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Atrium Therapeutics, Inc. (RNA)
NASDAQ:RNA
US Market
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Atrium Therapeutics, Inc. (RNA) AI Stock Analysis

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RNA

Atrium Therapeutics, Inc.

(NASDAQ:RNA)

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Neutral 45 (OpenAI - Gpt-5.6Sol)
Rating:45Neutral
Price Target:
$8.00
▼(-41.35% Downside)
Action:Reiterated
Date:09/10/26
Overall score is held down primarily by weak financial performance (large losses and persistent cash burn) and a bearish trend indicated by price trading below key moving averages. Valuation contributes only modestly because the negative P/E reflects unprofitability and there is no dividend yield data to offset risk.
Positive Factors
Very Low Leverage
Very low leverage reduces refinancing and solvency pressure, preserving more financial flexibility than a similarly loss-making company with substantial debt. This gives Atrium greater room to manage funding needs and allocate capital while it works through its ongoing investment phase.
Negative Factors
Persistent Cash Burn
Persistent operating and free-cash-flow deficits indicate that the business is not internally funding its activities and remains reliant on external funding. This can pressure future capital allocation, increase dilution or financing needs, and limit resilience if losses continue over the next several quarters.
Read all positive and negative factors
Positive Factors
Negative Factors
Very Low Leverage
Very low leverage reduces refinancing and solvency pressure, preserving more financial flexibility than a similarly loss-making company with substantial debt. This gives Atrium greater room to manage funding needs and allocate capital while it works through its ongoing investment phase.
Read all positive factors

Atrium Therapeutics, Inc. (RNA) vs. SPDR S&P 500 ETF (SPY)

Atrium Therapeutics, Inc. Business Overview & Revenue Model

Company Description
Atrium Therapeutics, Inc. is a biopharmaceutical company dedicated to revolutionizing the treatment of cardiomyopathies by delivering innovative ribonucleic acid (RNA) therapeutics directly to the heart. Their development-stage portfolio currently...

Atrium Therapeutics, Inc. Financial Statement Overview

Summary
Financial profile is weak overall: minimal and volatile revenue, very large ongoing net and operating losses (TTM net loss ~ $259M), and heavy cash burn (TTM operating cash flow ~ -$210M; free cash flow ~ -$217M, worsening vs. prior period). The main offsetting positive is very low leverage (TTM debt-to-equity ~0.01), which reduces near-term solvency pressure, but profitability and cash flow remain major constraints.
Income Statement
23
Negative
Balance Sheet
64
Positive
Cash Flow
18
Very Negative
BreakdownTTMDec 2025Dec 2024Dec 2023Dec 2022Dec 2021
Income Statement
Total Revenue35.97M18.62M10.90M9.56M9.22M9.33M
Gross Profit35.48M18.62M10.90M7.46M7.84M-91.86M
EBITDA-260.06M-76.50M-376.16M-233.50M-177.53M-117.41M
Net Income-259.33M-76.68M-322.30M-212.22M-174.00M-118.01M
Balance Sheet
Total Assets280.51M278.35M1.56B628.55M638.80M427.58M
Cash, Cash Equivalents and Short-Term Investments264.21M270.00M1.50B595.35M610.73M405.54M
Total Debt1.68M3.67M6.80M9.85M10.69M11.73M
Total Liabilities65.94M71.07M138.94M127.79M60.73M46.15M
Stockholders Equity214.58M207.29M1.42B500.76M578.08M381.43M
Cash Flow
Free Cash Flow-217.39M-42.57M-307.94M-123.29M-139.09M-98.55M
Operating Cash Flow-210.49M-41.13M-300.87M-119.06M-136.27M-94.81M
Investing Cash Flow-782.49M-1.45M-854.20M-130.07M-189.96M-82.52M
Financing Cash Flow1.17B42.57M1.19B93.86M346.17M176.32M

Atrium Therapeutics, Inc. Risk Analysis

Atrium Therapeutics, Inc. disclosed 92 risk factors in its most recent earnings report. Atrium Therapeutics, Inc. reported the most risks in the "Tech & Innovation" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

Atrium Therapeutics, Inc. Peers Comparison

Overall Rating
UnderperformOutperform
Sector (55)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
55
Neutral
$6.65B3.83-15.92%6.20%10.91%7.18%
55
Neutral
$312.09M-3.32-46.54%1.29%-82.95%-49.04%
45
Neutral
$178.21M-2.08-42.90%―――
45
Neutral
$256.87M-13.75-5.76%――93.45%
44
Neutral
$193.48M-1.08141.41%―――
44
Neutral
$181.06M-1.17-57.61%―-94.10%-122.58%
43
Neutral
$181.07M-2.41-91.60%―3472.96%67.74%
* General Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
RNA
Atrium Therapeutics, Inc.
8.16
-6.59
-44.68%
ARCT
Arcturus Therapeutics
10.73
-1.27
-10.58%
RCKT
Rocket Pharmaceuticals
2.31
-1.43
-38.24%
RNAC
Cartesian Therapeutics
6.41
-2.59
-28.78%
DTIL
Precision BioSciences
6.78
-0.15
-2.16%
TRDA
Entrada Therapeutics Inc
4.73
-1.67
-26.09%
Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Sep 10, 2026