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Serina Therapeutics (SER) AI Stock Analysis

SER

Serina Therapeutics

(NYSE MKT:SER)

Select Model
Rating:44Neutral
Price Target:$1.50â–¼(-23.86% Downside)
Action:reiterated
Date:10/10/26

Overall score is weighed down primarily by weak financial performance (no TTM revenue, sizable losses, and high ongoing cash burn), with technicals also negative as the stock trades below key moving averages and shows weak momentum. Corporate actions provide some support by improving capital-structure clarity and financing flexibility, but potential dilution and loss-making valuation characteristics keep the score in the low range.

Positive Factors
POZ drug-delivery platformThe POZ platform gives Serina a defined technology base for developing extended-release and targeted-delivery therapies. If its applications translate into viable candidates, the platform could support multiple programs and improve treatment profiles beyond a single drug asset.
Negative Factors
No current revenue and deep lossesThe absence of TTM revenue indicates that Serina has not yet achieved commercial operating scale, while substantial EBIT and net losses show that development costs are not being covered by business activity. This leaves performance dependent on future clinical and commercial progress.

Serina Therapeutics (SER) vs. SPDR S&P 500 ETF (SPY)

-80%-60%-40%-20%0%20%SER-55.17%SPY+11.79%Dec '25Jan '26Feb '26Mar '26Apr '26May '26Jun '26Jul '26Aug '26Sep '26Oct '26
Market Cap
$29.10M
Dividend Yield
―
Average Volume (3M)
70.20K
Price to Earnings (P/E)
-1.0
Beta (1Y)
0.22
Revenue Growth
―
EPS Growth
―
Country
US
Employees
16
Sector
Healthcare
Sector Strength
51
Industry
Biotechnology

Serina Therapeutics Business Overview & Revenue Model

Company Description

Serina Therapeutics, Inc., a biotechnology firm, focuses on creating pharmaceutical treatments for neurological conditions and pain. Its primary investigational drug, SER 252, is a POZ conjugate intended for managing Parkinson's disease. The company...

Serina Therapeutics Financial Statement Overview

Summary

Financials reflect a pre-commercial, high-cash-burn profile: TTM shows no revenue with large losses (EBIT -$25.7M; net loss -$21.2M) and significant negative free cash flow (-$21.2M). Balance sheet leverage is low (debt ~$0.12M vs. equity ~$18.7M), but historical equity volatility and ongoing losses elevate dilution/financing risk.

Income Statement

18Very Negative

Balance Sheet

54Neutral

Cash Flow

22Negative
Financial statement breakdown
BreakdownTTMDec 2025Dec 2024Dec 2023Mar 2023Dec 2021
Income Statement
Total Revenue0056.00K3.15M500.00K3.46M
Gross Profit-7.07M0-138.00K3.06M500.00K-333.84K
EBITDA-22.13M-18.91M-10.49M5.92M-2.60M-1.23M
Net Income-21.18M-19.18M-11.14M5.27M-2.68M-1.26M
Balance Sheet
Total Assets25.81M6.95M6.72M8.97M3.24M3.15M
Cash, Cash Equivalents and Short-Term Investments23.02M3.06M3.67M7.62M645.00K584.00K
Total Debt3.21M196.00K268.00K3.44M18.12M13.20M
Total Liabilities7.08M6.99M6.22M41.26M20.56M15.03M
Stockholders Equity18.73M-37.00K641.00K-32.29M-17.21M-11.83M
Cash Flow
Free Cash Flow-21.17M-17.95M-17.16M-2.98M-2.09M-2.36M
Operating Cash Flow-21.14M-17.95M-17.14M-2.48M-2.08M-2.25M
Investing Cash Flow-66.00K-59.00K-22.00K-504.00K980.94K823.32K
Financing Cash Flow38.18M17.41M13.21M10.07M1.31M1.08M

Serina Therapeutics Technical Analysis

Technical Analysis SentimentNeutral
Last Price1.97

Price Trends

50DMA2.15Negative
100DMA2.15Negative
200DMA2.09Negative

Market Momentum

MACD-0.10Negative
RSI52.33Neutral
STOCH67.78Neutral

Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For SER, the sentiment is Neutral. The current price of 1.97 is above the 20-day moving average (MA) of 1.82, below the 50-day MA of 2.15, and below the 200-day MA of 2.09, indicating a neutral trend. The MACD of -0.10 indicates Negative momentum. The RSI at 52.33 is Neutral, neither overbought nor oversold. The STOCH value of 67.78 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Neutral sentiment for SER.

Serina Therapeutics Risk Analysis

Serina Therapeutics disclosed 74 risk factors in its most recent earnings report. Serina Therapeutics reported the most risks in the "Finance & Corporate" category.

Higher RiskSector Avg.Lower RiskFinance & CorporateTech & InnovationLegal & RegulatoryProductionAbility to SellMacro & Political
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy

Latest Risks Added

3 New Risks
1.Our March 2026 purchase agreement involving a member of our Board of Directors and related governance arrangements may result in conflicts of interest, dilution, and increased investor influence over our affairs.Q2, 2026
2.Dr. Bailey and Juvenescence together hold a significant concentration of our common stock and are able to control or substantially influence matters requiring stockholder approval, which limits the ability of our other stockholders to influence corporate matters.Q2, 2026
3.We are operating under an accepted plan to regain compliance with the continued listing standards of the NYSE American; if we fail to regain and maintain compliance, our common stock could be delisted.Q2, 2026

Serina Therapeutics Peers Comparison

Overall Rating

UnderperformOutperform
Sector (51)

Financial Indicators

SER against its peers
NameOverall RatingMarket CapP/E RatioROEDividend YieldRevenue GrowthEPS Growth
Sector *51Neutral$7.86B-0.30-43.30%2.27%22.53%-2.21%
SERSER44Neutral$49.28M-1.03-222.42%―――
CELUCELU44Neutral$25.96M-0.45142.25%―-58.14%47.25%
SKYESKYE43Neutral$5.67M-0.13-329.08%――-19.07%
OTLKOTLK42Neutral$113.96M-0.42222.01%―――

* Healthcare Sector Average

Performance Comparison

-50%0%50%SEROTLKSKYECELUJUNSDec '25Jan '26Feb '26Mar '26Apr '26May '26Jun '26Jul '26Aug '26Sep '26Oct '26
SER and its peers over the selected period
Show on chartTickerCompany NamePriceChange% Change
SERSerina Therapeutics, Inc.1.94-2.74-58.55%
OTLKOutlook Therapeutics0.47-0.83-64.00%
SKYESkye Bioscience, Inc.1.28-10.72-89.33%
CELUCelularity Inc.0.80-0.92-53.49%
JUNSJupiter Neurosciences, Inc.2.05-96.95-97.93%

Serina Therapeutics Corporate Events

Business Operations and StrategyRegulatory Filings and Compliance

Serina Therapeutics Streamlines Capital Structure After Preferred Elimination

Positive
Oct 9, 2026

On October 5, 2026, Serina Therapeutics, Inc. filed a Certificate of Elimination in Delaware to remove all provisions related to its Series A Convertible Preferred Stock from its amended and restated certificate of incorporation. This action follows...

Business Operations and StrategyPrivate Placements and FinancingRegulatory Filings and Compliance

Serina Therapeutics Establishes Flexible Equity Financing Agreement

Positive
Aug 27, 2026

On August 21, 2026, Serina Therapeutics entered into a Common Stock Purchase Agreement and related Registration Rights Agreement with Roth Principal Investments, giving the company the discretionary right to sell up to $25 million of newly issued com...

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.

Date of analysis: Oct 10, 2026