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Arrowhead Pharmaceuticals (ARWR) Drug Pipeline

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Drug pipeline
Drug NameConditionStageStatusStudy NameTrial Start DateArticle
Aro-033Healthy ParticipantsPhase IRecruitingA First-In-Human Study of ARO-033 in Adult ParticipantsJun 18, 2026―
Zodasiran, Aro-Ang3Homozygous Familial HypercholesterolemiaPhase IIINot Yet RecruitingStudy of Zodasiran in Adolescent Participants With Homozygous Familial HypercholesterolemiaMar 11, 2026
Aro-RageAsthmaPhase IIRecruitingStudy of Inhaled ARO-RAGE in Allergen-induced Mild AsthmaNov 17, 2025
Aro-DimerpaHyperlipidemia; Mixedphase1AndPhase2RecruitingStudy of ARO-DIMERPA in Adult Participants With Mixed HyperlipidemiaOct 30, 2025
Aro-Mapt-ScAlzheimer Disease, Alzheimer Disease, Early Onsetphase1AndPhase2RecruitingStudy of ARO-MAPT-SC in Healthy Subjects and Subjects With Early Alzheimer's DiseaseOct 23, 2025
Zodasiran InjectionHomozygous Familial HypercholesterolemiaPhase IIIRecruitingA Phase 3 Study of Zodasiran in Adolescent and Adult Subjects With Homozygous Familial Hypercholesterolemia (YOSEMITE)Jun 17, 2025
Aro-Alk7Obesity, Diabetes Mellitus, Type 2phase1AndPhase2RecruitingA First-In-Human Study of ARO-ALK7 in Adults With Obesity With and Without Type 2 Diabetes MellitusApr 15, 2025
PlozasiranSevere HypertriglyceridemiaPhase IIIRecruitingStudy of Plozasiran in Adults With Severe Hypertriglyceridemia at Risk of Acute PancreatitisMar 12, 2025
Plozasiran InjectionHypertriglyceridemiaPhase IIIRecruitingLong-Term Safety and Efficacy of Plozasiran in Adults With HypertriglyceridemiaFeb 07, 2025
Tirzepatide, Aro-InhbeObesityphase1AndPhase2RecruitingA First-In-Human Study of ARO-INHBE in Adults With Obesity With and Without Type 2 Diabetes MellitusNov 20, 2024

FAQ

What are the FDA phases for drug approval?
The FDA approval process for new drugs is divided into several phases: a. Preclinical testing b. Phase 1 – Safety and dosage c. Phase 2 – Effectiveness and side effects d. Phase 3 – Confirmation of effectiveness, monitoring of adverse reactions, and comparison with existing treatments e. Phase 4 – Post-marketing studies to track long-term safety and effectiveness
What is a clinical trial?
A clinical trial is a carefully designed study in which researchers test a drug, treatment, or medical device in people to evaluate its safety, effectiveness, and potential side effects. These trials are essential for determining whether a new treatment should be approved for widespread use.
What drugs does Arrowhead Pharmaceuticals, Inc. (MX:ARWR) have in its pipeline
Arrowhead Pharmaceuticals MX:ARWR is currently developing the following drugs: Aro-033, Zodasiran, Aro-Ang3, Aro-Rage, Aro-Dimerpa, Aro-Mapt-Sc, Zodasiran Injection, Aro-Alk7, Plozasiran, Plozasiran Injection, Tirzepatide, Aro-Inhbe, Aro-Atxn2 Injection, Aro-Cfb, Aro-Dm1 For Injection, Aro-Dux4 For Injection, Vsa001 Injection, Aro-Mmp7 Inhalation Solution, Aro-Apoc3, Aro-Muc5ac, Aro-Ang 3 Injection, Aro-C3, Aro-Ang3, Aro-Enac, Sterile Normal Saline, Aro-Hsd Injection, Aro-Hif2, Fazisiran Injection, Aro-Aat, Sterile Normal Saline, Aro-Hbv, Jnj-56136379. These drug candidates are in various stages of clinical development as the company works toward FDA approval.