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Summit Therapeutics (SMMT) Stock Price & Analysis
SMMT Stock Chart & Stats
- Day’s Range
- $15.57 - $16.43
- 52-Week Range
- $12.07 - $29.23
- Previous Close
- $16.20
- Volume
- 4.23M
- Average Volume (3M)
- 6.17M
- Market Cap
- $12.82B
- Enterprise Value
- $10.67B
- Total Cash (Recent Filing)
- $690.68M
- Total Debt (Recent Filing)
- $20.38M
- Price to Earnings (P/E)
- ―
- Beta
- 2.01
- Next Earnings
- Nov 11, 2026 (Est.)
- EPS Estimate
- -0.28
- Next Dividend Ex-Date
- N/A
- Dividend Yield
- N/A
Bulls Say, Bears Say
Bulls Say
Phase III Clinical Efficacy
Consistent efficacy across multiple Phase III studies supports ivonescimab’s potential differentiation in oncology rather than reliance on a single trial. Repeated survival signals can strengthen regulatory, partnering, and commercial prospects across several cancer indications over the next several quarters.
Strategic AstraZeneca Partnership
A large strategic investment from AstraZeneca provides external validation of ivonescimab and strengthens Summit’s capitalization for late-stage development. The accompanying combination work also expands access to a major oncology partner and may improve the asset’s competitive positioning.
Broadening Oncology Pipeline
A broad, multi-indication development program gives Summit several potential paths to create long-term value from ivonescimab. Multiple trials and external collaborations diversify clinical opportunities, increase patient and investigator exposure, and support platform-like strategic relevance.
Bears Say
Pre-revenue And Large Losses
Without a meaningful revenue base, Summit’s financial outlook depends heavily on clinical and regulatory success rather than established commercial cash flows. Continued large losses limit earnings visibility and mean that any delay in development or approval could extend the period before profitability.
High And Rising Cash Burn
Heavy operating cash consumption reduces the time available to fund Summit’s extensive clinical program from existing resources. Rising trial and research spending can accelerate financing needs, increase execution pressure, and make sustained progress dependent on continued access to external capital.
Regulatory And Statistical Uncertainty
The pending FDA decision remains a material business risk because approval depends on an overall-survival standard that has not yet received agency feedback. Multiple interim analyses, differing regional maturity, and possible requests or delays could complicate interpretation and timing.
Summit Therapeutics News
Summit Therapeutics: Buy Rating Reaffirmed on Durable HARMONi-GI1 Survival Data; $43 Price Target Maintained
Analyst Yigal Nochomovitz from Citi maintained a Buy rating on Summit Therapeutics and keeping the price target at $43.00. Yigal Nochomovitz has given his Buy rating due to a combination
Summit’s partner announces results from Phase III HARMONi-GI1 study
Summit Therapeutics (SMMT) noted that its partner Akeso announced positive results from the Phase III HARMONi-GI1 study evaluating the novel, potential first-in-class investigational bispecific antibody ivonescimab plus chemotherapy compared with
Summit Therapeutics, Lunit announces research pact over Lunit SCOPE IO
Summit Therapeutics (SMMT) and Lunit announced a research agreement to evaluate the use of Lunit SCOPE IO, Lunit’s AI-powered pathology platform, for tumor microenvironment analysis in support of Summit’s immuno-oncology
Summit Therapeutics enters trial collaboration with ECOG-ACRIN
Summit Therapeutics (SMMT) announced a clinical trial collaboration with the ECOG-ACRIN Cancer Research Group to evaluate ivonescimab, a novel, potential first-in-class investigational bispecific antibody, in a registration-enabling Phase II/III study
Analyst Maintains Hold on Summit Amid AstraZeneca Partnership Benefits but Persistent Ivonescimab/ADC Clinical Uncertainties and No 12‑Month Target
H.C. Wainwright analyst Mitchell Kapoor has reiterated their neutral stance on SMMT stock, giving a Hold rating today. Mitchell Kapoor has given his Hold rating due to a combination of
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Summit Therapeutics Stock Smart Score
Company Description
Summit Therapeutics
Summit Therapeutics Inc. is a biopharmaceutical firm dedicated to discovering, developing, and commercializing therapeutic solutions, primarily targeting infectious diseases across the United States and Latin America. The company's clinical development pipeline is heavily concentrated on therapies for Clostridioides difficile infection (CDI). Its flagship product candidate, ridinilazole, is an orally administered small molecule antibiotic currently advancing through Phase III clinical trials as a treatment for CDI. Beyond its lead asset, Summit Therapeutics is also progressing SMT-738, designed to combat multidrug-resistant infections, notably carbapenem-resistant Enterobacteriaceae (CRE). Additionally, its DDS-04 series represents a potential therapeutic avenue for various infections caused by the Enterobacteriaceae family of bacteria. Established in 2003, the company maintains its headquarters in Cambridge, Massachusetts.
- Sector
- Healthcare
- Industry
- Biotechnology
- CEO
- Robert W. Duggan
- Employees
- 265
- Website
- www.smmttx.com
- Address
- 601 Brickell Key Drive, Miami, FL, 33131, US
Summit Therapeutics (SMMT) Earnings & Revenues
SMMT Company Deck
SMMT Earnings Call
Earnings Call SentimentPositive
The call emphasized substantial clinical progress for ivonescimab — multiple positive Phase III PFS readouts, overall survival hazard ratios consistently under 0.80, extensive global clinical activity, commercial exposure in China, and a strong cash balance with no debt. Key near-term catalysts include the FDA PDUFA date (Nov 14, 2026) and upcoming HARMONi-3 interim analyses. Offsetting risks include accelerating operating costs and cash burn, reliance on ATM financings, regulatory uncertainty around statistically significant OS for approval, and the statistical/operational complexity introduced by multiple interim OS looks and regional maturity differences. Overall, the positives around clinical data and pipeline breadth outweigh the financial and regulatory risks presented on the call.
View all SMMT earnings summariesSMMT Stock 12 Month Forecast
Average Price Target
Technical Analysis
Overall Consensus
| Indicator | Bullish | Neutral | Bearish |
|---|---|---|---|
| Overall Consensus | 11 | 5 | 6 |
| Technical Analysis | 3 | 5 | 2 |
| Moving Averages | 8 | 0 | 4 |










