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Metagenomi, Inc. (MGX)
NASDAQ:MGX
US Market
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Metagenomi, Inc. (MGX) AI Stock Analysis

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MGX

Metagenomi, Inc.

(NASDAQ:MGX)

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Neutral 45 (OpenAI - Gpt-5.6Sol)
Rating:45Neutral
Price Target:
$0.98
▼(-19.42% Downside)
Action:Reiterated
Date:09/22/26
The score is primarily held down by weak financial performance (large losses, falling revenue, and significant cash burn). Technicals also lean negative with the stock below major moving averages and bearish momentum, despite oversold readings. A supportive recent corporate update and stated cash runway provides some offset, while valuation signals are constrained due to negative earnings and no dividend.
Positive Factors
Proprietary gene-editing platform
Metagenomi’s proprietary gene-editing technologies provide a differentiated foundation for developing internal therapies and partnering with biopharmaceutical companies. If the platform produces repeatable therapeutic applications, it can support multiple programs, licensing opportunities, milestones, and longer-term royalties.
Negative Factors
Falling revenue
The material revenue decline indicates that current collaboration, licensing, or service activity is not yet producing a steadily expanding commercial base. Weakening revenue makes operating expenses harder to absorb and increases reliance on future partnerships, milestones, or additional financing to sustain development.
Read all positive and negative factors
Positive Factors
Negative Factors
Proprietary gene-editing platform
Metagenomi’s proprietary gene-editing technologies provide a differentiated foundation for developing internal therapies and partnering with biopharmaceutical companies. If the platform produces repeatable therapeutic applications, it can support multiple programs, licensing opportunities, milestones, and longer-term royalties.
Read all positive factors

Metagenomi, Inc. (MGX) vs. SPDR S&P 500 ETF (SPY)

Metagenomi, Inc. Business Overview & Revenue Model

Company Description
Metagenomi, Inc. operates as a biotechnology company focused on gene editing, committed to developing therapeutic solutions for patients. The company utilizes a distinctive genome editing toolkit, sourced from metagenomics, for its development eff...
How the Company Makes Money
Metagenomi’s primary way of generating revenue is through research collaborations and strategic partnerships in which it licenses or provides access to its gene-editing platform (including engineered nucleases and related intellectual property) to...

Metagenomi, Inc. Financial Statement Overview

Summary
Financials are weak overall: despite strong gross margins (~76% TTM), the company is deeply unprofitable (operating margin ~-488%, net margin ~-689%), revenue declined materially (TTM down ~39%), and cash burn is substantial (TTM operating cash flow about -$85.5M and free cash flow about -$85.8M). Balance sheet leverage is not excessive (debt-to-equity ~0.34), but ongoing losses are eroding equity and increase financing risk.
Income Statement
24
Negative
Balance Sheet
58
Neutral
Cash Flow
18
Very Negative
BreakdownTTMDec 2025Dec 2024Dec 2023Dec 2022Dec 2021
Income Statement
Total Revenue13.56M25.21M52.30M44.76M17.20M243.00K
Gross Profit10.07M19.89M52.30M-49.65M15.47M-144.00K
EBITDA-88.49M-82.61M-78.16M-56.02M-39.19M-20.75M
Net Income-93.46M-87.87M-78.06M-68.25M-43.59M-21.44M
Balance Sheet
Total Assets173.70M221.10M324.60M364.84M414.49M141.99M
Cash, Cash Equivalents and Short-Term Investments120.66M160.80M248.31M271.18M362.13M108.15M
Total Debt37.72M40.66M45.78M48.23M18.57M48.93M
Total Liabilities61.13M62.51M89.74M500.43M488.91M174.54M
Stockholders Equity112.57M158.60M234.86M-135.58M-74.43M-32.54M
Cash Flow
Free Cash Flow-85.80M-89.47M-112.19M-101.22M15.75M21.35M
Operating Cash Flow-85.49M-88.89M-109.07M-91.41M29.72M24.26M
Investing Cash Flow96.88M103.53M-88.16M45.73M-122.20M-74.32M
Financing Cash Flow-73.00K-356.00K84.01M1.01M239.59M39.92M

Metagenomi, Inc. Technical Analysis

Technical Analysis Sentiment
Negative
Last Price1.21
Price Trends
50DMA
1.16
Negative
100DMA
1.21
Negative
200DMA
1.36
Negative
Market Momentum
MACD
-0.05
Positive
RSI
33.23
Neutral
STOCH
15.31
Positive
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For MGX, the sentiment is Negative. The current price of 1.21 is above the 20-day moving average (MA) of 1.10, above the 50-day MA of 1.16, and below the 200-day MA of 1.36, indicating a bearish trend. The MACD of -0.05 indicates Positive momentum. The RSI at 33.23 is Neutral, neither overbought nor oversold. The STOCH value of 15.31 is Positive, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Negative sentiment for MGX.

Metagenomi, Inc. Risk Analysis

Metagenomi, Inc. disclosed 77 risk factors in its most recent earnings report. Metagenomi, Inc. reported the most risks in the "Tech & Innovation" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

Metagenomi, Inc. Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
54
Neutral
$180.12M1.0272.96%6.79%-100.00%―
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
50
Neutral
$47.61M-1.33-166.98%――55.37%
45
Neutral
$37.78M-0.40-63.65%―-59.84%-5.97%
44
Neutral
$27.95M-0.62-82.06%――-23.49%
43
Neutral
$111.75M-1.71-157.89%――50.66%
42
Neutral
$95.16M-8.0944.67%―-96.72%-253.97%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
MGX
Metagenomi, Inc.
1.00
-1.85
-64.91%
ORMP
Oramed Pharm
4.33
2.08
92.79%
IMUX
Immunic
8.19
-0.76
-8.45%
ATRA
Atara Biotherapeutics
9.48
-5.56
-36.97%
HOWL
Werewolf Therapeutics
0.98
-0.65
-39.94%
CNTX
Context Therapeutics
0.30
-1.11
-78.44%

Metagenomi, Inc. Corporate Events

Business Operations and StrategyFinancial DisclosuresProduct-Related Announcements
Metagenomi updates hemophilia A gene editing program
Positive
Sep 22, 2026
In September 2026, Metagenomi Therapeutics, Inc. presented a corporate update outlining its progress as an in vivo gene editing company, anchored by lead program MGX-001 for hemophilia A and a broader pipeline in cardiometabolic and other genetic ...
Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Sep 22, 2026