97M178.28M90.04M153.44M129.19M212.40M
Net Income61.91M73.86M1.32M60.71M53.42M126.95M
Balance Sheet
Total Assets1.35B1.37B1.28B1.70B1.69B1.50B
Cash, Cash Equivalents and Short-Term Investments463.59M453.61M254.87M461.33M339.68M422.53M
Total Debt32.30M34.27M41.53M437.97M420.55M390.33M
Total Liabilities316.58M332.34M356.16M816.30M873.30M759.24M
Stockholders Equity1.03B1.04B921.52M886.20M815.85M744.86M
Cash Flow
Free Cash Flow163.34M171.23M110.53M116.41M125.08M134.95M
Operating Cash Flow164.15M171.95M111.08M116.83M127.13M138.40M
Investing Cash Flow-100.93M-189.87M268.73M-216.66M-81.91M-34.70M
Financing Cash Flow-10.78M12.19M-397.88M-10.48M-130.42M3.56M

Supernus Pharmaceuticals Technical Analysis

Technical Analysis Sentiment
Positive
Last Price33.12
Price Trends
50DMA
32.27
Positive
100DMA
32.22
Positive
200DMA
34.05
Negative
Market Momentum
MACD
0.09
Negative
RSI
59.91
Neutral
STOCH
79.14
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For SUPN, the sentiment is Positive. The current price of 33.12 is above the 20-day moving average (MA) of 32.10, above the 50-day MA of 32.27, and below the 200-day MA of 34.05, indicating a neutral trend. The MACD of 0.09 indicates Negative momentum. The RSI at 59.91 is Neutral, neither overbought nor oversold. The STOCH value of 79.14 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Positive sentiment for SUPN.

Supernus Pharmaceuticals Risk Analysis

Supernus Pharmaceuticals disclosed 56 risk factors in its most recent earnings report. Supernus Pharmaceuticals reported the most risks in the "Finance & Corporate" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

Supernus Pharmaceuticals Peers Comparison

Overall Rating
UnderperformOutperform
Sector (52)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
74
Outperform
$1.41B-5.19%30.26%-173.36%
72
Outperform
$1.86B29.996.32%11.82%
69
Neutral
$1.02B7.8619.90%8.05%-8.46%
63
Neutral
$2.61B106.97%13.42%92.50%
52
Neutral
$1.31B64.45-10.45%24.76%-783.38%
52
Neutral
$7.51B0.24-62.67%2.30%16.09%0.95%
EVEVO
49
Neutral
$1.49B-20.41%0.45%-125.61%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
SUPN
Supernus Pharmaceuticals
33.12
4.39
15.28%
DVAX
Dynavax
10.58
0.02
0.19%
ANIP
ANI Pharmaceuticals
64.96
1.74
2.75%
AMPH
Amphastar Pharmaceuticals
21.66
-17.10
-44.12%
EVO
Evotec AG
4.07
-0.80
-16.43%
AMRX
Amneal Pharmaceuticals
8.33
0.95
12.87%

Supernus Pharmaceuticals Corporate Events

Executive/Board ChangesShareholder Meetings
Supernus Pharmaceuticals Holds Annual Stockholders Meeting
Neutral
Jun 17, 2025

On June 16, 2025, Supernus Pharmaceuticals held its annual stockholders meeting, where key decisions were made regarding the election of directors, executive compensation, and the appointment of KPMG LLP as the independent public accounting firm for 2025. These decisions are expected to influence the company’s governance and financial oversight, impacting its strategic direction and stakeholder confidence.

The most recent analyst rating on (SUPN) stock is a Buy with a $40.00 price target. To see the full list of analyst forecasts on Supernus Pharmaceuticals stock, see the SUPN Stock Forecast page.

M&A Transactions
Supernus Pharmaceuticals to Acquire Sage Therapeutics
Positive
Jun 16, 2025

On June 13, 2025, Supernus Pharmaceuticals announced a definitive agreement to acquire Sage Therapeutics through a tender offer valued at approximately $795 million. This acquisition is expected to enhance Supernus’ neuropsychiatry product portfolio with the addition of ZURZUVAE, an FDA-approved treatment for postpartum depression, and is anticipated to be significantly accretive by 2026, with potential cost synergies of up to $200 million annually.

The most recent analyst rating on (SUPN) stock is a Buy with a $40.00 price target. To see the full list of analyst forecasts on Supernus Pharmaceuticals stock, see the SUPN Stock Forecast page.

Legal ProceedingsBusiness Operations and Strategy
Supernus Pharmaceuticals Faces Patent Challenges for Qelbree
Negative
May 28, 2025

On May 22 and 23, 2025, Supernus Pharmaceuticals received Paragraph IV Notice Letters indicating that third parties filed Abbreviated New Drug Applications (ANDAs) for viloxazine hydrochloride capsules, challenging the patents of their product Qelbree. Supernus plans to enforce its intellectual property rights, which are protected by six U.S. patents expiring between 2029 and 2035, potentially impacting its market position and stakeholder interests.

The most recent analyst rating on (SUPN) stock is a Buy with a $40.00 price target. To see the full list of analyst forecasts on Supernus Pharmaceuticals stock, see the SUPN Stock Forecast page.

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Jul 10, 2025