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Illumina (MX:ILMN)
:ILMN
Mexico Market
EarningsQ2 2026 Earnings Report

Illumina (ILMN) Q2 2026 Earnings Report

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MX:ILMN Q2 2026 EPS Results

Actual EPS$22.15
Consensus EPS$20.73
Beat/MissBeat by +$1.42
One Year Ago EPS$20.13

MX:ILMN Q2 2026 Revenue Results

Actual Revenue$19.64B
Expected Revenue$19.12B
Beat/MissBeat by +$514.16M
YoY Revenue Growth+9.84%

Earnings Announcement Details

QuarterQ2 2026
Date07/30/2026
TimeAfter Close
Conference CallThursday, July 30, 2026
MX:ILMN Upcoming Earnings
Illumina's next earnings date is estimated for October 29, 2026, based on past reporting schedules.

Q2 2026 Earnings Call Audio

MX:ILMN Q2 2026 Earnings Call
0:00 / 0:00

Q2 2026 Earnings Slide Deck

Q2 2026 Earnings Call Summary

Q2 2026
Earnings Call Date:Jul 30, 2026|
% Change Since:
|
Earnings Call Sentiment|Positive
The call was broadly positive: Illumina delivered a quarter with strong top-line beats, materially higher instrument placements (especially NovaSeq X), margin outperformance, raised full-year guidance and strengthened multi-omics and BioInsight momentum (Billion Cell Atlas revenue and partners). Headwinds remain—memory and freight costs, inventory/tax timing impacts, and continued weakness in research consumables and some regions—but management has absorbed costs, secured supply, and raised guidance while reaffirming long-term targets. The positive operational and financial beats and the upgraded outlook outweigh the listed challenges.
Company Guidance
Following a strong Q2 (revenue $1.16B; rest‑of‑world organic growth 8.1%; non‑GAAP gross margin 68.2%; non‑GAAP operating margin 22.5%; non‑GAAP EPS $1.31), Illumina raised its 2026 outlook: full‑year rest‑of‑world organic revenue growth is now guided greater than 5% (up from 2–4%), reported revenue guidance was increased by $50M at the midpoint to $4.60–4.64B, and sequencing consumables rest‑of‑world organic is expected to grow mid‑single‑digits with clinical consumables up mid‑teens and research/applied consumables down mid‑to‑high single‑digits; sequencing instruments are now expected to grow low‑single‑digits rest‑of‑world organic. The company maintained non‑GAAP operating margin guidance of 23.4%–23.6% and raised full‑year diluted non‑GAAP EPS to $5.30–$5.40 (up $0.12 at the midpoint; ~11% y/y at midpoint, ~14% ex‑acquisitions). For Q3, management expects ~4.5% rest‑of‑world organic growth, reported revenue of $1.14–1.16B, non‑GAAP EPS $1.33–1.38 and ~24% operating margin (≈150 bps sequential expansion). Management reiterated that elevated NovaSeq X placements (Q2 placements >95) and an expanding X installed base (≈78% of clinical volume on X, ~83% of volumes and 59% of revenue transitioned overall; clinical conversion target ~80–85% by year‑end) will drive consumables pull‑through into 2027 and support the path to high‑single‑digit revenue growth next year.
Revenue Beat and Growth
Q2 revenue of $1.16B, up 9.5% year-over-year reported and ~6.5% organic; Rest-of-World organic revenue growth of 8.1%. Management called this the fastest revenue growth since the CEO joined.
Raised Full-Year Guidance
Raised full-year Rest-of-World organic revenue guidance to greater than 5% (up from prior 2%-4%); increased reported revenue midpoint by $50M to a $4.60B–$4.64B range.
EPS and Profitability Outperformance
Non-GAAP EPS of $1.31 in Q2, up ~10% year-over-year (≈13% ex-acquisitions); non-GAAP gross margin 68.2% and non-GAAP operating margin 22.5%—both above guidance. Full-year diluted EPS guidance raised to $5.30–$5.40 (≈11% y/y at midpoint, 14% ex-acquisitions).
Strong NovaSeq X Demand and Placements
Placed more than 95 NovaSeq X systems in Q2; management highlighted sustained elevated placements over recent quarters and expects continued elevated placements in H2 2026.
Sequencing Consumables Momentum (Clinical)
Sequencing consumables revenue $775M, up 5% year-over-year; clinical sequencing consumables grew ~15% ex-China with U.S./Canada region growing above 20%.
Instruments and Throughput Gains
Sequencing instruments revenue of $125M, up 31% year-over-year driven by NovaSeq X and MiSeq i100 placements; total sequencing gigabase output on connected mid/high-throughput instruments grew >30% year-over-year.
Service and New Programs Contribution
Sequencing service & other revenue $154M, up 14% YoY; Billion Cell Atlas has delivered >300M cells to date, added 3 pharma partners post-quarter (total six), and has begun booking revenue.
Successful M&A / Product Integration
SomaLogic integration contributing: Microarrays & other revenue $105M, up 21% reported (SomaLogic tracking toward high end of deal expectations). Launched StrataMap Spatial and whole genome MRD research workflow (early access).
Strong Cash Generation and Capital Allocation
Q2 operating cash flow $201M and free cash flow $162M; repurchased 0.9M shares for ~$122M; ~$1.17B cash & short-term investments, $1.99B total debt, ~1.6x gross debt/LTM EBITDA, ~$1.8B remaining buyback authorization.
Maintained Long-Term Financial Targets
Management reiterated progress toward 2027 targets, maintained operating margin guidance (23.4%–23.6%) and expects consumables-driven margin expansion (Q3 operating margin ~24%).

MX:ILMN Earnings History

Report Date
Fiscal Quarter
Forecast / EPS
Last Year's EPS
EPS YoY Change
Press Release
Oct 29, 2026
2026 (Q3)
22.93 / -
22.662―
2026 (Q2)
20.73 / 22.15
20.12510.08% (+2.03)
2026 (Q1)
17.84 / 19.45
16.40518.56% (+3.04)
2025 (Q4)
21.00 / 22.83
16.06742.11% (+6.76)
2025 (Q3)
19.75 / 22.66
19.2817.54% (+3.38)
2025 (Q2)
17.12 / 20.13
6.088230.56% (+14.04)
2025 (Q1)
15.90 / 16.40
1.4711014.94% (+14.93)
2024 (Q4)
15.44 / 16.07
2.3598.53% (+13.77)
2024 (Q3)
14.87 / 19.28
5.429255.14% (+13.85)
2024 (Q2)
1.86 / 6.09
5.2615.76% (+0.83)
The table shows recent earnings report dates and whether the forecast was beat or missed. See the change in forecast and EPS from the previous year.
Beat
Missed