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Medtronic (MDT) Drug Pipeline
| Drug Name | Condition | Stage | Status | Study Name | Trial Start Date | Article |
|---|---|---|---|---|---|---|
| Metoprolol Succinate, Bucindolol Hydrochloride | Current Or Recent History Of Atrial Fibrillation | Phase II | Completed | Genetically Targeted Therapy for the Prevention of Symptomatic Atrial Fibrillation in Patients With Heart Failure | Oct 23, 2013 | ― |
| Crt, No-Crt | Heart Failure | Phase IV | Completed | Medtronic South Asian Systolic Heart Failure Registry | Sep 13, 2011 | ― |
| Snn0029 | Amyotrophic Lateral Sclerosis | phase1AndPhase2 | Terminated | An Open Label, Safety and Tolerability Continuation Study of Intracerebroventricular Administration of sNN0029 to Patients With Amyotrophic Lateral Sclerosis | Jun 23, 2011 | ― |
| Ablation, Rate Control | Heart Failure, Atrial Fibrillation | Phase IV | Terminated | PAF-HEFT (Permanent Atrial Fibrillation in Heart Failure Trial) | Jan 13, 2009 | ― |
| Lv Dp/Dt Pressure Measurement | Heart Failure | Phase IV | Completed | Cardiac Resynchronization Therapy (CRT)-Narrow-dp/Dt-Study | Jan 13, 2009 | ― |
| Access Arm | Heart Failure | Phase IV | Completed | OptiLink HF Study: Optimization of Heart Failure Management Using Medtronic OptiVol Fluid Status Monitoring and CareLink Network | Oct 08, 2008 | ― |
| Rf Ablation Procedure | Paroxysmal Atrial Fibrillation | Phase IV | Completed | Ablation of the Pulmonary Veins for Paroxysmal Afib | Aug 28, 2008 | ― |
| Arctic Front Cryoablation Catheter, Flecainide Or Sotalol Or Propafenone | Paroxysmal Atrial Fibrillation | Phase III | Completed | A Clinical Study of the Arctic Front Cryoablation Balloon for the Treatment of Paroxysmal Atrial Fibrillation | Aug 31, 2007 | ― |
| Conducted Af-Response Algorithm On, Conducted Af-Response Algorithm Off | Heart Failure, Atrial Fibrillation, Sudden Cardiac Death | Phase IV | Terminated | CORE: Study to Evaluate the Conducted AF-Response-Algorithm in Patients Suffering From Heart Failure and Atrial Fibrillation | Sep 13, 2005 | ― |
| Use Of An Implantable Loop Recorder | Syncope | Phase IV | Completed | ELIAS: Early Loop-Recorder in Suspected Arrhythmogenic Syncope | Sep 12, 2005 | ― |
| Drug Name | Stage | Condition | Status | Study Name | Trial Start Date | Article |
|---|---|---|---|---|---|---|
| Metoprolol Succinate, Bucindolol Hydrochloride | Phase II | Current Or Recent History Of Atrial Fibrillation | Completed | Genetically Targeted Therapy for the Prevention of Symptomatic Atrial Fibrillation in Patients With Heart Failure | Oct 23, 2013 | ― |
| Crt, No-Crt | Phase IV | Heart Failure | Completed | Medtronic South Asian Systolic Heart Failure Registry | Sep 13, 2011 | ― |
| Snn0029 | phase1AndPhase2 | Amyotrophic Lateral Sclerosis | Terminated | An Open Label, Safety and Tolerability Continuation Study of Intracerebroventricular Administration of sNN0029 to Patients With Amyotrophic Lateral Sclerosis | Jun 23, 2011 | ― |
| Ablation, Rate Control | Phase IV | Heart Failure, Atrial Fibrillation | Terminated | PAF-HEFT (Permanent Atrial Fibrillation in Heart Failure Trial) | Jan 13, 2009 | ― |
| Lv Dp/Dt Pressure Measurement | Phase IV | Heart Failure | Completed | Cardiac Resynchronization Therapy (CRT)-Narrow-dp/Dt-Study | Jan 13, 2009 | ― |
| Access Arm | Phase IV | Heart Failure | Completed | OptiLink HF Study: Optimization of Heart Failure Management Using Medtronic OptiVol Fluid Status Monitoring and CareLink Network | Oct 08, 2008 | ― |
| Rf Ablation Procedure | Phase IV | Paroxysmal Atrial Fibrillation | Completed | Ablation of the Pulmonary Veins for Paroxysmal Afib | Aug 28, 2008 | ― |
| Arctic Front Cryoablation Catheter, Flecainide Or Sotalol Or Propafenone | Phase III | Paroxysmal Atrial Fibrillation | Completed | A Clinical Study of the Arctic Front Cryoablation Balloon for the Treatment of Paroxysmal Atrial Fibrillation | Aug 31, 2007 | ― |
| Conducted Af-Response Algorithm On, Conducted Af-Response Algorithm Off | Phase IV | Heart Failure, Atrial Fibrillation, Sudden Cardiac Death | Terminated | CORE: Study to Evaluate the Conducted AF-Response-Algorithm in Patients Suffering From Heart Failure and Atrial Fibrillation | Sep 13, 2005 | ― |
| Use Of An Implantable Loop Recorder | Phase IV | Syncope | Completed | ELIAS: Early Loop-Recorder in Suspected Arrhythmogenic Syncope | Sep 12, 2005 | ― |
FAQ
What are the FDA phases for drug approval?
The FDA approval process for new drugs is divided into several phases: a. Preclinical testing b. Phase 1 – Safety and dosage c. Phase 2 – Effectiveness and side effects d. Phase 3 – Confirmation of effectiveness, monitoring of adverse reactions, and comparison with existing treatments e. Phase 4 – Post-marketing studies to track long-term safety and effectiveness
What is a clinical trial?
A clinical trial is a carefully designed study in which researchers test a drug, treatment, or medical device in people to evaluate its safety, effectiveness, and potential side effects. These trials are essential for determining whether a new treatment should be approved for widespread use.
What drugs does Medtronic (MDT) have in its pipeline
Medtronic MDT is currently developing the following drugs: Metoprolol Succinate, Bucindolol Hydrochloride, Crt, No-Crt, Snn0029, Ablation, Rate Control, Lv Dp/Dt Pressure Measurement, Access Arm, Rf Ablation Procedure, Arctic Front Cryoablation Catheter, Flecainide Or Sotalol Or Propafenone, Conducted Af-Response Algorithm On, Conducted Af-Response Algorithm Off, Use Of An Implantable Loop Recorder, Icd Ablation Plus Vt-Ablation, Icd Therapy, Crt-P Or Crt-D Device, Search Av+ Algorithm, Medtronic At500. These drug candidates are in various stages of clinical development as the company works toward FDA approval.