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PRAX Stock Chart & Stats
$377.37
-$9.50(-2.92%)
At close: 4:00 PM EDT
$377.37
-$9.50(-2.92%)
Day’s Range― - ―
52-Week Range$154.45 - $392.70
Previous Close$315.8
Volume296.03K
Average Volume (3M)485.68K
Market Cap
$7.26B
Enterprise Value$9.00B
Total Cash (Recent Filing)$758.55M
Total Debt (Recent Filing)$1.09M
Price to Earnings (P/E)―
Beta2.32
Next Earnings
Nov 11, 2026EPS Estimate
-3.54Next Dividend Ex-DateN/A
Dividend YieldN/A
Share Statistics
EPS (TTM)-12.95
Shares Outstanding27,919,989
10 Day Avg. Volume559,970
30 Day Avg. Volume485,684
Financial Highlights & Ratios
PEG Ratio-0.68
Price to Book (P/B)7.55
Price to Sales (P/S)0.00
P/FCF Ratio-26.63
Enterprise Value/Market Cap1.24
Enterprise Value/RevenueN/A
Enterprise Value/Gross Profit-62.76
Enterprise Value/Ebitda-26.53
Forecast
1Y Price Target
$702.18Price Target Upside86.07% Upside
Rating ConsensusStrong Buy
Number of Analyst Covering17
EPS Forecast (FY)-13.71
Revenue Forecast (FY)$925.48K
Bulls Say, Bears Say
Bulls Say
Strong Balance SheetExtremely low leverage and substantial liquidity give Praxis financial flexibility to fund clinical development and planned launches. The reported runway into 2028 reduces near-term financing pressure, allowing management to pursue multiple CNS programs while maintaining strategic options.
Favorable FDA ProgressLate-stage regulatory reviews without identified efficacy issues or advisory committees improve the visibility of potential product approvals. The clean BIMO inspection also supports confidence in clinical operations and data integrity as Praxis approaches important regulatory decisions.
Commercial Launch ReadinessBuilding commercial capabilities before expected decisions positions Praxis to convert approvals into product access without starting from zero. Established teams, distribution planning, inventory, and patient-support infrastructure can support a coordinated launch across targeted CNS markets.
Bears Say
No Durable Revenue BasePraxis remains dependent on successful clinical development and future approvals because it currently has no durable TTM revenue base. Large operating and net losses show that the business has not yet demonstrated commercial earnings power or self-funding operations.
Persistent Cash BurnSustained negative cash flow increases the resources required to advance trials and prepare launches, even with a strong current liquidity position. Rising operating expenses and cash use could shorten financial flexibility if commercialization takes longer or requires additional investment.
Clinical Execution SetbackThe POWER1 primary-endpoint miss weakens confidence in the vormatrigine development path and creates additional execution risk. Trial redesign, restarting studies, and added time and cost may delay potential approval, while the secondary result does not remove primary-endpoint uncertainty.
PRAX FAQ
What was Praxis Precision Medicines’s price range in the past 12 months?
Praxis Precision Medicines lowest stock price was $154.45 and its highest was $392.70 in the past 12 months.
What is Praxis Precision Medicines’s market cap?
Praxis Precision Medicines’s market cap is $7.26B.
When is Praxis Precision Medicines’s upcoming earnings report date?
Praxis Precision Medicines’s upcoming earnings report date is Nov 11, 2026 which is in 20 days.
How were Praxis Precision Medicines’s earnings last quarter?
Praxis Precision Medicines released its earnings results on Aug 06, 2026. The company reported -$2.87 earnings per share for the quarter, beating the consensus estimate of -$3.668 by $0.798.
Is Praxis Precision Medicines overvalued?
According to Wall Street analysts Praxis Precision Medicines’s price is currently Undervalued.
Does Praxis Precision Medicines pay dividends?
Praxis Precision Medicines does not currently pay dividends.
What is Praxis Precision Medicines’s EPS estimate?
Praxis Precision Medicines’s EPS estimate is -3.54.
How many shares outstanding does Praxis Precision Medicines have?
Praxis Precision Medicines has 27,919,989 shares outstanding.
What happened to Praxis Precision Medicines’s price movement after its last earnings report?
Praxis Precision Medicines reported an EPS of -$2.87 in its last earnings report, beating expectations of -$3.668. Following the earnings report the stock price went up 15.954%.
Which hedge fund is a major shareholder of Praxis Precision Medicines?
Currently, no hedge funds are holding shares in PRAX
What is the TipRanks Smart Score and how is it calculated?
Smart Score combines eight research factors - such as analyst recommendations, hedge fund trends, and technical indicators - to measure a stock’s outlook. These signals are unified into a single score that reflects bullish or bearish momentum. See detailed methodology
Praxis Precision Medicines Stock Smart Score
Neutral
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9
10
Analyst Consensus
Strong Buy
Average Price Target:
$702.18 (86.07% Upside)
$702.18 (86.07% Upside)
Blogger Sentiment
Bullish
PRAX Sentiment 100%
Sector Average 67%
Sector Average 67%
Hedge Fund Trend
Decreased
By 355.4K Shares
Last Quarter.
Last Quarter.
Crowd Wisdom
Neutral
Last 7 Days ▼ 1.1%
Last 30 Days ▲ 1.8%
Last 30 Days ▲ 1.8%
News Sentiment
Very Bullish
Bullish news 100%
Bearish news 0%
Bearish news 0%
Technicals
SMA
Negative
20 days / 200 days
Momentum
51.07%
12-Months-Change
Fundamentals
Return on Equity
-34.15%
Trailing 12-Months
Asset Growth
206.98%
Trailing 12-Months
Learn more about TipRanks Smart Score
Company Description
Praxis Precision Medicines
Praxis Precision Medicines, Inc. is a biopharmaceutical firm operating at the clinical stage, dedicated to creating innovative treatments for central nervous system (CNS) conditions that stem from an imbalance in neuronal activity. The company's primary investigational compounds currently undergoing evaluation include: PRAX-114, an extrasynaptic-preferring positive allosteric modulator of the GABAA receptor, which is currently in Phase IIa clinical trials for addressing both major depressive disorder and perimenopausal depression. Additionally, PRAX-944, a small molecule designed to selectively inhibit T-type calcium channels, is also progressing through Phase IIa clinical trials to manage essential tremor. Beyond these, Praxis is also advancing a pipeline of other promising drug candidates, such as: PRAX-562, a persistent sodium current blocker, undergoing Phase I clinical evaluation for treating severe pediatric epilepsy and adult cephalgia (headaches). PRAX-222, an antisense oligonucleotide (ASO) aimed at individuals suffering from gain-of-function (GOF) SCN2A epilepsy. And a program targeting KCNT1 for the treatment of KCNT1 GOF epilepsy. To further its research and development efforts, Praxis maintains several strategic alliances. These include a cooperation and licensing arrangement with RogCon Inc.; a licensing deal with Purdue Neuroscience Company; a comprehensive research collaboration, option, and license agreement with Ionis Pharmaceuticals, Inc.; and a collaborative project with The Florey Institute focused on the creation of three new antisense oligonucleotides (ASOs). Established in 2015, the company's headquarters are situated in Boston, Massachusetts.
PRAX Earnings Call
Q2 2026
0:00 / 0:00
Earnings Call Sentiment|Positive
The call showed strong positive momentum: two late-stage NDAs with favorable FDA mid-cycle feedback and no advisory committees, a clean FDA BIMO inspection, solid commercial build and a robust cash position providing runway into 2028. Clinical progress was highlighted by EMERALD over-enrollment and another BTD for elsunersen. Offsetting risks include a failed primary in vormatrigine (being addressed by redesign), higher near-term operating spend and a relutrigine review extension. On balance, the significant regulatory, commercial and financial positives outweigh the operational and clinical setbacks.View all PRAX earnings summariesPRAX Stock 12 Month Forecast
Average Price Target
$702.18
▲(86.07% Upside)
Technical Analysis
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Ownership Overview
0.68% Insiders
25.16% Mutual Funds
0.03% Other Institutional Investors
56.97% Public Companies and
Individual Investors











