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PYXS Stock Chart & Stats
$1.66
-$0.10(-5.75%)
At close: 4:00 PM EST
$1.66
-$0.10(-5.75%)
Day’s Range― - ―
52-Week Range$0.97 - $5.55
Previous CloseN/A
Volume258.73K
Average Volume (3M)757.02K
Market Cap
$149.52M
Enterprise Value$68.43
Total Cash (Recent Filing)$42.49M
Total Debt (Recent Filing)$18.26M
Price to Earnings (P/E)―
Beta1.35
Next Earnings
Aug 19, 2026EPS Estimate
-0.34Next Dividend Ex-DateN/A
Dividend YieldN/A
Share Statistics
EPS (TTM)-1.31
Shares Outstanding63,355,480
10 Day Avg. Volume789,983
30 Day Avg. Volume757,017
Financial Highlights & Ratios
PEG Ratio0.30
Price to Book (P/B)1.34
Price to Sales (P/S)5.16
P/FCF Ratio-1.13
Enterprise Value/Market Cap<0.01
Enterprise Value/Revenue<0.01
Enterprise Value/Gross Profit<0.01
Enterprise Value/Ebitda>-0.01
Forecast
1Y Price Target
$6.50Price Target Upside291.57% Upside
Rating ConsensusStrong Buy
Number of Analyst Covering7
EPS Forecast (FY)-1.21
Revenue Forecast (FY)$58.33K
Bulls Say, Bears Say
Bulls Say
Extended Cash Runway Via FinancingThe June 2026 private placement materially strengthens near-term liquidity and extends runway into Q2 2027, reducing immediate funding pressure. This gives management time to advance MICVO trials, generate clinical readouts, and de-risk programs before needing dilutive financing.
Focused Immuno‑Oncology PipelinePyxis’s concentrated strategy on monoclonal antibodies and ADCs in immuno-oncology aligns with durable industry demand for targeted biologics. Specialization across modalities increases strategic optionality and potential for high-margin products if clinical programs translate to approvals.
Governance And Oversight StabilityBoard continuity from elected directors and appointment of a reputable audit firm strengthen governance and financial oversight. Robust oversight supports disciplined clinical development, regulatory compliance, and credible investor communications over the medium term.
Bears Say
Persistent High Cash BurnSustained ~-$67M annual cash outflow reflects ongoing R&D and operating costs that will require repeated capital raises absent commercialization. This persistent burn increases dilution risk and constrains investments in multiple programs, pressuring long-term financial flexibility.
Deep And Ongoing Operating LossesLarge, sustained losses signal the company is far from revenue-positive operations; negative margins limit internal funding for trials and commercialization. Continued unprofitability increases dependency on external capital and heightens risk if clinical milestones are delayed or unsuccessful.
Eroded Equity CushionA sharply reduced equity base and shrinking total assets weaken the balance-sheet buffer against setbacks. Even with moderate headline debt, limited equity reduces capacity to absorb trial failures or pursue opportunistic investments without materially dilutive financing.
Pyxis Oncology News
PYXS FAQ
What was Pyxis Oncology’s price range in the past 12 months?
Pyxis Oncology lowest stock price was $0.97 and its highest was $5.55 in the past 12 months.
What is Pyxis Oncology’s market cap?
Pyxis Oncology’s market cap is $149.52M.
When is Pyxis Oncology’s upcoming earnings report date?
Pyxis Oncology’s upcoming earnings report date is Aug 19, 2026 which is in 29 days.
How were Pyxis Oncology’s earnings last quarter?
Pyxis Oncology released its earnings results on May 14, 2026. The company reported -$0.37 earnings per share for the quarter, missing the consensus estimate of -$0.364 by -$0.006.
Is Pyxis Oncology overvalued?
According to Wall Street analysts Pyxis Oncology’s price is currently Undervalued.
Does Pyxis Oncology pay dividends?
Pyxis Oncology does not currently pay dividends.
What is Pyxis Oncology’s EPS estimate?
Pyxis Oncology’s EPS estimate is -0.34.
How many shares outstanding does Pyxis Oncology have?
Pyxis Oncology has 63,355,480 shares outstanding.
What happened to Pyxis Oncology’s price movement after its last earnings report?
Pyxis Oncology reported an EPS of -$0.37 in its last earnings report, missing expectations of -$0.364. Following the earnings report the stock price went down -15.649%.
Which hedge fund is a major shareholder of Pyxis Oncology?
Currently, no hedge funds are holding shares in PYXS
What is the TipRanks Smart Score and how is it calculated?
Smart Score combines eight research factors - such as analyst recommendations, hedge fund trends, and technical indicators - to measure a stock’s outlook. These signals are unified into a single score that reflects bullish or bearish momentum. See detailed methodology
Pyxis Oncology Stock Smart Score
Outperform
1
2
3
4
5
6
7
8
9
10
Analyst Consensus
Strong Buy
Average Price Target:
$6.50 (291.57% Upside)
$6.50 (291.57% Upside)
Hedge Fund Trend
Decreased
By 161.2K Shares
Last Quarter.
Last Quarter.
Crowd Wisdom
Very Positive
Last 7 Days ▲ 0.2%
Last 30 Days ▲ 4.9%
Last 30 Days ▲ 4.9%
News Sentiment
Very Bullish
Bullish news 100%
Bearish news 0%
Bearish news 0%
Technicals
SMA
Positive
20 days / 200 days
Momentum
148.23%
12-Months-Change
Fundamentals
Return on Equity
―
Trailing 12-Months
Asset Growth
-52.67%
Trailing 12-Months
Company Description
Pyxis Oncology
Pyxis Oncology, Inc. operates as a preclinical biopharmaceutical company focused on developing novel therapeutic approaches to combat various forms of cancer. Its investigational immune-oncology pipeline includes PYX-106, a fully human immunoglobulin G1 (IgG1) antibody designed to target siglec-15, which is being explored for its potential efficacy against thyroid cancer, head and neck squamous cell carcinoma, non-small cell lung cancer (NSCLC), and other solid tumors. Additionally, PYX-102 is an immune-therapeutic currently under investigation for the treatment of solid tumors. The company's portfolio also features a range of investigational antibody-drug conjugate (ADC) candidates: PYX-201, a novel ADC being developed for NSCLC, breast cancer, and other solid tumors; PYX-202, another novel ADC aimed at small cell lung cancer (SCLC), soft tissue sarcoma, and other solid tumors; and PYX-203, an ADC undergoing evaluation for acute myeloid leukemia and myeloid dysplastic syndrome. Pyxis Oncology was founded in 2018 and is based in Cambridge, Massachusetts.
PYXS Stock 12 Month Forecast
Average Price Target
$6.50
▲(291.57% Upside)
Technical Analysis
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Ownership Overview
2.81% Insiders
4.05% Mutual Funds
31.69% Other Institutional Investors
57.22% Public Companies and
Individual Investors










