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Atrium Therapeutics, Inc. (RNA)
NASDAQ:RNA
US Market
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Atrium Therapeutics, Inc. (RNA) AI Stock Analysis

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RNA

Atrium Therapeutics, Inc.

(NASDAQ:RNA)

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Neutral 50 (OpenAI - Gpt-5.6Sol)
Rating:50Neutral
Price Target:
$13.00
▼(-7.01% Downside)
Action:Reiterated
Date:08/19/26
The score is primarily held back by weak financial performance—large net losses and persistent, sizable cash burn—despite the benefit of low leverage. Technical indicators provide a partial offset with moderately positive momentum, while valuation is constrained by a negative P/E and no dividend yield data.
Positive Factors
Strategic BMS partnership and milestone economics
The Bristol Myers Squibb collaboration provides non-dilutive milestone potential, royalty upside and validation from a major pharmaceutical partner. BMS funding future clinical, regulatory and commercialization work could materially reduce Atrium’s development burden.
Negative Factors
Persistent cash burn and funding dependence
Sustained operating and free-cash-flow deficits indicate that Atrium cannot currently fund development from internal operations. Continued reliance on external capital may create dilution or financing risk and could constrain investment if funding conditions deteriorate.
Read all positive and negative factors
Positive Factors
Negative Factors
Strategic BMS partnership and milestone economics
The Bristol Myers Squibb collaboration provides non-dilutive milestone potential, royalty upside and validation from a major pharmaceutical partner. BMS funding future clinical, regulatory and commercialization work could materially reduce Atrium’s development burden.
Read all positive factors

Atrium Therapeutics, Inc. (RNA) vs. SPDR S&P 500 ETF (SPY)

Atrium Therapeutics, Inc. Business Overview & Revenue Model

Company Description
Atrium Therapeutics, Inc. is a biopharmaceutical company dedicated to revolutionizing the treatment of cardiomyopathies by delivering innovative ribonucleic acid (RNA) therapeutics directly to the heart. Their development-stage portfolio currently...

Atrium Therapeutics, Inc. Financial Statement Overview

Summary
Financials reflect a development-stage biotech profile: very small/volatile revenue, deeply negative profitability (TTM net loss ~ $259M), and heavy ongoing cash burn (TTM operating cash flow ~ -$210M; free cash flow ~ -$217M). The key offsetting strength is very low leverage (TTM debt-to-equity ~0.01), but balance sheet contraction and negative ROE (~ -39%) keep the financial performance score constrained.
Income Statement
23
Negative
Balance Sheet
64
Positive
Cash Flow
18
Very Negative
BreakdownTTMDec 2025Dec 2024Dec 2023Dec 2022Dec 2021
Income Statement
Total Revenue35.97M18.62M10.90M9.56M9.22M9.33M
Gross Profit35.48M18.62M10.90M7.46M7.84M-91.86M
EBITDA-260.06M-76.50M-376.16M-233.50M-177.53M-117.41M
Net Income-259.33M-76.68M-322.30M-212.22M-174.00M-118.01M
Balance Sheet
Total Assets280.51M278.35M1.56B628.55M638.80M427.58M
Cash, Cash Equivalents and Short-Term Investments264.21M270.00M1.50B595.35M610.73M405.54M
Total Debt1.68M3.67M6.80M9.85M10.69M11.73M
Total Liabilities65.94M71.07M138.94M127.79M60.73M46.15M
Stockholders Equity214.58M207.29M1.42B500.76M578.08M381.43M
Cash Flow
Free Cash Flow-217.39M-42.57M-307.94M-123.29M-139.09M-98.55M
Operating Cash Flow-210.49M-41.13M-300.87M-119.06M-136.27M-94.81M
Investing Cash Flow-782.49M-1.45M-854.20M-130.07M-189.96M-82.52M
Financing Cash Flow1.17B42.57M1.19B93.86M346.17M176.32M

Atrium Therapeutics, Inc. Technical Analysis

Technical Analysis Sentiment
Negative
Last Price13.98
Price Trends
50DMA
100DMA
200DMA
Market Momentum
MACD
0.14
Positive
RSI
58.43
Neutral
STOCH
29.36
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For RNA, the sentiment is Negative. The current price of 13.98 is equal to the 20-day moving average (MA) of ―, equal to the 50-day MA of ―, and equal to the 200-day MA of ―, indicating a neutral trend. The MACD of 0.14 indicates Positive momentum. The RSI at 58.43 is Neutral, neither overbought nor oversold. The STOCH value of 29.36 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Negative sentiment for RNA.

Atrium Therapeutics, Inc. Risk Analysis

Atrium Therapeutics, Inc. disclosed 92 risk factors in its most recent earnings report. Atrium Therapeutics, Inc. reported the most risks in the "Tech & Innovation" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

Atrium Therapeutics, Inc. Peers Comparison

Overall Rating
UnderperformOutperform
Sector (55)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
55
Neutral
$6.65B3.83-15.92%6.20%10.91%7.18%
53
Neutral
$397.38M-24.13-5.76%93.45%
52
Neutral
$459.60M-4.56-46.54%-82.95%-49.04%
51
Neutral
$231.85M-2.79-91.60%3472.96%67.74%
50
Neutral
$239.14M-3.54-39.08%
49
Neutral
$283.07M-1.76-57.61%-94.10%-122.58%
48
Neutral
$301.65M-1.62141.41%
* General Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
RNA
Atrium Therapeutics, Inc.
13.64
-1.11
-7.53%
ARCT
Arcturus Therapeutics
15.19
-1.82
-10.70%
RCKT
Rocket Pharmaceuticals
3.86
0.58
17.68%
RNAC
Cartesian Therapeutics
9.60
-0.45
-4.48%
DTIL
Precision BioSciences
7.78
2.88
58.78%
TRDA
Entrada Therapeutics Inc
7.00
1.53
27.97%
Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Aug 19, 2026